首页 | 本学科首页   官方微博 | 高级检索  
文章检索
  按 检索   检索词:      
出版年份:   被引次数:   他引次数: 提示:输入*表示无穷大
  收费全文   6544篇
  免费   336篇
  国内免费   26篇
耳鼻咽喉   35篇
儿科学   25篇
妇产科学   22篇
基础医学   231篇
口腔科学   56篇
临床医学   647篇
内科学   332篇
皮肤病学   98篇
神经病学   121篇
特种医学   106篇
外科学   203篇
综合类   465篇
预防医学   4115篇
眼科学   11篇
药学   306篇
  1篇
中国医学   29篇
肿瘤学   103篇
  2024年   6篇
  2023年   66篇
  2022年   137篇
  2021年   181篇
  2020年   194篇
  2019年   194篇
  2018年   193篇
  2017年   143篇
  2016年   146篇
  2015年   188篇
  2014年   562篇
  2013年   600篇
  2012年   582篇
  2011年   575篇
  2010年   432篇
  2009年   397篇
  2008年   359篇
  2007年   297篇
  2006年   262篇
  2005年   177篇
  2004年   148篇
  2003年   103篇
  2002年   84篇
  2001年   74篇
  2000年   71篇
  1999年   44篇
  1998年   57篇
  1997年   42篇
  1996年   49篇
  1995年   49篇
  1994年   37篇
  1993年   40篇
  1992年   50篇
  1991年   31篇
  1990年   24篇
  1989年   33篇
  1988年   41篇
  1987年   28篇
  1986年   35篇
  1985年   29篇
  1984年   27篇
  1983年   32篇
  1982年   25篇
  1981年   12篇
  1980年   16篇
  1978年   9篇
  1977年   6篇
  1976年   6篇
  1975年   4篇
  1974年   6篇
排序方式: 共有6906条查询结果,搜索用时 15 毫秒
181.
Background and OverviewThe authors set out to identify factors associated with implementation by U.S. dentists of four practices first recommended in the Centers for Disease Control and Prevention's Guidelines for Infection Control in Dental Health-Care Settings—2003.MethodsIn 2008, the authors surveyed a stratified random sample of 6,825 U.S. dentists. The response rate was 49 percent. The authors gathered data regarding dentists' demographic and practice characteristics, attitudes toward infection control, sources of instruction regarding the guidelines and knowledge about the need to use sterile water for surgical procedures. Then they assessed the impact of those factors on the implementation of four recommendations: having an infection control coordinator, maintaining dental unit water quality, documenting percutaneous injuries and using safer medical devices, such as safer syringes and scalpels. The authors conducted bivariate analyses and proportional odds modeling.ResultsResponding dentists in 34 percent of practices had implemented none or one of the four recommendations, 40 percent had implemented two of the recommendations and 26 percent had implemented three or four of the recommendations. The likelihood of implementation was higher among dentists who acknowledged the importance of infection control, had practiced dentistry for less than 30 years, had received more continuing dental education credits in infection control, correctly identified more surgical procedures that require the use of sterile water, worked in larger practices and had at least three sources of instruction regarding the guidelines. Dentists with practices in the South Atlantic, Middle Atlantic or East South Central U.S. Census divisions were less likely to have complied.ConclusionsImplementation of the four recommendations varied among U.S. dentists. Strategies targeted at raising awareness of the importance of infection control, increasing continuing education requirements and developing multiple modes of instruction may increase implementation of current and future Centers for Disease Control and Prevention guidelines.The findings and conclusions in this report are those of the authors and do not necessarily represent the official position of the Centers for Disease Control and Prevention, Atlanta.The authors thank Jon Ruesch, who when this study was conducted was the director, Survey Center, American Dental Association, Chicago, for his effort in the collection of the data for this research project. Mr. Ruesch is now retired.  相似文献   
182.
183.
Purpose: In order to enhance the quality of the data collected in a multicentre validation study of a revised Danish version of the McGill Ingestive Skills Assessment (MISA), the authors developed a rater training programme. The purpose of the present study was to evaluate the effect of the training on scoring performance and scale-specific expertise amongst raters. Method: During 2 days of rater training, 81 occupational therapists (OTs) were qualified to observe and score dysphagic clients’ mealtime performance according to the criteria of 36 MISA-items. The training effects were evaluated pre- to post-training using percentage exact agreement (PA) of scored MISA items of a case-vignette and a Likert scale self-report of scale-specific expertise. Results: PA increased significantly from pre- to post-training (Z = ?4.404, p < 0.001), although items for which the case-vignette reflected deficient mealtime performance appeared most difficult to score. The OTs scale-specific expertise improved significantly (knowledge: Z = ?7.857, p < 0.001 and confidence: Z = ?7.838, p < 0.001). Conclusion: Rater training improved OTs scoring performance when using the Danish MISA as well as their perceived scale-specific expertise. Future rater training should emphasis the items identified as those most difficult to score. Additionally, further studies addressing different training approaches and durations are warranted.
  • Implications for Rehabilitation
  • When occupational therapists (OTs) use the McGill Ingestive Skills Assessment (MISA) they observe, interpret and record occupational performance of dysphagic clients participating in a meal. This is a highly complex task, which might introduce unwanted variability in measurement scores.

  • A 2-day rater training programme was developed and this builds on the findings of several studies. These suggest that combinations of different training methods tend to yield the most effective results.

  • Participation in the newly developed training programme on how to administer the MISA significantly reduces unwanted variability in measurement scores and improves OTs’ competency.

  • The training programme could be used in undergraduate and postgraduate dysphagia education initiatives to help OTs understanding of the content and the scoring criteria for each aspect of occupational performance during a meal, thus developing observation skills as well as recognizing and avoiding the most common errors in measurement scores.

  相似文献   
184.
185.
The utility of empirical combination antimicrobial therapy for Gram-negative bloodstream infection (BSI) remains unclear. This retrospective, quasi-experimental matched cohort study examined the impact of empirical combination therapy on mortality in patients with Gram-negative BSI. Hospitalized adults with Gram-negative BSI from 1 January 2010 to 31 December 2013 at Palmetto Health Hospitals in Columbia, SC, USA were identified. Patients receiving combination therapy or beta-lactam monotherapy were matched 1:1 based on age, sex and Bloodstream Infection Mortality Risk Score (BSIMRS). Multivariate Cox proportional hazards regression with propensity score adjustment was used to examine overall 28–day mortality and within predefined BSIMRS categories (<5 and ≥5). A total of 380 patients receiving combination therapy or monotherapy for Gram-negative BSI were included in the study. Median age was 66 years and 204 (54%) were female. Overall, 28-day mortality in patients who received combination therapy and monotherapy was 13% and 15%, respectively (P?=?0.51). After stratification by BSIMRS, mortality in both combination therapy and monotherapy groups was 1.1% in patients with BSIMRS <5 (P?=?0.98) and 27% and 32%, respectively, in patients with BSIMRS ≥5 (P?=?0.47). After adjusting for propensity to receive combination therapy, risk of mortality was not significantly different for combination therapy compared to monotherapy (hazard ratio [HR] 0.90, 95% confidence interval [CI] 0.51–1.60). This finding persisted for both subgroups of BSIMRS <5 (HR 0.96, 95% CI 0.04–24.28) and BSIMRS ≥5 (HR 0.83, 95% CI 0.46–1.48). There is no survival benefit from empirical combination therapy over monotherapy in patients with Gram-negative BSI, regardless of predicted prognosis at initial presentation.  相似文献   
186.

Background

Despite increasing concerns about the health effects of climate change, the extent to which workers are affected by hot weather is not well documented. This study aims to investigate the association between high temperatures and work-related injuries using data from a large subtropical city in China.

Methods

We used workers’ compensation claims to identify work-related injuries in Guangzhou, China during 2011–2012. To feature the heat effect, the study period was restricted to the warm seasons in Guangzhou (1 May-31 October). We conducted a time-stratified case-crossover study to examine the association between ambient outdoor temperatures, including daily maximum and minimum temperatures, and cases of work-related injury. The relationships were assessed using conditional Poisson regression models.

Results

Overall, a total of 5418 workers’ compensation claims were included over the study period. Both maximum and minimum temperatures were significantly associated with work-related injuries, but associations varied by subgroup. One?°C increase in maximum temperature was associated with a 1.4% (RR?=?1.014, 95%CIs 1.012–1.017) increase in daily injury claims. Significant associations were seen for male and middle-aged workers, workers in small and medium-sized enterprises, and those working in manufacturing sector. And 1?°C increase in minimum temperature was associated with 1.7% (RR?=?1.017, 95%CIs 1.012–1.021) increase in daily injury claims. Significant associations were observed for female and middle-aged workers, workers in large-sized enterprises, and those working in transport and construction sectors.

Conclusions

We found a higher risk of work-related injuries due to hot weather in Guangzhou, China. This study provides important epidemiological evidence for policy-makers and industry that may assist in the formulation of occupational safety and climate adaptation strategies.  相似文献   
187.
目的通过了解湖南省20年职防机构人员状况,对未来几年人力资源情况进行预测,为全省及其他地区优化职业病防治人力资源的规划,提升其服务能力提供科学依据与参考。方法在已建立的湖南省职防机构基本信息管理系统中抽取有关人员资料,对1996至2015年人员数量和构成的动态变化进行描述分析,采用灰色模型GM(1,1)进行人员情况预测。结果湖南省1996年职防机构人员为1 591人,至2015年为1 429人。20年间,人员构成从"中专与无专业学历"为主转变至以"本科及以上与专科学历"为主,以"其他专业"为主至以"公共卫生与临床医学"为中坚力量,由无职称人员占比超三分之一至仅占5%左右且高级、中级、初级职称均稳步上升的状况。预测显示,2018年和2020年职防机构高学历人员构成比将分别达41.00%和45.61%,公卫人员构成比将分别达44.15%和46.60%。结论湖南省20年职防机构人员数量变化不大,人员质量有了很大的提升,有利于职防事业的可持续发展;未来5年人员学历及专业构成将进一步得到优化。  相似文献   
188.
目的 了解某采油厂在修井作业过程产生的职业病危害状况,提出相应的职业病防控措施建议。方法 依据国家相关标准,采用职业卫生调查、职业卫生检测、综合分析等方法进行综合评价。结果 采油厂修井作业过程中存在的主要职业病危害因素包括其他粉尘、甲醛、乙醛、丁醛、苯酚、苯、甲苯、二甲苯、石棉纤维、噪声等,工作场所产生的化学毒物职业病危害因素浓度均符合国家相关职业接触限值要求,但是修井机司机接触的噪声强度超过接触限值。结论 甲醛、铅尘及噪声是油田修井作业的主要职业病危害因素,其中噪声危害程度较为严重,企业应针对性地采取革新工艺,加强个体防护等措施进行控制。  相似文献   
189.
目的 分析新疆煤中天然放射性水平和铀伴生煤矿的潜在职业照射。方法 根据近年来新疆煤中天然放射性水平调查的论文报道中的数据,分析比较新疆煤中天然放射性水平。结果 通过分析发现,新疆煤中238U活度浓度与世界、美国和俄罗斯相近,232Th活度浓度低于世界、美国和俄罗斯,238U和232Th活度浓度均低于我国平均浓度,在正常自然本底变化范围内。结论 从放射卫生学角度考虑,合理开发利用新疆的煤炭资源不会对矿工和居民的健康带来额外影响。  相似文献   
190.
目的 探讨碘-125(125I)放射性粒籽植入治疗过程中可能存在的放射性职业病危害因素及辐射水平,探讨关键控制技术。方法 以5家开展125I粒籽植入治疗项目的医疗机构为研究对象,采用放射卫生学现场调查、工作场所辐射防护水平检测、人员个人剂量监测等方法,调查粒籽植入涉源工作场所及相关人员的辐射水平;结合源项分析及放射卫生管理经验,根据危害分析与关键控制点(HACCP)的原理,探讨125I粒籽植入治疗过程的关键控制点。结果 不同涉源场所中粒籽植入源运输包装、粒籽植入治疗室和专用病房工作场所各关注点的周围剂量当量率为本底~1.80 μSv/h(病房门处),均小于2.5 μSv/h;35名放射工作人员全年个人剂量监测结果为0.20~1.80 mSv,平均为0.42 mSv。结论 不同涉源场所的辐射水平及人员的受照剂量均符合国家标准限值的要求;应根据关键控制措施,对125I放射性粒籽植入治疗过程的关键环节予以控制。  相似文献   
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号