So-called "tension headache"--the response to a 5-HT uptake inhibitor: femoxetine

Sixteen patients with a headache resembling the so-called "tension headache" and a clear response to doxepin (demonstrated in a previous work) were given femoxetine, 400 mg p.d., and placebo in a cross-over, double-blind fashion. Only single blindness was kept in the last third of the study. Placebo and femoxetine tablets were each given for four weeks. Whereas there was a daily or practically daily occurring headache untreated, placebo was associated with a headache frequency of 92%. The corresponding figures for doxepin and femoxetine were 27% and 41%, respectively. Femoxetine led to transitory nausea and gastrointestinal discomfort, but in contrast to doxepin, no weight gain and only slight, if any, sedation. Most patients preferred femoxetine to doxepin. Femoxetine, an antidepressant phenylpiperidine derivative with predominant serotonin re-uptake inhibition (little effect on noradrenaline), thus seems to counteract so-called "tension headache".     

Impact of a Pilot School-Based Nutrition Intervention on Fruit and Vegetable Waste at School Lunches

ObjectiveTo determine the preliminary impact of the Brighter Bites nutrition intervention on decreasing fruit and vegetable (F&V) waste at school lunches among fourth- and fifth-grade children.MethodThis was a nonrandomized pre–post-controlled study in Houston and Dallas, TX. Two schools received the Brighter Bites intervention (n = 76), and 1 comparison school (n = 39), during the 2017-2018 school year. Brighter Bites is a 16-week school-based nutrition intervention providing weekly distribution of fresh F&V plus nutrition education. Main outcome measures were direct observation and weights to measure the number of F&V dishes selected at school lunches, amount of F&V wasted (gm), and related nutrient waste (4 time points/child). Mixed-effects linear regression analysis was used to determine change in F&V selection and waste over time.ResultsThere was a significant decrease over time in proportion of F&V selected among those in the comparison school, but not the intervention schools (P < .001). Compared with children in the comparison group, those receiving Brighter Bites showed a significant decrease in the amount of F&V wasted at each meal (P < .001) and per item (P < .05) at the end of both 8 and 16 weeks of intervention. There were significant decreases in waste of energy (kcal); dietary fiber (gm); vitamins B₁, B₃, and B₆ (mg); total folate (µg); and B₁₂ (µg) among those receiving Brighter Bites (P < .05).Conclusions and ImplicationsAlthough absolute food or nutrient changes were small even when significant, programs such as Brighter Bites may contribute to a healthy intake. Future studies are warranted that include a larger sample size with a stringent, cluster-randomized control trial design and consideration for other covariates.     

解剖钢板内固定治疗股骨粗隆间纵裂粉碎性骨折

目的：观察解剖型钢板治疗股骨粗隆间纵裂粉碎性骨折的疗效。方法：应用解剖型钢板对16例患者行内固定治疗。结果：随访9个月～2年,优11例,良4例,可1例。优良率为93．75％。结论：通过解剖钢板内固定治疗股骨粗隆间纵裂粉碎性骨折疗效满意。     

股骨骨折石膏固定术后腓总神经损伤的原因及处理

目的:总结股骨骨折石膏固定术后的腓总神经损伤的经验和教训。方法:回顾调查股骨骨折127例,对其中5例出现骨折石膏固定术后的腓总神经损伤的病例,分析损伤的原因及处理的临床疗效。效果:股骨骨折石膏固定术后腓总神经损伤常常产生于石膏固定后对腓总神经的牵拉、压迫。及时处理疗效尚为理想。结论:正确把握石膏固定方法,及时观察处理是解决股骨骨折石膏固定术后的腓总神经损伤的有效途径。     

Pilon钢板治疗Pilon骨折的临床观察

目的：探讨Pilon钢板治疗Pilon骨折的效果及临床应用价值。方法：对26例Pilon骨折患者行切开复位Pilon钢板内固定治疗,评价其治疗效果。结果：26例获得随访,平均随访时间（18.5±6.2）个月,骨折全部愈合。按Mazur等制定的评分系统,临床疗效优23例,良2例,可1例,优良率88.5%。结论：Pilon钢板治疗Pilon骨折疗效确切,是较理想的内固定材料,在临床应用上值得推广。     

小切口胆囊切除加胆总管探查一期缝合术并“J”形导管内引流用于胆总管结石的临床研究

目的:探讨小切口胆囊切除+胆总管探查,一期缝合,"J"形导管内引流术的临床疗效和适应指征。方法:2007年5月～2009年5月间我院为30例胆总管结石患者施行胆囊切除,胆总管切开,胆道镜取石。胆总管内J形导管引流术,总结该术的临床操作适应证及手术效果。结果:30例患者手术均获成功。术中取石顺利,术后无胆漏及残余结石。置入的J形导管30例脱落并排出体外。结论:小切口胆囊切除+胆总管探查一期缝合并"J"形导管内引流术对于胆总管结石的患者是安全可行的。且缩短病程,值得推广。     

锁定加压接骨板内固定在治疗小腿下端骨折中的应用

目的探讨使用锁定加压接骨板内固定(locked compressin plate LCP)治疗小腿下端骨折的临床运用及其疗效,为临床治疗提供依据。方法对2009年5月至2011年5月我院收治的72例小腿骨折使用锁定加压接骨板治疗患者,通过临床追踪随访,最后根据Johner—Wruhs评分、并发症、伤口愈合分级几方面进行评估,以判断该方法治疗小腿骨折的临床疗效。结果 72例患者术后经8～14个月随访,均获骨性愈合,平均愈合时间为12.6周,根据Johner-Wruhs评分:优49例,良18例,中4例,差1例,优良率为93.05%;除2例出现感染以外无其他并发症发生;70例患者伤口到甲级愈合,2例达乙级愈合。结论 LCP内固定治疗小腿下端骨折具有操作简单、创伤小、并发症少、疗效显著的特点,是目前骨折生物学固定的理想方法之一,值得临床推广。     

医学综述类文章常见问题分析

医学综述类文章是一种常见的文体。各医学期刊中综述类文章多存在文题命名、摘要和引言的撰写、中英文主题词规范化、内文即核心部分写作以及参考文献的正确性等方面问题。文中指出医学综述类文章中常见的问题,并从编辑的角度加以分析,以作为综述撰写人员写作水平提高之参考。     

链霉素月桂基硫酸钠亚碲酸钾琼脂平板(双洗平板)配制过程中的重要环节的探讨

目的:通过对使用不同容器,在不同温度下加入1%亚碲酸钾溶液和链霉素溶液配制成的链霉素月桂基硫酸钠亚碲酸钾琼脂平板(双洗平板)进行分析比较,重申在配制双洗平板过程中把握好几个关键环节的重要性.方法:先用玻璃容器配制成的双洗平板(不加入1%亚碲酸钾溶液和链霉素溶液)作空白对照平板,再分别用玻璃容器和金属容器(非不锈钢)盛放并煮沸双洗琼脂各两份,一份在高温80度左右加入1%亚碲酸钾溶液和链霉素溶液制成平板,另一份在低温55度左右加入1%亚碲酸钾溶液和链霉素溶液制成平板.结果:用玻璃容器配制的,且在55度左右加入1%亚碲酸钾溶液和链霉素溶液的双洗平板颜色最接近空白对照平板的颜色,其它均与空白对照平板颜色相差很大.结论:配制双洗平板时要使用玻璃容器,且须在低温55度左右加入1%亚碲酸钾溶液和链霉素溶液,才能确保双洗平板质量的可靠性.