全文获取类型
收费全文 | 2492篇 |
免费 | 165篇 |
国内免费 | 65篇 |
专业分类
耳鼻咽喉 | 39篇 |
儿科学 | 73篇 |
妇产科学 | 23篇 |
基础医学 | 263篇 |
口腔科学 | 393篇 |
临床医学 | 200篇 |
内科学 | 182篇 |
皮肤病学 | 72篇 |
神经病学 | 89篇 |
特种医学 | 184篇 |
外科学 | 800篇 |
综合类 | 188篇 |
预防医学 | 33篇 |
眼科学 | 42篇 |
药学 | 58篇 |
中国医学 | 27篇 |
肿瘤学 | 56篇 |
出版年
2024年 | 1篇 |
2023年 | 51篇 |
2022年 | 53篇 |
2021年 | 95篇 |
2020年 | 75篇 |
2019年 | 94篇 |
2018年 | 81篇 |
2017年 | 57篇 |
2016年 | 83篇 |
2015年 | 62篇 |
2014年 | 160篇 |
2013年 | 196篇 |
2012年 | 108篇 |
2011年 | 118篇 |
2010年 | 102篇 |
2009年 | 120篇 |
2008年 | 120篇 |
2007年 | 117篇 |
2006年 | 127篇 |
2005年 | 113篇 |
2004年 | 93篇 |
2003年 | 78篇 |
2002年 | 60篇 |
2001年 | 60篇 |
2000年 | 51篇 |
1999年 | 60篇 |
1998年 | 44篇 |
1997年 | 39篇 |
1996年 | 34篇 |
1995年 | 36篇 |
1994年 | 26篇 |
1993年 | 28篇 |
1992年 | 21篇 |
1991年 | 25篇 |
1990年 | 24篇 |
1989年 | 15篇 |
1988年 | 13篇 |
1987年 | 11篇 |
1986年 | 11篇 |
1985年 | 14篇 |
1984年 | 9篇 |
1983年 | 8篇 |
1982年 | 6篇 |
1981年 | 11篇 |
1980年 | 3篇 |
1979年 | 1篇 |
1978年 | 3篇 |
1977年 | 1篇 |
1976年 | 2篇 |
1975年 | 2篇 |
排序方式: 共有2722条查询结果,搜索用时 15 毫秒
51.
52.
Thoracoscopic anatomic segmentectomy is usually more complex than lobectomy. This video shows a 58-year-old female who suffered from limited bronchiectasis of the lingular segment of the left upper lung and a pericardial cyst on the same side. Both of these benign thoracic diseases can cause pleural adhesions. Repeated chronic inflammation contributes to hypervascularity and lymph node enlargement, making surgery more difficult. We used single-direction thoracoscopic segmentectomy via a three-port approach and successfully removed the lingula and pericardial cyst. 相似文献
53.
《Mayo Clinic proceedings. Mayo Clinic》2021,96(9):2342-2353
ObjectiveTo increase the likelihood of finding a causative genetic variant in patients with a focal segmental glomerulosclerosis (FSGS) lesion, clinical and histologic characteristics were analyzed.Patients and MethodsIndividuals 18 years and older with an FSGS lesion on kidney biopsy evaluated at Mayo Clinic from November 1, 1999, through October 31, 2019, were divided into 4 groups based on clinical and histologic characteristics: primary FSGS, secondary FSGS with known cause, secondary FSGS without known cause, and undetermined FSGS. A targeted gene panel and a customized gene panel retrieved from exome sequencing were performed.ResultsThe overall rate of detection of a monogenic cause was 42.9% (21/49). Individuals with undetermined FSGS had the highest rate of positivity (87.5%; 7/8) followed by secondary FSGS without an identifiable cause (61.5%; 8/13) and secondary FSGS with known cause (33.3%; 5/15). Four of 5 (80%) individuals in the latter group who had positive genetic testing results also had a family history of kidney disease. Univariate analysis showed that family history of kidney disease (odds ratio [OR], 13.8; 95% CI, 3.7 to 62.4; P<.001), absence of nephrotic syndrome (OR, 8.2; 95% CI, 1.9 to 58.1; P=.004), and female sex (OR, 5.1; 95% CI, 1.5 to 19.9; P=.01) were strong predictors of finding a causative genetic variant in the entire cohort. The most common variants were in the collagen genes (52.4%; 11/21), followed by the podocyte genes (38.1%; 8/21).ConclusionIn adults with FSGS lesions, proper selection of patients increases the rate of positive genetic testing significantly. The majority of individuals with undetermined FSGS in whom the clinical presentation and histologic parameters are discordant had a genetic diagnosis. 相似文献
54.
《The British journal of oral & maxillofacial surgery》2021,59(8):928-934
The aim of this study was to compare locking reconstruction plates with caudobuccally screwed custom mandibular reconstruction plates in bridging lateral mandibular segmental defects. The in vitro study was conducted on 13 polyurethane mandibles. A total of 7 mandibles with lateral segmental defects were bridged with locking reconstruction plates in group I, 6 mandibles with the same standard defect were bridged with caudobuccally screwed customised reconstruction plates in group II. Mean yield displacement, yield load, and displacement at 80 N (Newtons), 100 N, 200 N, 300 N loading were compared among the 2 groups. The mean (SD) displacement for Group I was 11.27 (3.6) mm, Group II was 21.08 (2.5) mm. Group II had significantly greater (p=0.0001) displacement when compared with Group I. The mean (SD) force before failure for Group I was 638.4 N (127.2), Group II was 1398. 3 N (162.7). Group II withstood significantly greater force than Group I (p=0.0001). The study reveals that the caudobuccally screwed custom reconstruction plates can significantly enhance yield load as preserving the preoperative shape of the face and mandible. 相似文献
55.
Satoru Kudose Dominick Santoriello Hanna Debiec Pietro A. Canetta Andrew S. Bomback M. Barry Stokes Ibrahim Batal Pierre Ronco Vivette D. D’Agati Glen S. Markowitz 《Kidney international》2021,99(1):247-255
- Download : Download high-res image (415KB)
- Download : Download full-size image
56.
R.W.H. Smits Ivo ten Hove E.A.C. Dronkers T.C. Bakker Schut H. Mast R.J. Baatenburg de Jong E.B. Wolvius G.J. Puppels S. Koljenović 《International journal of oral and maxillofacial surgery》2018,47(8):959-964
Resection margins are frequently studied in patients with oral squamous cell carcinoma and are accepted as a constant prognostic factor. While most evidence is based on soft tissue margins, reported data for bone resection margins are scarce. The aim of this retrospective study was to evaluate and determine the utility of surgical margins in bone resections for oral cavity squamous cell carcinoma (OCSCC). The status of bone resection margins and their impact on survival was investigated in patients who had undergone segmental mandibulectomy for OCSCC. Medical records were retrieved for the years 2000–2012; 127 patients were identified and included in the study. Tumour-positive bone resection margins were found in 21% of the patients. The 5-year overall survival was significantly lower in this group (P < 0.005). Therefore, there is a need for intraoperative feedback on the status of bone resection margins to enable immediate additional resection where necessary. Although the lack of intraoperative methods for the evaluation of bone tissue has been addressed by many authors, there is still no reliable method for widespread use. Future research should focus on an objective, accurate, and rapid method of intraoperative assessment for the entire bone resection margin to optimize patient outcomes. 相似文献
57.
《Néphrologie & thérapeutique》2018,14(7):501-506
Idiopathic nephrotic syndrome represents up to 30% of adult glomerulopathies. However, its prognosis according to remission, relapse and renal failure remains unchanged since the 80s and prediction remains difficult. Physiopathology of adult idiopathic nephrotic syndrome is complex and multifactorial, including immunologic and environmental factors and a putative permeability-circulating factor, still unknown. In this point of view, we propose to summarize actual knowledge about idiopathic minimal change disease and focal and segmental glomerulosclerosis physiopathology. 相似文献
58.
A systematic review of the survival and complication rates of resin‐bonded fixed dental prostheses after a mean observation period of at least 5 years
下载免费PDF全文
![点击此处可从《Clinical oral implants research》网站下载免费的PDF全文](/ch/ext_images/free.gif)
59.
《Renal failure》2013,35(7):726-729
AbstractAsk-Upmark kidney is a rare diagnosis of segmental hypoplasia in pediatric population clinically characterized by severe hypertension potentially treatable with partial to total nephrectomy. Although originally was described only as a congenital anomaly, recent data suggest to be caused by vesicoureteral reflux, either in utero or in early childhood and pyelonephritis. The case we reported indicates that Ask-Upmark kidney should be considered as potential cause of hypertension and renal failure both in children and adults. The renal biopsy is necessary for early diagnosis and may consent to normalize blood pressure with nephrectomy; however, if renal damage is severe and progressive with tubulointerstitial nephritis, surgical management is excluded and renal transplant should be considered. 相似文献
60.
Full‐arch implant fixed prostheses: a comparative study on the effect of connection type and impression technique on accuracy of fit
下载免费PDF全文
![点击此处可从《Clinical oral implants research》网站下载免费的PDF全文](/ch/ext_images/free.gif)