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121.
目的:为了检验早期康复护理对脑卒中患日常生活能力(ADL)的影响,本对比观察了早期介入康复护理和一般临床护理(以下简称对照组)两组病例。结果:发现早期介入康复护理患的肩痛、肩手综合症的发生率较一般护理组明显降低(P〈0.01),B指数康复护理组较一般护理组明显提高(P〈0.01),而肩关节脱位发生率两组之间无明显差异(P〉0.05)。结论:说明早期介入康复护理能明显提高脑卒患的日常生活能力 相似文献
122.
目的:对全喉切除术后Ⅰ期气管食管造瘘术式发音重建进行临床评价。方法:用改良Amstsu法对20例患者实施全喉切除术后Ⅰ期发音重建术。结果:20例全喉切除术后发音重建术患者随访1 ̄8年,最终有16例获得发音功能。结论:全喉切除术后一期完成气管-食管造瘘发音重建术,适用于所有的全喉切除术或同期作根治性颈廓清术及术后放疗的患者,能较好地解决全喉切除术后发音问题。 相似文献
123.
Chronic fatigue syndrome (CFS) is a controversial conditionthat many occupational physicians find difficult to advise on.In this article we review the nature and definition of CFS,the principal aetiologic hypotheses and the evidence concerningprognosis. We also outline a practical approach to patient assessment,diagnosis and management. The conclusions of this review arethen applied to the disability discrimination field. The implicationsof the new UK occupational health legislation are also examined.Despite continuing controversy about the status, aetiology andoptimum management of CFS, we argue that much can be done toimprove the outcome for patients with this condition. The mosturgent needs are for improved education and rehabilitation,especially in regard to employment. Occupational physiciansare well placed to play an important and unique role in meetingthese needs. 相似文献
124.
A case is presented of an eight-year-old child with a mediastinal tumour, who had developed acute renal failure following the institution of steroid therapy. Intrapleural analgesia was successfully used for the insertion of a peritoneal dialysis catheter so that the considerable risks of general anaesthesia were avoided. Subsequent dialysis allowed chemotherapy to commence and, as a result of the shrinkage in tumour size, general anaesthesia was administered safely two days later. The purpose of this report is to highlight the use of intrapleural analgesia in children as an alternative to general anaesthesia, when the latter is contraindicated. The mechanism of action of intra-pleural analgesia and the risks of anaesthesia in the presence of a mediastinal tumour are discussed. 相似文献
125.
Jonathan P. Purday 《Journal canadien d'anesthésie》1994,41(9):818-844
Monitoring of paediatric anaesthesia has become increasingly more complex in recent years and this is particulary true of
cardiac anaesthesia. The purpose of this review is to give a comprehensive update of published material related to both routine
and specialized cardiac monitoring. Routine monitoring can be particularly affected by the alterations of cardiac rhythm,
blood flow, cardiac output and oxygenation which result from the congenital heart abnormalities themselves, the type of surgery
undertaken and the effects of cardiopulmonary bypass. The use of specialized monitoring is becoming more widespread, particularly
in the areas of cerebral function, mixed venous oxygenation, cardiac output measurement and coagulation. In the last five
years, with the development of smaller probes, a great deal has been published on transoesophageal echocardiography. The use
of the current monitors of cerebral function still remains controversial despite the need for a monitor of adequate brain
perfusion, reflecting the need for a great deal of further research in this area. This review will concentrate on particular
areas which have seen the most profound changes and on monitoring that may form the standards of tomorrow. Finally, amongst
all the technology, it should not be forgotten that the most important clinical monitor is the bedside clinical monitoring
of the physicians themselves.
Depuis quelques années, le monitorage de l’anesthésie pédiatrique devient déplus en plus complexe et tout particulièrement
en anesthésie cardiaque. L’objectif de ce travail consiste à passer en revue la littérature actuelle qui traite du monitorage
usuel et spécialisé. Le monitorage usuel peut être influencé par les modifications de la fréquence cardiaque, du courant sanguin,
du débit cardiaque et de l’oxygénation provoqués par les anomalies cardiaques congénitales, du type de chirurgie et des retentissements
de la circulation extracorporelle. L’utilisation du monitorage spécialisé est de plus en plus répandu et concerne particulièrement
la circulation cérébrale, l’oxygénation du sang veineux mêlé, la mesure du débit cardiaque et la coagulation. Au cours des
cinq dernières années, le développement de sondes plus petites a généré de nombreuses publications sur l’échocardiographie
transoesophagienne. L’utilisation des moniteurs actuels de la fonction cérébrale demeure sujet à controverse bien qu ’un moniteur
de perfusion cérébrale adéquat demeure toujours aussi essentiel, confirmant ainsi le besoin de recherches supplémentaires
sur ce sujet. Ce survol se portera spécialement sur les champs d’activités qui ont connu les changements les plus profonds
et sur le monitorage qui établira les standards du futur. Finalement, au milieu de cette technologie, il ne faut jamais oublier
que le moniteur clinique le plus important se trouve au chevet du malade en la personne du médecin. 相似文献
126.
The treatment of cerebral arteriovenous malformations (AVM) or vascular anomalies are challenging neurosurgical procedures for an anaesthetist. Large AVMs are uncommon in children. Only 18% of AVMs become symptomatic before the age of 15 yr. This series reviews the experience at this institution during the period of 1982 to 1992. The symptoms at the time of presentation are varied and include haemorrhage (50%), seizures and hydrocephalus (36%) or congestive cardiac failure (18%). Symptoms of congestive heart failure predominate in the new-born whilst neurological symptoms, such as stroke, seizures or hydrocephalus occur more commonly in infants and older children. Approximately one third of AVMs in childhood present acutely. Radiological investigations, e.g., CT scan, MRI and cerebral angiography are essential to identify the precise location of the lesion. Therapeutic intervention in the acute presentation may involve craniotomy for evacuation of haematoma and treatment of increased intracranial pressure (ICP). Control of seizures and congestive heart failure may take priority and allow time to plan the elective procedures of embolization and surgical excision of the AVM. Operative intervention is hazardous and peroperative complications can be expected in more than 50% of patients. The morbidity and mortality associated with cerebral AVM are high, especially in infants who present in the neonatal period with congestive cardiac failure. The overall mortality in this series was 20%. Children presenting with intracranial arteriovenous malformations require a multidisciplinary approach. The successful management of anaesthesia either for embolization or surgical resection necessitates an understanding of the disciplines of paediatric and neuroanaesthesia. Special care and specific attention to detail may contribute to reduce the high morbidity and mortality encountered in these compromised children. 相似文献
127.
Alan Kreidstein Martin R. Boorin Paul Crespi Philip Lebowitz Samuel Barst 《Journal canadien d'anesthésie》1994,41(5):423-426
Hunter syndrome is one of a heterogeneous group of recessively inherited mucopolysaccharide storage diseases (MPS) with similar
biochemical defects manifested by impairments in muco-polysaccharide catabolism with variable but progressive clinical courses.
Abnormal accumulation and deposition of mucopoly-saccharides in the tissues of several organs lead to numerous anatomical,
musculoskeletal and neurological abnormalities which are known to complicate anaesthetic and airway management. Hunter syndrome
has a wide variance of clinical phenotypes ranging from mild to severe. We present a patient having physical and neurological
features consistent with a severe clinical presentation of Hunter syndrome (MPS, Type II). Following a seemingly uneventful
intraoperative anaesthetic course including isoflurane, nitrous oxide and fentanyl (0.93 μg · kg−1), resumption of spontaneous ventilation and return to consciousness were delayed until intravenous naloxone (200 μg) was
administered 100 min after the opioid administration. The cause of delayed recovery from anaesthesia in this patient is unknown.
La maladie de Hunter fait partie du groupe des affections hétérogènes héréditaires et récessives des mucopolysaccharidoses
(MPS) avec lesquelles elle partage les mêmes anomalies biochimiques. Celles-ci se manifestent par des altérations du catabolisme
des mucopolysaccharides et une évolution variable et progressive. L’accumulation anormale de mucopolysaccharides dans les
tissus de plusieurs organes provoque de nombreuses lésions musculo-squelettiques et neurologiques qui compliquent la gestion
de l’anesthésie et des voies aériennes. Les phénotypes cliniques de la maladie de Hunter varient de légers à graves. Cette
observation porte sur un patient qui présente des manifestations cliniques graves de la maladie de Hunter (MPS type II). A
la suite d’une anesthésie sans problèmes réalisée avec de l’isoflurane, du protoxyde d’azote, et du fentanyl (0,93 μg · kg−1), le retour normal à la ventilation spontanée et à la conscience est retardé jusqu’à l’administration de naloxone (200 mg)
iv effectuée 110 min après le morphinique. La raison de ce retard est inconnue. 相似文献
128.
Richard F. Kaplan Michael Garcia Raafat S. Hannallah 《Journal canadien d'anesthésie》1995,42(1):16-20
The neuromuscular blocking effects of mivacurium during sevoflurane or halothane anaesthesia was studied in 38 paediatric
patients aged 1–12 yr. All received premedication with midazolam, 0.5 mg · kg−1 po and an inhalational induction with up to 3 MAC of either agent in 70% N2O and O2. The ulnar nerve was stimulated at the wrist by a train-of-four stimulus every ten seconds and the force of adduction of
the thumb recorded with a Myotrace force transducer. Anaesthesia was maintained with a one MAC end-tidal equivalent of either
volatile agent for five minutes before patients received mivacurium (0.2 mg · kg−1) iv. The onset of maximal blockade occurred in 2.4 ± 1.26 (mean ± SD) min with halothane and 1.8 ± 0.54 min with sevoflurane
(NS). Four patients failed to achieve 100% block (3 halothane, 1 sevoflurane). The times from injection to 5, 75, and 95%
recovery during sevoflurane (9.8 ± 2.6, 19.5 ± 4.4, and 24.2 ± 4.8 min) were greater than during halothane anaesthesia (7.2
± 2.2, 15.0 ± 4.0, 19.2 ± 4.9 min, respectively (P < 0.005). All patients demonstrated complete spontaneous recovery of neuromuscular
function (T1 > 95%, T4/T1 > 75%) during the surgery which lasted 24–63 min. All patients showed clinical signs of full recovery of neuromuscular blockade
(i.e., headlift, gag, or cough). Pharmacological reversal was not required. It is concluded that following a single intubating
dose of mivacurium, the time to maximum relaxation was not different during halothane and sevoflurane anaesthesia; recovery
times to 5, 75 and 95% twitch height were longer during sevoflurane anaesthesia and neuromuscular reversal was not necessary.
L’activité neurobloquante du mivacurium pendant l’anesthésie au sévoflurane ou à l’halothane fait l’objet de cette étude réalisée
chez 38 enfants de 1 à 12 ans. Tous ont été prémédiqués au midazolam 0,5 mg · kg−1 et l’anesthésie est induite avec un agent volatil jusqu’à MAC 3 de l’un des agents dans du N2O à 70%. Le nerf cubital était stimulé au poignet au train de quatre aux dix seconds et la force de l’adduction du pouce mesurée
avec un transducteur de force Myotrace. L’anesthésie était entretenue avec l’équivalent MAC I d’un des deux agents volatils
pendant cinq minutes avant l’administration de mivacurium (0,2 mg · kg−1). Le début du bloc maximum est survenu dans 2,4 ± 1,26 (moyenne ± SD) min avec l’halothane et 1,8 ± 0,54 min avec le sévoflurane
(NS). Quatre patients n’ont pas été bloqués à 100% (trois avec l’halothane, un avec le sévoflurane). L’intervalle séparant
l’injection à 5; 75, et 95% de la récupération pendant l’anesthésie au sévoflurane (9,8 ± 2,6, 19,5 ± 4,4 et 24,2 ± 4,8 min)
a été plus long que pendant l’anesthésie à l’halothane (7,2 ± 2,2, 15,0 ± 4,0, 19,2 ± 4,9 min, respectivement (P < 0,005).
An moniteur, chez tous les patients, la fonction neuromusculaire a récupéré spontanément (T1 > 95%, T4/T1 > 75%) au cours de la chirurgie qui a duré de 24–63 min. Tous les patients montraient aussi les signes cliniques d’une récupération
complète (par ex., levée de la tête, réflexe pharyngé ou toux). Aucun antagoniste pharmacologique n’a été requis. Il est conclu
que le délai jusqu’à la relaxation maximum après une seule dose d’intubation de mivacurium ne diffère pas entre l’anesthésie
à l’halothane et l’anesthésie au sévoflurane; les délais de retour à 5, 75 et 95% de la hauteur du twitch sont plus longs
pendant l’anesthésie au sévoflurane et il n’est pas nécessaire d’antagoniser le bloc neuromusculaire.
Supported in part by a grant from Abbott Laboratories, Chicago, Illinois. 相似文献
Supported in part by a grant from Abbott Laboratories, Chicago, Illinois. 相似文献
129.
William M. Splinter Michael R. N. Baxter H. Marion Gould Leslie E. Hall Helen B. MacNeill David J. Roberts Lydia Komocar 《Journal canadien d'anesthésie》1995,42(4):277-280
Vomiting is a common, unpleasant aftermath of tonsillectomy in children. Intraoperative intravenous ondansetron (OND) reduces vomiting after this operation. Our doubleblind, placebocontrolled, randomized investigation studied the effect of the oral form of OND on vomiting after outpatient tonsillectomy in children. We studied 233 healthy children age 2–14 yr undergoing elective tonsillectomy. Subjects were given placebo (PLAC) or OND 0.1 mg · kg?1 rounded off to the nearest 2 mg one hr before surgery. Anaesthesia was induced with either propofol or halothane/N2O. Vecuronium 0.1 mg · kg?1 was administered at the discretion of the anaesthetist. Anaesthesia was maintained with halothane/N2O, 50 μg · kg?1 midazolam iv and 1–1.5 mg · kg?1 codeine im. At the end of surgery, residual neuromuscular blockade was reversed with neostigmine and atropine. All episodes of inhospital emesis were recorded by nursing staff. Rescue antiemetics in the hospital were 1 mg · kg?1 dimenhydrinate ivfor vomiting × 2 and 50 μg · kg?1 droperidol iv for vomiting × 4. Parents kept a diary of emesis after discharge. Postoperative pain was treated with morphine, codeine and/or acetaminophen. The two groups were similar with respect to demographic data, induction technique and anaesthesia time. Oral OND (n = 109) reduced postoperative emesis from 54% to 39%, P < 0.05. This effect was most dramatic inhospital, where 10% of the OND-patients and 30% of the PLAC-group vomited, P < 0.05. The OND-subjects required fewer rescue antiemetics, 7% vs 17%, P < 0.05. In conclusion, oral ondansetron decreased the incidence of vomiting after outpatient tonsillectomy in children. 相似文献
130.
We report the anaesthetic management of an eight-year-old asthmatic boy with Bartter’s syndrome who had bilateral orchidopexy with caudal epidural analgesia. Bartter’s syndrome is a rare congenital disorder characterized by hypokalaemic hypochloraemic metabolic alkalosis, hyperaldosteronism, hyperreninaemia and hyperplasia of the juxtaglomerular apparatus of the kidneys. Characteristically, although these patients are normotensive they may be hypovolaemic. They may have unstable baroreceptor responses and show marked resistance to vasopressors. Hence, fluid, acid-base and electrolyte imbalances along with haemodynamic instability pose particular problems in their anaesthetic management. Previous case reports have described the management of these patients with general anaesthesia, our patient had his orchidopexy with caudal epidural analgesia using plain bupivacaine 0.5%. The patient was haemodynamically stable throughout surgery and was comfortable with caudal analgesia as the sole anaesthetic. Hypovalaemia, acid-base status and electrolyte imbalance were treated before instituting caudal epidural analgesia. We present this case report which describes the anaesthetic considerations in the light of the pathophysiology of Bartter’s syndrome. 相似文献