全文获取类型
收费全文 | 19301篇 |
免费 | 1683篇 |
国内免费 | 559篇 |
专业分类
耳鼻咽喉 | 821篇 |
儿科学 | 160篇 |
妇产科学 | 80篇 |
基础医学 | 579篇 |
口腔科学 | 65篇 |
临床医学 | 2586篇 |
内科学 | 6510篇 |
皮肤病学 | 63篇 |
神经病学 | 313篇 |
特种医学 | 1034篇 |
外科学 | 4083篇 |
综合类 | 2737篇 |
预防医学 | 527篇 |
眼科学 | 121篇 |
药学 | 1134篇 |
18篇 | |
中国医学 | 228篇 |
肿瘤学 | 484篇 |
出版年
2024年 | 62篇 |
2023年 | 457篇 |
2022年 | 886篇 |
2021年 | 946篇 |
2020年 | 1027篇 |
2019年 | 795篇 |
2018年 | 853篇 |
2017年 | 770篇 |
2016年 | 925篇 |
2015年 | 838篇 |
2014年 | 1594篇 |
2013年 | 1476篇 |
2012年 | 1212篇 |
2011年 | 1308篇 |
2010年 | 979篇 |
2009年 | 949篇 |
2008年 | 971篇 |
2007年 | 904篇 |
2006年 | 739篇 |
2005年 | 631篇 |
2004年 | 547篇 |
2003年 | 408篇 |
2002年 | 326篇 |
2001年 | 253篇 |
2000年 | 232篇 |
1999年 | 186篇 |
1998年 | 185篇 |
1997年 | 163篇 |
1996年 | 123篇 |
1995年 | 123篇 |
1994年 | 116篇 |
1993年 | 99篇 |
1992年 | 74篇 |
1991年 | 77篇 |
1990年 | 66篇 |
1989年 | 42篇 |
1988年 | 36篇 |
1987年 | 31篇 |
1986年 | 22篇 |
1985年 | 21篇 |
1984年 | 14篇 |
1983年 | 15篇 |
1982年 | 23篇 |
1981年 | 8篇 |
1980年 | 13篇 |
1979年 | 5篇 |
1978年 | 3篇 |
1977年 | 7篇 |
1975年 | 1篇 |
1972年 | 2篇 |
排序方式: 共有10000条查询结果,搜索用时 0 毫秒
71.
采用经皮弧式椎间盘切除器械治疗L_5~S_1椎间盘突出症22例,21例成功。术后优良率为86.4%。该器械能够避开髂嵴阻挡进入L_5~S_1椎间隙,并增加椎间盘切除量,提高经皮L_5~S_1椎间盘切除成功率。定位正确是成功的关键。 相似文献
72.
作者选择乙基纤维素、聚乙烯醇等高分子材料制成涂膜剂,用大鼠皮进行双氯灭痛药膜的体外透皮速率测定。结果表明,氮酮与丙二醇可以促进药物渗透。不同的高分子材料可影响药物的扩散与释放,从而影响其透皮速率。与无膜无促透剂处方相比,药物在乙基纤维素中的透皮速率没有增加,在聚乙烯醇膜中的透皮速率有显著增加。 相似文献
73.
经内镜胆管引流术在肝门部恶性胆管梗阻中的应用及其评价 总被引:9,自引:2,他引:7
肝门部恶性肿瘤手术切除率极低,临床处理十分棘手。作者采用内镜胆管引流术治疗此类肿瘤288例次(肝门部胆管癌184例、胆囊癌23例、肝细胞癌侵犯肝门部胆管47例、其他转移性肿瘤34例),其中行内镜鼻胆管引流162例次、塑料内置管引流80例次、放置可膨式金属胆道支架46例、4例患者接受同期双内置管引流。引流总有效率为67.0%,其中效果满意者43.1%;40例患者术后1个月内发生胆管炎,发生率为13.8%,3例死亡;长期随访病例的平均存活期5.3个月。我们观察到治疗的效果与Bismuth分型有密切关系,如果全肝40%以上的胆系得到引流,黄疸有望消退;左、右两侧胆管同时引流可扩大引流范围,提高疗效;应合理选择三种内镜胆管引流方法并适时灵活转换才能获得满意的疗效。结论:对于肝门部肿瘤,内镜胆管引流术是一种安全有效的治疗手段,可作为首选的姑息性治疗。 相似文献
74.
Akihiko Usui Fumihiko Murakami Hideki Ooshima Yasuhiro Tomita Katsuhiko Yoshida Michiaki Hibi Mitsuo Kawamura Mitsuya Muras 《Artificial organs》1997,21(7):772-778
Abstract: Cardiopulmonary support (CPS) requires durability of the oxygenator. The life span of the oxygenator is affected by various clinical factors, including patient condition, perfusion condition, and equipment usage. Predictors for the durability of oxygenators were evaluated clinically in this study. Thirty-two patients, who had undergone CPS during the last 3 years in our institute were assigned to this study. Fifty oxygenators had been used (Capiox SX in 19, CB Maxima in 23, and AL-6000 in 8). Significant predictors for the durability of oxygenators were evaluated by nonparametric survival analysis and proportional hazards regression analysis. Univariate regression analysis revealed 6 significant predictors for the life span of oxygenators. These were the oxygenator type, type of centrifugal pump, acidosis with blood pH less than 7.35, base excess less than -5, blood glutamic-oxaloacetic transaminase (GOT) levels greater than 1,000 IU, and blood lactate dehydrogenase (LDH) levels greater than 3,000 IU. After multivariate analysis, there remained only 2 significant predictors. An oxygenator used with a noncoated CPS system (Capiox SX with Capiox EBS) proved to have a significantly shorter life span than one used with a heparin-coated system (CB Maxima or AL-6000 with CB BP-80) (hazards ratio, 3.588, p = 0.0065). Patient conditions, which revealed acidosis with less than -5 of base excess, significantly shortened the life of the oxygenator (hazards ratio, 3.595, p = 0.0188). 相似文献
75.
76.
Masao Tanaka Hiroyuki Konomi Hiroaki Matsunaga Kazunori Yokohata Naruhiro Utsunomiya Torahiko Takeda 《Journal of Hepato-Biliary-Pancreatic Surgery》1997,4(1):16-19
Technical improvements, such as mechanical lithotripsy, stenting or nasobiliary drainage, and wire-guided cannulation, have reduced the risk of complications in endoscopic sphincterotomy. To determine the extent of this reduction in risk, we assessed the medical records of 1352 patients with common bile duct stones in whom the procedure was conducted. Complications examined were: acute cholangitis and pancreatitis. Stone clearance was achieved in 1256 patients (92.8%), with an overall morbidity rate of 7.7% and a mortality rate of 0.15%. One hundred and forty-two patients had stones with a diameter greater than 20mm; 97 of these patients did not undergo lithotripsy. Cholangitis occurred in 10 of these 97 patients (10.3%), whereas, in the 45 patients who underwent lithotripsy, there were no cases of cholangitis (P=0.02). Stone removal was not immediately accomplished or attempted in 396 patients. In 82 of these patients in whom a stent or a nasobiliary drain was placed in the common bile duct, the incidence of cholangitis was 1.2%, significantly less (P=0.045) than the incidence of 6.4% in the other 314 patients given no stenting or nasobiliary drain. To overcome difficult cannulation, precut sphincterotomy was conducted in 134 patients and wireguided sphincterotomy, a recently introduced procedure, was conducted in 55 patients. When the precutting technique was used, the incidence of acute pancreatitis was significantly higher (8/134; 6.0%) than that in the patients in whom the standard procedure was conducted, i.e., neither the precut technique nor wire-guided ES was used (23/1218; 1.9%) (P=0.008). There were no cases of pancreatitis in the 55 patients in whom wire-guided sphincterotomy was performed, although the difference was not statistically significant because of the small number of patients (P=0.06). Based on these findings, we conclude that improved technologies have led to a significant reduction of complications in endoscopic sphincterotomy. 相似文献
77.
本文报道准分子激光冠脉成形术(ELCA)8例,均为男性,年龄平均61岁。心梗4例(2例有梗塞后心绞痛),4例仅表现为心绞痛。冠脉造影显示LAD狭窄6支,LCX狭窄4支,RCA狭窄4支。按ACC/AHA分型B型5例,C型3例。均用ELCA+PTCA。根据血管直径选用1.3mm(能量密度14.5mJ)和1.6mm(能量密度21.0mJ)激光导管,频率20Hz。1例导引钢丝未能通过狭窄,ELCA失败,另1例二次心梗,经旁路移植后仍有心绞痛发作,心功能较差,其ELCA虽获成功,但因病情严重死亡。8例中ELCA成功7例,手术成功6例。 相似文献
78.
回顾分析 65例脑脊液鼻漏病例。随访 3个月~ 1 0年 ,其中 2 6例经保守治疗痊愈 ,治愈率 40 %。 3 9例经保守治疗无效的患者 9例自动离院 ;行开颅手术修补 7例 ,其中 3例治愈 ;行鼻外入路修补术 3例 ,全部治愈 ;经鼻内镜修补术 2 0例 ,其中 1次手术治愈 1 9例 ,2次手术治愈 1例。经鼻内镜脑脊液鼻漏修补术的成功率为 1 0 0 % ,其中 1次修补成功率为 95 %。结果提示 :鼻内镜下脑脊液鼻漏修补术是外科治疗脑脊液鼻漏的首选术式 相似文献
79.
阻塞性黄疸:PTC下胆管钳夹活检的技术方法学研究 总被引:1,自引:0,他引:1
目的探索切实可行的胆管病理学检查新途径.资料与方法连续92例阻塞性黄疸患者接受经皮肝穿刺胆管造影(PTC)和经皮肝穿胆管引流(PTCD)治疗.PTCD过程中,影像监测下经皮经肝胆管穿刺,向胆管内引入活检钳对梗阻段钳夹活检,行组织病理学检查.统计学分析用χ2检验或Fisher确切概率计算法,以α=0.05作为检验水准.结果 92例钳夹活检患者90例成功获得组织块,技术成功率97.83%(90/92).钳夹活检敏感性为88.04%,63例胆管癌性恶性肿瘤钳夹活检敏感性较25例非胆管癌性恶性肿瘤高(93.65%比72.00%,P<0.05).结论PTC下胆管钳夹活检操作简单,创伤小,敏感性高,是一种值得推广的胆管病理学诊断新途径. 相似文献
80.
A report of a patient with an azygos lobe and an associated anomalous azygos vein covering the upper thoracic sympathetic chain. This anomaly poses a significant risk during the procedure of endoscopic thoracic sympathectomy. A chest X-ray is useful in detecting this anomaly and alerting the surgeon to potential problems. 相似文献