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111.
S. Friman H. Persson T. Scherstn J. Svanvik I. Karlberg 《Transplant international》1992,5(Z1):S187-S189
Acute rejection, occurring with a reported frequency of 50–70%, is still a dominating problem after liver transplantation. Medication with ursodeoxycholic acid (UDCA) has beneficial effects in different cholestatic conditions and has also been shown to reduce HLA class I antigen expression on hepatocytes in patients with PBC. Since August 1989 we have consecutively treated all patients with primary graft function with UDCA (n = 41). Patients transplanted in the first half of 1989 served as a control group (n = 8). All patients in this study were given sequential quadruple drug immunosuppression. The treatment group were given oral UDCA 10 mg/kg per day. During the first postoperative month, 17% of the UDCA-treated patients had an episode of acute rejection compared with 75% of the control patients (P < 0.01). Liver biochemistry tests 1 month postoperatively were significantly better in patients treated with UDCA. The results suggest that adjuvant treatment with UDCA reduces acute liver graft rejection. 相似文献
112.
113.
肾移植前后男性性生活状况比较 总被引:7,自引:5,他引:2
目的 :探讨肾移植前后男性性生活质量的变化。 方法 :将 86例男性肾移植病人分为低年龄组 (2 5~ 35岁 ,35例 )、中年龄组 (36~ 45岁 ,2 9例 )、高年龄组 (46~ 5 5岁 ,2 2例 ) 3组 ,分别调查病人患病前后、肾移植术后性生活能力、频率、性生活满意程度等性生活状况。 结果 :86例病人患病前均有性生活能力 ,患病后有性生活能力的 :低年龄组、中年龄组、高年龄组分别为 2 8.6 %,13.8和 9.1%。肾移植术后有性生活能力的 :低年龄组、中年龄组、高年龄组分别为 88.6 %、75 .9%和 6 3.6 %。 结论 :肾移植术后的性生活质量明显好于患病后 ,年龄越轻、恢复的越理想。 相似文献
114.
P. Berloco R. Pretagostini L. Poli M. Caricato A. Speziale D. Cozzi L. Gallinaro D. Alfani R. Cortesini 《Transplant international》1994,7(S1):314-317
Abstract The use of unrelated living donors in kidney transplantation is still controversial but many transplant centres have accepted this procedure. The main argument against this approach is usually an ethical one. Because of this, at our institution we accept biologically unrelated donors only if they have an emotional closeness to the recipient. From January 1983 to October 1993, out of 654 kidney transplantations we performed at our institution, 364 kidney allografts were from living donors. Of these living donors, 245 were first-degree relatives of the recipient (LRD) while 119 were unrelated (LURD); 100 cases were spouses-wife to husband in 76 cases and husband to wife in 24 cases Statistical analysis of the results (chisquare) revealed actuarial patient and graft survival rates of 89.8% and 86.8% at 1 year, 82.9% and 72.3% at 5 years and 12.3% and 60.3% at 9 years, respectively. In our series, the result of living donor kidney transplantation in this group were similar to those obtained in the LRD group, while they were significantly better than those from cadaver donors (P = 0.003). In conclusion, cadaver organs given the shortage of kidney transplantation between spouses may be a good alternative and can be performed successfully, providing a "gift of life" for both the patient and the family. 相似文献
115.
维生素C浸泡羊膜对眼碱烧伤后移植的可用性研究 总被引:2,自引:0,他引:2
目的探讨维生素C浸泡羊膜的特性和生物活性物质的改变,以求为维生素C浸泡羊膜在眼碱烧伤羊膜移植中的合理应用提供依据。方法维生素C浸泡新鲜羊膜、保存1月羊膜,分别观察其大体物理特性、光学显微镜观察组织特性、免疫组织化学检测细胞因子的表达。结果维生素C浸泡羊膜与非浸泡羊膜的大体物理特性及光学显微镜观察组织特性无显著差别、部分细胞因子的活性表达无改变。结论维生素C浸泡羊膜不改变羊膜的组织学特性及部分细胞因子的活性,可以方便、安全地应用眼碱烧伤的移植治疗。 相似文献
116.
前锯肌下部肌皮瓣移植的应用解剖 总被引:1,自引:1,他引:0
目的:为前锯肌下部肌皮瓣移植提供解剖学基础。方法:在25具(50侧)成人尸体标本上,对前锯肌下部的形态、血供和神经支配进行了应用解剖学观测。结果:前锯肌下部的血供主要来自胸背动脉的前锯肌支,外径1.3±0.2mm,伴行静脉外径1.5±0.2mm,长4.9±1.1cm;由胸长神经支配,其横径为1.7±0.4mm,神经干长7.7±1.4cm。结论:以胸背血管及前锯肌支为血管蒂和胸长神经为蒂可切取前锯肌下部12.0cm×9.0cm的肌皮瓣,修复较大创面或重建肌动力 相似文献
117.
目的:分析肾移植后免疫抑制剂对长期存活的影响,寻找移植后不同时间合适的免疫抑制用药方案及其用药剂量。 方法:对肾移植一年以上、肾功能正常的497例患者进行5年连续随访。根据移植后2、3、5年的不同免疫抑制用药将患者分为三联、二联、传统二联治疗三组。统计各组的排异发生率,排异和无排异患者免疫抑制用药的种类、剂量及CsA浓度,对排异患者追踪排异发生前12个月内的药物更动情况。 结果:肾移植后2、3、5 相似文献
118.
F. Debiais Dr. L. -G. Durand Z. Guo R. Guardo 《Medical & biological engineering & computing》1997,35(5):480-485
The basic parameters of the spectrogram, the Choi-Williams, and the Bessel distributions are adjusted to provide the best
time-frequency representations (TFRs) of the simulated murmur signals of mitral stenosis, mitral regurgitation, aortic stenosis,
aortic regurgitation, and of two musical murmurs. The initial adjustment of the parameters of each TFR technique is performed
by computing and minimising the relative averaged absolute error between the frequency contours at −3dB and −10dB of each
TFR of the simulated murmurs and those of the theoretical distribution of the same signals. The results show that the spectrogram
generally provides very good to excellent performance in representing the TFRs of stenotic and regurgitant murmurs. Improvements
provided by the Choi-Williams and the Bessel distributions are minor but not systematic for the two signal-to-noise ratios
tested (0 and 30 dB) and for the two frequency contours estimated. The Bessel and the Choi-Williams distributions provide
the best performance for the musical murmurs. The study shows that although a single technique cannot be optimal for all six
murmurs, the spectrogram using a Hamming window of 30 ms is an acceptable compromise to detect the six simutated heart murmurs. 相似文献
119.
JAIME VILA MARÍA NIEVES PÉREZ MARÍA DEL CARMEN FERNÁNDEZ JOAQUÍN PEGALAJAR MARÍA SÁNCHEZ 《Psychophysiology》1997,34(4):482-487
How cardiac components of the defense reaction are modulated by attentional factors related to sensory intake versus sensory rejection was examined. Forty-eight men participated in a test of the heart rate response to three presentations of an intense auditory stimulus while performing one of three attentional tasks during the 80 s following stimulus onset: (a) internal (rejection) task, (b) external (intake) task, and (c) no task. Results showed a potentiation of the defense response only under the external attention condition. We concluded that defensive reactions, far from provoking the rejection of the aversive stimulus, require allocation of attention to processing that stimulus in detail. 相似文献
120.
异体胸腺的解剖、组织学及吻合血管移植治疗晚期恶性骨肿瘤的研究 总被引:1,自引:0,他引:1
本文对20例20~36周引产死胎胸腺进行了解剖学,组织学观察,并应用吻合血管胎儿胸腺移植治疗晚期恶性原发及继发骨肿瘤12例。结果表明,胎儿胸腺的血供主要来自胸廓内动脉,其次为甲状腺下动脉和心包膈动脉胸腺支,7~8个月胎儿胸腺静脉血管壁较厚,适合作血管吻合,胸腺细胞发育成熟,组织结构正常,已有分泌胸腺素及转化免疫细胞的功能,在解剖学,组织学,免疫学方面均具备了良好的移植条件。12例接受吻合血管胎儿胸腺移植的晚期恶性骨肿瘤患者,其临床症状、体征、X线、免疫指数均有明显改善,患者生存6个月至37个月以上。 相似文献