Accuracy analysis of computer-assisted surgery for femoral trochanteric fracture using a fluoroscopic navigation system: Stryker ADAPT®system

PurposeADAPT is a fluoroscopic computer-assisted surgery system which intraoperatively shows the distance from the tip of the screw to the surface of the femoral head, tip-to-head-surface distance (TSD), and the tip-apex distance (TAD) advocated by Baumgaertner et al. The study evaluated the accuracy of ADAPT.Patients and methodsA total of 55 patients operated with ADAPT between August 2016 and March 2017 were included as subjects. TSD and TAD were measured postoperatively using computed tomography (CT) and X-rays. The intraclass correlation coefficient (ICC) was checked in advance. The error was defined as the difference between postoperative and intraoperative measurement values of ADAPT. Summary statistics, root mean square errors (RMSEs), and correlations were evaluated.ResultsICC was 0.94 [95% CI: 0.90–0.96] in TSD and 0.99 [95% CI: 0.98–0.99] in TAD. The error was −0.35 mm (−1.83 mm to 1.12 mm) in TSD and +0.63 mm (−5.65 mm to 4.59 mm) in TAD. RMSE was 0.63 mm in TSD and 1.53 mm in TAD. Pearson’s correlation coefficient was 0.79 [95% CI: 0.66–0.87] in TSD and 0.83 [95% CI: 0.72–0.89] in TAD. There were no adverse events with ADAPT use.ConclusionADAPT is highly accurate and useful in guiding surgeons in properly positioning the screws.     

基于腹腔镜手术训练的眼动特征研究

在腹腔镜模拟训练过程中,研究不同训练模式下被测试者的注视策略,探索腹腔镜训练的新模式。被测试者被随机分为无指导组,视频学习组和专家指导组进行左右移环任务。利用Tobii X1 Light型眼动仪调用模拟训练箱中的摄像头,采集受试者的眼动数据。通过对数据处理分析,计算注视点个数,平均注视时间,注视时间百分比,扫描距离指标。与对照组相比,视频学习和专家指导模式下,任务完成时间降低23%,扫描距离缩短25%,注视点个数减少17%,平均注视时间没有显著差异。视频组和专家指导组之间无明显差异。结果表明不同学习模式下,被测试者的注视行为有明显差异。视频学习和专家指导下效果更好,可以用专家操作时的注视点视频指导初级训练者进行训练。     

单中心乳腺癌术后乳房重建的影响因素

背景与目的：乳腺癌手术方式的选择受到诸多因素影响，本研究旨在分析乳腺癌患者选择乳房重建手术的影响因素，重点探讨居住地距离与乳房重建的关系。方法：回顾性分析了1999年1月—2015年12月复旦大学附属肿瘤医院收治的因单侧或双侧0～Ⅱ期乳腺癌行全乳切除术的女性患者临床资料，分析居住地距离与乳房重建比例的关系。结果：非上海患者选择全乳切除术后乳房重建比例高于上海患者(6.1% vs 4.5%，P<0.001)。居住地距离影响乳房重建比例(P=0.035)。单因素分析显示，居住地距离越远，选择乳房重建手术比例越高，而年龄、体质量指数(body mass index，BMI)、TNM分期与乳房重建的选择呈负相关(P均<0.001)。多因素分析显示，年龄增长、BMI增加、TNM分期较晚是拒绝行乳房重建的独立影响因素(P均<0.001)，而居住地距离不是乳房重建的独立影响因素(P>0.05)，且与具体乳房重建方式无交互作用。年龄与居住地距离呈负相关(P<0.001)。结论：乳腺癌患者的居住地距离与乳房重建比例呈线性相关；年龄、BMI和疾病分期是影响乳房重建的主要因素。     

ECG beat classification based on discrete wavelet transformation and nearest neighbour classifier

Abstract

Myocardial infarction (MI) is a coronary artery disease acquired due to the lack of blood supply in one or more sections of the myocardium, resulting in necrosis in that region. It has different types based on the region of necrosis. In this paper, a statistical approach for classification of Anteroseptal MI (ASMI) is proposed. The first step of the method involves noise elimination and feature extraction from the Electrocardiogram (ECG) signals, using multi-resolution wavelet analysis and thresholding-based techniques. In the next step a classification scheme is developed using the nearest neighbour classification rule (NN rule). Both temporal and amplitude features relevant for automatic ASMI diagnosis are extracted from four chest leads v1–v4. The distance metric for NN classifier is calculated using both Euclidian distance and Mahalanobis distance. A relative comparison between these two techniques reveals that the later is superior to the former, as evident from the classification accuracy. The proposed method is tested and validated using the PTB diagnostic database. Classification accuracy for Mahalanobis distance and Euclidean distance-based NN rule are 95.14% and 81.83%, respectively.     

Genu varum and football participation: Does football participation affect lower extremity alignment in adolescents?

BackgroundGenu varum is one of the most common anatomical variations of knee alignment which is considered a risk factor for anterior knee pain and anterior cruciate ligament injury among football players. Considering that millions of children participate in high-level football training, the purpose of this study was to determine the genu varum development in adolescent football players and non-athlete peers. The hypothesis of this study was that genu varum incidence was higher in adolescent football players compared with non-athletic peers.MethodsThe design was a cross-sectional study. Two-hundred and thirty-seven male football players (FG) and aged-matched and anthropometrically similar non-athletes (CG) were recruited into the study. The quadriceps angle and intercondylar–intermalleolar distance were measured to evaluate the leg alignment. The distance between the medial edges of the condyles and malleoli was measured in millimeters using a digital caliper while angle measurements were performed using a photographic technique in a standing position. To analyze the variables, comparison, correlation and regression statistical tests were performed.ResultsThe intercondylar–intermalleolar distance and quadriceps angle values were significantly higher in FG than CG in all ages. In FG, a very strong correlation was found between number of training years and the intercondylar–intermalleolar distance. The prevalence of genu varum was markedly higher in FG than CG (~37% vs. 2%, respectively) based on intercondylar–intermalleolar distance.ConclusionThis study determined that the prevalence of genu varum and abnormal quadriceps angles in adolescent football players is significantly higher compared with their non-athletic peers.     

Geometrical Measurement of Central Tumor Location in cT1N0M0 NSCLC Predicts N1 but Not N2 Upstaging

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Hybrid Assistive Limb® for sporadic inclusion body myositis: A case series

We evaluated the efficacy of rehabilitation therapy with Hybrid Assistive Limb® (HAL; hereafter HAL therapy) in three patients diagnosed with sporadic inclusion body myositis (sIBM) who were hospitalized to undergo HAL therapy. Among them, one patient participated in eight courses and the other two in two courses of HAL therapy between 2017 and 2020. We determined the mean rate of improvement in two-minute walking distance and 6 m walking speed at the time of hospital discharge. After HAL therapy, we confirmed the patients’ desire to continue the use of HAL. In one patient, we observed improvements of 146.0% and 120.0% in two-minute walk and 6 m walking speed, respectively, after the first course of HAL therapy; these values are 133.7% and 130% after the eighth course of HAL therapy. These values exceeded 90% in the other two patients after the second course of HAL therapy. HAL therapy maintained both quantity and quality of ambulation and showed positive psychological effects on patient conditions because it reduces exercise load and facilitates safety. While HAL therapy might be effective in maintaining and improving ambulation in patients with sIBM, we should consider to discontinue HAL therapy as it increased risk of falling.