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41.
目的:探讨腮腺深叶癌切除面神经后,即刻功能性修复的临床效果。方法:对1984年1月至2005年10月间收治的11例腮腺癌患者,术中采用将肿瘤连同腮腺及面神经切除,同时行颈丛神经移植重建面神经的治疗方法。结果:术后面神经功能均完全恢复,所有患者术后6个月复诊,见患者静态时面部对称,动态时口角轻度偏斜,术后一年两侧面部完全对称,睁、闭眼及提口角功能基本恢复正常。结论:腮腺癌根治术中采用颈丛神经移植能有效地恢复面神经的功能,既达到肿瘤切除的彻底性,又符合功能外科的发展要求,是一种比较理想的手术方法。 相似文献
42.
颈性眩晕的分型治疗及疗效分析 总被引:7,自引:0,他引:7
目的 将颈性眩晕分为上、下颈性眩晕,采取不同治疗方法并与常规治疗方法的疗效比较,以寻求更好的治疗方法。方法 将135例颈性眩晕随机分为试验组和对照组,对其治愈率及治疗时间进行统计学分析。结果 试验组的治愈率高于对照组,而试验组的治疗时间短于对照组,均有统计学意义。结论 对颈性眩晕进行分型并采用不同的治疗方法能提高治愈率,缩短治疗时间。 相似文献
43.
Abstract: The use of neuromuscular electrical stimulation (NMES) for rehabilitation of gait in spinal patients is widely known. The best results can be obtained with the use of biomechanical sensors and a closed loop NMES system. One of the biggest problems faced in the design of control systems for closed-loop operation, in gait rehabilitation, is the variation of the mechanical conditions during the phases of gait. This work presents a new approach to ease the design of rule-based closed loop systems for operation in conditions such as gait rehabilitation. 相似文献
44.
In the present study, we examined the effect of intracerebroventricularly (i.c.v.) injected choline on both basal and stimulated oxytocin release in conscious rats. I.c.v. injection of choline (50–150 μg) caused time- and dose-dependent increases in plasma oxytocin levels under normal conditions. The increase in plasma oxytocin levels in response to i.c.v. choline (150 μg) was greatly attenuated by the pretreatment of rats with atropine (10 μg; i.c.v.), muscarinic receptor antagonist. Mecamylamine (50 μg; i.c.v.), a nicotinic receptor antagonist, failed to suppress the effect of 150 μg choline on oxytocin levels. Pretreatment of rats with 20 μg of hemicholinium-3 (HC-3), a specific inhibitor of choline uptake into nerve terminals, greatly attenuated the increase in plasma oxytocin levels in response to i.c.v. choline injection. Osmotic stimuli induced by either oral administration of 1 ml hypertonic saline (3 M) following 24-h dehydration of rats (type 1) or an i.c.v. injection of hypertonic saline (1 M) (type 2) increased plasma oxytocin levels significantly, but hemorrhage did not alter basal oxytocin concentrations. The i.c.v. injection of choline (50, 150 μg) under these conditions caused an additional and significant increase in plasma oxytocin concentrations beyond that produced by choline in normal conditions. These data show that choline can increase plasma oxytocin concentrations through the stimulation of central cholinergic muscarinic receptors by presynaptic mechanisms and enhance the stimulated oxytocin release. 相似文献
45.
磁刺激运动诱发电位在腰椎间盘突出所致的腰骶神经根病变中的应用研究 总被引:2,自引:0,他引:2
在35例有L5和/或S1神经根损害表现的腰椎间盘突出患者腰椎区进行磁刺激运动诱发电位(MEP)检查,测定、记录胫前肌、展肌和小趾展肌MEP的起始潜伏期(OL)。结果显示,35例中至少有一条总侧肌肉MEP异常33例(94.3%)。在L4-5椎间盘突出中,以胫前肌的MEP异常为主;在L5-S1椎间盘突出中,以小趾展肌的MEP异常为主。表明腰椎区MEP检查对腰椎间盘突出所致的腰骶神经根病变较为敏感,可为临床诊断提供可靠依据并有助于定位诊断。 相似文献
46.
J. H. Meier Dr. W. L. C. Rutten H. B. K. Boom 《Medical & biological engineering & computing》1995,33(3):409-417
Experimentally, during electrical nerve stimulation, the influence is examined of two intrafascicular anodes on the force
recruitment with one intrafascicular cathode. It is found that the anodes suppress recruitment and that this effect is more
pronounced when the distance of the anodes to the cathode is decreased, or when the anodal currents are increased. The measured
recruitment curve patterns can be qualitatively explained by a nerve stimulation model that calculates theoretical recruitment
curves for intrafascicular multi-electrode configurations. Discrepancies between the experimental and the theoretical recruitment
curves are seen, but these can be understood by taking into account a non-uniform fibre distribution. 相似文献
47.
本工作观察了乙酰胆硷(Ach)和电刺激迷走神经对0.6N HCl引起的胃粘膜出血性损伤的保护作用,发现皮下注射50μg/kg的氯化Ach和电刺激膈下迷走神经5min,可明显降低HCl引起的胃粘膜出血量,这一作用可被消炎痛及阿托品所阻断。提示这种保护作用是通过依赖于M-受体的内源性前列腺素。 相似文献
48.
E. M. Robertson R. C. Miall 《Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale》1997,117(1):148-152
The human arm is kinematically redundant, which may allow flexibility in the execution of reaching movements. We have compared
reaching movements with and without kinematic redundancy to unpredictable double-step targets. Subjects sat in front of a
digitising tablet and were able to view an arc of four targets reflected in the mirror as virtual images in the plane of the
tablet. They were instructed to move, from a central starting point, in as straight a line as possible to a target. In one-third
of trials, the target light switched to one of its neighbours during the movement. Subjects made 60 movements using shoulder,
elbow and wrist and then another 60 movements in which only shoulder and elbow movement were allowed. By restraining the wrist,
the limb was made non-redundant. The path length was calculated for each movement. In single-step trials, there was no significant
difference between path lengths performed with and without wrist restraint. As expected there was a significant increase in
path length during double-step trials. Moreover this increase was significantly greater when the wrist was restrained. The
variability across both single- and double-step movements was significantly less while the wrist was restrained. Importantly
the performance time of the movements did not alter significantly for single-step, double-step or restrained movements. These
results suggest that the nervous system exploits the intrinsic redundancy of the limb when controlling voluntary movements
and is therefore more effective at reprogramming movements to double-step targets.
Received: 24 March 1997 / Accepted: 7 July 1997 相似文献
49.
Walter G. Sannita Luisa Lopez Lino Maggi Guido Rosadini 《Documenta ophthalmologica. Advances in ophthalmology》1988,70(1):89-96
L-acetylcarnitine is a compound with cholinergic properties and putative action on the visual system and the glucose metabolism. Ten healthy, emmertropic volunteers (age range: 21 to 28 years) were studied. Each subject was administered 5, 10, and 30 mg/kg acute intravenous doses of L-acetylcarnitine and matching placebo. Retinal oscillatory potentials to full-field flash stimulation were recorded before and 30, 60, and 120 min after administration. A systematic reduction of the implicit time of the P2 and N2 oscillatory potential components was observed after administration of the 10 and 30 mg/kg doses: significant changes were not evident at the 5 mg dose or after placebo. The latency reduction was significantly correlated with the postdrug increment of the L-acetylcarnitine plasma concentration. No other systematic modification in latency of amplitude was observed.The results were presented in part at the XXV I.S.C.E.V. Symposium, Sarasota (Florida), April 26–30, 1987. 相似文献
50.
Persistent developmental stuttering (PDS) shares clinical features with task-specific dystonias. In these dystonias, intracortical inhibition is abnormally weak. We therefore sought to determine intracortical inhibition and intracortical facilitation in PDS. In 18 subjects with PDS since childhood (mean age, 39.4 [SD 13.0] years) and 18 speech-fluent controls (43.6 [14.3] years), we investigated resting and active motor thresholds as well as intracortical inhibition and facilitation of the optimal representation of the abductor digiti minimi of the dominant hand using transcranial magnetic stimulation. In PDS, the resting and active motor thresholds were increased, whereas intracortical inhibition and facilitation were normal. Normal intracortical excitability makes a pathophysiological analogy between focal dystonia and PDS less likely. The enhanced motor threshold suggests reduced motor cortical neuronal membrane excitability in PDS. 相似文献