Effectiveness and Biomechanical Analysis of the Ortho-Bridge System on Femoral Fracture Healing: A Retrospective Analysis

BackgroundAmong the surgical methods for femoral fractures, the Ortho-Bridge System (OBS) appears to heal fractures via an uncommon process. We compared its effectiveness and biomechanical aspects to those of a locking compression plate (LCP) and explained the healing process demonstrated by the OBS.MethodsEleven femoral shaft fracture cases treated with OBS between July 2017 and May 2020 were retrospectively reviewed. Clinical and radiographic data were collected during regular postoperative follow-up visits and assessed via the Harris Hip Score and Knee Society Score. We performed biomechanical experiments of OBS. We simulated different fracture conditions and selected appropriate screw holes at the fracture’s far and near segments. The OBS module was placed according to the position of LCP’s locking hole at both ends of the fracture; then, a static three-point bending test was performed.ResultsAll patients had contralateral callus growth with secondary fracture healing. Healing time was 3–5 months with excellent hip and knee function. When the key screw distance was 22–34 mm, the OBS was significantly less stiff than the LCP (P < 0.05). The stiffness of LCP and OBS decreased significantly when the key screw distance was 49–82 mm, with the LCP being slightly stronger (P < 0.05).ConclusionsFemoral shaft fracture treatment with OBS demonstrated secondary healing. When the distance between the key screws was 20–40 mm, the elasticity was higher in OBS than in LCP, possibly producing axial micro-motion to stimulate callus formation and promote fracture healing, which differ from the plate’s primary healing process.     

Outcomes of Eight‐Plate Epiphysiodesis for Residual Clubfoot Deformities

ObjectiveThe outcome of congenital clubfoot treatment is still challenging if the feet deformities are not completely corrected. Here we explore a minimal invasive procedure with an eight‐plate implant to correct the residual forefoot adduction deformity after treatment of neglected or relapsed clubfoot.MethodsWe retrospectively reviewed patients with residual forefoot adduction deformity after clubfoot treatment between January 2013 and June 2016. The patients underwent temporary epiphysiodesis of the lateral column of the mid‐foot, which in detail, an eight‐plate was placed on each side of the calcaneocuboid joint. The foot deformities were recorded according to the weight‐bearing radiographic measurements including talo‐first metatarsal angle, calcaneo‐fifth metatarsal angle and medial‐to‐lateral column length.ResultsA total of 13 patients (20 feet) with an average age of 7.8 years old were located with an average duration of 40.8 months follow‐up (range, 28 to 54 months). The average talo‐first metatarsal angle improved from 28.3° (range, 19° to 47°) preoperatively to 8.3° (range, 3° to 18°) and the calcaneo‐fifth metatarsal angle improved from 29.1° (range, 19° to 40°) preoperatively to 8.4° (range, 0° to 21°) at final follow‐up. The mean ratio of the medial‐to‐lateral column length improved from 1.14 ± 0.06 to 1.55 ± 0.09 with statistical significance (t = 3.566; P < 0.001).ConclusionsEight‐plate epiphysiodesis is an easy and effective method for the correction of residual forefoot adduction deformity after clubfoot treatment in growing children without the need of osteotomy.     

锁定钢板加缝线技术与空心拉力螺钉技术固定肱骨大结节骨折效果比较

目的 通过比较锁定钢板加缝线技术与空心拉力螺钉固定肱骨大结节骨折的力学稳定性,探讨优化肱骨大结节骨折的内固定方式.方法 选择信阳市中医院2015年1月至2019年4月收治的肱骨大结节骨折患者52例,按照随机数字表法分为对照组22例和观察组30例,对照组采用半螺纹松质骨空心钉固定,观察组采用小型锁定钢板固定并辅助不可吸收...     

肿瘤术后下颌骨缺损的成型钛板即刻修复重建

目的研究下颌骨肿瘤切除后成型钛板即刻修复重建的手术方法和临床效果。方法根据患者下颌骨缺损范围及有无软组织缺损采用不同的修复方法,纯钛自动压缩重建固定板4例,纯钛下颌人工关节14例,并对不同缺损骨段修复重建后的面部形态和咬合关系进行比较。结果14例一侧下颌骨缺失成型钛板即刻重建取得良好的效果;而4例超越中线的下颌骨体缺失患者的效果不佳。结论成型钛板是修复一侧下颌骨缺失的良好的替代材料。     

A VAM-Based Equivalent Model for Triangular Honeycomb Sandwich Panels: Comparison with Numerical and Experimental Data

Due to their complex microstructures, the research on the static and dynamic behaviors of triangular honeycomb sandwich panels (triangular HSPs) is limited. In this study, the effective plate properties of triangular HSP was obtained by the homogenizing of the unit cell, and then the input to a VAM-based two-dimensional equivalent plate model (2D-EPM) to perform static and dynamic analyses. The accuracy of the proposed model for predicting the equivalent stiffness of the triangular HSP was verified by three-point bending experiments of 3D-printed specimens. Then, the static displacement, global buckling, and free vibrations predicted by 2D-EPM were verified with the results from three-dimensional finite element model simulations under various boundary conditions. The influences of structural parameters (including angle, core wall thickness, and cell side length of the unit cell) on the static and dynamic characteristics of triangular HSPs were also investigated, which can provide a useful tool for the modeling and evaluation of triangular HSPs under different conditions.     

MIPPO术对胫骨平台粉碎性骨折患者骨折愈合与关节功能恢复的影响

目的 探讨经皮微创锁定钢板内固定术(MIPPO术)对胫骨平台粉碎性骨折患者骨折愈合与关节功能恢复的影响.方法 选取2018年4月至2020年4月收治的84例胫骨平台粉碎性骨折患者,依照治疗方法 将其分为对照组(42例,常规切开复位内固定术)和研究组(42例,MIPPO术).比较两组的手术相关指标、膝关节功能恢复情况及康...     

HPLC法同时测定不同产地大花红景天中6种活性成分

目的对青藏高原不同产地大花红景天Rhodiola crenulata中没食子酸、红景天苷、酪醇、儿茶素、没食子酸乙酯、对香豆酸进行分析研究,建立定量分析方法,为其进一步利用提供依据。方法采用30%乙醇提取样品;Diamonsil C18色谱柱(250 mm×4.6 mm,5μm);以乙腈-0.3%磷酸溶液为流动相进行梯度洗脱;检测波长275 nm,柱温25℃。结果没食子酸、红景天苷、酪醇、儿茶素、没食子酸乙酯、对香豆酸分别在38.2~382.0 ng/m L(r=0.999 8)、301.0~3 010.0μg/m L(r=0.999 9)、19.8~198.0 ng/m L(r=0.999 6)、17.1~171.0 ng/m L(r=0.999 6)、4.5~45.0 ng/m L(r=0.999 8)、6.38~63.80 ng/m L(r=0.999 4)呈良好的线性关系,加样回收率均符合定量测定要求。结论该方法简便,快速,准确,可用于同时对青藏高原大花红景天中6种活性成分的测定。     

雷公藤多甙抑制EM患者腹腔巨噬细胞及相应细胞模型分泌TNF-α的实验研究

目的观察雷公藤多甙(TWP)对子宫内膜异位症(EM)患者腹腔巨噬细胞和小鼠腹腔活化巨噬细胞释放TNF-α的影响,以探讨TWP用于临床治疗EM的机制并建立细胞模型,为后续研究做准备。方法收集16例经腹腔镜检查确诊为EM患者腹腔液分离纯化巨噬细胞,并给予不同剂量的TWP进行共同孵育;同时分离纯化小鼠腹腔巨噬细胞,用脂多糖(LPS)激活以获得细胞模型,同样予TWP进行共同孵育。分别以间接MTT法和RT-PCR法在蛋白质水平和基因水平检测该药物影响激活状态巨噬细胞分泌TNF-α含量的变化。结果 EM患者腹腔液中TNF-α含量显著高于非EM妇女,在4～24 h后TWP(6.25～100μg/L)显著抑制了TNF-α的分泌。结论 TWP在蛋白质和基因水平均能有效抑制激活巨噬细胞分泌TNF-α。     

锁定钢板有限内固定结合中药外洗治疗Ⅲ型pilon骨折临床研究

目的:探讨锁定钢板有限内固定结合中药外洗治疗Ⅲ型Pilon骨折的疗效。方法:2009年6月-2011年5月,共收治41例Ⅲ型Pilon骨折患者,随机分为2组,治疗组21例采用锁定钢板有限内固定结合中药外洗,对照组20例采用常规的切开复位解剖钢板内固定,比较2组在手术时间、术后骨折复位影像学评价、早期并发症、远期并发症、踝关节功能恢复等情况。结果:41例患者全部获得骨性愈合,随访时间10～20个月,平均15.6个月。手术时间治疗组平均67min,对照组平均95min;术后骨折复位影像学评价治疗组关节面解剖复位率为85.71%,对照组关节解剖复位率为65.00%;早期并发症治疗组9.52%,对照组30.00%;远期术后畸形愈合、延迟愈合、创伤性关节炎及关节僵硬等并发症治疗组14.21%,对照组35.00%。据Mazur标准,本组治疗组优良率为90.48%,对照组优良率为70.00%。结论:锁定钢板有限内固定结合中药外洗较单纯的切开复位解剖钢板内固定治疗Ⅲ型Pilon骨折手术时间短,早、远期并发症少,踝关节功能恢复好。     

切开复位锁定接骨板固定治疗老年肱骨近端骨折的近期疗效

目的探讨切开复位锁定接骨板固定治疗老年肱骨近端骨折的近期疗效。方法回顾分析2007年5月～2011年1月间因移位性肱骨近端骨折接受锁定接骨板切开复位内同定治疗的98例（98肩）老年患者资料。术后进行临床及影像学随访,记录患者的骨折愈合时间、并发症情况。采用视觉模拟疼痛评分（VAS）、美国肩肘关节外科医师评分（ASES）对患者临床效果进行评估。结果所有患者均获随访,平均随访时间为16个月。1例因术后发生肱骨头坏死行肩关节置换,其余97例骨折均获得愈合,平均骨折愈合时间为4．5个月。6例出现一定程度肩关节周围肌肉挛缩。所有患者均未发生手术部位感染。平均VAS评分从术前（7．9±1．2）分降低到末次随访时的（1．9±0．8）分（P〈0．05）;平均ASES评分从术前的（13．7±9．6）分提高到末次随访时的（91．8±12．5）分（P〈0．05）。结论切开复位锁定接骨板同定治疗老年肱骨近端骨折的近期疗效满意,肱骨头坏死发生率低。