抗旋钢板治疗股骨干骨折髓内针术后肥大型骨不连临床疗效分析

目的抗旋钢板治疗股骨干骨折骨髓内针术后肥大型骨不连的远期临床疗效分析。方法 2006年5月～2009年10月,15例股骨干髓内钉术后肥大型骨不愈合患者纳入本次研究,几乎所有内固定患者都发生了髓内钉的松动、拔出或折断。15例患者均采用有限切口切开骨折端应用小钢板加植骨治疗。结果 15例患者均获随访,平均随访时间15.8个月(12.0～16.0个月),均获得骨性愈合,平均愈合时间为3.2个月(2～6.2个月)。术后患者切口无感染、内固定松动或断裂、骨折畸形愈合等情况。结论采用微创小钢板、自体松质骨植骨技术是治疗交锁髓内针固定后肥大型骨不连的重要方法,因其满足了骨折端的力学稳定性、血供破坏小、技术成熟、并发症少,值得在临床推广。     

手术治疗四肢骨折后骨不连263例

目的回顾性分析四肢骨折后骨不连的发生原因及手术治疗结果。方法1996年5月～2005年8月共收治263例四肢骨折后骨不连患者。骨不连部位：股骨近端13例,股骨干57例,胫骨81例,肱骨51例,尺桡骨44例,锁骨5例,髋臼2例,舟骨3例,距骨4例,其它3例。本组患者全部采用手术治疗,其中交锁髓内钉固定157例,钢板螺钉固定72例,外固定架固定34例。植骨方法：单纯自体松质骨移植189例,自体松质骨混合其它材料移植57例,带血管蒂的游离骨瓣移植10例,自体骨髓移植4例,骨加压延长术3例。结果本组患者发生骨不连的主要原因为应力干扰和局部血供差,其次为感染、骨缺损及骨折复位不良、对位差、骨折间隙过大。242例患者获平均14．3个月(4～48个月)随访。242例患者均获骨性愈合,骨折愈合时间平均为5．3个月(3～18个月)。其中220例患者(90．9%)肢体功能优,无跛行等后遗症；22例患者(9．1%)遗留邻近关节活动受限、肢体短缩及跛行等许发症。结论骨不连的发生原因是多方面的,如果在治疗骨折时足够重视,多数骨不连可以避免。骨不连采用手术重新固定加自体植骨可获得良好疗效。     

分叉交锁髓内钉治疗肱骨干骨折不愈合的疗效分析

[目的]探讨分叉交锁髓内钉治疗肱骨干骨折不愈合的疗效。[方法]自2000年1月～2004年11月，用分叉交锁髓内钉治疗肱骨干骨折不愈合25例，均取出原内固定物，顺行插入分叉交锁髓内钉，术中同时行自体松质骨植骨。[结果]20例得到随访，随访时间为10～26个月，所有病例4～10个月均骨性愈合，无切口感染及骨髓炎的发生。[结论]分叉交锁髓内钉内固定能有效控制不良的剪应力，可提供牢靠固定，并发症少，是治疗肱骨干骨折不愈合的理想方法。     

带血管骨皮瓣移植治疗胫骨感染性骨不连

[目的]回顾总结带血管骨皮瓣移植治疗胫骨感染性骨不连的方法和疗效。[方法]从2002年8月~2004年8月,应用单边外固定架稳定骨折端,同时行带血管骨皮瓣移植治疗18例胫骨感染性骨不连,男15例,女3例,年龄18~51岁,平均34岁。清创后胫骨缺损3~8 cm,软组织缺损4 cm×3 cm~18 cm×9 cm。14例行带血管髂骨皮瓣移植修复,4例行带血管肩胛骨皮瓣移植修复,术后随访8~30个月,平均17个月。[结果]18例骨皮瓣全部成活,胫骨及软组织缺损Ⅰ期修复,外固定架固定牢固,获得骨性愈合时间8~13个月,平均10个月,3例出现外固定架钉道感染,1例发生取髂骨处疼痛。[结论]带血管骨皮瓣移植联合外固定架固定是治疗胫骨感染性骨不连行之有效的方法,Ⅰ期解决骨及软组织缺损的问题,促进骨的愈合。     

重建钢板与克氏针固定治疗锁骨骨不连的对比研究

目的比较重建钢板与克氏针固定治疗锁骨骨折骨不连的疗效. 方法 1991年9月～2002年1月采用两种材料固定治疗19例锁骨骨不连,男9例,女10例,年龄34～75岁.病程4～10个月,平均5.4个月.其中,重建钢板组9例,克氏针组10例.根据复位质量、骨愈合时间、肩关节功能、外观畸形、局部有无疼痛及体力劳动等情况评定疗效. 结果 19例均获随访6～23个月,平均11个月.骨愈合时间9～14周,平均11周.重建钢板组:优7例,良1例,可1例;克氏针组:优3例,良3例,可3例,差1例.重建钢板组优于克氏针组(P＜0.05). 结论重建钢板固定是治疗锁骨骨折骨不连的有效方法.     

Incredible position of broken sliding dynamic hip screw implant in the medial of thigh

We report a case with implant failure after nailing of an unstable pertrochanteric fracture with dynamic hip screw. The patient presented with a medial sided thigh pain at 5 years after the surgery. Plain radiographs showed nonunion of the fracture with distant migration of assembled hip screw and side plate to the subcutaneous area of the inner thigh.     

The missing effect of human recombinant Bone Morphogenetic Proteins BMP-2 and BMP-7 in surgical treatment of aseptic forearm nonunion

IntroductionIn this cohort study, the surgical revision concept of open compression plating and autologous bone grafting with and without additional application of BMP for treatment of aseptic ulna and/or radius shaft nonunion was evaluated. The purpose was to evaluate the clinical and radiological outcome, and to determine any difference in osseous healing, range of time between revision surgery and bone healing, and postoperative complications between the cohort groups.Patients and methodsBetween 01/2005 and 03/2015, a prospective, randomised, controlled cohort study was performed in a Level I Trauma Centre. Forty-nine patients were treated with the diagnosis of aseptic diaphyseal ulnar and/or radial shaft nonunion using compression plating and autologous bone grafting. Additional biological augmentation using BMP-2 or BMP-7 was performed in 24 patients. Clinical and radiological follow-up was performed six weeks, three and six months after revision surgery in accordance to the system by Anderson.ResultsThe study group consisted of 38 men and 11 women with a median age of 44 years (range 19–77). Twenty-four out of 49 patients obtained compression plating either with autologous iliac crest bone grafting (11/24 patients) or cancellous bone grafting (13/24 patients) and additional application of BMP-2 (4/24 patients) or BMP-7 (20/24 patients). The remaining 25 patients did not receive any additional application of BMP, but autologous bone grafting. The median follow-up was 15 months (range 6–54 months). Forty-six out of 49 nonunion healed within 12 months after revision surgery with a median time to union of six months. The clinical outcome, as assessed using the system by Anderson, as well as osseous healing, duration of time interval between revision surgery and bone healing, and postoperative complications did not demonstrate significant differences between the cohort groups.DiscussionAtrophic/oligotrophic forearm nonunion healed irrespective of additional application of BMP combined with autologous bone grafting. For successful treatment, radical resection of fibrous nonunion tissue and internal compression plate fixation is required with the aim of achieving high degree of rigid stability. Also, correction of angular deformities, restoration of length, and precise axial alignment of the distal radio-ulnar joint are mandatory prerequisites to successfully achieve bone healing.