GSS固定经椎弓根椎体内植骨治疗腰椎骨折

目的评价GSS固定经椎弓根椎体内植骨对于腰椎骨折患者的治疗效果。方法采用GSS固定经椎弓根椎体内植骨对62例患者进行治疗,观察治疗效果。结果与治疗前相比较,治疗后伤椎前缘高度显著升高,压缩角度和后凸Cobb角显著减低;神经功能平均分显著升高,差异均有统计学意义(P0.05),表明患者的神经功能得到了显著改善。结论 GSS固定经椎弓根椎体内植骨术治疗腰椎骨折不仅对于脊椎骨原形态的恢复有重要作用,还对恢复神经系统有促进作用。     

Hormonal action of relaxin-like gonad-stimulating substance (GSS) on starfish ovaries in growing and fully grown states

Gonad-stimulating substance (GSS) of starfish is the only known invertebrate peptide hormone responsible for final gamete maturation, rendering it functionally analogous to gonadotropins in vertebrates. Recently, we purified GSS from the radial nerves of the starfish Asterina pectinifera and identified the chemical structure as a relaxin-like peptide. This study examined the hormonal action of GSS on ovaries in the growing (stage IV) and fully grown states (stage V) of the starfish. The sensitivity of oocytes to 1-methyladenine (1-MeAde) as starfish maturation-inducing hormone was enhanced as oocytes enlarged in stage V. GSS-stimulated 1-MeAde production by ovarian follicle cells was also correlated with the size of oocytes. Although 1-MeAde production was observed in whole ovaries in stage V, GSS failed to induce 1-MeAde production in young ovaries (stage IV). This suggests that follicle cells in ovaries in a growing state (stage IV) are still unresponsive to the hormonal action of GSS. According to competitive experiments using radioiodinated and radioinert GSS, however, dissociation constant (K_d) values and the number of binding sites for GSS were mostly constant in the ovaries from stages IV to V. These results strongly suggest that GSS receptors are expressed in follicle cells of ovaries in the growing state. The failure of GSS to induce 1-MeAde production in young ovaries may be due to the uncoupling of signal transduction from the receptor to 1-MeAde biosynthesis in follicle cells.     

GSS固定椎管减压后外侧融合治疗老年女性腰椎管狭窄症

目的评价GSS（general spine system）固定椎管减压后外侧植骨融合治疗老年女性腰椎管狭窄症的疗效。方法对71例老年女性腰椎管狭窄症患者采用GSS固定椎管减压后外侧植骨融合治疗。结果所有病例经25~33个月,平均27个月随访,疗效优者41例,良20例,可9例,差1例,优良率85.7%。结论合适的GSS固定椎管减压后外侧植骨融合术治疗老年女性腰椎管狭窄症方法简单,疗效可靠。     

GSS在腰椎管狭窄症伴退变性滑脱手术中的应用

目的 探讨通用型脊柱内固定系统（GSS）在腰椎管狭窄症伴退变性滑脱患者手术中的应用价值。方法 对16例腰椎管狭窄症伴退变性滑脱患者行后路全椎板减压、GSS内固定加植骨融合术，其中多节段腰椎管狭窄11例，单节段腰椎管狭窄5例；L4滑脱9例，L5滑脱7例；Meyerding分类Ⅰ度滑脱14例，Ⅱ度滑脱2例。结果术后随访6—24个月，平均14个月，采用Stauffer—Coventry下腰椎术后疗效评定标准，优良率为88％，植骨融合率为100％，GSS无松动退出及断裂现象。结论在腰椎管狭窄症伴退变性滑脱后路全椎板减压术中，GSS系统可提供滑脱复位，恢复椎间隙高度及腰椎生理前凸，术后即刻稳定，植骨融合率高，是一种安全有效、操作简便的内固定系统。     

乡镇医院GSS脊柱椎弓根钉棒内固定治疗胸腰椎骨折12例报告

目的：总结乡镇医院应用GSS脊柱椎弓根钉棒内固定治疗胸腰椎骨折12例的经验。方法：采用GSS内固定系统治疗12例胸椎、腰椎骨折，随访、总结、分析手术疗效。结果：12例患者术后随访6～18个月，脊柱生理弯曲、椎体前缘高度恢复理想，疗效满意，有效率达90％。结论：GSS脊柱内固定系统结构简单、操作方便、复位确切、固定可靠，重建了脊柱的生理弯曲、椎体前缘高度恢复理想，是基层医院治疗胸椎、腰椎骨折的理想方法。     

GSS椎弓根系统加后路减压融合治疗退变性腰椎滑脱

目的:探讨后路应用通用型脊柱内固定系统(general spine system,GSS)复位固定,减压,椎体间植骨融合治疗退变性腰椎滑脱症临床效果.方法:将102例退变性腰椎滑脱症患者经保守治疗无效后采用GSS椎弓根螺钉系统内固定,后路减压融合手术治疗进行回顾性分析,其中Ⅰ度滑脱83例,Ⅱ度滑脱19例.比较手术前后临...