自然流产患者滋养细胞肝素表皮生长因子的表达及意义

目的　探讨自然流产患者滋养细胞肝素表皮生长因子 (HB EGF)的表达及其与滋养细胞增殖细胞核抗原 (PCNA)的关系。方法　选择自然流产患者和正常妊娠者各 2 0例 ,采用免疫组织化学法分析滋养细胞HB EGF和PCNA的表达。结果　HB EGF主要存在于细胞质 ,合体滋养层和细胞滋养层均有表达 ,部分流产滋养细胞不表达。自然流产患者滋养细胞HB EGF和PCNA的表达显著低于正常妊娠者 (P <0 .0 1) ,成正相关 (r =0 .4 5 4 ,P <0 .0 1)。结论　HB EGF的表达和滋养细胞增殖相关 ,HB EGF下降可能与自然流产的发生相关     

贺斯预防骨水泥所致低血压的临床探讨

目的:观察6%贺斯预防骨水泥所致低血压的效果。方法:30例人工股骨头置换病人随机分为两组:Ⅰ组为6%贺斯组(n=15);Ⅱ组为平衡盐组(n=15)。在填充骨水泥前分别输入6%贺斯及平衡盐500ml,分别测定入室(基础)、填充骨水泥前1min收缩压、填充骨水泥后5min最低收缩压,并观察心率变化。结果:Ⅰ组用骨水泥后最低收缩压明显高于Ⅱ组(P<0.01)。I组低血压发生率仅为13.3%,而Ⅱ组为60%。结论:在填充骨水泥前输注胶体能有效预防骨水泥所致的低血压。     

早孕妇女人工流产方式意向的临床调查研究

人工流产(简称人流)是各种避孕失败的主要补救措施,目前早孕妇女人流的主要方式有吸刮术与药物流产两种。本文通过对天津市黄河医院意外早孕妇女选择人流方式意向的临床调查研究,探讨现阶段该两种人流方式的可接受性,结果:1000例早孕妇女中选择药物流产(简称药流)者666例(66.6％),吸刮术者334例(33.4％)。本组选择人流方式的理由,其中519例(51.9％)认为药流痛苦少,占第一位,认为手术干脆而选择吸刮术的217例(21.7％),占第二位,其它依次为吸刮术费用低、药流不必手术、吸刮术流产完全、药流不需请假、吸刮术出血时间短、药流安全、吸刮术副作用少、药流保密。药流是近年来使用的流产新方法,本组研究资料及意向选择只反映现阶段早孕妇女的接受状况。     

Mifepristone-induced abortion and birth weight in the first subsequent pregnancy.

OBJECTIVES: To assess the effect of a medically induced abortion (MA) on birth weight in the first subsequent pregnancy. METHODS: Pregnant women who had had a MA, a surgical abortion (SA), or primigravidas with no history of abortion (NA), were recruited for a prospective cohort study between July 1998 and February 2001. The sample for the present analysis included 12995 singleton live births at term. RESULTS: The overall incidence rate of low birth weight (LBW) was 1.0%. The rates of LBW in the MA, SA, and NA groups were 1.0%, 0.9%, and 1.2, respectively. There were no significant differences in LBW rates between the MA and SA groups, neither between the MA and NA. Logistic regression analysis was used to estimate the effects of MA on birth weight, and we found no relationship between risk of LBW and MA. CONCLUSIONS: We did not find a statistically significant relationship between a history of one medically induced abortion and LBW for the first subsequent term pregnancy.     

Artificial bone of porous tricalcium phosphate ceramics and its preliminary clinical application

Summary The authors have prepared the artificial bone of porous tricalcium phosphate ceramics according to an appropriate formula and manufacturing technology. Physical and chemical testing shows that it possesses several distinguishing features: the communicating pores and macro/micropores; mean pore size, 380 μm (from 240 μm to 510 μm); porosity, 46.4 %; and compressive strength, 97.4 kg/cm². It consists of CaO (49.09 %) and P₂O₅ (48.84 %). The testing of its biocompatibility shows that it is devoid of systemic or local toxicity, and free of irritation or foreign body response in tissues, and it does not result in hemolysis or mutation. The new bone readily grows into its pores with direct contact to the implanted material. 11 cases of bone defects were treated with this artificial bone with satisfactory results.     

Computer-Assisted Design of an Implantable, Intrathoracic Artificial Lung

Abstract: A semiempirical mathematical model of convective oxygen transport is used to design a new, low pressure loss, implantable artificial lung that could be used as a bridge to lung transplantation in patients with advanced respiratory failure. The mass transfer and flow friction relations pertinent to the design of a cross–flow hollow fiber membrane lung are described. The artificial lung is designed to transfer over 200 ml/min of oxygen at blood flow rates up to 5 L/min. A compact design and a blood-side pressure loss of <15 mm Hg allows the device to be implanted in the left chest without the need for a prosthetic blood pump. Surgical implantation of the artificial lung would require the creation of inflow and outflow anastomoses. Oxygen would be supplied via an external source. Blood properties, operating conditions, and empirically determined mass transfer and flow properties are all specified and input into a computer program that numerically solves the design equations. Computer–generated values for the device frontal area, blood path length, and fiber surface area are thereby obtained. The use of this computer–assisted design minimizes the need for extensive trial–and–error testing of prototype devices. Results from in vitro tests of a prototype implantable lung indicate that the mathematical model we describe is an accurate and useful tool in the design of hollow fiber artificial lungs.     

79例人流术后支原体感染分析

７９例人流术后支原体感染分析陆海音，杨红英，周曾娣，张明秋，汤国民Ａｎａｌｙｓｉｓｏｆｋｙｃｏｐｌａｓｍａｓｉｎｆｅｃｔｉｏｎｓｉｎ７９ｗｏｍｅｎｗｉｔｈｉｎｄｕｃｅｉａｂｏｒｔｉｏｎＬｕＨａｉ－ｙｉｎ，ｙａｎｇＨｏｎｇ－ｙｉｎ，ＺｈｏｕＺｅｎｇ－ｄ...     

Transhemation of bovine and human hemoglobin polymers in a simulated circulatory system

All-Union Hematology Research Center, Moscow. (Presented by Academician of the Academy of Medical Sciences of the USSR A. I. Vorob'ev.) Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 112, No. 11, pp. 500–501, November, 1991.     

71例初产妇前置胎盘与人工流产相关性分析

目的:探讨初孕人工流产与再孕后前置胎盘发生率的相关性。方法:对1992年1月～2001年12月住院分娩的4046例初孕人工流产进行回顾分析,对影响前置胎盘发生率的因素进行x~2检验。结果:初产妇前置胎盘发生率为1.75％;人工流产次数越多,末次人工流产术后至本次妊娠时间间隔越短;人工流产术后有生殖道感染史者,前置胎盘发生率明显增高。结论:人工流产术是前置胎盘的高危因素,应加强育龄妇女的生殖健康宣传和教育,做到有计划受孕,减少非意愿妊娠的发生。     

人工肾的最新进展及临床应用

本介绍了人工肾的发展史、临床应用、选购和发展趋势。指出:随着高新技术和透析原理的发展，目前已从血液透析演变为血液净化，拓宽了其临床应用范围。采用组织工程、基因、细胞技术研制的生物人工肾，可望生产出易携带或可移植的生物人工肾，可完全替代肾功能，减少肾衰竭病人的死亡率，成为代肾发展史上的又一个里程碑。