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991.
Ömer Salt Mustafa Burak Sayhan Eren Duyar 《The American journal of emergency medicine》2018,36(12):2341.e1-2341.e2
Acute onset abdominal pain constitutes a significant proportion of emergency department visits, but only a small fraction of these cases are attributable to vascular pathologies (Bauersfeld, 1947 [1]). In this case, report, we present an incidental diagnosis of Spontaneous Isolated Superior Mesenteric Artery Dissection (SISMAD). A 69-year-old man was admitted to the emergency department complaining of fever, loss of appetite, vague epigastric pain, dysuria, and a productive cough for several days. A lower extremity venous Doppler ultrasound was performed, and a deep venous thrombosis (DVT) was identified in the left main femoral vein and in the proximal segment of the superficial vein. The patient also had no blood flow in the distal part of left external iliac vein. A contrast-enhanced computerized tomography angiography of the thorax and abdomen was performed to detect pulmonary embolism and the etiology of the abdominal pain. No pulmonary embolism was found; however, multiple metastatic nodules were identified in both lungs, as well as infiltration on the posterobasal field of the right lung, metastases on the liver, focal dilatation, and an intimal flap on the middle-distal part of the superior mesenteric artery (SMA) at 2?cm, with a segment that was compatible with isolated dissection. There was a contrast passage on the distal part of SMA, and no sign of bowel ischemia. 相似文献
992.
Gregory Gafni-Pappas Susanne D. DeMeester Michael A. Boyd Arun Ganti Adam M. Nicholson Jeremy Albright Juan Wu 《The American journal of emergency medicine》2018,36(10):1825-1831
Objective
The HAS-Choice pathway utilizes the HEART Score, an accelerated diagnostic protocol (ADP), and shared decision-making using a visual aid in the evaluation of chest pain patients. We seek to determine if our intervention can improve resource utilization in a community emergency department (ED) setting while maintaining safe patient care.Methods
This was a single-center prospective cohort study with historical that included ED patients ≥21 years old presenting with a primary complaint of chest pain in two time periods. The primary outcome was patient disposition. Secondary outcomes focused on 30-day ED bounce back and major adverse cardiac events (MACE). We used multivariate logistic regression to estimate the odds ratio (OR) and its 95% confidence interval (CI).Results
In the pre-implementation period, the unadjusted disposition to inpatient, observation and discharge was 6.5%, 49.1% and 44.4%, respectively, whereas in the post period, the disposition was 4.8%, 41.5% and 53.7%, respectively (chi-square p < 0.001). The adjusted odds of a patient being discharged was 40% higher (OR = 1.40; 95% CI, 1.30, 1.51; p < 0.001) in the post-implementation period. The adjusted odds of patient admission was 30% lower (OR = 0.70; 95% CI, 0.60, 0.82; p < 0.001) in the post-implementation period. The odds of 30-day ED bounce back did not statistically differ between the two periods. MACE rates were <1% in both periods, with a significant decrease in mortality in the post-implementation period.Conclusion
Our study suggests that implementation of a shared decision-making tool that integrates an ADP and the HEART score can safely decrease hospital admissions without an increase in MACE. 相似文献993.
Arasi Thangavelu Steven Rosenbaum Devi Thangavelu 《The Journal of emergency medicine》2018,54(6):892-897
Background
Cholecystitis is an inflammation of the gallbladder that most commonly occurs as a result of obstruction of the cystic duct by gallstones. The current standard of treatment for acute cholecystitis is cholecystectomy.Objective
Our goal was to discuss the benefits of and compare early laparoscopic cholecystectomy and delayed laparoscopic cholecystectomy in the treatment of acute cholecystitis.Materials and Methods
A Medline literature search was performed dating from January 1982 to July 2015. We limited the search to human studies written in English and using the keywords “Acute Cholecystitis,” early vs. delayed laparoscopic cholecystectomy, surgical management, and surgical complications.Results
There were 225 articles reviewed, of which 25 met criteria for selection. Our recommendations are based on these 25 articles.Conclusion
Early laparoscopic cholecystectomy is preferred over delayed, due to overall better quality of life, lower morbidity rates, and lower hospital cost. Ultimately, management of acute cholecystitis by emergency physicians should be made based on patient's clinical status and available resources in their particular hospital. 相似文献994.
Background
Acute proximal hamstring ruptures can be a diagnostic challenge in the emergency department. The revealing sign of large posterior thigh ecchymosis is typically not yet present; the physical examination is limited due to pain, radiographs can be unremarkable, and definitive testing with magnetic resonance imaging is not practical. These avulsions are often misdiagnosed as hamstring strains and treated conservatively. The diagnosis is made after failed treatment, often months after the injury. Surgical repair at that time can be technically challenging and higher risk due to tendon retraction and adhesion of the tendon stump to the sciatic nerve.Case Reports
The first case illustrates an example of how delay in diagnosis can occur in both emergency medicine and outpatient primary care settings. It also shows complications and morbidity potential for patients who warrant and do not receive timely surgical repair. The second case illustrates physical examination findings obtainable during the acute setting, and the use of point-of-care ultrasound (POCUS) in facilitating an expedited diagnosis and treatment plan.Why Should an Emergency Physician Be Aware of This?
Timely diagnosis of hamstring rupture is paramount to optimize patient outcomes for this serious injury. The best results are obtained with surgical repair within 3–6 weeks of injury. POCUS evaluation can aid significantly in the timely diagnosis of this injury. If the POCUS examination raises clinical concern for a proximal hamstring rupture, this may allow for earlier diagnosis and definitive treatment of proximal hamstring rupture. 相似文献995.
Sergey Motov Reuben Strayer Bryan D. Hayes Mark Reiter Steven Rosenbaum Melanie Richman Zachary Repanshek Scott Taylor Benjamin Friedman Gary Vilke Daniel Lasoff 《The Journal of emergency medicine》2018,54(5):731-736
Background
Pain is one of the most common reasons patients present to the emergency department (ED). Emergency physicians should be aware of the numerous opioid and nonopioid alternatives available for the treatment of pain.Objectives
To provide expert consensus guidelines for the safe and effective treatment of acute pain in the ED.Methods
Multiple independent literature searches using PubMed were performed regarding treatment of acute pain. A multidisciplinary panel of experts in Pharmacology and Emergency Medicine reviewed and discussed the literature to develop consensus guidelines.Recommendations
The guidelines provide resources for the safe use of opioids in the ED as well as pharmacological and nonpharmacological alternatives to opioid analgesia. Care should be tailored to the patient based on their specific acute painful condition and underlying risk factors and comorbidities.Conclusions
Analgesia in the ED should be provided in the most safe and judicious manner, with the goals of relieving acute pain while decreasing the risk of complications and opioid dependence. 相似文献996.
Mark Lidegaard Lars L. Andersen 《Journal of manipulative and physiological therapeutics》2018,41(6):483-487
Objective
The purpose of the study was to determine the association between trapezius muscle tenderness and tension-type headache among female office workers.Methods
Through a questionnaire survey, 256 female office workers with tension-type headaches reported the level of palpable tenderness (“no,” “some,” or “severe tenderness”) in the trapezius muscle. The number of days with headache (“0-7,” “8-14,” or “>14”), intensity (“low,” “moderate,” or “high”), duration of headache (“<8 hours per day,” “>8 hours per day,” and “all day”), and use of analgesic medications were reported. Odds ratio (OR) for tenderness in the trapezius muscle (“no/some” vs “severe tenderness”) as a function of days with headache, intensity of headache, duration of headache, and use of analgesic medications were calculated using a binary logistic regression controlling for age and body mass index.Results
After adjustments for confounders, a strong association was found between the level of trapezius muscle tenderness and intensity of headache (moderate intensity, OR 2.45; 95% confidence interval [CI] 1.08-5.54; high intensity, OR 7.51 [95% CI 2.65-21.29]) and days with headache (>14 days, OR 4.75 [95% CI 1.41-15.89]). No association was observed for duration of headache or use of analgesic medications.Conclusions
For the participants studied, there was a strong association between trapezius muscle tenderness and the level of intensity and the number of days with a headache among female office workers. No association was seen for duration of headaches or use of analgesic medications. 相似文献997.
Nikolas L. Krott Gunnar M. Bloyinski Erik Cattrysse 《Journal of manipulative and physiological therapeutics》2018,41(4):304-314
Objective
The purpose of this study was to investigate the influence of thoracic high-velocity low-amplitude thrust (HVLAT) manipulation on quantitative and qualitative 3-dimensional cervical spine kinematic patterns in a subgroup of patients with acute neck pain.Methods
Thirty patients with acute neck pain, aged 20 to 59, received a thoracic HVLAT manipulation. Three-dimensional kinematics of the cervical spine were registered pretreatment and posttreatment using an electromagnetic tracking system. Quantitative and qualitative parameters were calculated for axial rotation, lateral bending, and flexion-extension movement. Subjective pain ratings were measured with the visual analogue scale and the Neck Disability Index and were collected pretreatment and posttreatment.Results
After treatment, the range of motion of the main motion improved significantly for axial rotation (P = .034), lateral bending (P < .001), and flexion-extension (P = .031). Although for axial rotation as the main motion, the smoothness of the flexion-extension movement improved significantly after treatment (P = .036), the reverse was true for flexion-extension as the main motion. Visual analogue scale scores exhibited a statistically (P < .001) and clinically significant reduction of pain sensation. The mean change in Neck Disability Index scores only exhibited a statistically significant improvement 1 week after treatment.Conclusion
Thoracic HVLAT manipulation led to positive changes in quantitative and qualitative aspects of 3-dimensional cervical spine kinematics. Because of the 1-intervention group design, external factors influencing the healing process could not be eliminated. 相似文献998.
Simone Aparecida Penimpedo Calamita Daniela Aparecida Biasotto-Gonzalez Nívea Cristina De Melo Marco Antônio Fumagalli César Ferreira Amorim Cid André Fidelis de Paula Gomes Fabiano Politti 《Journal of manipulative and physiological therapeutics》2018,41(3):208-217
Objective
The objective of this study was to assess changes in upper trapezius myoelectric activity and pain in patients with nonspecific neck pain after a single session of acupuncture (ACP).Methods
A blinded randomized clinical trial was conducted. Fifteen patients with nonspecific neck pain and 15 healthy participants were enrolled in a randomized, single-blinded, crossover study. Each participant was subjected to a single session of ACP and sham acupuncture (SACP). The electromyography (EMG) signal of the upper trapezius muscle was recorded during different step contractions of shoulder elevation force (15%-30% maximal voluntary contraction) before and after ACP treatment.Results
Significant effects were confirmed after the treatment (ACP and SACP) for Numeric Rating Scale scores (F1,28 = 51.61; P < .0001) and pain area (F1,2 = 32.03; P < .0001). Significant decreases in the EMG amplitude were identified for the nonspecific neck pain group (NPG) (F1,112 = 26.82; P < .0001) and the healthy participant group (HPG) (F1,112 = 21.69; P < .0001) after ACP treatment. No differences were identified between the ACP and SACP treatment protocols for Numeric Rating Scale score (NPG: F1,28 = 0.95; P = .33), pain area (NPG: F1,28 = 1.97; P = .17), or EMG amplitude (NPG: F1,112 = 0.47; P = .49; HPG: F1,112 = 0.75; P = .38).Conclusion
The effect of ACP at acupoints triple energizer 5 and large intestine 11 triple energizer 5, or in close proximity, contributes to pain relief among patients with nonspecific neck pain. The electromyographic analysis indicated a greater resistance to muscle fatigue and decrease of activity of the upper trapezius muscle among healthy participants and patients with nonspecific neck pain. 相似文献999.
《武汉大学学报(医学版)》2015,36(1)
目的:探讨股骨近端空心钉锁定板内固定治疗股骨颈骨折的临床疗效。方法:股骨颈骨折行股骨近端空心钉锁定板内固定术13例,观察骨折愈合时间以及髋关节功能恢复情况。结果:术后13例骨折一期愈合,随访6-20个月,无退钉及断钉,1例股骨头坏死。Harris评分优8例,良4例,优良率92.3%。结论:股骨近端空心钉锁定板内固定治疗股骨颈骨折是有效的内固定方法,固定牢靠,便于患肢早期活动,改善髋关节功能,降低并发症,是较为理想的内固定方法。 相似文献
1000.
目的 观察消退素D2(RvD2)对非压迫性腰椎间盘突出症所致根性神经痛模型大鼠的影响。 方法 选取雄性Sprague-Dawley(SD)大鼠36只,按随机数字表法分为假手术组,模型组和RvD2组,每组大鼠12只。模型组和RvD2组均采用自体髓核组织填充法制作非压迫性腰椎间盘突出症模型,假手术组仅暴露相应手术部位,不作其它处理。造模成功后连续3d对假手术组和模型组均鞘内给予磷酸盐缓冲液(PBS)10μl,RvD2组则鞘内给予RvD2溶液10ng/10μl。于造模前1d和造模成功后连续7d观察3组大鼠术侧的50%缩足阈值(PWT),并于造模成功后第7天获取大鼠术侧L4至L6节段脊髓背角,采用蛋白质印迹法测定磷酸化的蛋白激酶B(p-AKT),蛋白激酶B(t-AKT),磷酸化的糖原合成激酶3β(p-GSK-3β)和糖原合成激酶3β(GSK-3β)的蛋白表达量,并用酶联免疫吸附试验测定肿瘤坏死因子α(TNF-α)、白介素-6(IL-6)、转化生长因子-β1(TGF-β1)和白介素-10(IL-10)的蛋白表达含量。 结果 造模成功后第1~7天,模型组和RvD2组大鼠50%PWT与假手术组同时间点比较,差异均有统计学意义(P<0.05);造模成功后第3~7天,RvD2组的50%PWT分别为(6.31±2.11)g、(7.37±1.58)g、(7.96±1.73)g、(8.46±1.55)g、(8.55±1.44)g,与模型组同时间点比较,差异均有统计学意义(P<0.05)。造模成功后第7天,模型组和RvD2组的p-AKT和p-GSK-3β蛋白阳性表达水平与假手术组比较,差异有统计学意义(P<0.05);且RvD2组的p-AKT和p-GSK-3β蛋白阳性表达水平与模型组比较,差异亦有统计学意义(P<0.05)。造模成功后第7天,模型组和RvD2组大鼠脊髓背角促炎细胞因子TNF-α和IL-6以及抗炎因子TGF-β1和IL-10的蛋白表达水平与假手术组比较,差异均有统计学意义(P<0.05); 且RvD2组促炎细胞因子TNF-α和IL-6以及抗炎因子TGF-β1和IL-10的蛋白表达水平与模型组比较,差异均有统计学意义(P<0.05)。 结论 RvD2可减轻非压迫性椎间盘突出大鼠的根性神经痛,其机制可能与抑制GSK-3β活性,下调促炎因子以及上调抗炎因子的蛋白表达水平相关。 相似文献