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11.
David Friedman Lois Putnam Walter Ritter Marla Hamberger Steven Herman 《Psychophysiology》1992,29(5):593-609
Event-related potentials were recorded in a developmental study of picture matching using an adaptation of Posner's (1978) letter-matching tasks. Subjects ranging in age from 6-39 were asked to decide whether two line drawings, presented sequentially, were the same or different on the basis of physical (physical identity), nominal (name identity), or categorical (category identity) criteria. The amplitude of a negativity at 400 ms (Neg400) increased as the number of dimensions on which the two line drawings differed increased. This effect held for all age groups, and was interpreted as reflecting the degree of semantic and/or physical relationship between the two pictures. However, one finding for Neg400 did suggest a qualitative difference in processing mode between the younger and older subjects. Both Neg400 and P3b latencies showed highly significant linear age trends, decreasing with increasing age. These age-related changes were interpreted as demonstrating quantitative speed of processing differences among age groups. The latencies of both Neg400 and P3b increased as the matching criteria became more complex. Moreover, P3b latency increased as the number of dimensions on which the two pictures differed increased, and this did not interact with age. Although both Neg400 and P3b showed age-related changes in scalp distribution, the fact that each was related to the experimental variables in similar fashion in all age groups suggested that they were homologous components across the age range studied. Taken as a whole, the data support continuity of information processing during these tasks across a wide age range. 相似文献
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Margaret O''Dougherty Gary G. Berntson Sarah T. Boysen Francis S. Wright Douglas Teske 《Psychophysiology》1988,25(3):305-315
Cardiac responses to non-signal stimuli and to signal stimuli in a vigilance task were examined in children born with congenital heart defects (CHD), and in normal and attention deficit disordered (ADD) subjects. Overall task performance was lower in subjects with heart defects and in the ADD group. Cardiac measures revealed that normal children displayed significantly larger heart rate deceleration to the target stimuli than did either of the clinical groups. Moreover, although no group differences were observed in the cardiac response to non-signal auditory stimuli, exaggerated heart rate deceleration was observed to vibrotactile stimuli in both the clinical groups. Regression analyses revealed that the magnitude of the cardiac response to somatosensory stimuli was predictive of task performance (both within and between subject groups), with larger responses associated with higher error rates and lower perceptual sensitivity. Results were suggestive of a predictive relationship between somatosensory reactivity and neuropsychological maturation. 相似文献
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强迫症患者认知功能与病期的关系 总被引:1,自引:1,他引:1
目的:探讨强迫症的认知功能障碍与病期的关系。方法:分别用韦氏记忆测验,数字划销测验和威斯康星卡片分类测验评估25例急性强迫症和36例慢性强迫症患者的记忆、注意和执行功能。结果:急性强迫症患者的记忆测验中记图和数字划销测验中第二阶段失误率显著性较慢性强迫症差,其余两组间记忆测验、划销测验和威斯康星卡片分类测验各量表分无显著性差异。结论:强迫症的认知功能与病期无明显相关。 相似文献
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Prof. Dr. J. Simões da Fonseca M. Teresa Gil M. Luisa Figueira J. Guerreiro Barata Fernando Pego M. Fernanda Pacheco 《European archives of psychiatry and clinical neuroscience》1978,225(1):31-53
Summary The authors studied the behavior of normal subjects and paranoid schizophrenic patients in a simple problem-solving situation. The schizophrenics were divided into two sample groups, one of individuals under treatment and the other of individuals not under treatment.The learning process involved in this problem-solving situation is very similar to an instrumental conditioning, and can be understood by means of the following assumptions: (1) the subjects use decision functions in reacting to the stimuli, although they may be not fully aware of this; (2) learning is the result of successive transformations of these decisions in the course of time; (3) the changes have specific probabilities and are related to (a) those responses which are made to the latest stimuli, and (b) a differential probability for decision functions which were effective, or only interrupted painful reinforcement, or were completely ineffective.In schizophrenics further factors of importance were (1) an inertia factor and (2) the rigidly continued use of unsuccessful or only partially successful decision criteria.The authors used a systems theory based on Galois field theory and a calculus of operators specifying three groups of subjects. A computer program based on these hypotheses was tested in a simulation experiment.The statistical evaluation of the results showed a congruence between the theoretical approach and the experimental data.This work was carried out with financial support from the Institute de Alta Cultura, Lisbon, between 1970 and 1974 相似文献
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目的:观察醒脑开窍针法对脑外伤(TB)I患者认知功能和日常生活能力影响。方法:将60例TBI认知功能障碍患者随机分为观察组(规范化醒脑开窍针法)、对照组(非规范化的醒脑开窍针法)。治疗前后分别采用神经行为认知状态检查表(NCSE)和改良的Barthel指数评定法(MB)I来评定2组患者的认知功能和日常生活能力。结果:观察组治疗前后比较,在定向能力、专注能力、复述能力、记忆能力、命名能力、计算能力方面上,差异有非常显著性或显著性意义(P〈0.01,P〈0.05);对照组治疗前后比较,在定向能力、复述能力方面上,差异均有显著性意义(P〈0.05);治疗后2组间比较,在专注能力、定向能力、复述能力、记忆能力方面上,差异有非常显著性或显著性意义(P〈0.01,P〈0.05)。2组MBI治疗前后比较,差异均有非常显著性意义(P〈0.01);治疗后2组间MBI比较,差异有显著性意义(P〈0.05)。结论:规范化的醒脑开窍针法能更有效地改善脑外伤后认知功能和日常生活能力。 相似文献