Quadruplet in vitro fertilization pregnancy complicated by fetal reduction and leiomyoma

A woman had a quadruplet IVF pregnancy with a leiomyomatous uterus. Pregnancy resulted in the birth of one baby after missed abortion of one fetus and selective reduction of two others. The woman had a left deep calf vein thrombosis in the first half of pregnancy.     

恶性肿瘤累及颈动脉的外科处理

为探讨头颈部恶性肿瘤侵犯颈动脉的外科治疗，对５例喉癌或下咽癌颈淋巴结转移累及一侧颈动脉病人，术前经ＣＴ或Ｂ超检查，３例经术前体外颈动脉压迫训练合格后手术切除受累段颈总动脉，２例系术中损伤颈总动脉后紧急切除受轻动脉。其中１例即刻行断端吻合，５例术中，术后均无明显脑缺血表现，３例术后随访２年以上健在，２例尚在随访中。     

超选择动脉栓塞治疗血管搏动性耳鸣（附2例报告）

采用数字减影血管造影技术超选择性动脉栓塞治愈２例血管搏动怀耳鸣，并就发病原因、机理、治疗措施、临床特征进行讨论。     

Glucocorticoids exacerbate insult-induced declines in metabolism in selectively vulnerable hippocampal cell fields

Glucocorticoids (GCs), the adrenal steroids released during stress, can compromise the ability of hippocampal neurons to survive necrotic neurological insults. This GC-induced endangerment has energetic facets, in that it can be attenuated with energy supplementation. In the present report, we studied the effects of GCs on the metabolic response of specific hippocampal cell fields to necrotic insults. We used silicon microphysiometry, which allows indirect measurement of metabolism in real time in tissue explants. Aglycemia caused a significant decline in metabolism in dentate gyrus explants, but not in CA1 or CA3 explants. When coupled with our prior report of cyanide disrupting metabolism only in CA1 explants, and the glutamatergic excitotoxin kainic acid disrupting metabolism only in CA3 explants, this demonstrates that microphysiometry can detect the selective regional vulnerability that characterizes the hippocampal response to these necrotic insults. We then examined the effects of GCs on the response to these insults, monitoring explants taken from rats that were adrenalectomized, intact, or treated with corticosterone (the GC of rats) that produced circulating levels equivalent to those of major stressors. Increased exposure to GCs worsened the decline in metabolism in dentate gyrus explants induced by hypoglycemia, and in CA1 explants induced by cyanide (after eliminating the effects of glial release of lactate for the support of neuronal metabolism). Thus, GCs worsen the metabolic consequences of necrotic insults in hippocampal explants.     

选择性子宫动脉栓塞治疗子宫肌瘤32例分析

目的 研究应用选择性子官动脉栓塞治疗子宫肌瘤32例临床效果。方法 32例子宫肌瘤患者均采用经皮股动脉穿刺，两侧子宫动脉插管，经导管注入PVA颗粒，阻断肌瘤血供。结果 32例栓塞成功率96.88％，随访6个月，月经量及月经周期恢复正常，贫血好转。术后3个月瘤体平均缩小40％以上；术后6个月瘤体平均缩小50％以上，其中3例完全消失；无1例出现严重并发症。结论 选择性子官动脉栓塞是子宫肌瘤安全、有效的治疗方法。     

选择性肠道去污对小儿MODS防治效果的临床观察

目的研究选择性肠道去污(SDD)对小儿MODS的防治效果。方法2004年4月~2005年6月在ICU住院的符合MODS诊断的患儿60名,随机分成常规治疗组M1组(30名),常规治疗 口服庆大治疗(SDD)M2组(30名),分析研究治疗前、后两组患儿的血清炎症介质的变化、并发症的发生率和病死率。结果M1组在ICU的平均住院时间为(14.68±4.8)d,M2组为(9.69±1.56)d,(P<0.05);M1组出现感染并发症的人数多于M2组;M2组患儿中性粒细胞计数在治疗期间下降更为明显;M1组患儿血清TNF浓度在治疗前、后没有显著变化,M2组血清TNF浓度在治疗后明显降低。结论选择性肠道去污的治疗能有效减轻并发症,缩短病程,能否降低病死率有待进一步探讨。     

Immobilization of sodium alginate sulfates on polysulfone ultrafiltration membranes for selective adsorption of low-density lipoprotein

A novel method for the immobilization of sodium alginate sulfates (SAS) on polysulfone (PSu) ultrafiltration membranes to achieve selective adsorption of low-density lipoprotein (LDL) was developed, which involved the photoinduced graft polymerization of acrylamide on the membrane and the Hofmann rearrangement reaction of grafted acrylamide followed by chemical binding of SAS with glutaraldehyde. The surface modification processes were confirmed by attenuated total reflectance Fourier transform infrared spectroscopy and X-ray photoelectron spectroscopy characterization. Zeta potential and water contact angle measurements were performed to investigate the surface charge and wettability of the membranes. An enzyme-linked immunosorbent assay was used to measure the binding of LDL on plain and modified PSu membranes. It was found that the PSu membrane immobilized with sodium alginate sulfates (PSu-SAS) greatly enhanced the selective adsorption of LDL from protein solutions and the absorbed LDL could be easily eluted with sodium chloride solution, indicating a specific and reversible binding of LDL to SAS, mainly driven by electrostatic forces. Furthermore, the PSu-SAS membrane showed good blood compatibility as examined by platelet adhesion. The results suggest that the PSu-SAS membranes are promising for application in simultaneous hemodialysis and LDL apheresis therapy.     

Happy heart,smiling eyes: A systematic review of positive mood effects on broadening of visuospatial attention

Positive mood contributes to mental and physical wellbeing. The broaden-and-build theory (Fredrickson, 2001) proposed that the beneficial effects of positive mood on life quality result from attentional broadening. In this article, we systematically review (following PRISMA guidelines; Moher et al., 2009), a host of studies investigating the nature and extent of attentional changes triggered by the experience of positive mood, with a focus on vision. While several studies reported a broadening of attention, others found that positive mood led to a more diffuse information processing style. Positive mood appears to lessen attention selectivity in a way that is context-specific and bound to limitations. We propose a new framework in which we postulate that positive mood impacts the balance between internally and externally directed attention, through modulations of cognitive control processes, instead of broadening attention per se. This novel model is able to accommodate discrepant findings, seeks to translate the phenomenon of the so-called broadening of attention with positive mood into functional terms, and provides plausible neurobiological mechanisms underlying this effect, suggesting a crucial role of the anterior and posterior cingulate cortex in this interaction.