聚丙烯酰胺水凝胶注射隆乳应用体会

目的 探索准确的乳腺后间隙注射聚丙烯酰胺水凝胶隆乳的方法，减少并发症的发生。方法 采用长钝针穿刺，进入乳腺后间隙，一点注射麻醉药及水凝胶。结果 为869例患者行聚丙烯酰胺水凝胶注射隆乳，渴意率达98．3％。结论 准确的注射层次和及时正确的处理并发症，是聚丙烯酰胺水凝胶注射隆乳术的成功保证。     

牙周组织病

bFGF和rhBMP对牙周膜细胞胶原酶水平的影响，龈上牙结石附着面和游离面晶体构型的扫描电镜观察，米诺环素对人牙周韧带绷胞矿化能力的影响，米诺环素软膏局部治疗慢性牙周炎的峰床疗效[编者按]     

肾移植前后常染色体显性遗传多囊肾病囊液中层粘蛋白水平的比较及意义

常染色体显性遗传性多囊肾病(ADPKD)是一种系统性疾病，约占终末期肾病的8％～12％，一部分患者需肾脏移植。多囊肾囊泡基底膜的降解产物层粘蛋白(LN)、Ⅳ型胶原等存在于囊液中，是引起上皮细胞增生、分化的重要因素，目前根据LN的含量评估多囊肾的增生态势已有充分的依据。本研究通过测定肾移植前后囊液中的LN含量，     

重组2型腺相关病毒-转化生长因子β3对实验性肝纤维化大鼠肝脏组织病理学和Ⅰ型胶原表达的影响

Objective To investgate the effects of TGF β 3 on rat hepatic fibrosis. Methods The TGF β 3 cDNA was cloned into rAAV2 vector. Rats were randomly divided into four groups: normal control group, model group, negative control group and TGF β 3 group. Hepatic fibrosis was induced by hypodermic injection of 40% CCI4. Recombinant AAV2-TGF β 3 viral particles were injected via the vena caudalis one week before CCh treatment. Rats were executed 8 weeks after CCI4 treatment, global histological change was observed after HE staining, the distribution of the collagen fibers was observed after masson staining, his-tochemistry was done to observe the expression of collagen Ⅰ; The positive area rate of the collagen fibers and the average optical rate of collagen Ⅰ were quantified. Results HE staining indicated that collagen fibers were reduced in the TGF β 3 group. Masson staining shown that the collagen fibers were distributed around the blood vessel, in the portal area and disse space. Compared to the model group (13.2%±2.2%) and negative control group (12.3%±1.5%), the collagen fibers in liver tissues of TGF β3 group (7.7% ± 1.5%) were significantly decreased (q = 9.456, P < 0.01; q = 8.217, P < 0.01). Histochemistry indicated that the collagen fibers of liver tissues of TGF 15 3 group (0.185±0.033) were significantly higher than those in the model group (0.252±0.042) and the negative control group (0.230±0.029), (q = 6.228, P < 0.01; q = 4.346, P < 0.01). Conclusion TGF β 3 alleviates the damage to hepatic cell and the level offibrosis in CCI4 treated rats and inhibits the expression of collagen Ⅰ.     

国产小型模拟硅凝胶乳房假体所致组织学反应的实验研究

将国产小型模拟硅凝胶乳房假体、硅胶膜和硅凝胶分别置入大白鼠体内，经一段时间后取出，通过光镜和电镜检查其周围包膜的组织成分和结构特点。结果显示包膜由存在炎性细胞浸润的纤维组织构成，具有收缩特性。假体周围包膜是由硅胶膜、外渗的硅凝胶颗粒和假体的机械作用共同刺激所致。假体肌下置入包膜挛缩较轻，是肌肉对包膜的持续压力与包膜挛缩相对抗之故。     

云南白药与利多卡因凝胶治疗急性肛裂52例

急性肛裂是由于肛管撕裂引起，其起病急、进展快，是肛肠外科临床治疗难题。本人近几年用云南白药与利多卡因凝胶治疗急性肛裂，收到良好疗效，现报告如下。     

皮肤肿瘤

瘢痕疙瘩家系永生淋巴细胞株的建立及其染色体分析；雷公藤多甙片对皮肤瘢痕成纤维细胞生长及胶原合成影响的研究；曲尼司特胶囊治疗瘢痕疙瘩、增生性瘢痕疗效观察；瘢痕疙瘩一家系谱；棘层松解角化不良性表皮痣并发色素性毛表皮痣；