青藤碱对切口痛模型大鼠的镇痛效应及其中枢神经系统中P物质含量的影响

目的观察青藤碱对切口痛模型大鼠疼痛敏感行为及其脑脊液、脊髓中P物质含量的影响。方法 SD大鼠30只,随机分为模型组（Model）、氯诺昔康组（Lornoxicam,8mg·Kg-1）、青藤碱高剂量组（Sin-H,20mg·Kg-1）和青藤碱低剂量组（Sin-L,10mg·Kg-1）。采用机械痛敏和热痛敏测试,评价大鼠的疼痛行为。放免法检测大鼠脑脊液及脊髓L6-L8中P物质含量。结果切口痛模型大鼠的机械撤足阈值、热刺激痛感缩足时间明显改变。青藤碱高、低剂量和阳性药投与后均显示了明显的镇痛效果,其中青藤碱高剂量组镇痛效应指标优于阳性对照药氯诺昔康;给药各组大鼠脑脊液、脊髓中的P物质含量与模型组相比都下降显著,差异有统计学意义（P〈0.05）,而以青藤碱高剂量组的脑脊液P物质浓度抑制最为明显。结论青藤碱能够减轻切口痛模型大鼠疼痛敏感行为,减少P物质在中枢神经系统的释放,后者可能是青藤碱产生镇痛作用的重要机制之一。     

固定矫治器与隐形矫治器对正畸治疗疼痛影响差异的Meta分析

目的    比较在正畸治疗过程中固定矫治器与隐形矫治器对患者疼痛影响的差异。方法    计算机检索Cochrane Library、PubMed、中国知网等数据库,查找使用固定矫治器与隐形矫治器进行正畸治疗的相关文章。通过Meta分析比较在正畸治疗过程中两种矫治器对患者疼痛影响的差异。结果    共纳入11篇相关文献,其中7篇为随机对照试验（RCT）研究,4篇为对照临床试验（CCT）研究。共计患者683例,其中使用隐形矫治器（研究组）患者348例,使用固定矫治器（对照组）患者335例。Meta分析结果显示,矫治器佩戴后1、3、5、7 d,研究组患者的疼痛程度均小于对照组,差异有统计学意义（均P < 0.05）。结论    矫治器初戴1周内,隐形矫治器对患者产生的疼痛程度小于固定矫治器。临床上应用隐形矫治器可能会提高患者依从性与配合度。     

A comparison between flexible electrogoniometers,inclinometers and three-dimensional video analysis system for recording neck movement

This study compared neck range of movement recording using three different methods goniometers (EGM), inclinometers (INC) and a three-dimensional video analysis system (IMG) in simultaneous and synchronized data collection. Twelve females performed neck flexion-extension, lateral flexion, rotation and circumduction. The differences between EGM, INC, and IMG were calculated sample by sample. For flexion-extension movement, IMG underestimated the amplitude by 13%; moreover, EGM showed a crosstalk of about 20% for lateral flexion and rotation axes. In lateral flexion movement, all systems showed similar amplitude and the inter-system differences were moderate (4–7%). For rotation movement, EGM showed a high crosstalk (13%) for flexion-extension axis. During the circumduction movement, IMG underestimated the amplitude of flexion-extension movements by about 11%, and the inter-system differences were high (about 17%) except for INC–IMG regarding lateral flexion (7%) and EGM–INC regarding flexion-extension (10%). For application in workplace, INC presents good results compared to IMG and EGM though INC cannot record rotation. EGM should be improved in order to reduce its crosstalk errors and allow recording of the full neck range of movement. Due to non-optimal positioning of the cameras for recording flexion–extension, IMG underestimated the amplitude of these movements.     

Temporomandibular Disorders in Burning Mouth Syndrome Patients: An Observational Study

BACKGROUND: Burning Mouth Syndrome (BMS) is a chronic disease characterized by absence of any lesions and burning of the oral mucosa associated to a sensation of dry mouth and/or taste alterations. The purpose of our study is to estimate signs and symptoms of Temporomandibular Disorders (TMD) in patients with BMS and to investigate for the existence of an association between BMS and TMD.MATERIALS AND METHODS: Forty-four BMS patients were enrolled; BMS subtype was established according to the classification of Lamey. After a gnathological evaluation, according to the protocol of the European Academy of Craniomandibular Disorders, patients were classified by RDC/TMD criteria. The data were compared and analyzed using a chi-square test to describe the existence of an association between BMS and TMD.RESULTS: 65.9% the BMS patients showed disorders classified as primary signs and symptoms of TMD according to RDC / TMD criteria, and 72.7% showed parafunctional habits. The chi-square test revealed a statistically significant association (p = 0.035) between BMS and TMD.CONCLUSION: The data suggest that there is a possible relationship not yet well understood between BMS and TMD, may be for neurophatic alterations assumed for BMS that could be also engaged in TMD pathogenesis.     

改良式艾箱灸装置在脾胃虚寒胃脘痛病人中的应用

目的:改良式艾箱灸装置在脾胃虚寒胃脘痛病人中的应用效果。方法:将2019年6月—2019年12月收治的120例脾胃虚寒胃脘痛病人随机分成观察组和对照组各60例,观察组使用改良式艾箱灸装置,对照组使用传统式艾箱灸装置,每周4次,每次40 min,4周为1个疗程,连续治疗2个疗程。记录施灸温度-时间曲线,比较两组病人临床疗效、治疗前后视觉模拟评分法(VAS)疼痛评分、止痛起效时间,评价两组病人满意度。结果:观察组病人治疗有效率、满意度高于对照组,止痛起效时间短于对照组,治疗后VAS疼痛评分低于对照组(P<0.05)。结论:脾胃虚寒胃脘痛病人使用改良式艾箱灸装置可提高临床疗效、病人满意度,缩短止痛起效时间,缓解疼痛。     

集束化护理在胫腓骨骨折早期肿胀病人中的应用

目的:探讨集束化护理在胫腓骨骨折早期肿胀病人中的应用效果。方法:选取某医院2018年1月—2020年2月收治的80例胫腓骨骨折早期肿胀病人为研究对象,采用随机数字表法将病人分为对照组及观察组,每组40例,对照组采取常规护理,观察组采取集束化护理,比较两组病人的疼痛评分情况、骨折康复情况及并发症发生情况。结果:两组护理前后疼痛评分差异有统计学意义,且观察组疼痛评分下降幅度显著高于对照组(P<0.05);观察组康复有效率为85.00%,显著高于对照组65.00%(P<0.05);观察组并发症发生率为7.50%,显著低于对照组的22.50%(P<0.05)。结论:针对胫腓骨骨折早期肿胀病人,采用集束化护理能有效改善病人疼痛,减少并发症,取得良好的康复效果。     

Screening to Detect Hip and Groin Problems in Elite Adolescent Football (Soccer) Players – Friend or Foe?

Injury prevention strategies in team settings should not overlook early detection and secondary prevention. Monitoring systems may be an effective approach to detect common and troublesome injuries, such as hip and groin pain in football (soccer) players. The purpose of this International Perspective is to share our experiences with monitoring hip and groin pain in youth academy football and discuss challenges that surfaced. We consider why players may not accurately report pain, their perceptions of groin pain, and whether all groin pain is clinically meaningful.Level of Evidence5