全文获取类型
收费全文 | 54898篇 |
免费 | 4624篇 |
国内免费 | 1355篇 |
专业分类
耳鼻咽喉 | 428篇 |
儿科学 | 909篇 |
妇产科学 | 411篇 |
基础医学 | 2988篇 |
口腔科学 | 655篇 |
临床医学 | 9904篇 |
内科学 | 5610篇 |
皮肤病学 | 139篇 |
神经病学 | 7335篇 |
特种医学 | 16759篇 |
外国民族医学 | 12篇 |
外科学 | 4290篇 |
综合类 | 5736篇 |
现状与发展 | 1篇 |
一般理论 | 1篇 |
预防医学 | 908篇 |
眼科学 | 432篇 |
药学 | 1948篇 |
14篇 | |
中国医学 | 384篇 |
肿瘤学 | 2013篇 |
出版年
2024年 | 147篇 |
2023年 | 773篇 |
2022年 | 1806篇 |
2021年 | 2411篇 |
2020年 | 2216篇 |
2019年 | 1962篇 |
2018年 | 1919篇 |
2017年 | 2203篇 |
2016年 | 2346篇 |
2015年 | 2167篇 |
2014年 | 3870篇 |
2013年 | 3265篇 |
2012年 | 3222篇 |
2011年 | 3594篇 |
2010年 | 3072篇 |
2009年 | 3100篇 |
2008年 | 3052篇 |
2007年 | 2845篇 |
2006年 | 2566篇 |
2005年 | 2395篇 |
2004年 | 1887篇 |
2003年 | 1498篇 |
2002年 | 1129篇 |
2001年 | 1082篇 |
2000年 | 931篇 |
1999年 | 749篇 |
1998年 | 702篇 |
1997年 | 672篇 |
1996年 | 645篇 |
1995年 | 550篇 |
1994年 | 435篇 |
1993年 | 371篇 |
1992年 | 309篇 |
1991年 | 234篇 |
1990年 | 174篇 |
1989年 | 136篇 |
1988年 | 119篇 |
1987年 | 83篇 |
1986年 | 54篇 |
1985年 | 45篇 |
1984年 | 30篇 |
1983年 | 29篇 |
1982年 | 20篇 |
1981年 | 16篇 |
1980年 | 16篇 |
1979年 | 10篇 |
1978年 | 6篇 |
1976年 | 4篇 |
1975年 | 3篇 |
1972年 | 2篇 |
排序方式: 共有10000条查询结果,搜索用时 375 毫秒
171.
A. Boussuges P. Ambrosi M. Gainnier V. Quenee J.-M. Sainty 《Intensive care medicine》1997,23(6):702-703
We describe a case of left-sided superior vena cava. The diagnosis was suggested by chest radiograph after central venous
catheter placement. This was subsequently confirmed by magnetic resonance imaging.
Received: 4 March 1997 Accepted: 21 March 1997 相似文献
172.
J. Ravensbergen B. Hillen M. Tarnawski C. G. Caro E. M. Vriens A. C. Van Huffelen 《Neuroradiology》1996,38(1):1-5
The basilar artery is the only large artery in which two flows merge, and this is reflected in the flow downstream. We report quantitative flow — velocity measurements with a phase-based MR technique, i.e. the Fourier velocity encoding method, in the basilar artery of a volunteer. To our knowledge, this has not previously been performed successfully. A comparison is made with the results of flow velocity measurements in the basilar artery with transcranial Doppler ultrasonography; the techniques agreed very well. Although Doppler ultrasonography is still most widely used, no information on the flow rate and the flow velocity distribution in the basilar artery can be provided. MR flow measurement techniques appear promising when detailed information on the flow velocity distribution and flow rate is needed. 相似文献
174.
175.
Adolf Pfefferbaum Edith V. Sullivan Margaret J. Rosenbloom Paula K. Shear Daniel H. Mathalon Kelvin O. Lim 《Psychiatry Research: Neuroimaging》1993,50(4):257-274
This cross-sectional study used a semi-automated analysis technique to quantify regional brain cerebrospinal fluid (CSF) volumes derived from computed tomography (CT) in 84 healthy men ranging from 21 to 82 years of age and 28 patients meeting Research Diagnostic Criteria for alcohol dependence. The goals were to replicate an earlier CT study of an independent sample of alcoholic and control subjects (Pfefferbaum et al., 1988a; Zipursky et al., 1988) and to compare CT assessments of brain changes with magnetic resonance imaging (MRI) assessments made in the same alcoholic patients (Pfefferbaum et al., 1992). Regional brain changes associated with normal aging were derived by regression analysis, using CT data collected from the healthy control subjects. As in the earlier CT study and in the concurrent MRI study, ventricular and sulcal CSF volumes in alcoholic patients were greater than would be expected for their age. Furthermore, the present CT study replicated the previous CT and MRI findings of a positive relationship between age and CSF volume enlargement in alcoholic patients over and above the normal age-related increase in CSF volume, suggesting greater vulnerability of the aging brain to alcohol. Comparison of CT-and MRI-derived estimates of ventricular and cortical sulcal volume revealed high correlations (>0.80). MRI and CT produced similar absolute ventricular volumes, while MRI produced larger sulcal volume estimates than did CT. The difference in sulcal volume estimate may be due to differences between CT and MRI in slice thickness and sensitivity to partial volume effects. 相似文献
176.
A comparison between fast and conventional spin-echo in the detection of multiple sclerosis lesions 总被引:2,自引:0,他引:2
J. W. Thorpe S. F. Halpin D. G. MacManus G. J. Barker B. E. Kendall D. H. Miller 《Neuroradiology》1994,36(5):388-392
Long repetition time (TR) spin-echo (SE) with T2- or proton density weighting is the sequence of choice to detect the brain lesions of multiple sclerosis (MS). Fast spin-echo (FSE) permits the generation of T2-weighted images with similar contrast to SE but in a fraction of the time. We compared the sensitivity of FSE and SE in the detection of the brain lesions of MS. Six patients with clinically definite MS underwent brain imaging with both dual echo (long TR, long and short echo time (TE) SE and dual echo FSE. The SE and FSE images were first reviewed independently and then compared. A total of 404 lesions was detected on SE and 398 on FSE. Slightly more periventricular lesions were detected using SE than FSE (145 vs 127), whereas more posterior cranial fossa lesions were detected by FSE (77 vs 57). With both SE and FSE the short TE images revealed more lesions than the long echo. These results suggest that FSE could replace SE as the long TR sequence of choice in the investigation of MS. 相似文献
177.
Magnetic resonance angiography (MRA) of the circle of Willis: a prospective comparison with conventional angiography in 54 subjects 总被引:4,自引:0,他引:4
We prospectively correlated the findings of magnetic resonance angiography (MRA) with those of transfemoral four-vessel angiography in 54 patients to investigate the direction of flow within the circle of Willis. Our primary goal was to assess the direction of flow using the size of the vessel and signal intensity, without saturation techniques. Analysis of the circle of Willis, especially the communicating arteries, was performed double-blind by two groups of two radiologists. Three types of arteries were identified: high flow or cross-cerebral circulation, patent and nonvisualised arteries. Cerebral angiography was the standard for comparison between the two methods. MRA did not reveal any arteries invisible on angiography, thus providing a specificity of 100%. The sensitivity of MRA was 89.2% for the anterior and 81.3% for the posterior communicating arteries, and 100% for the anterior, middle and posterior cerebral arteries. MRA was shown to be a useful technique for the assessment of patency of the circle of Willis. 相似文献
178.
Hiroyuki Ishizu Masatoshi Takahashi Yukifumi Kondo Akihiko Kataoka Takashi Nakamura Kuniaki Okada Hiroyuki Masuko Yasunori Nishida Hideaki Ogawa Ryoji Yokoyama Yutaka Kimura 《Surgery today》1997,27(3):285-287
Magnetic resonance cholangiopancreatography (MRCP) was performed in 35 patients to evaluate the feasibility of its use as a postsurgical imaging technique after resection of the pancreas. The surgical procedures performed were: pancreatoduodenectomy in 22 patients, segmental pancreatectomy in 1, distal pancreatectomy in 7, and pyroluspreserving pancreatoduodenectomy in 5. The pancreatic duct was shown in its entirety in 24 of the 35 patients (68.6%) and was partially visualized in 8 patients (22.9%), but the intrahepatic and extrahepatic bile ducts were visualized completely in all patients. Furthermore, MRCP was able to demonstrate lesions in 3 of 6 patients who had shown clinical evidence of recurrence. The visualization of the pancreatic and bile duct system was satisfactory despite anatomical changes brought about by resection of the pancreas. Thus, we conclude that MRCP is an appropriate follow-up screening test for patients with suspected abnormalities of the biliary and pancreatic duct system. 相似文献
179.
I.J. Namer J. Steibel S.J. Piddlesden M. Mohr P. Poulet J. Chambron 《Journal of neuroimmunology》1994,54(1-2)
Two models of demyelinating experimental allergic encephalomyelitis (EAE) were studied on Lewis rats in whom the disease was induced by injections of either (i) lentil-lectine binding myelin glycoproteins plus myelin basic protein (MBP)-specific T cells (36 rats), or (ii) myelin/oligodendrocyte glycoprotein-specific monoclonal antibody plus MBP-specific T cells (16 rats). In our 24 control rats, 20 received MBP-specific T cells only, and four received myelin glycoproteins plus purified protein derivative-specific T cells. The extent of the resulting blood-brain barrier (BBB) permeability, vasogenic oedema and/or demyelination was assessed in vivo using magnetic resonance imaging (MRI) techniques. The results show that in both demyelinating EAE models the disease appeared more quickly, progressed very rapidly and was more severe than when induced with a similar number of MBP-specific T cells alone. Almost all animals developed hypercute EAE, with a very high mortality rate. MRI showed a very intense BBB breakdown and vasogenic oedema in all the normally ‘leaky’ areas of the central nervous system, and focal lesions corresponding to plaque formation in the brain stem or spinal cord near the ‘leaky’ areas. During the 40-day observation period, the rare survivors of this hyperacute form of EAE presented a chronic form of EAE with serious sequelae. Our results demonstrate that the synergistic effect observed between MBP-specific T cells and antibodies to myelin glycoproteins, especially to myelin/oligodendrocyte glycoprotein, does not only induced demyelinating lesions and chronic clinical signs, but is further responsible, via the normally ‘leaky areas’, for the fatal increase of the BBB breakdown and vasogenic oedema of which there are ample acute clinical signs. 相似文献
180.
Michael P. Recht Josef Kramer Cheryl A. Petersilge Joseph Yu Mini Pathria Debra Trudell David J. Sartoris Donald Resnick 《Journal of magnetic resonance imaging : JMRI》1994,4(2):173-177
Although magnetic resonance (MR) images of the glenohumeral joint frequently demonstrate intraarticular fluid, no specific criteria have, to the authors' knowledge, been published that allow accurate assessment of the amount of fluid present. Also, despite the increasing use of MR arthrography of the shoulder, the optimal amount of intra-articular fluid that should be used with this technique has not been determined. The authors progressively distended the glenohumeral joint in six cadaveric shoulder specimens with a dilute gadopentetate dimeglumine solution and obtained MR images after injection of 2, 5, 10, 15, and 20 mL of the solution. The pattern of fluid distribution was evaluated, and these results were then used to estimate the amount of fluid that was present in the glenohumeral joint on MR images of 20 shoulders obtained in 12 asymptomatic volunteers. In 14 of these shoulders, intraarticular fluid was present; however, in none was more than 2 mL evident. Results of the cadaveric study also indicated that 15 mL of intraarticular fluid appears to be the optimal amount for MR arthrography. 相似文献