Study of the oral carriage of Candida sp. in dental students and staff—Identification of Candida sp. and background survey

PurposeThe purpose of this study is to investigate the relationship between oral candidal carriage in able-bodied persons (dental students and staff) and health condition using a epidemiological method with questionnaire, and use the results for an educational campaign for the promotion of health.MethodsThe candidal carriage was examined by culture method using swabs from tongue surfaces. The identification of Candida spp. of the culture positive specimens was performed by a multiplex polymerase chain reaction method. Questionnaire items included age, gender, body mass index, pedometer use, oral conditions, regularity of hospital visits, medication, dental visits, oral care, exercise habits, alcohol habits, and smoking habits.ResultsA total 482 participants were surveyed over a period of two years, males: 269 (mean, 36 years); females: 213 (33 years). Oral candidal carriage was 18.3%. Candida albicans accounted for 80.7% of isolated Candida spp. After analysis using a stepwise method, three items (age, smoking habits, and exercise habits) were selected as the variables in the model. The adjusted odds ratios (95% confidence intervals) for the three model variables were 1.84 (1.10–3.08) for exercise habits, 1.93 (1.00–3.69) for smoking, and 0.96 (0.94–0.98) for age. Logistic regression analysis suggested an association between candidal carriage, exercise habits, and smoking.ConclusionsBecause lack of exercise, as well as smoking are well-known to be detrimental factors to the maintenance of good health, candidal carriers do not appear to be in a condition of good health. In other words, candidal carriage may be a health warning.     

An unusual cause of postfundoplication vomiting

This article demonstrates a previously unreported late occurring complication of fundoplication that leads to vomiting. A patient with cerebral palsy had the placement of a transesophageal suture, which, after ingestion of his family dogs' hair over time, created a significant-sized esophageal trichbezoar formed and caught around the suture. Upon removal of the bezoar via upper gastrointestinal endoscopy, the patient experienced immediate relief of his symptoms. This case should be considered in the appropriate clinical setting where the patient has demonstrated pica. An evaluation with contrast upper gastrointestinal studies proved to be critical in this case of postfundoplication vomiting.     

HPLC法测定小儿清肺八味丸中胆红素的含量

目的：建立蒙成药小儿清肺八味丸中胆红素的含量测定方法.方法：采用高效液相色谱法.色谱柱为Kromasil C18柱 （250 mm×4.6 mm,5 μm）;流动相为甲醇-三氯甲烷-1%磷酸溶液（70∶27∶3）;检测波长：450 nm;流速：1.0·min-1.结果：胆红素色谱峰峰形好,分离度符合要求,胆红素在1.0～30.0 μg·ml-1范围内与峰面积呈良好的线性关系（r=0.999 4）,平均加样回收率为101.1%,RSD为1.28%.结论：该方法简便、灵敏、准确、重复性好,可作为蒙成药小儿清肺八味丸中胆红素的含量测定方法.     

Gastric trichobezoar: An uncommon cause of epigastric pain: A case report

Trichobezoars are foreign and indigestible materials in the gastrointestinal tract and are usually found in psychiatric females, who often deny eating their own hair, but also at situations of gastric dysmotility and prior gastric surgery. Although rare, gastric trichobezoar should not be forgotten as a differential diagnosis in females presenting with vague epigastric pain. Its treatment well in time will prevent complications.