Cemento-ossifying fibroma of the left mandible: A case report

Ossifying fibroma is a type of benign fibro-osseous lesion. Most lesions affect the mandible region, particularly the molar and pre-molar areas. It predominantly affects females between the second to fourth decades of life. Larger ossifying fibroma tumors require more extensive resection. CASE SUMMARYA 39-year-old female complained of occasional pain and tumor enlargement on her left jaw for the 3 years prior to presentation. Intraoral examination revealed a firm swelling on her left lower gum. Extraoral examination revealed swelling on the left mandible body with no erythema and superficial ulcer. Computed tomography scan revealed a circular-shaped lesion on the patient’s left mandible body with a well-defined radiolucent border, sized 3.2 cm × 2.8 cm × 0.9 cm. The tumor was removed by marginal mandibulectomy. Biopsy from the resected tumor suggested cemento-ossifying fibroma (COF). CONCLUSIONCOF is often unnoticed, but this slow-growing tumor can cause significant symptoms regarding its distortion into adjacent structures.     

Radiología de las tumoraciones palpables en el paciente pediátrico. Parte 2

Palpable tumors in children are a common reason for consulting a radiologist. The origin of these lesions varies widely, and although they are common, classic radiology books do not cover some of them.This series of two articles aims to review the clinical and radiological characteristics of a selection of palpable tumors in children that radiologists need to be familiar with.     

Pedunculated,papillary giant cell fibroma in a pediatric patient: An immunohistochemical and in situ hybridization study

Giant cell fibroma (GCF), a benign fibrous proliferation, represents about 4.7% of all benign/reactive fibrous growths in the oral cavity. GCF preferentially affects Caucasians, with a peak incidence in the third decade of life, and slight female predilection. Clinically, small gingival nodules (about 1.0 cm in diameter) are often observed. Herein, we report a 5-year-old girl who was referred for evaluation of a pedunculated nodule on the gingiva, resembling a human papillomavirus (HPV)-associated papillary lesion clinically and microscopically. HPV was not detected by immunohistochemical and in situ hybridization analysis in the excised surgical specimen. Thus, the lesion was diagnosed as GCF. Papillary surface projections are rarely described in GCF, but it should be included in its clinicopathological spectrum, especially in pediatric patients.     

非骨化性纤维瘤1例诊治报告

患儿,男,11岁,因"左股骨上端骨折术后2周,复查X线片发现左股骨下端内侧骨破坏4月余"于2013年3月入院。入院时症见:左大腿外侧有手术瘢痕,左下肢活动无异常。查体:左股骨外侧大粗隆下可见一长约10 cm的纵形切口瘢痕,局部无环形压痛及纵轴叩击痛,左股骨下端内侧深压痛阳性,局部皮温如常。实验室检查:血常规、CRP、血清钙、血清磷、血沉、碱性磷酸酶均正常。X线片(图1a,1b)示:左股骨上端骨折钢板内固定术后,断端对位对线