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991.
目的:探讨解剖Y型钢板的临床应用价值。方法:报告36例解剖Y型钢板内固定肱骨远端粉碎性骨折,进行临床分析讨论,其中列,女8例,平均年龄36.8岁。36例中均行肘后标准切口尽骨鹰嘴截骨暴整个肱骨远端,Y型钢板、螺钉内固定。结果:本组随访1~5年,其中优良率86.2%。结论:解剖Y型钢板治疗治疗肱骨远端粉碎骨折,效果确切,术后有利早期活动关节,减少并发症。 相似文献
992.
目的:比较电灼治疗前后女性生殖道湿疣的免疫状态变化,了解患者其免疫功能在湿疣发展中的作用。方法:采用流式细胞技术及比浊法对45 例生殖道湿疣及30 例正常妇女的血淋巴细胞亚群及血清免疫球蛋白和补体进行检测。结果:湿疣者 C D3 、 C D4 、 C D4/ C D8 及 Ig A、 C3 水平低于正常对照组,治疗后无复发者12 例的5 项指标比治疗前升高,而复发者33例则无变化。结论:免疫功能在湿疣的发生发展中起关键作用,电灼等治疗可刺激机体的免疫功能。 相似文献
993.
闫英 《中山大学学报(医学科学版)》1999,(Z1)
目的:通过对颞下颌关节紊乱病(TMD) 的临床表现及咬合板治疗的疗效进行分析,探讨TMD 的最佳治疗时机。方法:对156 例经咬合板治疗的TMD患者就诊时间及治疗2 个月后治疗效果做分类统计分析。结果:治疗2 个月后疼痛、弹响及张口受限的总治愈率分别为81.4% 、49.0% 和81.5% 。其中于发病4 周内就诊的患者治愈率分别为93.2% 、77.3% 和93.2% ,于4 周后就诊的患者治愈率分别为73.9% 、40.8 % 和30.0 % ,两组差异显著( 弹响及张口受限, P< 0.01,疼痛P<0.05)。结论:TMD在发病4 周内进行咬合板治疗效果满意。 相似文献
994.
目的:探讨反义BCR和ABL融合基因(BCR/ABL融合基因)寡核苷酸体外抑制K562细胞的作用及机制。方法:采用K562细胞培养,观察反义BCR/ABL寡核苷酸体外对K562细胞数、台盼蓝拒染率及克隆形成等的影响。结果:经反义BCR/ABL寡核苷酸b3a2(ASb3a2)处理后培养8d的K562克隆抑制率达6069%,液体培养中细胞数从24h开始较对照组减少,细胞存活率从8h开始即较对照组明显下降,BCR/ABL寡核苷酸b2a2(ASb2a2)及无义寡核苷酸对K562细胞数和存活率无明显影响;3种寡核苷酸对HL60细胞数和存活率也无影响。结论:ASb3a2对K562细胞有序列特异性的抑制作用。ASb3a2的这种抑制作用可能在于它诱导K562细胞的凋亡。 相似文献
995.
目的:观察银杏叶总黄酮(TFGb)抗心肌缺血的作用。方法:采用结扎家兔冠状动脉前降支造成急性心肌梗塞的病理模型,用心电图、血清磷酸肌酸激酶活性和梗死面积评价TFGb对心肌缺血的保护作用。结果:TFGb(167mg·kg-1·d-1,ip,连续用药14d)可明显降低心肌梗塞兔EKG中ST段异常抬高的总幅度以及病理性Q波的出现数;并显著抑制心肌组织磷酸肌酸激酶释放。硝基四氮唑蓝染色显示,预先用TFGb可使心肌梗塞范围明显缩小。结论:TFGb对心肌缺血性损伤具有保护作用 相似文献
996.
用伊曲康唑短程间歇冲击疗法治疗甲真菌病54例(指甲真菌病26例,趾甲真菌病28例),并随访9个月。结果显示:患者指甲临床治愈率为885%,真菌学治愈率为961%;趾甲临床治愈率为821%,真菌学治愈率为961%;仅有74%的患者出现恶心、胃肠道不适等轻微副作用。本疗法疗效高、副作用小和安全性好 相似文献
997.
Multisystemic Treatment of Substance-Abusing and -Dependent Delinquents: Outcomes,Treatment Fidelity,and Transportability 总被引:3,自引:0,他引:3
The effectiveness and transportability of multisystemic therapy (MST) were examined in a study that included 118 juvenile offenders meeting DSM-III-R criteria for substance abuse or dependence and their families. Participants were randomly assigned to receive MST versus usual community services. Outcome measures assessed drug use, criminal activity, and days in out-of-home placement at posttreatment (T2) and at a 6-month posttreatment follow-up (T3); also treatment adherence was examined from multiple perspectives (i.e., caregiver, youth, and therapist). MST reduced alcohol, marijuana, and other drug use at T2 and total days in out-of-home placement by 50% at T3. Reductions in criminal activity, however, were not as large as have been obtained previously for MST. Examination of treatment adherence measures suggests that the modest results of MST were due, at least in part, to difficulty in transporting this complex treatment model from the direct control of its developers. Increased emphasis on quality assurance mechanisms to enhance treatment fidelity may help overcome barriers to transportability. 相似文献
998.
Pseudoaneurysm of the superficial femoral artery following accidental trauma: result of treatment by percutaneous stent-graft placement 总被引:4,自引:0,他引:4
Accidental trauma frequently involves the extremities, and can extend to involve their blood supply, causing exsanguinating
hemorrhage and pseudoaneurysm in the involved blood vessel. This is traditionally managed by surgical repair. We report a
case in which control of life-threatening hemorrhage and exclusion of a large, post-traumatic pseudoaneurysm in the superficial
femoral artery was performed by a commercially available stent-graft, without complication. This treatment method may be a
safe and effective alternative to surgery in selected patients.
Received: 10 February 1998; Revision received: 31 March 1998; Accepted: 20 April 1998 相似文献
999.
Percutaneous endoscopic gastrostomy in burn patients 总被引:2,自引:0,他引:2
Background: Prolonged enteral feedings are required occasionally in seriously burned individuals. We have employed percutaneous endoscopic
gastrostomy (PEG) in selected patients who require particularly prolonged access, thus prompting this review.
Methods: The PEG procedure was performed under general anesthesia in combination with another surgical procedure using a variety of
commercially available needle and guidewire kits in 14 patients.
Results: These 14 patients had an average age of 55.2 ± 6.6 years and a burn involving 38 ± 8% of the body surface. Eleven of these
patients had suffered an inhalation injury. The tubes were placed an average of 57 ± 10.5 days after injury through unburned
and unharvested skin in four patients (28%), healed donor sites in five patients (35%), healed burn in one patient (1%), and
grafted burn in four patients (28%). One patient, whose catheter was placed through a grafted fascial excision, developed
moderate local wound erosion. Tubes were known to have been left in place as long as 155 days. However, most were removed
in rehabilitation hospitals, and we were unable to determine how long most were left in place. We are unaware of any problems
with the tubes occurring after discharge from the acute care setting.
Conclusions: In selected patients, PEG can provide more comfortable access for prolonged enteral feedings than nasogastric tubes and can
be placed with minimal morbidity.
Received: 29 March 1998/Accepted: 1 August 1998 相似文献
1000.
Holliday MA 《Pediatric nephrology (Berlin, Germany)》1999,13(9):989-995
This review highlights characteristics of extracellular fluid (ECF) that are often overlooked. ECF has, in addition to plasma
and interstitial fluid (ISF) surrounding cells, a third large compartment, the ISF of skin and connective tissue. This acts
as a reservoir that gives up ECF to plasma volume (PV) in order to sustain circulation in the event of either shock or dehydration.
While Starling forces drive filtration, ECF is returned to PV more by lymph and less by Starling forces than previously appreciated.
Lymph return to PV is dependent on physical activity and muscle contraction to overcome gravity. Regional change in metabolic
rate alters the need for oxygen and nutrients that is met by a regional increase in capillary blood flow. Blood flow is controlled
by vasoactive compounds released in response to a drop in PO2; these relax capillary smooth muscle to increase blood flow and delivery of oxygen and nutrients. Plasma proteins, including
albumin, are filtered into the interstitium through larger pores than those filtering ECF. The rate of protein filtration
is set by size and charge of these larger endothelial pores and by size and charge of proteins. Charge of these pores, hence
albumin permeability, is regulated by many of the same vasoactive compounds that control capillary flow. As a consequence,
in response to gravitational stress and other forms of shock that reduce effective circulation, albumin as well as ECF is
rapidly shifted from plasma and sequestered in ISF. When this has occurred, as in burn shock, restoration is better effected
by generous expansion of ECF with Ringer’s solution alone, rather than with Ringer’s solution supplemented with human serum
albumin or other colloid. Restoring both PV and ISF volume restores lymph circulation and returns sequestered albumin to PV.
Received: 12 November 1998 / Revised: 30 March 1999 / Accepted: 2 April 1999 相似文献