葡萄糖酸锗对大白鼠内分泌腺的影响

应用放射免疫法及透射电镜研究葡萄糖酸锗对雌性大白鼠内分泌腺的影响。大鼠经腹腔注射葡萄糖酸锗50mg/kg·d,连续6天,放免测定血清的激素值,实验组的生长激素(GH)显著增高(P<0.01),促甲状腺激素(TSH)、三碘甲状腺原氨酸(T_3)和四碘甲状腺原氨酸(T_4)均显著降低(P<0.01),而卵泡刺激素(FSH)、黄体生成素(LH)和皮质醇均无明显变化。透射电镜下可见脑垂体远侧部生长激素细胞,呈分泌释放功能旺盛相。促甲状腺激素细胞呈分泌释放功能不活跃状态。结果表明,葡萄糖酸锗具有刺激生长激素细胞的分泌和抑制促甲状腺激素细胞和甲状腺滤泡上皮细胞的分泌。     

大骨节病区与非病区儿童发中硼,锗元素含量变化初探

初步调查了大骨节病区与非病区儿童发中硼,锗元素含量的变化及与补硒的关系。方法：用ＩＣＰ－ＭＳ法测定陕西省彬县大骨节病区和非病区儿童５组１５０名６－１４岁男童发中硼,锗元素含量。结果：硼、锗元素依非病区,病区健康和大骨节病必而递减。     

羧乙基锗倍半氧化物对大鼠肺缺血再灌注损伤的保护作用

采用 Wistar大鼠原位肺缺血再灌注损伤模型 ,测定再灌注后左肺动脉压、左肺湿干比质量值 ,肺组织中丙二醛 (MDA)含量 ,超氧化物歧化酶 (SOD)及 ATPase活性。发现预防性静脉注射羧乙基锗倍半氧化物 CGS(5 0 mg/kg)后 ,与对照组和假手术组相比较 ,可显著降低再灌注肺组织中 MDA、左肺动脉压及肺湿干质量比值(F =6 .37,q =8.98,P<0 .0 1;F=3.85 ,q=4.2 1,P<0 .0 5 ;F=4.0 6 ,q=5 .38,P<0 .0 0 1) ;明显提高肺组织中SOD及 ATPase活性 (F=6 .37,q=10 .2 1,P<0 .0 0 1;F=6 .37,q=8.6 4,P<0 .0 5 )。认为 CGS对大鼠实验性肺缺血再灌注损伤具有保护作用。     

EANM guidelines for PET-CT and PET-MR routine quality control

We present guidelines by the European Association of Nuclear Medicine (EANM) for routine quality control (QC) of PET-CT and PET-MR systems. These guidelines are partially based on the current EANM guidelines for routine quality control of Nuclear Medicine instrumentation but focus more on the inherent multimodal aspect of the current, state-of-the-art PET-CT and PET-MR scanners. We briefly discuss the regulatory context put forward by the International Electrotechnical Commission (IEC) and European Commission (EC) and consider relevant guidelines and recommendations by other societies and professional organizations. As such, a comprehensive overview of recommended quality control procedures is provided to ensure the optimal operational status of a PET system, integrated with either a CT or MR system. In doing so, we also discuss the rationale of the different tests, advice on the frequency of each test and present the relevant MR and CT tests for an integrated system. In addition, we recommend a scheme of preventive actions to avoid QC tests from drifting out of the predefined range of acceptable performance values such that an optimal performance of the PET system is maintained for routine clinical use.