河南汉族人群亚甲基四氢叶酸还原酶基因多态性

目的了解河南汉族人亚甲基四氢叶酸还原酶(methylenetetrahydrofolate reductase,MTHFR)基因的分布特点。方法应用PCR-RFLP技术对500例健康个体的MTHFRC677T基因进行基因多态性分析,并结合文献进行了不同种族间的分析比较。结果河南汉族人群中MTHFRC677T突变纯合子TT型频率为32.8%,突变杂合子CT型频率为34.6%,野生型CC型频率为32.6%,T等位基因频率51.1%,与其他种族相比较,MTHFRC677T基因型在中国河南汉族正常人群中的分布与其他人群中的分布差异显著。结论MTHFRC677T基因多态性在不同种族间分布存在着明显的差异。     

海南省中医护理队伍现状调查分析

目的获取海南省中医护理队伍现状量化数据,为相关部门制定政策提供依据.方法采用自制问卷,对海南省14所中医院护理队伍的人力资源现状、护理工作模式及参加继续护理学教育等情况进行调查.结果中医护理队伍较年轻(20～39岁,占74.00%,护龄＜10年者占58.96%);学历以中专为主(占91.83%);职称以护师为主(占63.00%),高、中级职称主要集中在省级中医院;推行整体护理模式病区仅占44.44%(16/36);参加继续护理学教育及熟练掌握电脑操作者分别为21.71%、5.98%.结论海南省中医护理队伍中高等学历及职称人员紧缺,且分布不均;继续护理学教育机会少,护理模式及管理工作滞后,相关部门应引起高度重视,尽快采取对策,以促进海南省中医护理的发展.     

Application of Nonlinear Optical Microscopic Imaging Technology for Quality Assessment of Donor Kidneys

Background

Nonlinear optical microscopic (NLOM) imaging technique shows its high resolution imaging features in histocytology. The purpose of this study was to investigate NLOM imaging technique as a useful tool for a donor kidney quality assessment.

232例湖北地区泌尿系结石红外光谱成分分析

目的：分析湖北地区泌尿系结石化学成分的构成,为本地区结石的防治提供依据。方法：采用结石红外光谱自动分析系统对2011年11月～2012年8月期间收集到的湖北地区泌尿系结石232例进行成分分析。结果：232例结石中,各成分的检出率为：一水草酸钙（COM）85．34％,二水草酸钙（COD）62．93％,碳酸磷灰石（CA）24．14％,无水尿酸（UA）12．93％,二水磷酸氢钙（PH）4．31％,磷酸铵镁（MAP）6．90％,黄嘌呤1．29％,胱氨酸（CYS）1．29％,方解石0．86％,尿酸铵（AU）0．86％。含草酸钙成分结石86．21％,含磷酸钙成分结石28．45％,含磷酸铵镁成分结石6．90％,含尿酸成分结石13．79％,含胱氨酸成分结石1．29％。混合成分结石181例（78．02％）,尿路结石发病男性多于女性,男女比例为3．14：1。结论：湖北地区泌尿系结石以混合性结石为主,COM检出率最高,其次为COD。结石成分分析对于结石的防治有重要意义。     

Cross-Cultural Adaptation,Reliability, and Validity of the Chinese Version of the Tampa Scale for Kinesiophobia-11 Among Patients Who Have Undergone Total Knee Arthroplasty

BackgroundThe shortened version of the Tampa Scale for Kinesiophobia (TSK-11) has been well characterized in the literature. However, to the best of our knowledge, no previous studies have evaluated the reliability and validity of the TSK-11 for Chinese-speaking patients who have undergone total knee arthroplasty (TKA). Thus, the objectives of this study were to translate and adapt the TSK-11 cross-culturally into Chinese and to evaluate its reliability and validity in a sample of Chinese TKA patients.MethodsThe TSK-11 was translated and cross-culturally adapted into Chinese according to the international guidelines for the cross-cultural adaptation of self-report measures. The Chinese version of TSK-11 was administered to 254 patients following their TKA, along with the Fear-Avoidance Beliefs Questionnaire, Pain Catastrophizing Scale, Numerical Rating Scale, and 12-Item Short Form Health Survey. Psychometric testing included internal consistency, test-retest reliability, floor and ceiling effects, construct validity, and convergent validity.ResultsA high completion rate of 95.8% with no floor or ceiling effects was noted in the Chinese version of the TSK-11. The questionnaire also showed good internal consistency (Cronbach’s α = 0.883) and test-retest reliability (intraclass correlation coefficient = 0.798). Construct validity was assessed by exploratory factor analysis, and 3 factors were extracted that accounted for 65.2% of the variance. Convergent validity was confirmed by significant Pearson correlations between the Chinese version of the TSK-11 and the Pain Catastrophizing Scale (r = 0.751), Fear-Avoidance Beliefs Questionnaire (r = 0.719) and VAS (r = 0.450), as well as the 12-Item Short Form Health Survey subdomains Bodily Pain (r = ?0.391), Mental Health (r = ?0.356), Physical Functioning (r = ?0.339), Role-Emotional (r = ?0.317), and Role-Physical (r = ?0.277).ConclusionThe Chinese version of the TSK-11 demonstrated satisfactory acceptability, reliability, and validity; therefore, it can be used in clinical practice and research for assessing kinesiophobia in Chinese patients after TKA.     

Chevron osteotomy versus scarf osteotomy for hallux valgus correction: A meta-analysis

BackgroundThis study intended to investigate the optimal surgical strategy in hallux valgus (HV), and to provide a basis for clinical treatment of HV.MethodsStudies related to chevron osteotomy and scarf osteotomy for HV were enrolled from online databases. Hallux valgus angle (HVA) was the main outcome variable. Enrolled studies included posttreatment data for intermetatarsal angle (IMA), American Orthopaedic Foot & Ankle Society (AOFAS) score, and complications. A random-effects model was applied for significant heterogeneity. Otherwise, a fixed-effects model was used. Heterogeneity was assessed with Q test and I² statistics. Publication bias was evaluated with Egger's test. Based on the influence of weighted mean difference values or odds ratios, a sensitivity analysis was performed.ResultsFour studies including 384 subjects were evaluated to determine the optimal surgical strategy for HV. There was no statistically significant difference between chevron and scarf groups for HVA, IMA, AOFAS score, and complication rates. Sensitivity analysis showed good stability. The likelihood of publication bias was small.ConclusionThe effects of chevron osteotomy and scarf osteotomy for HV are comparable. Chevron osteotomy is less technically demanding.     

Cauliflower-like Neoplasm of Duodenal Papilla in a Liver Transplant Recipient: What Should We Think and Do? A Case Report

Background

With the continuous improvement of liver transplantation technology, the survival rate of liver transplantation has been improved, but recurrent or de novo malignancy remains one of the major factors affecting the long-term survival of liver transplant recipients.

Simple Analysis of the Computed Tomography Features of Gastric Schwannoma

ObjectiveThe objective of this study was to assess the computed tomography (CT) findings of gastric schwannoma (GS) and identify the difference between large (> 5 cm) and small (≤ 5 cm) GS.Materials and MethodsCT findings of 38 pathologically proven cases of GSs were retrospectively reviewed. The CT evaluation of GS included categorical variables (location, contour, growth pattern, enhancement pattern, necrosis, ulceration, calcification, and lymph nodes) and continuous variables (size, CT value of 3 phases, and enhancement degree). The lesion was divided into 2 groups (large [> 5 cm] and small [≤ 5 cm] GS) according to the tumor size. The Fisher exact test was used for categorical variables and the Student t or Mann-Whitney U test for continuous variables.ResultsOf the 38 patients, there were 32 women and 6 men. The median age was 54.5 years (range 39–79). Most of patients (65.8%, [25 of 38]) had nonspecific gastrointestinal symptoms such as abdominal or gastric pain, fullness and discomfort, bleeding, and melena. The tumors were mainly located in the stomach body (71.1% [27 of 38]), and the mean diameter was 3.7 cm (range 1.5 cm-10.3 cm), of which included large (> 5 cm) (n = 8) and small (≤ 5 cm) (n = 30). All of the GSs were benign, 9 of whom had palpable perigastric lymph nodes, which confirmed by pathology for the reactive inflammatory hyperplasia. Growth pattern, pattern of enhancement, necrosis, calcification, surface ulceration, and lymph node in the CT images were found to be significant variables for differentiating large (> 5 cm) and small (≤ 5 cm) GS (P < .05).ConclusionGSs were predominantly located at the gastric body and occurred most frequently in women between the ages of 40–70 years, and showed gradual enhancement after contrast enhancement. Palpable perigastric lymph nodes could not be considered as malignant factor of GS. There 7 computed CT criteria are significant difference between large (> 5 cm) and small (≤ 5 cm) GS.