全文获取类型
收费全文 | 8529篇 |
免费 | 725篇 |
国内免费 | 164篇 |
专业分类
耳鼻咽喉 | 46篇 |
儿科学 | 173篇 |
妇产科学 | 70篇 |
基础医学 | 942篇 |
口腔科学 | 222篇 |
临床医学 | 1217篇 |
内科学 | 1514篇 |
皮肤病学 | 85篇 |
神经病学 | 619篇 |
特种医学 | 309篇 |
外科学 | 712篇 |
综合类 | 740篇 |
一般理论 | 10篇 |
预防医学 | 1501篇 |
眼科学 | 95篇 |
药学 | 614篇 |
3篇 | |
中国医学 | 299篇 |
肿瘤学 | 247篇 |
出版年
2024年 | 20篇 |
2023年 | 223篇 |
2022年 | 294篇 |
2021年 | 485篇 |
2020年 | 337篇 |
2019年 | 377篇 |
2018年 | 337篇 |
2017年 | 321篇 |
2016年 | 311篇 |
2015年 | 335篇 |
2014年 | 516篇 |
2013年 | 786篇 |
2012年 | 478篇 |
2011年 | 500篇 |
2010年 | 433篇 |
2009年 | 360篇 |
2008年 | 408篇 |
2007年 | 361篇 |
2006年 | 293篇 |
2005年 | 255篇 |
2004年 | 258篇 |
2003年 | 219篇 |
2002年 | 164篇 |
2001年 | 165篇 |
2000年 | 126篇 |
1999年 | 106篇 |
1998年 | 98篇 |
1997年 | 98篇 |
1996年 | 92篇 |
1995年 | 76篇 |
1994年 | 69篇 |
1993年 | 40篇 |
1992年 | 60篇 |
1991年 | 44篇 |
1990年 | 43篇 |
1989年 | 42篇 |
1988年 | 44篇 |
1987年 | 32篇 |
1986年 | 32篇 |
1985年 | 28篇 |
1984年 | 29篇 |
1983年 | 22篇 |
1982年 | 14篇 |
1981年 | 16篇 |
1980年 | 15篇 |
1979年 | 11篇 |
1978年 | 10篇 |
1976年 | 11篇 |
1975年 | 5篇 |
1974年 | 5篇 |
排序方式: 共有9418条查询结果,搜索用时 15 毫秒
11.
Evren Isci Halil Ibrahim Canter Abdullah Kecik 《European journal of plastic surgery》2007,30(1):45-46
Rabbits are the experimental animals of choice in many studies including flaps, wounds, and topical trials for new pharmacological
agents. Because the topical drugs and other materials used for dressing are irritating to the animal, they tend to remove
dressings, bandages, drapes, insensate flaps, and also topical drugs by scratching, licking, and biting if they are within
the reach of the animal. In this study, we report an easy to prepare, user-friendly, comfortable, and cheap dressing protector
called a dressing shield to prevent these problems. 相似文献
12.
Chronological changes in the complement system in sepsis 总被引:6,自引:0,他引:6
The time courses of serum complement levels and the severity of sepsis were compared in two groups of septic patients, one in which the patients survived (surviving group) and one in which they did not (nonsurviving group). The components of the complement system, namely, C3a, C4a, C5a, CH50, C3, C4, and C5, were measured at several points in time after the diagnosis of sepsis had been established. A 2-antibody radioimmunoassay was used to measure C3a, C4a, and C5a; the latex agglutination test was used to measure C3 and C4; nephelometry was used to measure C5; and Meyer's 50% hemolysis method was used to measure CH50. Following the diagnosis of sepsis, the levels of CH50, C3, and C4 were significantly lower in the nonsurviving than the surviving group, while the levels of C3a and C4a were significantly higher in the nonsurviving than the surviving group. The C5a levels were significantly higher in the nonsurviving than the surviving group, although no significant intergroup differences were subsequently noted. These results suggest that the serum levels of C3a, C4a, C5a, CH50, C3, and C4 could serve as indices of the severity of sepsis. Thus, monitoring the complement system may be useful for predicting the outcome of patients with sepsis. 相似文献
13.
T. Onishi T. Machida N. Iizuka K. Nakauchi H. Shirakawa F. Masuda S. Mochizuki H. Tsukamoto N. Harada 《Urological research》1990,18(5):313-318
Summary Utilizing two types of human renal carcinoma heterotransplanted in nude mice, we investigated the variations in hyperthermic effects (42.5°C for 30 min) caused by differences in tumor type with special reference to variations in tumor vascularity. In the hypovascular JRC1 strain, sporadic vascular dilation was observed throughout the tumors after heating. Destruction of tumor cells was observed mainly in the region of dilation. In the hypervascular JRC11 strain, homogenous vascular dilation was observed immediately after heating, mainly at the periphery of tumors. There was a decrease in the viability of cells in the center of the tumor. Therefore, the hypervascular tumors showed greater destruction mainly at the center where blood circulation was reduced. The range of necrosis was also greatly affected by the extent of vascular dilation caused by heating in hypovascular tumors. 相似文献
14.
The effects of running and meditation on beta-endorphin, corticotropin-releasing hormone and cortisol in plasma, and on mood 总被引:2,自引:0,他引:2
The relations between three hormones of the hypothalamic-pituitary-adrenocortical (HPA) axis, beta-endorphin (β-EP), corticotropin-releasing hormone (CRH) and cortisol, and mood change were examined in 11 elite runners and 12 highly trained meditators matched in age, sex, and personality. Despite metabolic differences between running and meditation, we predicted that mood change after these activities would be similar when associated with similar hormonal change. Compared to pre-test and control values, mood was elevated after both activities but not significantly different between the two groups at post-test. There were significant elevations of β-EP and CRH after running and of CRH after meditation, but no significant differences in CRH increases between groups. CRH was correlated with positive mood changes after running and meditation. Cortisol levels were generally high but erratic in both groups. We conclude that positive affect is associated with plasma CRH immunoreactivity which itself is significantly associated with circulating β-EP supporting a role for CRH in the release of β-EP. Increased CRH immunoreactivity following meditation indicates, however, that physical exercise is not an essential requirement for CRH release. 相似文献
15.
探讨老年人微小病变性(MC)特发性肾病综合征(PNS)的临床特征及预后。方法 观察成人MC性PNS118例,其中老年患者18例,占15.2%。结果 发现老年患者NS的临床表现与成年组相似;但血尿发病率较低,22%比38%;高血压和肾功能不全的发病率明显增高,38.9%比16%和33.3%比19%(P<0.01)。老年组对激素治疗的敏感性略差;但NS复发率明显减少,11.1%比43%。结论 尽管NS的复发和对激素依赖使治疗有一定困难,但激素、细胞毒性药物和环孢素A对于消除蛋白尿,延缓肾功能不全是有助的。 相似文献
16.
Tsuyoshi Takeda Hiroyuki Ishida Yukio Horiuchi Yasushi Nakao Yutaka Yabe 《Journal of orthopaedic science》1997,2(6):372-377
We examined radiographs of the elbows of the pitching arms of 79 professional baseball pitchers (mean age, 25.1 years; mean
duration of professional career, 4.7 years) and noted the frequency and size of spurs, bone fragments, and intra-articular
loose bodies according to site. The influence of duration of professional baseball career on these osteoarthritic changes
was also investigated. The olecranon tip was the most frequent site of spurs (62/79; 78.5%), and fragmentation of the spur
was detected in 17 joints. The frequency of spurs was also high at the medial margin of the olecranon, the tip of the coronoid
process, the medial margin of the sigmoid notch, the medial margin of the trochlea and the olecranon fossa. In 38 subjects,
spurs were observed at the distal portion of the radial notch of the ulna. However, few pitchers had osteoarthritic changes
in the humeral capitellum or radial head. Intra-articular loose bodies were detected in 4 of 79 joints (5.1%), and bone fragments
were present below the medial humeral epicondyle in 25 of 79 joints (31.6%). Osteoarthritic changes in the elbow joint appeared
to be attributable mainly to traction stress and impingement associated with extension and valgus strain. Significant osteoarthritic
changes were often found in professional pitchers whose careers exceeded 5 years. 相似文献
17.
Martin F. Ward Angie Titchen Clare Morrell Brendan McCormack Alison Kitson 《Journal of clinical nursing》1998,7(1):29-36
? The paper describes a multiproject practice development programme undertaken over a period of 1 year. ? The background and development of the programme are outlined, whilst attention is paid to the innovatory nature of the work, particularly the use of inductive, deductive and integrated approaches to both change implementation and project supervision. ? The programme was monitored throughout using different data sources and the paper uses evaluative material retrospectively to provide answers to organizational and professional difficulties which arose during the course of the programme. ? The authors conclude that the use of combinations of different models for practice development has potential, but requires careful supervision. ? They also recommend that those involved in practice development are made fully aware of its local or micropolitics, and develop strategies to deal with change before it occurs, not after it has taken place. 相似文献
18.
The morphological changes produced in the thyroid glands of albino rats following radiation with a 904 nm infrared laser were studied. Two different levels of radiation were applied: 46.8 J/cm2 and 140.4 J/cm2. Evaluation of the changes in the densities of the epithelial, colloidal and follicular volumes and of the activation index revealed that the laser beam produced changes in the thyroid parenchyma. It was observed that there was a direct relationship between the severity of the lesion and the radiation energy applied. 相似文献
19.
Background: The fabrication of dental prosthesis requires the transfer of interocclusal records from patient's mouth to semiadjustable articulators using different kinds of recording media. Any inaccuracy in these interocclusal records leads to occlusal errors in the final prosthesis. This study was conducted to evaluate the dimensional changes occurring in the interocclusal recording material over a given period of time and the material's resistance to compression during the cast mounting on the articulator. 相似文献
20.