全文获取类型
收费全文 | 11474篇 |
免费 | 1187篇 |
国内免费 | 241篇 |
专业分类
耳鼻咽喉 | 231篇 |
儿科学 | 255篇 |
妇产科学 | 199篇 |
基础医学 | 2122篇 |
口腔科学 | 127篇 |
临床医学 | 1608篇 |
内科学 | 1399篇 |
皮肤病学 | 60篇 |
神经病学 | 283篇 |
特种医学 | 429篇 |
外国民族医学 | 4篇 |
外科学 | 1505篇 |
综合类 | 1544篇 |
预防医学 | 498篇 |
眼科学 | 139篇 |
药学 | 505篇 |
3篇 | |
中国医学 | 1002篇 |
肿瘤学 | 989篇 |
出版年
2024年 | 38篇 |
2023年 | 170篇 |
2022年 | 381篇 |
2021年 | 514篇 |
2020年 | 528篇 |
2019年 | 453篇 |
2018年 | 405篇 |
2017年 | 423篇 |
2016年 | 483篇 |
2015年 | 454篇 |
2014年 | 876篇 |
2013年 | 772篇 |
2012年 | 739篇 |
2011年 | 733篇 |
2010年 | 625篇 |
2009年 | 573篇 |
2008年 | 515篇 |
2007年 | 506篇 |
2006年 | 424篇 |
2005年 | 381篇 |
2004年 | 352篇 |
2003年 | 307篇 |
2002年 | 295篇 |
2001年 | 235篇 |
2000年 | 136篇 |
1999年 | 152篇 |
1998年 | 191篇 |
1997年 | 169篇 |
1996年 | 144篇 |
1995年 | 121篇 |
1994年 | 96篇 |
1993年 | 93篇 |
1992年 | 71篇 |
1991年 | 75篇 |
1990年 | 57篇 |
1989年 | 64篇 |
1988年 | 57篇 |
1987年 | 46篇 |
1986年 | 57篇 |
1985年 | 41篇 |
1984年 | 30篇 |
1983年 | 22篇 |
1982年 | 12篇 |
1981年 | 24篇 |
1980年 | 13篇 |
1979年 | 10篇 |
1978年 | 14篇 |
1977年 | 5篇 |
1976年 | 6篇 |
1973年 | 6篇 |
排序方式: 共有10000条查询结果,搜索用时 0 毫秒
1.
2.
《Journal of vascular and interventional radiology : JVIR》2021,32(10):1449-1456
PurposeTo investigate the safety and efficacy of thyroid artery embolization (TAE) in the treatment of nodular goiter (NG).MethodsDuring a 5.5-year period, 56 consecutive patients with a NG underwent TAE. In Group A, there were 20 patients with a solitary/dominant 5–11-cm nodule, and in Group B, there were 36 patients with numerous nodules. Of the 56 patients, 47 (84%) had a retrosternal goiter and 25 had hyperthyroidism. In all patients, clinical and radiological evaluations were made at baseline and 6 months after TAE, and these parameters were statistically compared.ResultsIn 56 patients, 145 of the 146 thyroid arteries were successfully embolized. The 30-day mortality rate was 1.8%. Minor and major complications occurred in 25 and 2 patients, respectively. Six months after the TAE, the mean nodule volume was reduced from 80.2 mL to 25.0 mL, the mean thyroid volume was reduced from 147.0 mL to 62.6 mL, and the mean intrathoracic extension was reduced from 31.7 mm to 15.9 mm (P < .001). Of the 22 patients with non–Graves hyperthyroidism, 19 (86%) became euthyroid. The mean thyroid-related patient-reported outcome scores improved from 155.4 to 70.4 (P < .001). Of the 51 patients, 50 (98%) declared that they would recommend TAE to other patients with NG.ConclusionsTAE is safe and effective for the treatment of NG, with a significant volume reduction of the nodule(s) and thyroid gland. 相似文献
3.
4.
5.
María del Carmen Azorín Samper Marta Hernandorena Gonzlez Alberto Ibez Arias Sandra Díaz Sierra Marta Bertolo Domínguez Flix Checa Ayet 《The breast journal》2020,26(2):252-254
Breast pseudoaneurysms after a core needle biopsy are a rare complication with a low incidence. However, it is important to be aware of the possibility of complications that require treatment. 相似文献
6.
Can EGFR mutation status be reliably determined in pre‐operative needle biopsies from adenocarcinomas of the lung?
下载免费PDF全文
![点击此处可从《APMIS : acta pathologica, microbiologica, et immunologica Scandinavica》网站下载免费的PDF全文](/ch/ext_images/free.gif)
Kim Hein Lindahl Flemming Brandt Sørensen Søren Peter Jonstrup Karen Ege Olsen Siegfried Loeschke 《APMIS : acta pathologica, microbiologica, et immunologica Scandinavica》2015,123(4):289-297
The identification of EGFR mutations in non‐small‐cell lung cancer is important for selecting patients, who may benefit from treatment with EGFR tyrosine kinase inhibitors. The analysis is usually performed on cytological aspirates and/or histological needle biopsies, representing a small fraction of the tumour volume. The aim of the present investigation was to evaluate the diagnostic performance of this molecular test. We retrospectively included 201 patients with primary adenocarcinoma of the lung. EGFR mutation status (exon 19 deletions and exon 21 L858R point mutation) was evaluated on both pre‐operative biopsies (131 histological and 70 cytological) and on the surgical specimens, using PCR. Samples with low tumour cell fraction were assigned to laser micro‐dissection (LMD). We found nine (4.5%) patients with EGFR mutation in the lung tumour resections, but failed to identify mutation in one of the corresponding pre‐operative, cytological specimens. Several (18.4%) analyses of the pre‐operative biopsies were inconclusive, especially in case of biopsies undergoing LMD and regarding exon 21 analysis. Discrepancy of mutation status in one patient may reflect intra‐tumoural heterogeneity or technical issues. Moreover, several inconclusive results in the diagnostic biopsies reveal that attention must be paid on the suitability of pre‐operative biopsies for EGFR mutation analysis. 相似文献
7.
8.
9.
Michael A. Gibney David Fitz-Patrick David C. Klonoff Shahista Whooley Betty Lu Wen Yue 《Current medical research and opinion》2020,36(10):1591-1600
Abstract