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21.
目的:探讨头颈部良性神经源性肿瘤在单体素^1H MRS上的表现特点。材料和方法:共收集经单体素。HMRS检查,并经手术病理证实的头颈部神经源性肿瘤14例(神经鞘瘤11例,神经纤维瘤2例,颈动脉体瘤1例)。采用点分析波谱法(PRESS:TE=144ms,14例)和激励回波法(STEAM:TE=30ms,11例)进行。HMRS空间定位,以胆碱和脂质代谢物为标准评价所有肿瘤。波谱图上,胆碱和脂质分别在3.2ppm和0.9—1.4ppm区域识别。结果:采用PRESS后,14例神经源性肿瘤中检测出胆碱代谢物者11例,检出脂质代谢物者6例。胆碱和脂质代谢物同时检出者5例,仅检出胆碱者6例,仅检出脂质者1例,胆碱和脂质均未检出者2例。采用STEAM后,11例肿瘤中检出胆碱代谢物和脂质者分别为3例和8例。结论:头颈部良性神经源性肿瘤的单体素。HMRS表现具有多样性,多数肿瘤以长TEPRESS上胆碱峰的显示为特点,长TEPRESS能较STEAM更好地检出良性神经源性肿瘤内的胆碱代谢物。 相似文献
22.
L. Porto E. Hattingen U. Pilatus M. Kieslich B. Yan D. Schwabe F. E. Zanella H. Lanfermann 《Child's nervous system》2007,23(3):305-314
Background Diagnosis of brainstem lesions in children based on magnetic resonance imaging alone is a challenging problem. Magnetic resonance
spectroscopy (MRS) is a noninvasive technique for spatial characterization of biochemical markers in tissues and gives information
regarding cell membrane proliferation, neuronal damage, and energy metabolism.
Methods We measured the concentrations of biochemical markers in five children with brainstem lesions and evaluated their potential
diagnostic significance. Images and spectra were acquired on a 1.5-T imager. The concentrations of N-acetylaspartate, tetramethylamines (e.g., choline), creatine, phosphocreatine, lactate, and lipids were measured within lesions
located at the brainstem using Point-resolved spectroscopy sequences.
Results Diagnosis based on localized proton spectroscopy included brainstem glioma, brainstem encephalitis, demyelination, dysmyelination
secondary to neurofibromatosis type 1 (NF 1), and possible infection or radiation necrosis. In all but one patient, diagnosis
was confirmed by biopsy or by clinical follow-up.
Conclusions This small sample of patients suggests that MRS is important in the differential diagnosis between proliferative and nonproliferative
lesions in patients without neurofibromatosis. Unfortunately, in cases of NF 1, MRS can have a rather misdiagnosis role. 相似文献
23.
Karina D. TORRALBA Dorothy JOHNSON Francisco P. QUISMORIO 《International journal of rheumatic diseases》2006,9(3):294-297
A 66‐year‐old woman developed firm, painless, slowly growing nodular masses over her elbows, fingers, toes, and left hip over four years. Aspiration of the elbow mass revealed a white chalky material that was shown to be carbonate apatite on infrared spectroscopy and energy dispersive X‐ray spectroscopy. We discuss the classification of tumoral calcinosis and the nature of the calcium deposits. Tumoral calcinosis should be differentiated from tophaceous gout and calcium pyrophosphate dihydrate crystal deposition disease. Polarizing light microscopy and crystal analysis by X‐ray and infrared spectroscopy, electron or X‐ray diffraction will confirm the diagnosis. Secondary causes of tumoral calcinosis should also be excluded. 相似文献
24.
E. Drakaki E. Borisova M. Makropoulou L. Avramov A. A. Serafetinides I. Angelov 《Skin research and technology》2007,13(4):350-359
BACKGROUND/PURPOSE: Laser-induced autofluorescence spectroscopy provides excellent possibilities for medical diagnostics of different tissue pathologies including cancer. However, to create the whole picture of pathological changes, investigators collect spectral information from patients in vivo or they study different tumor models to obtain objective information for fluorescent properties of every kind of healthy and diseased tissue. Therefore, it is very important to find the most appropriate, and close to the human skin, animal samples from the fluorescence point of view, which will allow the extrapolation of the animal data to human spectroscopic diagnostics. METHODS: In the present work, we examined the autofluorescence properties of different animal skin tissues, which are considered as the most common skin models. A nitrogen laser was used as an excitation source. Samples of healthy mouse, chicken and pig skin in vivo and/or ex vivo were studied and were compared with results obtained from investigations of healthy human skin in vivo. RESULTS AND CONCLUSION: Specific features of the recorded spectra are discussed and the possible origin of the obtained fluorescence signals is proposed. Quantitative evaluation of data extrapolation for each skin type is also depicted. 相似文献
25.
MR频谱检测乳酸的脉冲序列优化研究 总被引:1,自引:0,他引:1
目的通过改变一系列脉冲序列参数,以利于乳酸的最佳检测与定量分析。方法制作含乳酸玻璃模型。改变一系列的MR脉冲序列参数,应用点解析频谱序列(point resolved spectroscopy,PRESS)和激励回波序列(stimulated echo acquisition,STEAM)获得乳酸模型的相应频谱。另外,对12例脑病变患者和2例健康志愿者进行磁共振频谱检查,测量出每个波峰的峰高,并绘出序列变化曲线图。结果STEAM各波峰的峰向与PRESS序列一致,但STEAM各峰高均低于同等条件的PRESS峰。随着TE时间的延长,用乳酸模型测出的乳酸峰的峰高一序列曲线图呈波浪状变化,正向双峰在TE=26、270ms时共振波幅达到最大绝对值,负向双峰在TE=135~160ms之间达到最大绝对值。脑病变患者和健康志愿者的扫描结果表明,乳酸峰在优化的序列高于非优化的序列。结论优化的脉冲序列更有利于乳酸的检测与定量分析。 相似文献
26.
27.
嗅神经母细胞瘤(olfactory neuroblastoma,ONB)是外胚层神经上皮源性恶性肿瘤,临床上比较少见,沿嗅神经向上穿越筛板侵犯前颅窝嗅沟区是其特征。影像学表现缺乏特征性,但影像学在其病变定位、恶性程度判断上有一定的应用价值,并需要与其它疾病进行鉴别诊断。 相似文献
28.
目的探讨单蒂横行腹直肌肌皮瓣乳房再造术中Ⅳ区皮瓣的取舍。方法通过16例实施单蒂横行腹直肌肌皮瓣乳房再造术,术中观察皮瓣的皮色、断面出血颜色,并利用近红外血氧监测仪测定皮瓣各区的组织血氧饱和度,决定Ⅳ区皮瓣的取舍。术后观察指标包括术后并发症及美学效果。结果16例中5例Ⅳ皮瓣的肤色正常、断面出血呈鲜红色而非暗红色、组织血氧饱和度不低于Ⅲ区组织血氧饱和度的95%。在接受了保留Ⅳ区皮瓣的单蒂横行腹直肌肌皮瓣乳房再造术后,再造乳房全部成活,无严重术后并发症,患者对再造乳房均很满意。结论近红外血氧无创检测有助于决定Ⅳ区皮瓣的取舍。有选择地实施保留Ⅳ区皮瓣的单蒂横行腹直肌肌皮瓣乳房再造术,可用于大面积胸壁缺损或乳腺尾叶的修复重建。 相似文献
29.
The purpose of this study is to show the spectrum of adjacent organ invasion and to make a brief review of hepatic alveolar hydatid disease (AHD), using CT and MR imaging. We retrospectively reviewed CT and MR images of three patients with various adjacent organ invasions surgically and histologically proven to be AHD. Local invasion to right kidney and adrenal, right hemidiaphragm and lung were detected in one patient, right adrenal in another patient and gall bladder, duodenum, gastric wall and pancreas invasion in the other. AHD may rarely extend to the gall bladder, stomach, duodenum, pancreas, right adrenal and kidney, diaphragm, pleura and lung. The extension of the disease outside the liver is usually encountered in patients with large, peripherally located masses in the advanced stage of the disease. 相似文献
30.
Stephan E. Maier Harvey E. Cline Ferenc A. Jolesz 《Magnetic resonance in medicine》1995,34(5):706-712
Three dimensional (3D) phase contrast angiograms contain velocity data, which is discarded after the reconstruction of the projections. In extension to earlier work on velocity quantification with ungated 2D phase data, this paper shows that a useful estimate of the average velocity and flow rate can be extracted from ungated 3D phase contrast angiograms. Simulations and experiments in a phantom and in vivo were performed. For pulsatile flow and strong spin saturation, an over-estimation of the flow rate at the net in-flow end of the imaging volume and underestimation at the net out-flow end was observed. Imaging at lower RF tip angles yielded flow rates close to the correct value within the entire imaging volume. In contrast to ungated 2D experiments, the flow rates determined by repeated 3D experiments showed no variation. 相似文献