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31.
目的通过检测子宫内膜异位症(EMs)患者血清及腹腔液中血小板衍生生长因子(PDGF)、血管细胞粘附分子-(VCAM-1)浓度,探讨PDGF和VCAM-1在EMs发病中的作用。方法选取手术后病理证实为EMs的40例患者为EMs组,其中I~II期17例,III~IV23例;非EMs组20例作为对照组。应用酶联免疫吸附法(ELISA)检测血清及腹腔液中PDGF和VCAM-1水平。结果EMs组血清及腹腔液中PDGF、VCAM-1水平均明显高于对照组(P<0.01)。随EMs期别的增加,其血清和腹腔液中PDGF、VCAM-1含量呈上升趋势;EMsIII~IV期水平显著高于I~II期(P<0.05)。EMs患者PDGF与VCAM-1呈正相关性(P<0.05)。结论EMs患者PDGF、VCAM-1表达水平升高,在EMs的发生发展中具有重要作用。 相似文献
32.
腰大池持续外引流的临床观察与护理 总被引:3,自引:0,他引:3
笔者报道72例腰大池持续外引流病人的观察与护理。认为对于腰穿持续外引流的病人,观察脑脊液的性质、量,严密观察病情变化,加强引流管的护理及基础护理,增强营养,是提高治愈率,减少并发症的重要措施。 相似文献
33.
AMAL KANBOUR-SHAKIR DAVID T. ARMSTRONG ANNE ROULEAU HEINZ W. KUNZ THOMAS J. GILL 《American journal of reproductive immunology (New York, N.Y. : 1989)》1995,33(5):367-372
PROBLEM : To determine whether seminal fluid influences the expression of MHC class I antigens on the surface of basal trophoblast cells in the placenta of the rat. METHODS : Transfer of DA × DA embryos into a WF (allogeneic) or DA (syngeneic) recipient made pseudopregnant by hormonal treatment followed by mating with a vasectomized male (seminal fluid) or by mechanical stimulation (no seminal fluid). Antigen expression was determined by electron microscopic immunocytochemistry using the appropriate gold-labeled monoclonal antibodies. RESULTS : Seminal fluid did not affect the expression of MHC class I antigens on the surface of the basal trophoblast in either allogeneic or syngeneic matings. CONCLUSIONS : The suppression of the expression of paternal class I antigens on the surface of the basal trophoblast cells in allogeneic pregnancies most likely occurs at the genome level shortly after fertilization. 相似文献
34.
头低位模拟失重状态对前庭功能的影响 总被引:4,自引:1,他引:3
为研究头低位模拟失重对运动病症状、垂直视动眼震(VOKN)及体液重新分配的影响,在头低位-10°的模拟失重状态下,采用大视野的垂直视动刺激,观察18名正常人的运动病症状、VOKN、激素(AVP、VIP、CORT、ALDO)的反应特点。结果表明,头低位-10°状态下的大视野垂直视动刺激可以诱发出明显的运动病症状,头低位-10°的垂直视动刺激比坐位更容易诱发运动病。坐位状态VOKN慢相速度有明显的方向性不对称,敏感组VOKN方向性不对称有显著差异(P<0.05)。头低位-10°时VOKN的不对称现象不明显,向下方向运动的VOKN慢相速度显著增加。分析指出,头低位-10°状态下垂直视动刺激比坐位和秋千刺激的贡献率大。尿中CORT(皮质醇)在秋千和头低位的垂直视动刺激前后有显著性增加。提示:大视野的垂直视动刺激与头低位-10°两种刺激的结合可能成为预测空间运动病的方法之一. 相似文献
35.
36.
S. Jepsen A. Rühling K. Jepsen B. Ohlenbusch H.K. Albers 《Clinical oral implants research》1996,7(2):133-142
The aim of this prospective study was to characterize an implant patient population exhibiting clinical signs of peri‐implantitis and to determine subsequently the incidence of progressive attachment loss. The predictive values of diagnostic parameters were evaluated. 25 patients with 54 endosseous implants that had been loaded for 41±15 months were included in the study. Clinical parameters included the assessment of plaque, bleeding on probing, probing depth, attachment levels, and Periotest® values. Probing measurements were performed in duplicate by means of a controlled force electronic probe (Periprobem). Peri‐implant crevicular fluid samples were collected and assayed for neutral proteolytic enzyme (NPE) activity (Periocheck®). Analysis of duplicate baseline probing data revealed a high degree of reproducibility (mean difference: 0.1±0.3mm). A minimum threshold of 1.0mm (>3×S.D.) loss of probing attachment was chosen to classify a site as positive for breakdown. Alternatively, the tolerance method was employed to identify sites with progressive attachment loss. After 6 months, irrespective of the analytical method, 6 percent of all sites (in 19% of the implants) and 28% of the patients had experienced further per attachment loss. There were significant differences ( p <0.05) in mean plaque (73% vs. 45%) and NPE (36% vs. 12%) scores between patients with progressive peri‐implantitis and those with stable peri‐implant conditions. Both bleeding on probing and the NPE‐test were characterized by high negative predictive values, and thus negative scores can serve as indicators for stable peri‐implant conditions. For monitoring peri‐implant health during recall visits, attachment level recordings with a controlled force electronic probe in conjunction with enzymatic diagnostic tests of the host response can be recommended. 相似文献
37.
Granulocytic sarcoma (GS) is a localized tumour of immature granulocytes that is usually associated with myelogenous leukaemia. We report an unusual case of mastoid GS with meningeal extension but no bone marrow involvement on presentation. Histological examination of the surgical specimen and the characteristic cerebrospinal fluid (CSF) cytology showing cytoplasmic granulations and Auer bodies led to the diagnosis of GS. Positive cytochemical staining of the immature CSF cells for naphtol-ASD chloroacetate esterase and myeloperoxidase confirmed their myeloid origin. Immunophenotyping did not reveal common acute lymphoblastic leukaemia antigen, cytokeratin, T or B-cell antigens. The patient underwent surgical resection of the localized tumour, followed by radiation therapy, intrathecal and systemic chemotherapy, as if he had acute myelogenous leukaemia (AML). He did not develop AML in the 21 months after the tumour resection. This case emphasizes the value of CSF cytological examination of tumour cells and the use of an immumocytochemical marker for differentiating GS from malignant lymphoma. 相似文献
38.
聚合酶链反应(PCR)对单纯疱疹病毒性脑炎的临床诊断价值 总被引:2,自引:1,他引:1
应用聚合酶链反应(PCR)检测技术对118例颅内感染性疾病患者及37例无神神经系统疾病患者脑脊液(CSF)中的单纯疱疹病毒DNA(HSV-DNA)进行了检测及分型。结果提示:“散发性脑炎”组的阳性率为38.46%(20/52),细菌、真菌性脑膜炎、其它病毒性脑炎组以及无神经系统疾病组均为阴性。作者认为:①本检测是目前单纯疹病毒性脑炎(HSE)较为简便而准确的早期诊断方法之一;②HSV分型检测,对病原诊断更具有全面性;③两型单纯疱疹病毒均可引起HSE。 相似文献
39.
用改良的ELISA检测25例正常对照组和32例急性脑血管病患者的血清和脑脊液(CSF)中的脑型肌酸激酶同功酶BB(creatine kinase isoenzyme BB)浓度。32例急性脑血管病患者CSF CKBB平均水平为16.62±8.3ng/ml,明显高于对照组(7.5—4.8ng/ml)。发病24h内CSFCKBB轻微增高,24~48h达高峰,以后下降,7天左右尚未恢复正常。病初CSF CKBB水平明显高于恢复期。9例高血压性脑出血的血肿出血量(按CT片上血肿大小计算)与患者CSF CKBB有密切关系(r=0.8127,P<0.01)。血肿体积(X)与CSF CKBB浓度(y)的回归方程y—7.945±0.872X。 相似文献
40.
B. Pfausler G. Grubwieser S. Bsch H. Vollert M. Herald E. Schmutzhard 《European journal of neurology》1995,2(6):570-572
A 37 year old male was admitted with the diagnosis of bacterial meningitis. Pneumococci were seen in the Gram stain of the cerebrospinal fluid. The clinical condition did not suggest severely raised intracranial pressure, there were no localizing signs and symptoms. CSF was turpid, with 20.100/3/mm3, mainly polymorphonuclear cells. Tumor necrosis factor alpha in CSp was greatly increased with 813 pg/ml. Parallel to the application of intravenous Penicillin G a CSF filtration was carried out. Within 214 h 225 ml CSF were filtrated through a Pall-filter, using a bidirectional pump. Cell count dropped to 720/3 cells/mm3, TNF-alpha to 39 pg/ml. The clinical course was uneventful, on day 12 the patient could be discharged without sequelae. CSF filtration may be a highly effective method to reduce from the CSF pathogenetically important cytokines, such as TNF-alpha, being responsible for intrathecal/meningeal inflammatory processes and triggered by cell-wall components of bacteria, e.g. pneumococci. 相似文献