病案环节中质量监控是提高内涵质量关键

目的探索病案质量管理的有效方法,提高病案记录的内涵质量。方法通过分析目前医院常用病案质量管理、分析、考评、反馈方法和现状。结果1．寻找目前医院病案质量管理难点。2。加强病历形成环节中的质量监控;3．加强审阅运行病历专家作用医疗需求。结论1．进一步深化和完善检查制度。2．加强医务人员对病案法制化管理的责任意识．3．网络化病案质量管理,促进病案质量的提高,有效地促进了病案质量的提高。     

医疗环节质量管理策略浅析

医疗环节质量管理是医院管理的核心,也是医院新一轮竞争力的核心,更是医院发展的永恒主题。因此,必须加强对医疗环节质量的管理。提出强化质量管理意识、建立质量控制体系、健全质量规范标准、持续改进质量管理等一系列策略。     

有效的体适能干预增强网球运动爱好者弱链接能力的研究分析

目的通过发现网球运动爱好者在网球运动中不同动力链的弱链接,进行有效的体适能干预,不仅对其弱链接的能力有所提高,还提升了运动爱好者的整体运动能力,有效地防治运动损伤。方法收集我院运动促进中心网球运动爱好者52例,日常生活中均参与相同频率和强度的网球运动,常规组在1个月周期内完成正常的运动量,体适能干预对照组在1个月周期内除了完成正常的运动量,在运动促进中心给予弱链接的专项强化即体适能干预。在运动周期前中后测评机能情况,采用体适能测试单项评分标准及等速肌力测试仪评估肌肉能力、关节活动度,进行对比研究分析。结果有效体是能干预组网球爱好者弱链接环节的肋力、关节活动度均16常规组提高,差异有统计学意义（P〈0.05）。结论通过对网球运动爱好者实施有效的体适能干预,不仅强化了弱链接的能力,还提升了运动爱好者的整体运动能力,争取通过改善运动弱链接的能力为不同年龄阶段的各种项目运动爱好者制定体适能干预计划时提供一个参考,值得推广。     

医院住院收费环节监控系统的创建

目的：研究创建医院收费环节监控系统,能及时发现和解决住院病人费用信息不准确的问题,提高财务管理部门的工作管理水平。方法：系统针对不同人员采用不同功能视图,从问题产生及解决的流程入手,设计医院收费环节监控系统。结果：创建收费环节监控系统后,准确对医嘱和费用进行了关联,提高了工作效益。结论：创建收费环节监控系统各类人员均可查看到病人的费用情况,提高双方工作效益,有利于医技科室工作人员、医护人员与收费人员的沟通,加快费用审核的速度,提高费用的完整性。     

The NMDA receptor subunit NR2B of neonatal rat brain: complex formation and enrichment in axonal growth cones

The N-methyl-d -aspartate (NMDA) subtype of ionotropic glutamate receptors comprises a family of highly homologous subunits which assemble into oligomeric protein complexes. Alterations in subunit composition are developmentally regulated, leading to functionally distinct receptor populations. Here, the contribution of the subunit NR2B to NMDA receptor complex formation was analysed in neonatal rat brain, employing polyclonal antibodies raised against NR2B-specific synthetic peptides. By hydrodynamic size fractionation of the solubilized receptor protein and chemical cross-linking, NR2B antigen was found to be associated with several protein species of up to 690 kDa molecular weight. These observations show NR2B to be part of a multimeric receptor complex. Fractionation of cortex homogenates from E18 rat embryos on sucrose density gradients revealed NR2B polypeptide to be highly enriched in axonal growth cones. A similar distribution was found by fluorescence microscopy of immature hippocampal neurons, showing a preferential accumulation of NR2B antigen in axonal growth cones and varicosities. In mature cells, NR2B antigen displayed a punctated distribution pattern with redistribution to somato-dendritic spheres. The association of NR2B with axonal growth cones and processes of immature neurons suggests a role of NMDA receptors in the regulation of neurite outgrowth and migration.     

Schwartz-Jampel syndrome associated with von Willebrand's disease

Summary We report a very rare case of Schwartz-Jampel syndrome associated with von Willibrand's disease. This association might be coincidental because of the different modes of inheritance of the two disorders. However, we speculate that there might be some link between the two disorders, for example in the locus of the affected gene.     

校企合作教育新模式的实践探索——基于应用型本科人才培养

阐述了应用型本科院校开展校企合作教育的一种新模式——"订单式培养环节"的概念与内涵,介绍了这种模式在应用型本科专业的实施过程及效果,总结了该模式实践探索的经验,并对其运行机制、质量保障机制等方面进行了探讨。     

药品市场流通系统结构及流通成本研究

目的:研究药品市场流通系统结构和药品流通成本。方法:研究药品流通宏观结构和微观结构的组成规律,引入流通环节(y)、流通幅度(n)、末端节点(m)及交易关系的数量概念,用数学模型研究它们相互之间的关系,并用交易关系在各环节所占的比例分析药品流通成本。结果:药品流通在宏观结构和微观结构组成上有其确定的规律。在微观结构上,药品流通呈树状流通结构,末端节点(m)及流通幅度(n)决定流通环节(y),三者之间的关系为:y=lnm/lnn。交易关系在末端环节所占的比例远远高于中间环节。结论:按模型计算,交易关系主要集中在末端环节,压缩中间环节数量并不能有效地减少交易关系的数量,对压缩流通成本也不会产生作用。     

Composition of perineuronal nets in the adult rat cerebellum and the cellular origin of their components

The decrease in plasticity that occurs in the central nervous system during postnatal development is accompanied by the appearance of perineuronal nets (PNNs) around the cell body and dendrites of many classes of neuron. These structures are composed of extracellular matrix molecules, such as chondroitin sulfate proteoglycans (CSPGs), hyaluronan (HA), tenascin-R, and link proteins. To elucidate the role played by neurons and glial cells in constructing PNNs, we studied the expression of PNN components in the adult rat cerebellum by immunohistochemistry and in situ hybridization. In the deep cerebellar nuclei, only large excitatory neurons were surrounded by nets, which contained the CSPGs aggrecan, neurocan, brevican, versican, and phosphacan, along with tenascin-R and HA. Whereas both net-bearing neurons and glial cells were the sources of CSPGs and tenascin-R, only the neurons expressed the mRNA for HA synthases (HASs), cartilage link protein, and link protein Bral2. In the cerebellar cortex, Golgi neurons possessed PNNs and also synthesized HASs, cartilage link protein, and Bral2 mRNAs. To see whether HA might link PNNs to the neuronal cell surface by binding to a receptor, we investigated the expression of the HA receptors CD44, RHAMM, and LYVE-1. No immunolabelling for HA receptors on the membrane of net-bearing neurons was found. We therefore propose that HASs, which can retain HA on the cell surface, may act as a link between PNNs and neurons. Thus, HAS and link proteins might be key molecules for PNN formation and stability.