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41.
The contributions of the autonomic nervous system and the cardiac pacing cells in the development of heat-acclimation-induced bradycardia were analyzed, and the effect of heat acclimation on the chronotropic response of the heart to heat stress (40° C) was studied. Rats were acclimated at 34° C for 0, 5, 14, 30 and 60 days. Heart rate (HR) was measured in conscious animals, using chronic subcutaneous electrodes. Sympathetic and parasympathetic influences were studied by IP administration of 0.1 and 1 mg/100 g body weight atropine and propranolol respectively, while intrinsic HR (HRi) was measured following administration of both drugs simultaneously. The effects of carbamylcholine and norepinephrine on the beating rate of isolated rat atria were investigated to study pacemaker responsiveness to neutrotransmitters. Up to day 14 of heat acclimation, bradycardia was attained by tonic parasympathetic acceleration (18%) and temporal sympathetic withdrawal (0.8% on day 14), to compensate for the gradually augmented HRi (2.5% and 8% on days 5 and 14, respectively). Following long-term acclimation HRi declined below pre-acclimation rate. This was associated with resumed sympathetic activity (16% and 10% on days 30 and 60 respectively) while parasympathetic activity continued to be high (18%). Tachycardia, known to occur with severe uncontrolled body hyperthermia, was attenuated following heat acclimation by 42%. It was concluded that during the initial phase of heat acclimation bradycardia is achieved primarily by changes in autonomic influences, while following long-term acclimation, changes in the intrinsic properties of the pacing cells (HRi) and the autonomic system both play a role. 相似文献
42.
Ishiguro N Kanehisa H Miyatani M Masuo Y Fukunaga T 《European journal of applied physiology》2005,94(1-2):25-35
This study tested the hypothesis that, as compared to whole-body bioelectrical impedance (BI) analysis, segmental BI analysis can estimate lean body mass (LBM) more accurately in a population with a large difference in muscularity. In addition to whole-body BI, which determines impedance (Z) between the wrist and ankle, two segmental BI analyses which determine the Z value of every body segment in each of (1) the arms, legs and trunk (distal BI) and (2) the upper arms, upper legs and trunk (proximal BI) were applied to a group of 125 male athletes and 75 non-athletes. The subjects were divided into validation and cross-validation groups. Simple and multiple regression analyses were applied to (length)2/Z (BI index) values for the whole-body and each body segment, to develop the prediction equations of LBM measured using air-displacement plethysmography. In the validation group, the SE of estimation was similar in the whole-body (3.4 kg, 5.4%), distal (3.4 kg, 5.5%) and proximal BI (3.3 kg, 5.2%) analyses. However, the whole-body and distal BI analyses produced systematical errors in the estimates of LBM. Moreover, the residuals in the two methods significantly (P<0.05) correlated with the ratios of BI indices of the upper arms and upper legs to those of the arms and legs, respectively, calculated as variables approximating the relative development of lean tissues at the proximal area of limbs. On the other hand, the proximal BI analysis was validated and cross-validated. Thus, the accuracy of estimating LBM was similar in the whole-body and the two segmental BI analyses. However, the prediction equations derived from the use of the whole-body BI index and a combination of the arms, legs and trunk BI indices produced a systematical error relating to the difference between the limb segments in lean tissue development. 相似文献
43.
对合江县川南苗族 2 0 7例 (男 113,女 94 )青壮年进行 73项活体测量 ,结果显示 :川南苗族身材矮小 ,男女性身高平均为 15 4 5 6cm和 14 3 89cm ,83%受检者身高分类属矮或很矮 ;体部垂直高度均偏小。川南苗族偏瘦弱 ,其体部宽度、深度测量及围度测量均偏小 ,体质稍差。川南苗族头长偏小 ,头宽与头高相对较大 ,故 6 8%以上受检者为圆或超圆头型、阔头型也较狭头型为多、 75 %以上为高头型 ;面高与面宽均小 ,面高尤甚 ,75 %以上的受检者属阔或超阔面型 ;鼻部测量值均小 ,6 0 %的个体属中鼻型 ,属狭或超狭鼻型较阔鼻型的略多。两性间各项测量差异显著 ,但具共同体质特征。三年龄组比较青年组头面部与胸部测量值较成年组与壮年组小 ,表明其发育尚未终止 ,但因长度与宽度或长度与高度、宽度与高度均平行增长 ,故头型、面型、鼻型等均无显著差异而三组保持共同特征 相似文献
44.
Ujiie T 《Computers in biology and medicine》2003,33(3):227-237
Partial left ventriculectomy (PLV) was originally introduced as a new surgical approach by patients with an end stage of cardiac disease. Coronary artery bypass grafting (CABG) is a standard procedures used in cardiac surgery. Multichannel ECG (MECG) measurements and body surface mapping (BSM) were used to analyse the normalised beat amplitude power maps (BAM) that reflect an overall cardiac activity. The resulting BAMs show that the amplitude of cardiac signals decrease for approximately 30% after the PLV and stay in the same level during the postoperative monitoring interval while after CABG no significant changes in BAM have been observed. In addition the electrodes from the body surface area above the left ventricle, where surgery was performed, show significant changes in beat amplitudes. 相似文献
45.
We evaluated human physiological responses and the performance of manual tasks during exposure to severe cold (–25°C) at
night (0300–0500 hours) and in the afternoon (1500–1700 hours). Thirteen male students wearing standard cold protective clothing
occupied a severely cold room (–25°C) for 20 min, and were then transferred to a cool room (10°C) for 20 min. This pattern
of exposure was repeated three times, for a total time of exposure to extreme cold of 60 min. The experiments were started
either at 1500 hours or 0300 hours and measurements of rectal temperature, skin temperature, blood pressure, performance in
a counting task, hand tremor, and subjective responses were made in each condition. At the end of the experiment at night
the mean decrease in rectal temperature [0.68 (SEM 0.04)°C] was significantly greater than that at the end of the experiment
in the afternoon [0.55 (SEM 0.08)°C, P<0.01]. After the second cold exposure at night the mean increase in diastolic blood pressure [90 (SEM 2.0) mmHg] was significantly
greater than that at the end of the second cold exposure in the afternoon [82 (SEM 2.8) mmHg, P<0.01]. At the end of the second cold exposure at night, mean finger skin temperature [11.8 (SEM 0.8)°C] was significantly
higher than that at the comparable time in the afternoon [9.0 (SEM 0.7)°C, P<0.01]. Similarly for the toe, mean skin temperature at the start of the second cold exposure at night [25.6 (SEM 1.5)°C]
was significantly higher than in the afternoon [20.1 (SEM 0.8)°C, P<0.01]. The increased skin temperatures in the periphery resulted in increased heat loss. Since peripheral skin temperatures
were highest at night, the subjects noted diminished sensations of thermal cold and pain at that time. Manual dexterity at
the end of the first cold exposure at night [mean 83.7 (SEM 3.6) times·min–1] had decreased significantly more than at the end of the first cold exposure in the afternoon [mean 89.4 (SEM 3.5) times·min–1, P<0.01]. These findings of a lowered rectal temperature and diminished manual dexterity suggest that there is an increased
risk of both hypothermia and accidents for those who work at night.
Electronic Publication 相似文献
46.
目的 研究正常妊娠晚期人胎盘和胎膜水通道蛋白3(AQP3)的表达及分布.方法 收集5例正常足月妊娠剖宫分娩的胎盘和胎膜样本,用RT-PCR测定AQP3 mRNA在胎盘和胎膜组织中的表达;用Western印迹和免疫组织化学方法检测AQP3蛋白质水平在胎盘和胎膜的表达.结果 RT-PCR显示AQP3 mRNA在胎盘和胎膜组织均有表达.Western印迹结果显示胎盘组织在29 000左右有一特异性条带.免疫组织化学结果显示AQP3表达于合体滋养细胞,而在羊膜上皮细胞未见表达.结论 AQP3在胎盘母儿液体平衡中可能发挥重要作用. 相似文献
47.
The energetics of middle-distance running 总被引:3,自引:0,他引:3
J. R. Lacour S. Padilla-Magunacelaya J. C. Barthélémy D. Dormois 《European journal of applied physiology》1990,60(1):38-43
Summary In order to assess the relative contribution of aerobic processes to running velocity (v), 27 male athletes were selected on the basis of their middle-distance performances over 800, 1500, 3000 or 5000 m, during the 1987 track season. To be selected for study, the average running velocity
corresponding to their performances had to be superior to 90% of the best French
of the season. Maximum O2 consumption
and energy cost of running (C) had been measured within the 2 months preceding the track season, which, together with oxygen consumption at rest
allowed us to calculate the maximalv that could be sustained under aerobic conditions:
. The treadmill runningv corresponding to a blood lactate of 4 mmol·–1 (v
la4), was also calculated. In the whole group, C was significantly related to height (r=–0.43;P<0.03). Neither C nor
(with, in this case, the exception of the 3000 m athletes) were correlated to
. On the other hand,v
a max was significantly correlated to
over distances longer than 800 m. These
were also correlated tov
la4. Howeverv
la4 occurred at 87.5% SD 3.3% ofv
a max, this relationship was interpreted as being an expression of the correlation betweenv
a max and
. Calculation ofv
a max provided a useful means of analysing the performances. At the level of achievement studied,
sustained over 3000 m corresponded tov
a max. The shape of the relationship ofv/v
a max as a function of the duration of the event raised the question of a possible change in C as a function of v during middle-distance running competitions. 相似文献
48.
Wilson TE Johnson SC Petajan JH Davis SL Gappmaier E Luetkemeier MJ White AT 《European journal of applied physiology》2002,88(1-2):67-75
This study compared the effects of pre-exercise cooling with control water immersions on exercise-induced thermal loads derived
from steady-state submaximal exercise. Eight healthy male participants [mean (SEM) age 29 (1) years, maximal oxygen uptake
3.81 (0.74) l·min–1, and body surface area 1.85 (0.11) m2] took part in experiments that included 30 min of baseline data collection [ambient temperature 21.3 (0.2°C)], 30 min of
immersion in water to the level of the supra-iliac crest [water temperatures of 35.1 (0.3)°C for thermoneutral and 17.7 (0.5)°C
for precooled treatments], and 60 min of cycling exercise at 60% of maximal oxygen uptake. No significant differences were
noted during exercise in net mechanical efficiency, metabolic rate, O2 pulse, or ratings of perceived exertion between the two treatments. Precooling resulted in a significant negative body heat
storage during immersion and allowed greater heat storage during exercise. However, net body heat storage for the entire protocol
was no different between treatments. Cooling significantly lowered rectal, mean skin, and mean body temperatures as well as
more than doubling the exercise time until a 0.5°C rectal temperature increase was observed. The cooling trial significantly
delayed onset of sweating by 19.62 min and decreased sweat rate by 255 ml·h–1 compared to control. Thermal and sweat sensation scores were lower after the cooling treatment compared to control. These
data suggest that lower-body precooling is effective at decreasing body heat storage prior to exercise and decreases reliance
on heat dissipation mechanisms during exercise. Therefore, this unique, well-tolerated cooling treatment should have a broader
application than other precooling treatments.
Electronic Publication 相似文献
49.
Michael H. Stone Michael E. Rush Harry Lipner 《Pflügers Archiv : European journal of physiology》1978,375(2):147-151
The hormonal levels of the gonadotropins, the weight of selected organs and of the triceps surae as well as body composition were determined in Sprague Dawley rats at 3 and 6 weeks after intensive training with or without a methandrostenelone (Dianabol) supplement (0.35 mg/kg/day). The controls were sedentary rats of similar age and weight at the start of the experiment. The dianabol treated rats in the sedentary and exercise groups had a depression of plasma LH levels. There were no differences in body weight, specific gravity, lean body weight, fat or % fat between the two trained groups. Dianabol had no apparent effect on the measured parameters other than a depression of LH. 相似文献
50.
E. Obál Jr. G. Benedek A. Jancsó-Gábor F. Obál 《Pflügers Archiv : European journal of physiology》1979,382(3):249-254
Salivary thermolytic mechanism (weight of salivary glands, effect of desalivation on water intake and body temperature, grooming activity) as well as escape behaviour and reaction to heat pain were studied in capsaicin-desensitized and control rats exposed to various warm ambient temperatures. Body temperature of the desensitized rats increased more than the controls at all the ambient temperatures studied (32, 34 and 36°C); however, significant differences in the mechanism of salivary cooling were obtained only at 34 and 36°C. Central impairment of saliva spreading in desensitized rats seems evident. Complete surgical desalivation did not increase hyperthermia of control and desensitized animals in warm environments. Therefore other mechanisms, primarily vasodilatatory, must also be involved in the rat's thermolytic normal response. Although desensitized rats did not show a tendency to escape from the warm environment their response to heat pain was normal. In conclusion, it is suggested that heat perception in desensitized animals is impaired; however, the existence of some capsaicin-insensitive thermolytic mechanisms (prone extension of the body) cannot be excluded.Supported by the Scientific Research Council, Ministry of Health, Hungary /4-05-0303-04-2/0/ and MTA-OM-MÉM-EÜM 70.211/79 相似文献