大骨节病区与非病区儿童发中硼,锗元素含量变化初探

初步调查了大骨节病区与非病区儿童发中硼,锗元素含量的变化及与补硒的关系。方法：用ＩＣＰ－ＭＳ法测定陕西省彬县大骨节病区和非病区儿童５组１５０名６－１４岁男童发中硼,锗元素含量。结果：硼、锗元素依非病区,病区健康和大骨节病必而递减。     

羧乙基锗倍半氧化物对大鼠肺缺血再灌注损伤的保护作用

采用 Wistar大鼠原位肺缺血再灌注损伤模型 ,测定再灌注后左肺动脉压、左肺湿干比质量值 ,肺组织中丙二醛 (MDA)含量 ,超氧化物歧化酶 (SOD)及 ATPase活性。发现预防性静脉注射羧乙基锗倍半氧化物 CGS(5 0 mg/kg)后 ,与对照组和假手术组相比较 ,可显著降低再灌注肺组织中 MDA、左肺动脉压及肺湿干质量比值(F =6 .37,q =8.98,P<0 .0 1;F=3.85 ,q=4.2 1,P<0 .0 5 ;F=4.0 6 ,q=5 .38,P<0 .0 0 1) ;明显提高肺组织中SOD及 ATPase活性 (F=6 .37,q=10 .2 1,P<0 .0 0 1;F=6 .37,q=8.6 4,P<0 .0 5 )。认为 CGS对大鼠实验性肺缺血再灌注损伤具有保护作用。     

三氧化二镍诱导人肺成纤维细胞恶性转化的实验研究

在体外用不同浓度的Ni2O3多次处理人肺成纤维细胞(HLF),并进行转化细胞的恶性鉴定--刀豆凝集素A(ConA)试验和软琼脂细胞培养试验.发现Ni2O3可诱导HLF细胞恶性转化,转化细胞生长速度加快,排列紊乱,失去接触抑制,呈交叉重叠生长,在实验浓度范围内,转化率呈剂量-反应关系.转化细胞可被低浓度ConA凝集,并在软琼脂内生长.提示Ni2O3有较强的诱导人肺成纤维细胞恶性转化的能力,具有致癌性.     

EANM guidelines for PET-CT and PET-MR routine quality control

We present guidelines by the European Association of Nuclear Medicine (EANM) for routine quality control (QC) of PET-CT and PET-MR systems. These guidelines are partially based on the current EANM guidelines for routine quality control of Nuclear Medicine instrumentation but focus more on the inherent multimodal aspect of the current, state-of-the-art PET-CT and PET-MR scanners. We briefly discuss the regulatory context put forward by the International Electrotechnical Commission (IEC) and European Commission (EC) and consider relevant guidelines and recommendations by other societies and professional organizations. As such, a comprehensive overview of recommended quality control procedures is provided to ensure the optimal operational status of a PET system, integrated with either a CT or MR system. In doing so, we also discuss the rationale of the different tests, advice on the frequency of each test and present the relevant MR and CT tests for an integrated system. In addition, we recommend a scheme of preventive actions to avoid QC tests from drifting out of the predefined range of acceptable performance values such that an optimal performance of the PET system is maintained for routine clinical use.