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61.
Stephen D. Scoggin M.D. Richard C. Frazee M.D. Samuel K. Snyder M.D. John C. Hendricks M.D. John W. Roberts M.D. Richard E. Symmonds M.D. Randall W. Smith M.D. 《Diseases of the colon and rectum》1993,36(8):747-750
The use of laparoscopic surgical techniques is now being applied to a variety of operations traditionally performed in an open fashion. Twenty patients underwent laparoscopic-guided large and small bowel surgery at our institution from March 1991 to April 1992. The indications for surgery included polyps, obstruction, bleeding, and perforation, and pathologic diagnoses included benign polyps, lipomas, inflammatory bowel disease, perforation of a jejunal diverticulum, colonic arteriovenous malformations, and adenocarcinoma. Mobilization of the colon, ligation of the mesentery, and closure of the mesenteric defect were performed using the laparoscopic equipment. One trocar site was enlarged to 3 cm to deliver the bowel through the abdominal wall. All anastomoses were hand-sewn. Postoperative hospitalization ranged from 2 to 31 days (median, five days). No mortality was noted, and morbidity was 20 percent. We conclude that laparoscopic-guided bowel surgery is technically feasible and should translate into shorter hospitalization and less patient discomfort. 相似文献
62.
Large granular lymphocytic (LGL) leukaemia and chronic natural killer cell lymphocytosis (CNKL) are chronic indolent disorders often associated with neutropenia and constitutional symptoms. Severe anaemia occurs in about 20% of patients and is currently treated with corticosteroids followed by oral cyclophosphamide in non-responders. 30% of patients fail initial measures, and salvage therapy is inadequate. We describe three transfusion-dependent patients (two with T-LGL leukaemia, one with CNKL) refractory to corticosteroids, cyclophosphamide, and in one case fludarabine. Cyclosporine A (CSA) initiation resulted in prompt transfusion-independence and was well tolerated in all patients, making it an attractive alternative therapy for this disorder. 相似文献
63.
64.
大肠癌误诊误治较为普通。从总结经验教训出发,本文对确诊前曾发生过误诊误治的536例大肠癌进行详尽的分析。本组病例536例,曾719次先后被误诊为32种疾病,其中误诊为“痔”“痢疾”“肠炎”“肠梗阻”等最为常见,误诊为其它疾病也时有发生,严重的影响其预后。在误诊原因上,除病人自误外,与医生责任心不强,询问病史不细,本行或未认真行有关检查,特别是直肠指诊检查和结肠内窥镜检查是分不开的。文章就今后如何减少误诊,提高早期诊断率,提出了5点措施,强调了直肠指诊和结肠内窥镜检查的重要价值。 相似文献
65.
Summary Obturator hernias comprise a rare group of abdominal hernias. They are often diagnosed when the small bowel has become obstructed
and the patients are operated on without the causes of the obstruction being known. Although many techniques for closure of
the defect are available, there is no agreement at the present time as to which is the procedure of choice. 相似文献
66.
A quantitative immunocytochemical study of large granular lymphocytes (LGLs) in the normal cervix and in human papillomavirus (HPV) associated disease was performed using a panel of monoclonal antibodies which included those for LGL surface markers CD56, CD16, and CD57. Only CD56-positive cells were found within the ectocervical epithelium and these cells increased in number in cervical intraepithelial neoplasia (CIN) in comparison with normal cervix. Examination of serial sections and double labelling suggests that these cells are CD3+, CD8+, CD56+, CD16+. The observed increase in number of this subset was not associated specifically with HPV infection but was related to CIN. Lymphocytes expressing all three LGL markers were found in the stroma and CD16(+)-positive cells clustered around endocervical glands with occasional cells extending into the endocervical epithelium. These results indicate that a small subset of LGLs which express T-cell markers is increased in number in CIN. Cells expressing classical NK markers are restricted to the stroma and are not found within the ectocervical epithelium. 相似文献
67.
人大肠癌细胞体外常温及温热环境中药物敏感性试验 总被引:1,自引:0,他引:1
用MTT比色法对20例大肠癌患者术后标本在常温及温热环境中进行体外药物敏感性试验,结果显示,某些药物在温热环境中,对癌细胞的杀伤作用有显著提高,此项试验为临床温热化疗法提供了理论依据。 相似文献
68.
大型医院病案信息化的管理与实践 总被引:3,自引:0,他引:3
病案作为医学临床信息的重要载体,只有将其进行海量存储、快速查阅、远程传输,使之活跃起来,才能真正地满足医疗、教学、科研和管理的需要。将传统的纸质病案进行扫描后保存为光盘,并存入光盘镜像服务器中,实现了网上实时访问、检索、查询、浏览和传输功能,并可以利用病案管理软件进行相应的统计和分析。为医疗信息资源进一步开发和利用,探索了一条大型医院病案信息化管理的有效途径。 相似文献
69.
大鼠肝小肠联合移植模型的建立 总被引:1,自引:0,他引:1
孙晓毅 《中华器官移植杂志》1997,18(4):194-195
本文报告一种封闭群大鼠进行的肝小肠联合移植模型。术中供体肝与小肠整块游离和灌注,分开切取。供肝原位、供肠异位移植于受体大鼠。主要血管用Kamada袖套法吻合,正式实验21次,3天以上存活率为43%。结果表明:减少手术时间和简化操作技术是提高成功率的关键因素和基本原则。 相似文献
70.
W. E. Whitehead G. Bassotti O. Palsson E. Taub E. C. Cook III D. A. Drossman 《Digestive and liver disease》2003,35(11):229-783
BACKGROUND AND AIMS: Functional gastrointestinal disorders are diagnosed by the presence of a characteristic set of symptoms. Aims of this study were to validate the Rome symptom criteria by factor analysis and to determine whether symptoms cluster in the same way in different cultures. METHODS: One thousand forty-one gastroenterology clinic patients in the US (response rate 53%) and 228 family members accompanying clinic patients in Italy (84%) completed a previously validated symptom questionnaire. Factor analysis identified clusters of symptoms which are highly correlated with each other, and these were compared to the Rome diagnostic criteria. RESULTS: In the US, 13 factors were identified. The irritable bowel factor was composed of three core symptoms corresponding to the Rome II classification system. Two dyspepsia factors were identified which correspond to the ulcer- and motility-like subtypes proposed in the Rome I classification system. All symptoms of constipation formed a single cluster as proposed in the Rome II classification system. Symptom clusters in the US agreed well with symptom clusters identified in Italian subjects. CONCLUSIONS: Empirically derived symptom clusters agree in most respects with the Rome II classification system and support their validity. These symptom clusters are independent of cultural differences in diet and behaviour. 相似文献