首页 | 本学科首页   官方微博 | 高级检索  
文章检索
  按 检索   检索词:      
出版年份:   被引次数:   他引次数: 提示:输入*表示无穷大
  收费全文   362321篇
  免费   25297篇
  国内免费   7822篇
耳鼻咽喉   4171篇
儿科学   9665篇
妇产科学   6563篇
基础医学   29988篇
口腔科学   10107篇
临床医学   39397篇
内科学   43684篇
皮肤病学   4619篇
神经病学   19733篇
特种医学   9463篇
外国民族医学   31篇
外科学   43472篇
综合类   54030篇
现状与发展   13篇
一般理论   29篇
预防医学   35846篇
眼科学   5375篇
药学   31029篇
  420篇
中国医学   33888篇
肿瘤学   13917篇
  2024年   4083篇
  2023年   6972篇
  2022年   11043篇
  2021年   14699篇
  2020年   13812篇
  2019年   19195篇
  2018年   16750篇
  2017年   13646篇
  2016年   11014篇
  2015年   10267篇
  2014年   20984篇
  2013年   22494篇
  2012年   19019篇
  2011年   20559篇
  2010年   16602篇
  2009年   15272篇
  2008年   14850篇
  2007年   15255篇
  2006年   13390篇
  2005年   11558篇
  2004年   9594篇
  2003年   8340篇
  2002年   6541篇
  2001年   5915篇
  2000年   4834篇
  1999年   4228篇
  1998年   3439篇
  1997年   3285篇
  1996年   2799篇
  1995年   2704篇
  1994年   2572篇
  1993年   2055篇
  1992年   2081篇
  1991年   1773篇
  1990年   1575篇
  1989年   1415篇
  1988年   1349篇
  1985年   3813篇
  1984年   4831篇
  1983年   3375篇
  1982年   3833篇
  1981年   3571篇
  1980年   3172篇
  1979年   2922篇
  1978年   2548篇
  1977年   1918篇
  1976年   2164篇
  1975年   1640篇
  1974年   1432篇
  1973年   1280篇
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
101.
PurposeTo facilitate decision-making in authorship positions, the International Committee of Medical Journal Editor (ICMJE) developed a guideline that stipulates criteria authors should meet in order to merit authorship. Authors who did not meet these criteria and still enlisted as authors, are called ‘honorary’ authors. In this study, the prevalence and characteristics of honorary authorship (HA) is assessed in the field of Orthopedics and Sports Medicine.MethodsA survey was distributed among corresponding authors of articles published in 2019 in six Orthopedics-dedicated journals.Results479 of the 1392 approached authors responded, leading to a response rate of 34.4%. 91.6% of the respondents were aware of the ICMJE guidelines, whereas 67.8% were aware of the issue of HA. Overall, the prevalence of guideline-based HA was 41.9%, while the prevalence of self-perceived HA was 14.7%. Having a senior member automatically enlisted as author on the departments, was associated with a higher rate of guideline-based HA (OR 5.03) and self-perceived HA (OR 3.31).ConclusionsThe prevalence of HA in the field of Orthopedics and Sports Medicine is high, but comparable to other medical fields. Transparency in authorship decision-making is crucial to maintain liability in scientific articles.  相似文献   
102.
Background/ObjectiveOccurrence of post-dural puncture headache (PDPH) after diagnostic lumbar puncture (LP) for idiopathic intracranial hypertension (IIH) may seem very unlikely in clinical practice. Nevertheless, it has been suggested by several studies, mainly in sub-group analyses. We aimed to evaluate the prevalence of PDPH in an IIH population and determine any eventual predictive factors of PDPH occurrence.MethodsWe conducted a retrospective multiple-center observational study. All newly diagnosed IIH patients who met the International Classification of Headache Disorders (ICHD-3) or the Dandy modified criteria were included from three different French hospitals. They all underwent LP following the same process with the same type of needle. We recorded PDPH occurring within five days after LP, as defined by ICHD-3 criteria.ResultsSeventy-four IIH patients were recruited, of whom 23 (31%) presented with PDPH. Neither classical risk factors for PDPH such as body mass index, age or gender, nor cerebrospinal fluid opening pressure, or specific IIH features were associated with occurrence of PDPH.ConclusionPDPH can occur after LP in IIH patients. Clinicians should be aware of this possible event during the IIH diagnosis assessment and should not automatically reconsider IIH diagnosis. PDPH prevention using an atraumatic needle and dedicated PDPH treatment seem relevant in IIH patients.  相似文献   
103.
104.
BackgroundA leukocyte esterase (LE) test is inexpensive and provides real-time information about patients suspected of periprosthetic joint infections (PJIs). The 2018 International Consensus Meeting (ICM) recommends it as a diagnostic tool with a 2+ cutoff. There is still a lack of data revealing LE utility versus the ICM 2018 criteria for PJI.MethodsThis is a retrospective study of patients who underwent revision total hip and total knee arthroplasty at a single institution between March 2009 and December 2019. All patients underwent joint aspiration before the arthrotomy, and the LE strip test was performed on aspirated joint fluid. PJI was defined using the 2018 ICM criteria.ResultsAs per the 2018 ICM criteria, 78 patients were diagnosed with chronic PJI and 181 were not infected. An LE test with a cutoff of 1+ had a sensitivity of 0.744, a specificity of 0.906, a positive predictive value of 0.773, an accuracy of 0.825 (95% confidence interval 0.772-0.878), and a negative predictive value of 0.891. The positive likelihood ratio (LR+) was 7.917. Using an LE cutoff of 2 + had a sensitivity of 0.513, a specificity of 1.000, and an accuracy of 0.756 (95% confidence interval—0.812).ConclusionLE is a rapid and inexpensive test which can be performed at the bedside. Its performance is valuable as per ICM criteria. Based on the findings of this study and the given cohort, we suggest using the cutoff of LE1+ (result = negative or trace) as a point of care test to exclude infection, whereas LE at 2 + threshold has near absolute specificity for the diagnosis.  相似文献   
105.
AimsOrgan preservation, an important goal in the treatment of head and neck squamous cell carcinoma (HNSCC), may include induction chemotherapy and cisplatin with radiation therapy (CRT). To our knowledge, no reports have directly compared the impact of induction chemotherapy with that of CRT on health-related quality of life (HRQOL).Materials and methodsIn a phase II trial, we assessed the HRQOL of patients treated with induction chemotherapy followed by CRT. Eligible patients had stage III–IV HNSCC. HRQOL questionnaires were administered at baseline, the end of induction (EOI), the end of CRT (EOCRT) and after CRT. Functional Assessment of Cancer Therapy (FACT version 4) assessed HRQOL. We carried out a comparison of changes in HRQOL from baseline to EOI and from EOI to EOCRT. This trial is registered with ClinicalTrials.gov (NCT01566435).ResultsThirty patients were enrolled in the study. Most HRQOL questionnaires were completed (88%). The mean total FACT scores did not differ from baseline to EOI (general: 83.8 versus 79.1, P = 0.08; head and neck: 109.7 versus 105.8, P = 0.33; Total Outcome Index: 69.7 versus 62.3, P = 0.03; respectively, using P ≤ 0.01 to adjust for multiple simultaneous tests of differences). However, total FACT scores significantly worsened from EOI to EOCRT (79.1 versus 62.3, P = 0.01; 105.8 versus 74.2, P < 0.01; 62.3 versus 34.2, P = 0.01; respectively). Within domains, the head and neck cancer subscale score did not differ from baseline to EOI (median 28.5 versus 27.0, P = 0.69), but significantly worsened from EOI to EOCRT (27.0 versus 9.5, P < 0.01). Swallowing, oral pain and voice quality improved from baseline to EOI, but worsened from EOI to EOCRT. Physical and functional scores worsened from baseline to EOI and from EOI to EOCRT. The emotional well-being score improved from baseline to EOI but worsened from EOI to EOCRT.ConclusionsOverall, HRQOL did not significantly change from baseline to EOI but dramatically worsened from EOI to EOCRT.  相似文献   
106.
ABSTRACT

The present study investigated the concomitants of menopause-specific quality of life among premenopausal and postmenopausal women. Based on the Wilson and Cleary model of quality of life, this cross-sectional study recruited 329 women of age 40–65 years following operational convenience. The study was conducted in the office of the Korea Population, Health and Welfare Association (KPHWA) in Incheon, South Korea. Data collected on sociodemographic characteristics, social support, biological/physiological characteristics, the Pittsburgh Sleep Quality Index (PSQI-K), and self-rated health. Menopause-specific quality of life questionnaire (MENQOL) was used in this study. Hierarchical multiple linear regression analysis was performed. The study found that social support and self-rated health were negatively correlated with MENQOL in premenopausal women, while the income level and self-rated health were negatively associated with MENQOL in postmenopausal women. Sleep quality was positively correlated with MENQOL in both premenopausal and postmenopausal women. The study results indicate the need for tailored approaches based on menopausal status. Especially, social support may help improve the MENQOL of premenopausal women, while in postmenopausal women, improved sleep quality may enhance their menopause-specific quality of life.  相似文献   
107.
  1. Download : Download high-res image (230KB)
  2. Download : Download full-size image
  相似文献   
108.
109.
110.
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号