Neoomphaloplasty: An Old and New Technique

The authors review several proposed approaches to neoomphaloplasty, with emphasis on the use of three flaps anchored to the fascia, allowing the exposed central area to heal unaided. The procedure is straightforward and can be performed singly or during abdominoplasty. Results are both cosmetic and natural-looking.     

新生儿脐部目标性监测分析

目的研究新生儿脐部细菌定植及感染的危险因素。方法采用目标性监测方法 ,研究新生儿脐部细菌定植及感染情况,并对14项相关危险因素进行单因素和多因素非条件Logistic回归分析。结果 346例新生儿脐部有细菌定植327例,定植率为94.51%,脐部感染39例,感染率11.27%,主要为大肠埃希菌、金黄色葡萄球菌、其他肠道杆菌及耐药菌等,脐带结扎位置、脐带残端长度、脐带直径、脐带贴污染脐部是脐部感染的独立危险因素。结论新生儿脐部易发生细菌定植与感染,控制其危险因素,可预防感染的发生。     

Modified Mini-Abdominoplasty: Navel Transposition and Horizontal Residual Scar

The classic mini-abdominoplasty is a surgery generally indicated for cases in which cutaneous laxity of the abdomen's inferior region is associated with adiposity. However, in some cases, the characteristics of the abdomen are such that resort to a traditional mini-abdominoplasty would involve an unsatisfactory final result due to the unavoidable caudalization of the navel. In answer to this problem, Pontes developed the type 4 modified mini-abdominoplasty. This procedure adds to the classic technique a complete resection of the navel and its transposition so that it leaves a residual vertical scar. With our version of the technique, the scar is more aesthetic in shape and appearance, horizontal, and parallel to the suprapubic scar.     

三香散外敷脐部配合改良式肛管排气治疗腹胀30例

临床上引起腹胀的原因很多,常见于消化系统功能障碍,轻者表现为食欲下降,睡眠紊乱,严重的可引起烦躁不安、呼吸困难、呻吟不止,甚至发生腹腔间室综合症,影响呼吸循环功能.临床上常单用三香散外敷脐部或常规的肛管排气,效果并不明显.我科自2008年～2009年对腹胀病人采用了三香散外敷脐部加一次性肛管外接一次性负压引流器进行肛管排气,取得了满意的效果,现报告如下.     

彩色多普勒血流图监测胎儿脐动脉血流频谱临床价值

目的：探讨彩色多普勒监测胎儿脐动脉血流动力学的临床价值。方法：应用彩色多普勒血流显像技术，对５２例不同孕周的胎儿进行血流动力学检测。结果：发现正常妊娠时胎儿脐动脉的搏动指数、阻力指数、收缩期最高峰值血流速度／舒张末期最低血流速度比值随孕龄的增加而下降；胎儿宫内发育迟缓时，孕２２周即出现搏动指数、阻力指数、收缩期最高峰值血流速度／舒张末期最低血流速度比值异常，与正常组相比均有显著或极显著性差异。结论：彩色多普勒血流显像技术检测脐动脉血流是观察胎儿血循环的敏感指标，是目前最可靠的监测方法     

Current Research on Reducing Pre‐ and Post‐harvest Aflatoxin Contamination of U.S. Almond,Pistachio, and Walnut

Aflatoxins are considered to be potent carcinogens and teratogens to humans and farm animals. A variety of species of the fungal genus Aspergillus (mainly A. flavus and A. parasiticus) synthesize aflatoxins. Spores of these fungi are common in air and soil of agricultural areas of temperate and tropical environments. Because aflatoxigenic fungi are ubiquitous and opportunistic, aflatoxin contamination has become a food safety concern. The chief U.S. crops affected by the threat of contamination with aflatoxin include corn, peanuts, cottonseed, and certain tree nuts. Additionally, aflatoxin contamination has also become an international trade issue. Major trading partners of U.S. agricultural products have set total aflatoxin action threshold levels at four ng/g (ppb). This action level is far below the 20 ppb level recommended by the U.S. Food and Drug administration for domestic foods. Almonds, pistachios and walnuts are one of the major food commodities affected by food safety and trade issues associated with aflatoxin contamination. Commercial domestic production of these tree nuts in the U.S. is entirely in California. Moreover, 50 to 75% of domestically produced tree nuts are exported, chiefly to countries of the European Union (EU), which adhere to the four ppb action threshold level. Scientists at the USDA's Western Regional Research Center and the University of California, Davis' Department of Pomology and Kearney Agricultural Center have developed products and methods to reduce aflatoxin contamination of tree nuts. Control of insect pests in tree nut orchards is a major strategy to curtail aflatoxin contamination. Insect feeding damage can lead to fungal infection and concomitant aflatoxin contamination. This is especially the case with navel orangeworm on pistachio and almond. A new and potent lure has been developed to control codling moth, a major insect pest of walnuts whose feeding damage potentially leads to fungal infection. Through breeding and genetic engineering, new varieties of almonds and walnuts have been developed which are resistant to insect attack. New orchard management strategies have been prescribed to reduce reservoirs of A. flavus in tree nut orchards. A number of saprophytic yeasts, natural to tree nut orchards, have been discovered which show promise as biological control agents of A. flavus, in vitro, and are awaiting field testing. New and improved risk assessment models have been developed for sampling and measuring aflatoxin contamination through the processing stream and in bulk shipping lots of tree nuts. An automated sorter that detects and removes aflatoxin contaminated nuts from a processing stream in real time was developed. It was also concluded that methods currently used for hand‐cracking of closed shell pistachios result in a higher risk of aflatoxin contamination. Perhaps the foremost breakthrough to date, however, is that constituents of walnut seed coat, especially from the cultivar ‘Tulare’, are potent inhibitors of aflatoxin biosynthesis, capable of rendering aflatoxigenic A. flavus virtually atoxigenic.     

Identification and characterization of murine adipose tissue-derived somatic stem cells of Shenque (CV8) acupoint

Background:Shenque (CV8) acupoint is located on the navel and has been therapeutically used for more than 2000 years in Traditional Chinese Medicine (TCM). However, clinical research on the underlying therapeutic molecular mechanisms of the CV8 acupoint lags far behind. This study aimed to study the mechanisms of umbilical acupoint therapy by using stem cells.Methods:The morphological characteristics of CV8 acupoint were detected under a stereomicroscope using hematoxylin and eosin (H&E) staining. Oil Red, Masson, and immunohistochemical staining on multi-layered slices were used to identify the type of cells at the CV8 acupoint. Cell proliferation was measured by a cell counting kit-8 (CCK-8) method. Flow cytometry and immunohistochemistry were used for cell identification. Induced differentiation was used to compare the differentiation of cells derived from CV8 acupoint and non-acupoint somatic stem cells into other cell types, such as osteogenic, adipogenic, and neural stem cell-like cells.Results:Morphological observations showed that adipose tissues at the linea alba of the CV8 acupoint in mice had a mass-like distribution. Immunohistochemical staining confirmed the distribution of stem cell antigen-1 (Sca-1) positive cells in the multi-layered slices of CV8 acupoint tissues. Cells isolated from adipose tissues at the CV8 acupoint exhibited high expression of Sca-1 and CD44 and low expression of CD31 and CD34, and these cells possessed osteogenic, adipogenic, and neurogenic stem cell-like cell differentiation ability. The cell proliferation (day 4: 0.5138 ± 0.0111 vs. 0.4107 ± 0.0180, t = 8.447, P = 0.0011; day 5: 0.6890 ± 0.0070 vs. 0.5520 ± 0.0118, t = 17.310, P < 0.0001; day 6: 0.7320 ± 0.0090 vs. 0.6157 ± 0.0123, t = 13.190, P = 0.0002; and day 7: 0.7550 ± 0.0050 vs. 0.6313 ± 0.0051, t = 42.560, P < 0.0001), adipogenic ([9.224 ± 0.345]% vs. [3.933 ± 1.800]%, t = 5.000, P = 0.0075), and neurogenic stem cell-like cell differentiation (diameter < 50 μm: 7.2000 ± 1.3040 vs. 2.6000 ± 0.5477, t = 7.273, P < 0.0001; diameter 50–100 μm: 2.6000 ± 0.5477 vs. 1.0000 ± 0.7071, t = 4.000, P = 0.0039; and diameter >100 μm: 2.6000 ± 0.5477 vs. 0.8000 ± 0.8367, t = 4.025, P = 0.0038) were significantly enhanced in somatic stem cells derived from the CV8 acupoint compared to somatic stem cells from the groin non-acupoint. However, cells possessed significantly weaker osteogenicity ([2.697 ± 0.627]% vs. [7.254 ± 0.958]%, t = 6.893, P = 0.0023) in the CV8 acupoint group.Conclusions:Our study showed that CV8 acupoint was rich with adipose tissues that contained abundant somatic stem cells. The biological examination of somatic stem cells derived from the CV8 acupoint provided novel insights for future research on the mechanisms of umbilical therapy.     

中药脐疗治疗功能性便秘80例临床观察

目的:观察中药脐疗治疗功能性便秘的疗效。方法:80例功能性便秘患者随机分组,分别运用中药脐疗和麻仁软胶囊治疗。并采用肉眼、粪检观察大便次数、质地,并同时观察患者腹部胀满等临床表现。结果:中药脐疗组治疗总有效率92.5%,对照组为67.5%,两组比较差异有统计学意义(P<0.05)。结论:中药脐疗治疗功能性便秘的疗效优于对照组,且简便易行。     

输注脐血对恶性肿瘤患者外周血象及免疫功能的影响检测

目的 观察输注脐血对恶性肿瘤化疗患者外周血象及免疫功能的影响.方法 将研究对象150例,按住院治疗的先后顺序随机分为观察组和对照组各75例.观察组在采用化疗的基础上给予新鲜脐血输注,而对照组则只采用化疗,观察两组外周血象及免疫功能各项指标的变化.结果 观察组输注脐血后外周血象白细胞和血小板水平明显提高,两组差异有统计学意义(P<0.01).免疫功能各项指标CD+3、CD+4、CD+8和NK细胞活性明显提高,两组差异有统计学意义(P<0.05).结论 恶性肿瘤患者在化疗的同时辅助输入脐血,可提高外周血象白细胞和血小板水平,提高患者免疫功能.     

益肾活血法配合敷脐治疗前列腺增生症

目的:观察内服益肾活血中药配合敷脐疗法在治疗前列腺增生中的作用。方法:自2011年11月~2013年5月,对诊断明确,资料完整,观察系统的68例病例治疗结果进行分析。结果:益肾活血法配合敷脐疗法治疗前列腺增生疗效显著,简便易行,患者易于接受。