首页 | 本学科首页   官方微博 | 高级检索  
文章检索
  按 检索   检索词:      
出版年份:   被引次数:   他引次数: 提示:输入*表示无穷大
  收费全文   5039篇
  免费   234篇
  国内免费   139篇
耳鼻咽喉   142篇
儿科学   34篇
妇产科学   11篇
基础医学   284篇
口腔科学   149篇
临床医学   527篇
内科学   265篇
皮肤病学   16篇
神经病学   606篇
特种医学   209篇
外科学   1259篇
综合类   898篇
现状与发展   1篇
预防医学   315篇
眼科学   148篇
药学   334篇
  6篇
中国医学   157篇
肿瘤学   51篇
  2024年   17篇
  2023年   74篇
  2022年   142篇
  2021年   200篇
  2020年   203篇
  2019年   154篇
  2018年   131篇
  2017年   153篇
  2016年   191篇
  2015年   152篇
  2014年   390篇
  2013年   327篇
  2012年   350篇
  2011年   356篇
  2010年   242篇
  2009年   273篇
  2008年   262篇
  2007年   255篇
  2006年   204篇
  2005年   218篇
  2004年   161篇
  2003年   127篇
  2002年   105篇
  2001年   71篇
  2000年   73篇
  1999年   66篇
  1998年   69篇
  1997年   52篇
  1996年   34篇
  1995年   46篇
  1994年   36篇
  1993年   38篇
  1992年   14篇
  1991年   27篇
  1990年   20篇
  1989年   29篇
  1988年   26篇
  1987年   11篇
  1986年   20篇
  1985年   18篇
  1984年   12篇
  1983年   5篇
  1982年   19篇
  1981年   10篇
  1980年   3篇
  1979年   5篇
  1978年   7篇
  1977年   5篇
  1974年   2篇
  1973年   3篇
排序方式: 共有5412条查询结果,搜索用时 0 毫秒
131.

PURPOSE

To compare the shear bond strength of various veneering materials to grade II commercially pure titanium (CP-Ti).

MATERIALS AND METHODS

Thirty specimens of CP-Ti disc with 9 mm diameter and 10 mm height were divided into three experimental groups. Each group was bonded to heat-polymerized acrylic resin (Lucitone 199), porcelain (Triceram), and indirect composite (Sinfony) with 7 mm diameter and 2 mm height. For the control group (n=10), Lucitone 199 were applied on type IV gold alloy castings. All samples were thermocycled for 5000 cycles in 5-55℃ water. The maximum shear bond strength (MPa) was measured with a Universal Testing Machine. After the shear bond strength test, the failure mode was assessed with an optic microscope and a scanning electron microscope. Statistical analysis was carried out with a Kruskal-Wallis Test and Mann-Whitney Test.

RESULTS

The mean shear bond strength and standard deviations for experimental groups were as follows: Ti-Lucitone 199 (12.11 ± 4.44 MPa); Ti-Triceram (11.09 ± 1.66 MPa); Ti-Sinfony (4.32 ± 0.64 MPa). All of these experimental groups showed lower shear bond strength than the control group (16.14 ± 1.89 MPa). However, there was no statistically significant difference between the Ti-Lucitone 199 group and the control group, and the Ti-Lucitone 199 group and the Ti-Triceram group. Most of the failure patterns in all experimental groups were adhesive failures.

CONCLUSION

The shear bond strength of veneering materials such as heat-polymerized acrylic resin, porcelain, and indirect composite to CP-Ti was compatible to that of heatpolymerized acrylic resin to cast gold alloy.  相似文献   
132.
133.
目的比较腰椎穿刺鞘内注射地塞米松与静脉推注地塞米松治疗显微血管减压术(MVD)术后无菌性脑膜炎(AM)的临床疗效。 方法选择自2015年1月至2020年1月于胜利油田中心医院神经外科就诊行MVD并诊断为AM的138例患者为研究对象,将患者分为对照组(68例)和观察组(70例)。对照组患者采用静脉推注地塞米松(10 mg/次)治疗,频率为按需给药;观察组患者采用腰穿放液联合鞘内注射地塞米松[60 μg/(kg·次)]治疗,频率为每日或隔日1次。比较2组患者治疗后的头痛及发热缓解情况、术后住院时间、治疗次数及激素不良反应情况。 结果治疗后8、72 h后,2组患者头痛、发热症状均明显好转,且观察组明显优于对照组,差异均有统计学意义(P<0.05);观察组患者的术后住院时间[(7.68±2.23)d]短于对照组[(12.76±2.37)d],治疗次数[(3.5±0.6)次]明显低于对照组[(6.8±0.9)次],差异具有统计学意义(P<0.05),2组患者均未见明显的激素不良反应。 结论腰穿放液联合鞘内注射地塞米松在治疗MVD术后AM患者中疗效确切,可有效改善患者头痛、发热等临床症状,减轻激素用量,缩短术后住院时间,具有重要的临床推广价值。  相似文献   
134.
目的 探讨脊柱均匀短缩脊髓轴性减压术(HSAD)对脊髓栓系综合征(TCS)合并脊柱侧凸的治疗效果。方法 回顾性纳入2015年4月至2018年1月在海军军医大学(第二军医大学)长征医院骨科因TCS合并脊柱侧凸行HSAD治疗的6例患者,记录手术时间、术中失血量、并发症等资料。并于术前、术后行尿动力学检查评估逼尿肌反射、括约肌功能、功能膀胱容量和最大尿流率。结果 男3例、女3例,年龄为7~23岁,平均年龄为(15.7±6.9)岁,平均随访时间为(28±9)个月。其中5例患者伴大小便失禁,3例伴足下垂,4例伴下肢肌力下降,1例存在腰痛,1例合并髋关节脱位。6例患者手术时间为180~320 min,平均(261±63)min;术中失血量为650~1 100 mL,平均(925±167)mL。1例腰痛患者术后腰痛症状完全缓解,4例伴下肢肌力下降患者术后下肢肌力均有改善。1例患者因术后未行尿动力学检查未予统计;其余5例患者于术前、术后均接受尿动力学检查,其中4例术前尿道外括约肌过动、1例失调,术后2例尿道外括约肌协调、1例改善、2例过动。术前、术后功能膀胱容量分别为195.0(127.5,233.5)mL、213.0(188.5,251.5)mL,差异无统计学意义(Z=-0.4,P=0.70)。术前最大尿流率、残余尿量分别为7.3(1.4,10.3)mL/s、130(106,200)mL,与术后[10.3(5.6,16.2)mL/s、30(6,174)mL]相比差异均有统计学意义(Z均=-2.0,P均=0.04)。5例患者术后膀胱逼尿肌肌力得到不同程度改善,最大尿流率增加,残余尿减少。结论 TCS合并脊柱侧凸可以通过HSAD一期手术治疗,该手术可同时缓解脊髓轴向张力、矫正脊柱畸形、恢复脊柱和脊髓的协调性。患者术后下肢症状和膀胱功能均得以有效改善,同时避免了脑脊液漏、出血多和神经功能恶化等并发症。  相似文献   
135.
Chlamydia spp. are obligate intracellular bacteria distributed globally, known to cause various forms of diseases in animals and humans. To date, there is limited information about the seroprevalence of Chlamydia and the risk factors associated with Chlamydia infection in dogs in the world. In the present study, a serological survey was undertaken to examine the seroprevalence and risk factors associated with dog chlamydiosis in Yunnan Province, southwestern China. A total of 591 dogs were sampled, antibodies to Chlamydia were determined by indirect hemagglutination assay (IHA). The overall seroprevalence was estimated at 17.6%. The risk factors associated with seroprevalence were determined by a multivariate logistic regression analysis. Gender and age of dogs were not significant in the logistic regression analysis (P > 0.05) and left out of the final model. Type and geographical origin of dogs were considered as main risk factors associated with Chlamydia infection, stray dogs (31.37%) were more than 16 times (OR = 16.167, 95% CI = 6.283–41.599, P < 0.01) at risk of acquiring the infection compared to the police dogs (7.62%), while pet dogs (14.41%) had a 3 times (OR = 2.968, 95% CI = 1.349–6.529, P = 0.007) higher risk. Positive dogs were found in 5 districts of Yunnan Province with prevalence ranging from 2.56% to 31.67% except Diqing (0/56). Dogs in Kunming (20.21%) had a 9 times higher risk of being seropositive compared to dogs in Lijiang (2.56%) (OR = 9.057, 95% CI = 1.211–67.714, P = 0.032), although no regional differences were found in other 4 administrative divisions compared to Lijiang (P > 0.05). Our study revealed a widespread and high prevalence of Chlamydia infection in dogs in Yunnan Province, southwestern China, with higher exposure risk in stray dogs and distinct geographical distribution. These findings suggest the potential importance of dogs in the transmission of zoonotic Chlamydia infection, and thus Chlamydia should be taken into consideration in diagnosing dog diseases.  相似文献   
136.
目的介绍个性化舌侧托槽的制作及其临床应用。方法预成舌侧托槽与个性化托槽底板铸造为一体。使用这种国产个性化舌侧托槽进行正畸治疗,其中安氏Ⅰ类68例,安氏Ⅱ类27例,安氏Ⅲ类9例。错[牙合]问题有:牙弓前突、开[牙合]、深覆[牙合]、反[牙合]、深覆盖、牙齿拥挤、牙齿阻生等。结果近百例舌侧正畸患者矫治效果良好,该方法对舌侧托槽的定位准确,除了可采取间接粘接以外,在二次粘接时可采取直接粘接。结论个性化舌侧托槽粘接精度优于传统的预成舌侧托槽粘接,牙齿排列更加整齐,能够得到满意的治疗效果。  相似文献   
137.
目的:评价磁共振体层血管成像(MRTA)对预测三叉神经痛患者微血管减压术(MVD)后疗效的价值.方法:277例行MVD的三叉神经痛患者手术前、后接受MRTA检查,由2名影像医师分别读取术前及术后NVC分级,术后疗效分为优、良和差3组,采用SPSS 13.0软件包中的x2检验确定术前NVC的压迫程度、术后NVC压迫程度和术后NVC的缓解度在3组的分布有无差异.结果:250例(90.2%)病例术后2年疗效为优,18例(6.5%)为良,8例(2.9%)为差,1例(04%)因术后颅内出血死亡.术前不同NVC分级的病例,术后疗效无显著差异(x2=5.542,P=-0.476);术后不同NVC分级(x2=18.693,P<0.05)和不同NVC缓解度(x2=11.484,P<0.05)的病例,术后疗效有显著差异.结论:MVD术后行MRTA检查,是预测术后疗效较为有效的方法之一,术后NVC分级越大和NVC缓解度越小的病例,MVD术后疼痛缓解不佳的可能性越高.  相似文献   
138.
Microvascular decompression is a very effective and relatively safe surgical modality in the treatment of hemifacial spasm. But rare debilitating complications have been reported such as cranial nerve dysfunctions. We have experienced a very rare case of unilateral soft palate palsy without the involvement of vocal cord following microvascular decompression. A 33-year-old female presented to our out-patient clinic with a history of left hemifacial spasm for 5 years. On postoperative 5th day, patient started to exhibit hoarsness with swallowing difficulty. Symptoms persisted despite rehabilitation. Various laboratory work up with magnetic resonance image showed no abnormal lesions. Two years after surgery patient showed complete recovery of unitaleral soft palate palsy. Various etiologies of unilateral soft palate palsy are reviewed as the treatment and prognosis differs greatly on the cause. Although rare, it is important to keep in mind that such complication could occur after microvascular decompression.  相似文献   
139.
We report a very rare case of cervical compressive myelopathy by an anomalous bilateral vertebral artery (VA) entering the spinal canal at the C1 level and compressing the spinal cord. A 70-year-old woman had been suffering from progressive gait disturbance. Magnetic resonance imaging revealed that a bilateral VA at the V4 segment had abnormal courses and caused compression to the high cervical cord. VA repositioning was performed by anchoring a suture between the artery and around the arachnoid membrane and dentate ligament, and then, microvascular decompression using a Teflon sponge was done between the VA and the spinal cord. The weakness in the patient improved in the lower extremity after the operation. Anomalous VA could be one of the rare causes of cervical compressive myelopathy. Additionally, an anchoring suture and microvascular decompression around the VA could be a sufficient and safe method to indirectly decompress the spinal canal.  相似文献   
140.
Peripheral nerve entrapment syndrome is a condition caused by the persistent application of pressure to a nerve. Symptoms include pain, numbness and tingling, and muscle weakness. The distribution of symptoms depends upon the nerve affected. This article discusses the aetiology, epidemiology and pathogenesis of peripheral nerve entrapment in the upper limb, and the principles of diagnosis and management. Common examples of nerve entrapment are described in greater depth.  相似文献   
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号