类保幼激素对三带喙库蚊幼期发育的影响

本文报告用亚致死剂量的 S—31183(类保幼激素)处理三带喙库蚊幼虫对其发育影响的研究,结果表明处理后蛹期死亡率明显高于幼虫期,并且与剂量大小有关。S—31183处理幼虫并不影响幼虫的发育时间,但可使幼虫化蛹时蜕皮受阻与羽化受到一定的抑制。     

“亚地克病”诊断标准探讨及修正建议

在新疆石河子市远郊缺碘地甲病区7～17岁儿童中取样,检测智力、精神运动功能、身高、体重和骨龄,发现精神运动发育障碍和骨龄落后的程度及发生频度明显高于非病区;而智力落后和体格发育落后两区无显著差异。根据这一发现认为在“亚地克病”诊断中,“精神运动发育测验”较“比内测验”更具有特异性和敏感性;建议在“出生、居住于缺碘地甲病区”前提下,将精神运动发育障碍和智力落后并列为主要条件。另根据地克病的分型原则,提出“亚地克病”的分型标准。     

脐血铅含量与婴儿神经行为发育的探讨

目的：了解广西地区儿童铅中毒状况，研究铅对婴儿神经发育的影响。方法：选择1020名婴儿，以脐血铅作为铅暴露示标，3月龄时在贝利（Bayley)婴儿发育表上以精神发育指数（MDI）和心理运动发育指数（PDI）为效应示标。结果：血铅≥0．48μmol/L的婴儿其MDI和PDI明显落后于相对低铅组，随着分界线的下移，两组间MDI和PDI差别渐趋缩小，当分界线为0.24μmol/L时，高、低铅组MDI和PDI已不存在统计学差异。结论：当血铅≥0.48μmol/L时，婴儿神经行为发育即可受到不利影响。     

通用型脊柱内固定系统椎弓根螺钉翻修作用的生物力学研究

目的测试自行设计的通用型脊柱内固定系统(generalspinesystem,GSS)椎弓根螺钉以及SOCON、TSRH和Diapason螺钉置入椎体的拔出力及旋入力矩,评价GSS螺钉的翻修作用。方法将36个正常成人腰椎椎体标本随机分为三组,每组12个椎体(24侧椎弓根)。各组标本每个椎体的每侧椎弓根均先拧入CCD螺钉(直径6.0mm,长45mm),行螺钉拔出试验,测试并记录螺钉的最大旋入力矩和最大轴向拔出力。然后各组标本每个椎体均随机选择一侧椎弓根经原钉道拧入GSS螺钉(直径6.5mm,长45mm);第一组另一侧拧入SOCON螺钉(直径7.0mm,长45mm),第二组另一侧拧入TSRH螺钉(直径7.0mm,长45mm),第三组另一侧拧入Diapason螺钉(直径6.7mm,长45mm)。分别测试螺钉最大旋入力矩及最大轴向拔出力。结果第一组GSS螺钉最大轴向拔出力为CCD螺钉的114%,SOCON螺钉为CCD螺钉的108%;GSS螺钉最大轴向拔出力大于SOCON螺钉,差异无显著性(P>0.05);GSS螺钉最大旋入力矩小于SOCON螺钉,差异无显著性(P>0.05)。第二组GSS螺钉最大轴向拔出力为CCD螺钉的127%,TSRH螺钉为CCD螺钉的64%;GSS螺钉最大轴向拔出力大于TSRH螺钉,差异有显著性(P<0.01);GSS螺钉最大旋入力矩大于TSRH螺钉,差异有显著性(P<0.01)。第三组GSS螺钉最大轴向拔出力为CCD螺钉的122%,Diapason螺钉为CCD螺钉的8     

Cranial nasal bone grafts

Reconstitution of the nasal scaffolding with maintainence of soft tissue proportions either following severe facial trauma or as a sequela to aesthetic rhinoplasty misadventures frequently is best achieved using the stability afforded by bone grafts. Split cranial bone grafts offer many advantages and may be the donor site of choice, and may even allow such surgery to be performed on an outpatient basis in some cases. The use of miniplate or screw osteosynthesis, now commonly accepted as a superior technique in craniomaxillofacial procedures, may simplify fixation of these calvarial nasal bone grafts with an apparent decrease in the risk of resorption.     

铁叶绿酸钠对小鼠行为发育毒性的实验研究

铁叶绿酸钠为叶绿素衍生物,研究表明铁叶绿酸钠治疗妊娠期缺铁性贫血,疗效显著。由于妊娠期用药可能对子代产生行为发育毒性,因此本文重点针对铁叶绿酸钠在动物围产期用药后,可能对子代动物的神经行为发育产生的毒性进行了测试,试验结果表明在高、中、低三种剂量下其对子代小鼠无明显行为发育毒性。     

齿槽裂修复方法的研究进展

目的 探讨齿槽裂修复治疗的目的、方法以及治疗时机的选择。方法 查阅1950年至2006年有关齿槽裂修复的文献，归纳文献中报道的不同方法，并评价其各自的优缺点。结果 齿槽裂修复的主要目的：关闭口鼻瘘；建立稳定、连续的上颌骨牙弓；为牙齿萌出提供基础；为上唇和鼻底提供稳定支架。主要治疗方法：植骨术；牵引成骨技术；组织工程骨和生长因子应用；引导骨再生技术。患者最佳的手术治疗时机是9～11岁时混合牙列期。结论 在9～11岁混合牙列期手术，以髂骨松质骨为移植材料被认为是修复齿槽裂的主要手段。牵引成骨技术、组织工程技术和引导骨再生技术，将是齿槽裂修复的新方向。     

中药对大鼠辐射损伤防护作用的实验研究

目的探讨中药当归、川芎、黄芪、丹参提取液对大鼠放射性骨髓损伤的防护作用.方法雄性SD大鼠60只,随机分为正常对照组、模型组、中药组,每组6只,在相同条件下饲养2周,模型组和中药组大鼠给予6.0 Gy 60Co γ射线一次性全身照射,继续饲养1周处死全部动物并取材.用骨髓细胞计数法计数骨髓有核细胞数,用Western blot法测定血管内皮生长因子（vascularendothelialgrowth factor,VEGF）、血小板衍生生长因子（ptatelet derived growth factor,PDGF）的蛋白含量.结果与正常对照组比较,模型组大鼠的骨髓有核细胞数、VEGF、PDGF蛋白含量明显减少（P＜0.01）,与模型组比较,中药组大鼠的骨髓有核细胞数、VEGF、PDGF蛋白含量明显增加（P＜0.01或P＜0.05）.结论中药当归、黄芪、川芎、丹参对大鼠放射性骨髓损伤有一定防护作用.     

Kindergarten children's representation and understanding of written number symbols

Two samples of kindergarten children's representation and understanding of written number symbols were examined in two time points in one academic year. About 85% of Chinese five year olds (mean = 5 years 10 months) were able to use conventional number symbols to represent the quantity of 30 or larger. At the end of the kindergarten year, 94% of Chinese six year olds (mean = 6 years 4 months) were able to use conventional number symbols to represent the quantity of 100 or larger. Some Chinese six year olds had problems in representing written addition and subtraction tasks. Children's ability to represent written number symbols, ability to represent written addition and subtraction formula and their performance on written addition and subtraction were closely related. The performance of children in a university-affiliated childcare center was better than that of the center serving working-class families in Time 1, but the performance reversed at the end of the kindergarten year.     

Myelination of the corpus callosum in the cat: time course, topography, and functional implications

The parameters of myelin development were ascertained in two specific regions of the corpus callosum in a series of cats aged 12 postnatal days through adult. The posteriormost portion of the splenium and the anterior-most portion of the genu were examined in cross section by using the electron microscope. Measurements were made to determine the age at which myelin first appeared, the number and distribution of myelinated fibers, the number and distribution of myelin lamellae, and cross-sectional area of ensheathed axons during development. The results indicate that myelination begins and ends earlier in the anterior region of the callosum. Measurements of myelin lamellae indicate similarities between anterior and posterior regions of the callosum, although development occurs earlier in the genu than in the splenium. No evidence was found for a sequence in the size of axons acquiring myelin sheaths, except that extremely small fibers are the last to begin myelinating. Myelination of the splenium of the corpus callosum begins at the very end of the behavioral and physiological critical period for the corpus callosum's role in visual functional development (Elberger: Behav. Brain Res. 11:223-231, '84; Elberger and Smith: Exp. Brain Res. 57:213-223, '85). Since myelination of a pathway is used as an index of functional reliability, this indicates that the basis for the callosal role in developing visual functions is probably not based on its physiological input to visual cortex.