收费全文 | 5409篇 |
免费 | 512篇 |
国内免费 | 138篇 |
耳鼻咽喉 | 109篇 |
儿科学 | 19篇 |
妇产科学 | 29篇 |
基础医学 | 634篇 |
口腔科学 | 352篇 |
临床医学 | 337篇 |
内科学 | 295篇 |
皮肤病学 | 19篇 |
神经病学 | 279篇 |
特种医学 | 492篇 |
外科学 | 1128篇 |
综合类 | 553篇 |
预防医学 | 125篇 |
眼科学 | 1338篇 |
药学 | 182篇 |
2篇 | |
中国医学 | 93篇 |
肿瘤学 | 73篇 |
2024年 | 20篇 |
2023年 | 121篇 |
2022年 | 233篇 |
2021年 | 322篇 |
2020年 | 269篇 |
2019年 | 246篇 |
2018年 | 289篇 |
2017年 | 225篇 |
2016年 | 251篇 |
2015年 | 209篇 |
2014年 | 360篇 |
2013年 | 385篇 |
2012年 | 296篇 |
2011年 | 312篇 |
2010年 | 285篇 |
2009年 | 254篇 |
2008年 | 239篇 |
2007年 | 254篇 |
2006年 | 204篇 |
2005年 | 178篇 |
2004年 | 136篇 |
2003年 | 105篇 |
2002年 | 113篇 |
2001年 | 97篇 |
2000年 | 79篇 |
1999年 | 70篇 |
1998年 | 67篇 |
1997年 | 50篇 |
1996年 | 48篇 |
1995年 | 31篇 |
1994年 | 24篇 |
1993年 | 28篇 |
1992年 | 25篇 |
1991年 | 29篇 |
1990年 | 23篇 |
1989年 | 20篇 |
1988年 | 22篇 |
1987年 | 15篇 |
1986年 | 9篇 |
1985年 | 19篇 |
1984年 | 20篇 |
1983年 | 9篇 |
1982年 | 12篇 |
1981年 | 19篇 |
1980年 | 10篇 |
1979年 | 7篇 |
1978年 | 8篇 |
1977年 | 4篇 |
1976年 | 3篇 |
1975年 | 3篇 |
Research design and methods: Demographic and clinical data were collected for each enrolled patient. Physical examination, anthropometric assessment, Psoriasis Area and Severity Index (PASI) assessment and body composition by BIA (single-frequency 50 kHz), were assessed at baseline and at 6 and 12 months of treatment.
Results: A significant decrease in body weight, compared to baseline, in BMI, Fat Mass at month 6 and a significant increase at month 12 for body cellular mass (BCM) and Phase Angle (PhA) were observed. In addition, a significant increase was found for intracellular water.
Conclusion: At baseline, psoriatic patients showed a lower BCM and a lower mean PhA score. During ustekinumab treatment, the mean PhA and BCM scores increased with an improvement in psoriatic disease. Thus, ustekinumab can be an effective drug for improving not only psoriasis but also the general clinical status of patients. 相似文献
Objective
To quantify the effects of initial hip angle and angular hip velocity settings of a lower-limb wearable robotic exoskeleton (WRE) on the balance control and mechanical energy requirements in patients with paraplegic spinal cord injuries (SCIs) during WRE-assisted sit-to-stand (STS).Design
Observational, cross-sectional study.Setting
A university hospital gait laboratory with an 8-camera motion analysis system, 3 forceplates, a pair of instrumented crutches, and a WRE.Participants
Patients (N=12) with paraplegic SCI.Interventions
Not applicable.Main Outcome Measures
The inclination angle (IA) of the body’s center of mass (COM) relative to the center of pressure (COP), and the rate of change of IA (RCIA) for balance control, and the mechanical energy and forward COM momentum before and after seat-off for energetics during WRE-assisted STS were compared between conditions with 2 initial hip angles (105° and 115°) and 3 initial hip angular velocities (800, 1000, 1200 rpm).Results
No interactions between the main factors (ie, initial hip angle vs angular velocity) were found for any of the calculated variables. Greater initial hip angle helped the patients with SCI move the body forward with increased COM momentum but reduced RCIA (P<.05). With increasing initial angular hip velocity, the IA and RCIA after seat-off (P<.05) increased linearly while total mechanical energy reduced linearly (P<.05).Conclusions
The current results suggest that a greater initial hip angle with smaller initial angular velocity may provide a favorable compromise between momentum transfer and balance of the body for people with SCI during WRE-assisted STS. The current data will be helpful for improving the design and clinical use of the WRE. 相似文献Background
Children with slipped capital femoral epiphysis (SCFE) are often seen by an array of medical professionals prior to diagnosis. Patients with mild slips, slips with knee pain, or bilateral slips can occasionally present a diagnostic challenge that increases the risk of a delay in diagnosis and associated complications.Objectives
This study introduces a new radiographic parameter, which we refer to as the S-sign, and analyzes its diagnostic utility on a frog-leg lateral radiograph.Methods
Twenty observers reviewed the radiographs from 35 patients with SCFE using Klein's line on anteroposterior pelvis radiographs and the S-sign on frog-leg lateral radiographs to diagnose an SCFE. Analysis included diagnostic outcomes and intraobserver and interobserver reliability.Results
The S-sign was more accurate at identifying an SCFE compared with Klein's line (92.4% vs. 79.2%, respectively). Sensitivity and specificity was greater for the S-sign compared with Klein's line (89.0% and 95.2% vs. 68.3% and 89.0%, respectively). A combination of the S-sign and Klein's line yielded a sensitivity of 96.5% and a specificity of 85.0%. The combination of tests was more diagnostic for an SCFE, compared with using the Klein's line, which was statistically significant (p < 0.001).Conclusions
With increased awareness of the S-sign and a usage of the combined test, clinicians can more reliably and accurately diagnose an SCFE. Clinicians are more likely to diagnose an SCFE using the combined test, compared with solely relying on Klein's line, which we found to be statistically significant. 相似文献![点击此处可从《Clinical & experimental ophthalmology》网站下载免费的PDF全文](/ch/ext_images/free.gif)