比特力联合甘利欣治疗慢性荨麻疹30例观察

我们于2004年8月-2005年10月应用盐酸西替利嗪（比特力：成都恒瑞制药有限公司）联合甘草酸二铵（甘利欣：连云港正大天晴制药有限公司）治疗慢性荨麻疹，并与单用比特力治疗进行比较，现报道如下。     

COPD患者联合使用支气管扩张药沙美特罗和噻托溴铵的疗效评估[英]／Baloira VA …//Arch Bronconeumol．

慢性阻塞性肺疾病（COPD）影响了9％的成人，预计到2020年将成为西方国家的第三大死亡原因。治疗的首要原则是缓解症状和减少加重人数。支气管扩张约噻托溴铵为一种长效抗胆碱能药物，最近已成为治疗COPD的一线药物。目前还没有联用两种长效支气管扩张药的研究，本试验旨在确定联用沙美特罗和噻托溴铵是否比单独应用能较好地改善COPD患者的肺功能。     

还原型谷胱甘肽联合甘草酸二铵对腹部开放伤后海水浸泡犬肝功能损伤的治疗作用

Objective To investigate effect of reduced glutathione and diammonium glycyrrhizinate on the treatment of hepatic damage in experimental dogs following open abdominal injuries coupled with seawater immersion. Methods Twenty-four dogs with open abdominal injuries were randomly divided into 3 groups: the control group (given with simple observation after 1.5 h seawater immersion); the routine treatment group (given routine care and fluid transfusion after 1.5 h seawater immersion) ; the hepatic treatment group (given routine are, fluid transfusion and hepatic treatment as well, after 1.5 h seawater immersion). Each group consisted of 8 dogs. Blood samples were taken at different time points to measure total bilirubin (TB), alanine aminotransferase (ALT), aspartate aminotransferase (AST), lactate dehydrogenase (LDH), prothromin time (PT), endotoxin, tumor necrosis factor-α(TNF-α), interleukin-6 (IL-6), and pathological examination was also made at the same time. Results For the control group, contents of TB, ALT, AST and LDH increased significantly and survival time was less than 24 hours. Contents of TB, ALT, AST and LDH of the routine treatment group also increased significantly, but survival time of all the experimental animals was mere than 24 hours. Reduced glutathione and diammonium glycyrrhizinate could reduce the extent of lesion quite significantly 12～24 hours following open abdominal injuries. Conclusions Reduced glutathione and diammonium glycyrrhizinate seemed to have good effects on the treatment and prevention against hepatic damage induced by trauma coupled with seawater immersion. It could be used as a primary means for the treatment of such kind of hepatic damage.     

爱全乐雾化液雾化吸入治疗分泌性中耳炎的临床疗效观察

分泌性中耳炎（secretory otitis media，SOM）是以中耳积液（包括浆液、黏液或浆黏液）及听力下降为主要特征的中耳炎性疾病。我科自2001年1月～2005年10月采用吸入用异丙托溴铵溶液（爱全乐）雾化吸入法辅助治疗分泌性中耳炎，取得较好的疗效，现报告如下。     

溴隐亭治疗垂体催乳素瘤及其机制的研究

近20年来，垂体瘤的药物治疗已有巨大进展。然后去认为药物治疗为铺助方法，但临床研究表明，对于某些肿瘤如垂体催乳素瘤（PRL腺瘤），药物治疗已成为主要的治疗方法。本研究从2002年1月至2005年12月应用溴隐亭治疗PRL腺瘤，观察其疗效并探讨其作用机制。     

普鲁本辛治疗氯氮平所致流涎副反应100例

精神病人服用氯氮平后会产生不同程度的流涎副反应,单用普鲁本辛治疗最终治愈率为100%,且无副作用。小剂量普鲁本辛可作为治疗氯氮平所致流涎症状的常规手段。     

流产后子宫内异症和溢乳症能再怀孕吗

我因感冒流产，后又发现子宫内膜异位症，做了双侧卵巢囊肿剥离术，随之而来的右侧乳房又有乳汁分泌，服用溴隐亭，收效不大，甚为烦恼。请问像我这种情况，能否治愈?有无再怀孕希望?     

新型纳米根管充填材料对成骨细胞生长的影响

通过体外培养的成骨细胞,采用二甲基噻唑二苯基四唑溴盐比色法和流式细胞术对新型纳米根管充填材料(nHA-PA66)作用下的成骨细胞生长情况的变化进行研究,评价其对成骨细胞生长的影响。以该材料的细胞培养基浸提液作用于实验组细胞,对照组采用培养基本身。实验组和对照组成骨细胞的生长情况和细胞周期无显著性差异,表明该新型纳米材料对成骨细胞的生长和细胞周期无不良影响。提示新型纳米根管充填材料的成骨细胞相容性较好,具有用作根充材料的基础。     

S38-62脂肪胺的氮杂MichaeI反应Varala R等[Synlett,2006．（10）：1549]

脂肪胺和α，β-不饱和羰基化合物的水溶液，以3mol％硝酸铈铵为催化剂，室温搅拌制得相应的B．氨基羰基化合物。环状仲胺5～30min即可完成；芳香胺不反应。20例收率55％～99％。