全文获取类型
收费全文 | 11057篇 |
免费 | 453篇 |
国内免费 | 448篇 |
专业分类
耳鼻咽喉 | 127篇 |
儿科学 | 69篇 |
妇产科学 | 50篇 |
基础医学 | 1046篇 |
口腔科学 | 179篇 |
临床医学 | 738篇 |
内科学 | 1216篇 |
皮肤病学 | 28篇 |
神经病学 | 398篇 |
特种医学 | 450篇 |
外科学 | 3499篇 |
综合类 | 2032篇 |
预防医学 | 582篇 |
眼科学 | 83篇 |
药学 | 784篇 |
8篇 | |
中国医学 | 457篇 |
肿瘤学 | 212篇 |
出版年
2024年 | 31篇 |
2023年 | 109篇 |
2022年 | 218篇 |
2021年 | 287篇 |
2020年 | 236篇 |
2019年 | 425篇 |
2018年 | 401篇 |
2017年 | 371篇 |
2016年 | 359篇 |
2015年 | 391篇 |
2014年 | 728篇 |
2013年 | 677篇 |
2012年 | 756篇 |
2011年 | 748篇 |
2010年 | 657篇 |
2009年 | 601篇 |
2008年 | 617篇 |
2007年 | 549篇 |
2006年 | 514篇 |
2005年 | 467篇 |
2004年 | 418篇 |
2003年 | 363篇 |
2002年 | 250篇 |
2001年 | 226篇 |
2000年 | 154篇 |
1999年 | 137篇 |
1998年 | 81篇 |
1997年 | 74篇 |
1996年 | 58篇 |
1995年 | 61篇 |
1994年 | 51篇 |
1993年 | 33篇 |
1992年 | 44篇 |
1991年 | 27篇 |
1990年 | 21篇 |
1988年 | 23篇 |
1987年 | 19篇 |
1985年 | 81篇 |
1984年 | 107篇 |
1983年 | 83篇 |
1982年 | 75篇 |
1981年 | 66篇 |
1980年 | 69篇 |
1979年 | 57篇 |
1978年 | 63篇 |
1977年 | 42篇 |
1976年 | 32篇 |
1975年 | 33篇 |
1974年 | 19篇 |
1973年 | 22篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
11.
G G Varela A López-Loredo J F García León 《JSLS, Journal of the Society of Laparoendoscopic Surgeons》2007,11(1):127-130
BACKGROUND AND OBJECTIVE: We present the case of a female patient 29 years of age with antecedents of laparoscopic laser ablation for endometriosis, laparoscopic appendectomy, and umbilical hernioplasty. METHODS: The patient was admitted to the hospital's emergency room for abdominal pain in the epigastrium, transfixing, irradiating to both upper quadrants and to the lumbar region, accompanied by nausea and gastrobiliary vomiting. Lipase determination was 170 mg/dL. Other laboratory findings were normal. Plain abdominal films on the patient's admission were normal, and computed tomography (CT) showed data compatible with acute pancreatitis. Without improvement during the patient's hospital stay, pain and vomiting increased in intensity and frequency. RESULTS: New abdominal x-rays revealed dilatation of small bowel loops. Management was begun for intestinal obstruction, with intravenous hydration and placement of a nasogastric tube without a good response. At 48 hours, a diagnostic laparoscopy was performed, revealing a 3-cm internal hernia in the left broad ligament in which a 20-cm segment of terminal ileum was encased. We performed liberation of the ileal segment and closed the hernial orifice by using the laparoscopic approach. CONCLUSION: The patient's evolution was excellent. 相似文献
12.
直视下经尿道内切开术治疗尿道狭窄 总被引:6,自引:0,他引:6
目的:探讨直视下经尿道内次切开术治疗尿道狭窄的有效性和安全性。方法:总结直视下经尿道内切开术治疗68例尿道狭窄和闭锁患者的疗效和经验,63例1次手术成功;3例行2次、2例行3次成功。结果:68例中,57例术后随访3~71个月,平均28.3个月,43例(75%)均排尿通畅;2例暂时性尿失禁者分别于术后3~6月内恢复。结论:直视下经尿道内切开术创伤小,并发症少,疗效确切,是尿道狭窄和闭锁的首选治疗方法。 相似文献
13.
14.
15.
K Kontou-Karakitsos J E Salvaggio K P Mathews 《The Journal of allergy and clinical immunology》1975,55(4):241-248
Based on sensitization following intranasal antigen administration, previous investigations have suggested greater absorption of allergens through the nasal mucous membranes of atopic than of nonatopic subjects. In this study mucosal absorption was assessed more directly by determining the capacity of allergens applied intranasally to elicit cutaneous Prausnitz-Küstner (P-K) reactions in nonatopic persons as compared with asymptomatic atopic subjects sensitive to other allergens. Two series of reaginic human serum dilutions were injected intracutaneously in recipients backs, and 48 hours later one series was challenged intracutaneously with test allergen. After the responses had been recorded, concentrated allergenic extract was sprayed into the nose and the second series of P-K sites observed for reactivity. Sometimes these P-K sites were rechallenged intracutaneously the following day to determine passive transfer neutralization. Two allergens were studied: bovine ribonuclease (RNase) and peanut extract. Two sera containing peanut reagins and one with RNase antibodies were each used in 10 to 11 atopic and 9 to 11 nonatopic recipients. The atopic group failed to show greater or more rapid absorption of either allergen through the nose based on the highest serum dilution reacting after nasal challenge. the speed of the reaction, the ratio of the titer by nasal challenge to the intracutaneous titer, or passive transfer neutralization. Controls showed that the results were not influenced by systemic absorption of allergen employed for intracutaneous tests. Drinking the amount of peanut extract applied intranasally did not elicit P-K reactions. 相似文献
16.
Kazuma Ohyashiki Mitsuo Oshimura Takayo Toyoda Nobuhiko Sakai Hisao Ito Kohtaro Yamamoto Akira Tonomura 《Cancer Genetics and Cytogenetics》1984,11(2):215-219
We encountered a 38-year-old Japanese male patient with chronic myelogenous leukemia (CML), whose bone marrow and peripheral blood cells during the chronic and blastic phases contained a complex Ph1 translocation and an extra Y chromosome [i.e., 47,XYY,t(9;22;13)(q34;q11;q14)]. A karyotypic analysis of PHA-stimulated lymphocytes showed the constitutional karyotype to be 47,XYY. Thus, it was considered that CML with a complex Ph1 translocation developed in an XYY male; such a case has not been reported, so far. A B-lymphocyte cell line with the complex Ph1 translocation was established by the procedure of Epstein-Barr virus transformation. The presence of the complex Ph1 translocation in the B-lymphocyte cell line suggests that some of the B lymphocytes in this patient originated from the CML clone. 相似文献
17.
从1972年11月到1994年3月,401例髋臼骨折病人中的99例经手术治疗并获随访,包括30例双柱骨折,13例横骨折伴后壁骨折,9例后壁骨折,9例后柱骨折,9例前往骨折伴前壁骨折,13例T形骨折和16例横骨折.平均随访时间为7年(2~14).外科手术入路的选择,后入路53次,髂腹股沟入路23次,延长的髂股骨入路11次,放射状入路9次和结合性入路6次.复位情况用X线平片来评判,解剖复位的有59例(59.6%),接近解剖复位(<2mm的错位)的有19例(19.2%).总结果用Harris Hip Score来评判,优秀的有53例(53.5%),良好的有25例(25.3%),一般的有14例(14.1%),差的有7例(7%).并发症中,有10例(53%)为感染,7例(37%)为静脉栓塞.这些结果表明,对于错位严重的髋臼骨折,切开复位内固定是一种可以选择的治疗方法. 相似文献
18.
Intraoperative internal mammary artery transit-time flow measurements: comparative evaluation of two surgical pedicle preparation techniques 总被引:1,自引:0,他引:1
B.H. Walpoth A. Mohadjer P. Gersbach R. Rogulenko B.N. Walpoth U. Althaus A. Mohadjer 《European journal of cardio-thoracic surgery》1996,10(12):1064-1070
Objects.
Myocardial revascularization is performed preferentially with internal mammary artery grafts. Pedicle preparation and pharmacologic vasodilatory treatment vary greatly. Objective measurements are difficult since peripheral and later coronary vascular resistance and possible competitive flow of the native bypassed coronary artery will influence the results significantly. Our objectives were: (1) measurement of internal mammary artery graft flow with the transit-time flow technique; (2) comparison of two surgical take-down techniques (skeletonizing vs standard pedicle preparation); (3) quantitation of transit-time flow compared to the free pedicle flow and (4) the vasodilatory effect of papaverine on internal mammary artery flow.Method.
Consecutive elective cases of coronary artery bypass grafting, performed by two surgeons using routinely either skeletonizing of the internal mammary artery (group A, n=10) or classical pedicle preparation technique (group B, n=10), were studied prospectively. Anesthesia, cardiopulmonary bypass and operative data were otherwise comparable; likewise, hemodynamic parameters showed no statistical differences between the two groups. Transit-time flow (CardioMed, Medi-Stim, Norway) was measured at the following time points: beginning (1) and end of take-down (2); after papaverine soaking: before (3) and on cardiopulmonary bypass (4); free flow into a beaker (5); after anastomosis; on (6) and off cardiopulmonary bypass (7).Results.
Measurement of mean flow showed the following results: (1) severe vasoconstruction of the internal mammary artery was detected in both groups regardless of the preparation technique (occurring earlier in group A); (2) papaverine soaking caused a moderate flow increase (up to 40%); (3) with corresponding cardiopulmonary bypass flow (4.4 vs 4.1 l/min in group B) a higher free flow in group A was evident (67.7 vs 50.7 ml/min); (4) after coronary grafting, transit-time flow showed no significant differences between the two groups and (5) using a 3 mm probe, a linear correlation was demonstrated between transit-time flow and simultaneously measured free flow (r=0.89).Conclusion.
Intraoperative transit-time flow measurement is a reliable method for assessing internal mammary artery and coronary artery bypass flow; considering the simple technical application, the procedure may be regarded as a valuable instrument of quality control. 相似文献19.
Kluger's Fixateur Interne proved to be an excellent tool not only in spinal trauma for repositioning of impacted fractures and transpedicular stabilization of the dorsal column but also in other forms of thoracic or lumbar instability.After spinal tumor excision from a dorsal approach and vertebral replacement with methylmethacrylate additional stability through dorsal fixation was achieved with this device.Spondylodiscitis, symptomatic spondylolisthesis, spinal instability from degenerative disc disease as well as nonunion following previous surgery could be cured using Kluger's internal fixation. Rare complications, i.e. from broken screws or rods (5%) caused no problems, but some patients required a second operation for readjustment of malpositioned screws which were causing pain or neurological deficit. 相似文献
20.
2002年某院老年内科死亡病例情况分析 总被引:2,自引:0,他引:2
[目的 ] 通过老年人内科疾病死亡情况的分析 ,为临床及时诊断、治疗和预防相关疾病提供证据。 [方法 ] 应用回顾性调查的方法 ,对 2 0 0 2年 1~ 12月在我院因内科疾病而死亡的 60周岁以上的病例进行分析。 [结果 ] 13 5例死亡病人中 ,13 3例 ( 98.5 % )患有基础疾病 ,其中 97例 ( 71.9% )为心脏疾病 ,64例 ( 4 7.4% )为高血压 ,49例 ( 3 6.3 % )为慢性阻塞性肺病。肺部感染为死亡的主要诱因 ,占 83 .7% ( 113 / 13 5 ) ;发生多器官衰竭 (MOFG)者占 44 % ( 60 / 13 5 ) ;发生衰竭的器官共 14 2例次 ,其中呼吸衰竭 89-4 5 6+1居首位 ,占 3 8.7% ( 5 5 / 14 2 )。 [结论 ] 我国老年人多患有慢性基础疾病 ,肺部感染是诱发病情加重导致死亡的最常见的因素 ,增强抵抗力 ,预防呼吸道感染是提高生活质量、延年益寿的关键 相似文献