The Effect of Chinese Traditional Medicine of Kidney Invigoration on Bone Mass after Colles' Fracture

Colles'fracture of the distal forearm is acommon fracture in postmenopausal women.Of-ten,it is an early sign of general osteoporosis.Bone mineral density(BMD) of the lumbar spineis lower in women with a Colles'fracture than inage- matched controls.This is accompanied by ahigher risk for a vertebral deformity[1] .So thegroup of patients who present with a Colles'fracture should be to prevention of further osteo-porotic fractures.Mi Gu Pian,a kind of ChineseTraditional Medicine of kindney i…     

甲泛影酰胺和三碘三酰苯在颈脊髓造影CT(CTM)检查中的对比分析

本文报道100例腰椎穿刺注入非离子型水溶性造影剂后行颈脊髓造影CT(CTM)检查,共分4组:组1、组2为注入Amipaque后的60min或120min行颈椎CTM扫描;组3、组4为注入Omnipaque后的60min或120min行颈椎CTM扫描。经分析和统计学处理后提出:上述两种造影剂在颈椎CTM扫描中显影效果相同,但Omnipaque所产生的副作用明显少于Amipaque。     

肝阳上亢证患者的血浆环核苷酸变化

报告285例肝阳上亢证、阴虚阳亢证及肝肾阴虚证患者血浆环核苷酸测定,与健康人比较,有cAMP、cGMP升高,cAMP/cGMP比值降低的一致性趋势。三类证型之中,肝阳上亢证较明虚阳亢证变化显著。     

生脉注射液HPLC指纹图谱的建立

目的:建立生脉注射液的HPLC指纹图谱。方法:采用Waters Symmetry ShieldTMRP18(4.6 mm×250 mm,5μm)色谱柱,以乙腈-水为流动相,梯度洗脱,流速为1 mL.min-1,检测波长203 nm,柱温30℃。结果:本色谱条件下生脉注射液各成分得到了良好分离,指纹图谱由23个特征峰组成。结论:所建立的指纹图谱分离效果好,信息量大,可作为生脉注射液的指纹图谱使用,以便更好地控制该产品的质量。     

PBL联合CTM教学法在面向医学生计算机基础教学中的应用

为提高高校非计算机专业计算机基础的教学水平,加强培养非计算机专业学生应用计算机创新能力以及协作互助能力,将以问题为基础教学法(Problem based learning,PBL)和案例教学法(Case Teaching Method,CTM)联合应用于大学计算机基础教学中,实践结果表明,教学效果良好,新型教学模式得到学生认可,考试成绩有所提高,加强了学生的自主探索能力和协作共事能力。     

Establishing diagnostic cut-off criteria for the COBAS AmpliPrep/COBAS TaqMan HIV-1 Qualitative test through validation against the Amplicor DNA test v1.5 for infant diagnosis using dried blood spots

Background

As antibody testing cannot confirm HIV-1 infection in children less than 18 months of age, diagnosis in these children depends on nucleic acid testing. The COBAS^® AmpliPrep/COBAS^® TaqMan^® (CAP/CTM, Roche^® Molecular Systems, Inc., Branchburg, NJ) HIV-1 Qualitative test is a total nucleic acid real-time PCR assay utilising whole EDTA blood or dried blood spots (DBS), which recently replaced the Roche^® AMPLICOR^® DNA test v1.5 (Amplicor) as the diagnostic HIV PCR assay in many South African laboratories. For the Amplicor assay, stringent diagnostic criteria were previously formulated for the local population, and a comparison reported the CAP/CTM's sensitivity at 99.7% and specificity at 100% for both sample types compared to these Amplicor criteria.

Objectives

To validate the assay prior to introduction in our laboratory and to define stringent diagnostic cut-off criteria.

Study design

Whole EDTA blood samples from patients younger than 18 months sent for routine HIV-1 diagnosis were tested by Amplicor, and positive results were confirmed from DBS. CAP/CTM assays were subsequently performed from DBS.

Results

The CAP/CTM had a sensitivity of 98.8% and a specificity of 97.1%, but a positive predictive value (PPV) of only 78.7% compared to the Amplicor assay. Samples positive by CAP/CTM but negative by Amplicor displayed poor amplification curves compared to concordant positive samples. Upon re-testing those with sufficient material available by CAP/CTM, all showed negative results.

Conclusions

The decreased PPV may either be due to false positive CAP/CTM results, or increased sensitivity compared to the Amplicor assay. Criteria were formulated for defining presumed false-positive results.     

QQ群辅助CTM教学法在医学影像教学中的应用

针对医学影像学教学中存在的问题,提出并将QQ群引入CTM教学模式中。在介绍该模式使用方法及效果的基础上,指出CTM教学法与QQ群教学法优势互补,有助于提高学生学习兴趣,培养其分析问题和解决问题的能力。     

螺旋CTM诊断丛神经根损伤

目的应用螺旋CTM诊断丛神经根性损伤。方法椎管内注入Omnipaque 10ml,螺旋CTM扫描后图象重建。结果诊断正确率97.6%结论螺旋CTM是诊断臂丛神经损伤较为理想的影像学方法。     

肝阳上亢证患者血浆血栓素B_2和6-酮-前列腺素F_1α

肝阳上亢证患者血浆血栓素B_2、6-酮-前列腺素F_(1α)水平及其比值均升高,揭示肝阳上亢证呈血栓素A_2和前列环素平衡失调     

影响慢性压迫性颈脊髓病手术疗效的因素分析

对６６例慢性压迫性颈脊髓病患者的颈椎ＣＴＭ采用图像分析系统进行了测量研究。发现脊髓受压最重部位的脊髓横断面积（髓断面）、髓断面／椎管横断面积（管断面）比值及髓断面／椎体横断面积 （椎断面）与手术疗效密切相关。若髓断面积小于３０ｍｍ２，伴有髓断面／管断面比值＜０．２及髓断面／椎断面比值＜０．０８时，术后疗效不佳，脊髓功能有不可逆性改变的倾向。除病程、脊髓受压节段数及脊髓矢径／横径之比值等因素外，髓断面、髓断面／管断面及髓断面／推断面的比值三者是预测疗效的最可靠指标。