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71.
真皮下血管网岛状皮瓣抗菌力的实验研究 总被引:2,自引:0,他引:2
为研究真皮下血管网薄皮瓣用于感染创面的可行性,在家猪臀部两侧分别形成以旋髂深血管主干分支为蒂的传统岛状皮瓣和远侧50%修薄的真皮下血管网岛状皮瓣。用细菌计数、吖啶橙荧光染色测定白细胞吞噬指数和白细胞内杀菌率,应用激光多普勒、墨汁灌注、透明标本等方法,对两种皮瓣的抗菌力作自身对照研究。结果表明,真皮下血管网岛状皮瓣的抗菌力明显降低,可能与皮瓣修薄后血供减少,白细胞功能相应降低有关。 相似文献
72.
地塞米松在大鼠缺血随意皮瓣中的作用 总被引:2,自引:0,他引:2
目的:研究局部使用地塞米松对大鼠缺血随意皮瓣的作用。方法:建立大鼠背部缺血随意皮瓣的动物模型,随机分为2组,实验组术后皮瓣下一次给予地塞米松5mg(用生理盐水稀释至3ml),对照组术后皮瓣下一次给予0.9%生理盐水3ml。均于术后7d取材,测定皮瓣坏死率和组织中丙二醛含量,观察大体及病理切片。结果:实验组皮瓣坏死率和丙二醛含量较对照组显著降低(P<0.01)。光镜下,实验组的炎性反应较对照组明显减轻。结论:地塞米松能提高缺血随意皮瓣的成活率,大剂量一次性给药的方法是可行的。 相似文献
73.
A binocular machine vision system for three-dimensional surface measurement of small objects 总被引:1,自引:0,他引:1
Rendering three-dimensional information of a scene from optical measurements is very important for a wide variety of applications. However, computer vision advancements have not yet achieved the accurate three-dimensional reconstruction of objects smaller than 1 cm diameter. This paper describes the development of a novel volumetric method for small objects, using a binocular machine vision system. The achieved precision is high, providing a standard deviation of 0.04 mm. The robustness, of the system, issues from the lab prototype imaging system with the crucial z-axis movement without the need of further calibration and the fully automated volumetric algorithms. 相似文献
74.
100例2型糖尿病患者交感神经皮肤反应研究 总被引:1,自引:0,他引:1
目的探讨交感神经皮肤反应(SSR)检测在评价2型糖尿病(T2DM)自主神经损害中的价值.方法对100例T2DM患者进行SSR检测,30例健康志愿者作为对照.结果2组SSR的起始潜伏期、N波潜伏期、波幅、面积比较差异有显著性意义(P<0.05),P波潜伏期差异无显著性意义(P>0.05).T2DM组72例(72%)患者至少有一肢SSR异常.血糖控制满意组和血糖控制不良组比较,起始和N波潜伏期差异有统计学意义(P<0.05),波幅和面积无显著性意义(P>0.05).T2DM组病程<5年与病程≥5年比较,潜伏期、波幅、面积差异均无统计学意义(P>0.05).结论SSR可作为评价T2DM自主神经损害的客观电生理指标;T2DM患者SSR与血糖控制水平相关,与病程无关. 相似文献
75.
Do ethnicity and gender have an impact on pain thresholds in minor dermatologic procedures? 总被引:3,自引:0,他引:3
Gil Yosipovitch Gregory Meredith Yiong Huak Chan Chee Leok Goh 《Skin research and technology》2004,10(1):38-42
Background and Objectives: The perception of pain is a personal experience influenced by many factors, including genetic, ethnic and cultural issues. Understanding these perceptions is especially important in dermatologic patients undergoing minor surgical operations and who often differ in their pain response to surgical treatments. Little is known about how these differences affect the perception of experimental pain. The purpose of this study was to determine experimental pain perception differences in three distinct East Asian ethnic populations.
Methods: Pain thresholds were examined with a psychophysical computerized quantitative thermal sensory testing device (TSA 2001) in healthy volunteers recruited from three different Asian ethnic groups. Using the methods of limits, experimental pain perception threshold was measured on the forehead and volar aspect of the forearm in 49 healthy subjects. The measurements were then repeated after skin barrier perturbation with adhesive tape stripping of the stratum corneum. All three ethnic groups were analyzed separately with respect to age, gender educational level and skin type.
Results: A total of 20 Chinese, 14 Malay and 15 Indian subjects completed the study. Thermal pain thresholds were similar in all three ethnic groups before and after tape strippings. No significant differences were noted between genders.
Conclusions: Using quantitative sensory thermal testing, we demonstrated that no significant differences in pain occur between different races and genders. 相似文献
Methods: Pain thresholds were examined with a psychophysical computerized quantitative thermal sensory testing device (TSA 2001) in healthy volunteers recruited from three different Asian ethnic groups. Using the methods of limits, experimental pain perception threshold was measured on the forehead and volar aspect of the forearm in 49 healthy subjects. The measurements were then repeated after skin barrier perturbation with adhesive tape stripping of the stratum corneum. All three ethnic groups were analyzed separately with respect to age, gender educational level and skin type.
Results: A total of 20 Chinese, 14 Malay and 15 Indian subjects completed the study. Thermal pain thresholds were similar in all three ethnic groups before and after tape strippings. No significant differences were noted between genders.
Conclusions: Using quantitative sensory thermal testing, we demonstrated that no significant differences in pain occur between different races and genders. 相似文献
76.
Differential Stripping: Determination of the Amount of Topically Applied Substances Penetrated into the Hair Follicles 下载免费PDF全文
Alexa Teichmann Ute Jacobi Michael Ossadnik† Heike Richter Stefan Koch† Wolfram Sterry Jürgen Lademann 《Journal of general internal medicine》2005,20(5):264-269
The determination of penetration pathways of topically applied substances into the skin is the subject of several investigations. Recently, follicular penetration has become a major focus of interest. To date, a direct, non-invasive quantification of the amount of topically applied substance penetrated into the follicles had not been possible. The development of such a method was the aim of this study. Therefore, the advantages of both stripping techniques, tape stripping and cyanoacrylate skin surface biopsy, were combined and evaluated. Tape stripping was used to remove the part of the stratum corneum that contained the topically applied dye. Subsequently, the follicular contents were ripped off by cyanoacrylate skin surface biopsy. The combined method termed "differential stripping" was evaluated in vitro and in vivo , and the amount of topically applied fluorescent dye penetrated into the hair follicles was quantified after different penetration times. After 30 min, 5% of the recovered concentration of sodium fluorescein was found in the follicular infundibula, where it was still detectable after 48 h. Altogether, the results of this investigation revealed that differential stripping is a new method that can be used to study the penetration of topically applied substances into the follicular infundibula non-invasively and selectively. 相似文献
77.
78.
[目的] 探讨皮(肌)瓣治疗骨坏死的可行性。[方法]应用新西兰大白兔48只,随机分为对照组、实验组。按实验方法将胫骨制成骨坏死模型。对照组用游离皮片覆盖坏死骨;实验组用腓肠肌皮瓣覆盖坏死骨。术后2、4、8、12周行ECT、X线片、骨钙素(BGT)、组织切片检查。临床应用436例。[结果]ECT显示实验组动脉相放射摄入值及延迟相放射摄入值明显高于对照组(P〈0.02);血清BGP水平实验组各时段均比对照组高(P〈0.001);组织学检查4周实验组髓腔中可见增生的血管,大量骨细胞;X线片12周实验组的胫前皮质骨接近正常骨,而对照组皮质骨仍为坏死、骨质硬化。临床应用小腿外观好,足部肿胀消退,创面感染治愈,坏死骨成活,骨髓腔再通。[结论]用血运丰富的皮(肌)瓣覆盖坏死胫骨段后,血运改善,坏死骨可以成活。 相似文献
79.
目的 探讨手术治疗头面部不同类型毛细血管畸形的适应证,手术方法及疗效.方法 对适合手术的23例头面颈部患者,根据病灶的面积和手术前的条件分别采用了植皮,扩张器局部皮瓣转移修复和游离皮瓣修复等方法,并进行术后评价和随访.结果 除一例特别原因造成皮片下积血,皮片部分成活不良二期再植,一例同位素治疗后扩张器病例远端发生血运障碍后改植皮以外,其余皮片,皮瓣均成活良好,但随访皮片有较明显的色差,而皮瓣色泽,质地良好.结论 皮瓣修复效果较好,其中扩张的局部皮瓣转移修复效果最佳.游离皮瓣较适合有皮下组织萎缩的大面积的病例,而其他大面积病灶可采用分期分区植皮. 相似文献
80.