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991.
Beer AJ Hellerhoff P Zimmermann A Mady K Sader R Rummeny EJ Hannig C 《Journal of magnetic resonance imaging : JMRI》2004,20(5):791-797
PURPOSE: To demonstrate the feasibility of dynamic magnetic resonance imaging (MRI) with near-real-time temporal resolution ("real-time MRI") for analyzing the velopharyngeal closure in comparison with multiview videofluoroscopy. MATERIALS AND METHODS: Seven patients (three females and four males, 5-21 years old, mean age=11.3 years) with suspected velopharyngeal insufficiency, and one healthy volunteer were examined with videofluoroscopy and real-time MRI using a turbo-spin-echo (TSE) sequence (TR=170 msec, TE=21 msec, slice thickness=6 mm, six images per second). Imaging was done during phonation in all three image planes. The results were analyzed by two radiologists in comparison with videofluoroscopy as the standard of reference for overall image quality and the pattern of velopharyngeal closure. RESULTS: Real-time MRI correctly depicted the pattern of velopharyngeal closure in correspondence to videofluoroscopy in all cases. Concerning the movement of the pharyngeal walls, real-time MRI falsely depicted a general movement of the dorsal pharyngeal wall in one case, whereas videofluoroscopy showed no movement. In one patient, real-time MRI provided additional information by showing an asymmetric movement of the lateral pharyngeal walls that could not be depicted by videofluoroscopy due to technical limitations. Concerning image quality, the coronal plane was more difficult to evaluate with real-time MRI compared to videofluoroscopy. The axial plane was easier to analyze in real-time MRI compared to videofluoroscopy. CONCLUSION: Real-time MRI has the potential to depict the pattern of velopharyngeal closure in close correlation with videofluoroscopy, and may deliver additional information in selected cases. 相似文献
992.
Validation of the CBF, CBV, and MTT values by perfusion MRI in chronic occlusive cerebrovascular disease: a comparison with 15O-PET 总被引:1,自引:0,他引:1
Kaneko K Kuwabara Y Mihara F Yoshiura T Nakagawa M Tanaka A Sasaki M Koga H Hayashi K Honda H 《Academic radiology》2004,11(5):489-497
RATIONALE AND OBJECTIVES: To evaluate the reliability of cerebral blood flow (CBF), cerebral blood volume (CBV), and mean transit time (MTT) values obtained by deconvolution algorithm perfusion-weighted MR imaging (D-PWI), we compared these values with those obtained by first-moment algorithm perfusion-weighted MR imaging (F-PWI) and 15O-PET. SUBJECTS AND METHODS: Six healthy volunteers and eleven patients with chronic occlusive cerebrovascular disease were studied with both perfusion-weighted MR imaging and 15O-PET, and region-of-interest analyses were performed. Normalization factors for CBF and CBV values obtained by D-PWI were determined as the mean values of 15O-PET divided by those of D-PWI in healthy volunteers. Then these values were used in analyzing the data of the patients. RESULTS: The MTT value obtained by D-PWI was 6.1 +/- 0.5 seconds on the non-occluded side, 6.4 +/- 0.7 seconds on the minimally to moderately stenosed side, and 6.7 +/- 1.2 seconds on the severely stenosed to occluded side. These values were significantly correlated with those obtained by F-PWI (r = 0.83; P < .001), and with those obtained by 15O-PET (r = 0.78; P < .05). However, the CBF and CBV values obtained by D-PWI did not correlate with those obtained by 15O-PET. CONCLUSION: MTT values obtained by D-PWI were reliable parameters of cerebral hemodynamics, but the CBF and CBV values obtained by D-PWI were not always reliable. 相似文献
993.
Yun Sun Choi Kyung Tai Lee Heung Sik Kang Eun Kyung Kim 《Korean journal of radiology》2004,5(4):274-279
Objective
To evaluate the MR imaging findings of painful type II accessory navicular bone and to correlate these with the surgical and pathologic findings.Materials and Methods
The MR images of 17 patients with medial foot pain and surgically proven type II accessory navicular abnormalities were reviewed. The changes of signal intensity in the accessory navicular, synchondrosis and adjacent soft tissue, the presence of synchondrosis widening, and posterior tibial tendon (PTT) pathology on the T1-weighted and fat-suppressed T2-weighted images were analyzed. The MR imaging findings were compared with the surgical and pathologic findings.Results
The fat-suppressed T2-weighted images showed high signal intensity in the accessory navicular bones and synchondroses in all patients, and in the soft tissue in 11 (64.7%) of the 17 patients, as well as synchondrosis widening in 3 (17.6%) of the 17 patients. The MR images showed tendon pathology in 12 (75%) of the 16 patients with PTT dysfunction at surgery. The pathologic findings of 16 surgical specimens included areas of osteonecrosis with granulomatous inflammation, fibrosis and destruction of the cartilage cap.Conclusion
The MR imaging findings of painful type II accessory navicular bone are a persistent edema pattern in the accessory navicular bone and within the synchondrosis, indicating osteonecrosis, inflammation and destruction of the cartilage cap. Posterior tibial tendon dysfunction was clinically evident in most patients. 相似文献994.
Kil-Ho Cho Sung Moon Lee Young Hwan Lee Kyung Jin Suh Sung Moon Kim Myung Jin Shin Han Won Jang 《Korean journal of radiology》2004,5(4):280-286
Objective
We wished to report on the MRI findings of non-infectious ischiogluteal bursitis.Materials and Methods
The MRI findings of 17 confirmed cases of non-infectious ischiogluteal bursitis were analyzed: four out of the 17 cases were confirmed with surgery, and the remaining 13 cases were confirmed with MRI plus the clinical data.Results
The enlarged bursae were located deep to the gluteus muscles and postero-inferior to the ischial tuberosity. The superior ends of the bursal sacs abutted to the infero-medial aspect of the ischial tuberosity. The signal intensity within the enlarged bursa on T1-weighted image (WI) was hypo-intense in three cases (3/17, 17.6%), iso-intense in 10 cases (10/17, 58.9%), and hyper-intense in four cases (4/17, 23.5%) in comparison to that of surrounding muscles. The bursal sac appeared homogeneous in 13 patients (13/17, 76.5%) and heterogeneous in the remaining four patients (4/17, 23.5%) on T1-WI. On T2-WI, the bursa was hyper-intense in all cases (17/17, 100%); it was heterogeneous in 10 cases and homogeneous in seven cases. The heterogeneity was variable depending on the degree of the blood-fluid levels and the septae within the bursae. With contrast enhancement, the inner wall of the bursae was smooth (5/17 cases), and irregular (12/17 cases) because of the synovial proliferation and septation.Conclusion
Ischiogluteal bursitis can be diagnosed with MRI by its characteristic location and cystic appearance. 相似文献995.
Tokuo?KasaiEmail author E.?Gordon?DePuey Arshad?Ali?Shah 《Journal of nuclear cardiology》2004,11(1):32-37
OBJECTIVES: Septal wall motion abnormalities are frequently observed in patients with left bundle branch block (LBBB). However, septal wall thickening in LBBB patients has not been thoroughly evaluated. METHODS AND RESULTS: To investigate the relationship between septal wall motion and wall thickening, we studied 31 normal control subjects, 24 LBBB patients with normal wall motion (LBBB-NWM), and 24 LBBB patients with septal dyssynchrony (LBBB-SDS), all with a low likelihood (<15%) of coronary artery disease. The septal and lateral quadrants of the left ventricle were analyzed in stress 8-frame gated technetium 99m sestamibi tomograms. The percent wall thickening was calculated by use of a 25-segment polar map with the p-FAST software program by two independent methods: the regional count density increase from end diastole to end systole (CD method) and the geometric increase in the distance between the 50% thresholded endocardial and epicardial borders from end diastole to end systole (GD method). In addition, the ratio of septal/lateral percent wall thickening was calculated. The relative septal wall thickening in the entire LBBB population was decreased as compared with the normal control subjects (0.35 +/- 0.37 vs 0.81 +/- 0.17, P <.001). Decreased wall thickening was observed in not only LBBB-SDS patients but also to a lesser degree in LBBB-NWM patients (0.12 +/- 0.35, P <.001; 0.57 +/- 0.24, P =.005, respectively). This abnormality was most apparent when the CD method was used. CONCLUSIONS: Septal wall thickening is decreased in patients with LBBB even with normal wall motion. LBBB per se may compromise septal wall thickening, and dyssynchronous wall motion results in further deterioration of wall thickening. 相似文献
996.
Combined quantitative dynamic contrast-enhanced MR imaging and (1)H MR spectroscopic imaging of human prostate cancer 总被引:3,自引:0,他引:3
van Dorsten FA van der Graaf M Engelbrecht MR van Leenders GJ Verhofstad A Rijpkema M de la Rosette JJ Barentsz JO Heerschap A 《Journal of magnetic resonance imaging : JMRI》2004,20(2):279-287
PURPOSE: To differentiate prostate carcinoma from healthy peripheral zone and central gland using quantitative dynamic contrast-enhanced (DCE) magnetic resonance (MR) imaging and two-dimensional (1)H MR spectroscopic imaging (MRSI) combined into one clinical protocol. MATERIALS AND METHODS: Twenty-three prostate cancer patients were studied with a combined DCE-MRI and MRSI protocol. Cancer regions were localized by histopathology of whole mount sections after radical prostatectomy. Pharmacokinetic modeling parameters, K(trans) and k(ep), as well as the relative levels of the prostate metabolites citrate, choline, and creatine, were determined in cancer, healthy peripheral zone (PZ), and in central gland (CG). RESULTS: K(trans) and k(ep) were higher (P < 0.05) in cancer and in CG than in normal PZ. The (choline + creatine)/citrate ratio was elevated in cancer compared to the PZ and CG (P < 0.05). While a (choline + creatine)/citrate ratio above 0.68 was found to be a reliable indicator of cancer, elevated K(trans) was only a reliable cancer indicator in the diagnosis of individual patients. K(trans) and (choline + creatine)/citrate ratios in cancer were poorly correlated (Pearson r(2) = 0.07), and thus microvascular and metabolic abnormalities may have complementary value in cancer diagnosis. CONCLUSION: The combination of high-resolution spatio-vascular information from dynamic MRI and metabolic information from MRSI has excellent potential for improved localization and characterization of prostate cancer in a clinical setting. J. Magn. Reson. Imaging 2004;20:279-287. Copyright 2004 Wiley-Liss, Inc. 相似文献
997.
Ki Yeol Lee Taik-Kun Kim Minkyu Park Sungyu Ko In Chan Song Ik-Hwan Cho 《Korean journal of radiology》2004,5(2):96-101
Objective
This study was designed to compare three different measures of the elderly human brain; the magnetization transfer ratio (MTR) histogram, the percentage of brain parenchymal volume, and the volume of T2 hyperintense areas in terms of correlations with the study subjects'' neurocognitive performance.Materials and Methods
Thirty-five healthy community-dwelling elderly volunteers aged 60-82 years underwent dual fast spin-echo (FSE) imaging and magnetization transfer imaging. A semi-automated technique was used to generate the MTR histogram, the brain parenchymal volume, and the T2 lesion volume. The subjects'' neurocognitive performance was assessed by using the Korean-Mini Mental State Examination (K-MMSE) and additional tests. The peak height of the MTR (PHMTR), the percentage of brain parenchymal volume (PBV), and the normalized T2 lesion volume (T2LV) were compared between the normal group (Z score on the K-MMSE ≥ -2, n=23) and the mild cognitive impairment group (Z score on the K-MMSE < -2, n=12), and these parameters were correlated with age and various neurocognitive performance scores.Results
The PHMTR was significantly lower in the cognitively impaired subjects than the PHMTR in the normal subjects (p = 0.005). The PBV scores were lower in the cognitively impaired subjects than in the normal subjects (p = 0.02). The T2LV scores were significantly higher in the cognitively impaired subjects (p = 0.01). An inverse correlation was found between the PHMTR and T2LV (r = -0.747, p < 0.001), and also between the PBV and T2LV (r = -0.823, p < 0.001). A positive correlation was observed between the PHMTR and the PBV (r = 0.846, p < 0.001). Scores on the various neurocognitive tests were positively correlated with the PHMTR (6 of 7 items) and the PBV (5 of 7 items), and they were negatively correlated with the T2LV (5 of 7 items).Conclusion
Our findings of a correlation among the PBV, the T2LV, and the PHMTR suggest that MTR histograms and the PBV and T2LV can be used as a reliable method and valid statistical tool, respectively, for quantifying the total lesion burden in an aging brain. 相似文献998.
Sunseob Choi Haiying Liu Tae Beom Shin Jin Hwa Lee Seong Kuk Yoon Jong Young Oh Young-Il Lee 《Korean journal of radiology》2004,5(3):143-148
Objective
The aim of this study was to examine the feasibility of perfusion imaging of the brain using the Z-score and subtraction dynamic images obtained from susceptibility contrast MR images.Materials and Methods
Five patients, each with a normal MRI, Moya-moya, a middle cerebral artery occlusion, post-trauma syndrome, and a metastatic brain tumor, were selected for a presentation. A susceptibility-contrast echo-planar image after a routine MRI was taken as the source image with a rapid manual injection of 0.1 mmol/kg of Gd-DTPA. The inflow and washout patterns were observed from the time-signal intensity curve of the serial scans using the standard program of an MRI machine. The repeated Z-score images of the peak and late phases were made using the threshold Z-score values between 1.4 and 2.0 in four to five studies of the pre-contrast, peak, and late phases. Dynamic subtraction images were produced by subtracting sequential post-contrast images from a pre-contrast image and coloring these images using a pseudocolor mapping method.Results
In the diseases with perfusion abnormalities, the Z-score images revealed information about the degree of perfusion during the peak and late phases. However, the quality varied with the Z-score threshold and the studies selected in a group. The dynamic subtraction images were of sufficient quality with no background noise and more clearly illustrated the temporal changes in perfusion and delayed perfusion.Conclusion
The Z-scores and dynamic subtraction images illustrated the degree of perfusion and sequential changes in the pattern of perfusion, respectively. These images can be used as a new complimentary method for observing the perfusion patterns in brain diseases. 相似文献999.
Soo-Jung Choi Myung Jin Shin Sung Moon Kim Sang-Jin Bae 《Korean journal of radiology》2004,5(4):219-224
Objective
We wished to evaluate the incidence of non-contiguous spinal injury in the cervicothoracic junction (CTJ) or the upper thoracic spines on cervical spinal MR images in the patients with cervical spinal injuries.Materials and Methods
Seventy-five cervical spine MR imagings for acute cervical spinal injury were retrospectively reviewed (58 men and 17 women, mean age: 35.3, range: 18-81 years). They were divided into three groups based on the mechanism of injury; axial compression, hyperflexion or hyperextension injury, according to the findings on the MR and CT images. On cervical spine MR images, we evaluated the presence of non-contiguous spinal injury in the CTJ or upper thoracic spine with regard to the presence of marrow contusion or fracture, ligament injury, traumatic disc herniation and spinal cord injury.Results
Twenty-one cases (28%) showed CTJ or upper thoracic spinal injuries (C7-T5) on cervical spinal MR images that were separated from the cervical spinal injuries. Seven of 21 cases revealed overt fractures in the CTJs or upper thoracic spines. Ligament injury in these regions was found in three cases. Traumatic disc herniation and spinal cord injury in these regions were shown in one and two cases, respectively. The incidence of the non-contiguous spinal injuries in CTJ or upper thoracic spines was higher in the axial compression injury group (35.3%) than in the hyperflexion injury group (26.9%) or the hyperextension (25%) injury group. However, there was no statistical significance (p > 0.05).Conclusion
Cervical spinal MR revealed non-contiguous CTJ or upper thoracic spinal injuries in 28% of the patients with cervical spinal injury. The mechanism of cervical spinal injury did not significantly affect the incidence of the non-contiguous CTJ or upper thoracic spinal injury. 相似文献1000.
In acetabular dysplasia, more vertical orientation of the acetabular component is often used to minimize the superolateral bone grafting. This study was designed to determine the effects of vertical orientation of the cup on the stability and polyethylene wear of the acetabular component in uncemented total hip arthroplasty (THA). Three-dimensional finite element models of the hemipelvis with dysplastic acetabulum were developed. Metal-backed hemispherical cups were placed in the true acetabulum with abduction angles of 35, 45, 55, and 65 degrees. It was found that more vertical orientation of the cup was associated with larger relative motion of the metal shell between the acetabulum and metal shell. Furthermore, tilting and torsional shear stresses in the model of the cup abduction angle of 65 degrees were found to be 1.7 times larger than that in the model with 35 degrees at the bone-metal shell interface. More vertically oriented cups caused larger contact stresses at the articulating surfaces of the polyethylene liners. The results suggest that the abduction angle of the acetabular component significantly influences cup loosening and polyethylene wear in THA. 相似文献