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排序方式： 共有213条查询结果，搜索用时 31 毫秒
41.
目的 探讨脑安胶囊联合艾地苯醌片治疗急性脑梗死的临床疗效。方法 选取2020年1月—2021年12月湘潭医卫职院附属医院（湘潭市第三人民医院）收治的80例急性脑梗死患者,根据随机数字表法将80例患者随机分为对照组和治疗组,每组各40例。对照组患者口服艾地苯醌片,30 mg/次,3次/d。治疗组患者在对照组治疗的基础上口服脑安胶囊,0.8g/次,2次/d。两组患者连续治疗4周。观察两组的临床疗效,比较两组的功能综合评定量表（FCA）评分、美国国立卫生研究院脑卒中量表（NIHSS）评分、低灌注区面积以及血清抗心磷脂抗体（ACA）、趋化因子配体12(CXCL12)、基质金属蛋白酶8(MMP-8)水平。结果 与对照组（75.00%）相比,治疗组的总有效率（92.50%）更高,差异有统计学意义（P<0.05）。治疗后,两组的FCA评分显著增大,NIHSS评分显著减小（P<0.05）;治疗组的FCA评分高于对照组,NIHSS评分低于对照组,差异有统计学意义（P<0.05）。治疗后,两组的低灌注区面积均显著缩小（P<0.05）,治疗组的低灌注区面积明显小于对照组,差异有统计学... 相似文献
42.
目的 通过对前交通动脉复合体及其穿支动脉的显微解剖，为降低手术夹闭前交通动脉瘤的穿支动脉相关并发症提供解剖学依据。 方法 选取15具（30侧）尸头，充分暴露大脑前动脉A1段及前交通动脉复合体，显微镜下观察并测量各区域穿支动脉的数量、起始管径及分布区域等。将A1段按长度平均分为6区（A~ F区），观察6区穿支动脉的分布特点，寻找最佳临时阻断区。选取动脉内红色乳胶灌注充盈良好的10具尸头，显微镜下观测A1段髓质支及Heubner回返动脉自皮质至髓质的深度及分布区域。 结果 大脑前动脉A1段长度为（15.13±4.76）mm，其发出穿支动脉共244支，其中A区63支（25.82%），B区54支（22.13%），C区51支（20.90%），D区31支（12.70%），E区20支（8.20%），F区25支（10.25%）。大脑前动脉A1段与A2段长度、穿支动脉数量及穿支动脉起始外径左右均无明显差异。 结论 熟悉前交通动脉复合体及其穿支动脉的解剖学特点是术中减少或避免穿支动脉损伤的关键。A1段E区常可作为最佳临时阻断区。 相似文献
43.
Self‐assessed health is one of the most commonly used health measures by economists. However, changes in self‐assessed health are not always accompanied by changes in physical health as measured by clinical outcomes. This study provides suggestive evidence that this discrepancy arises because self‐assessed health is significantly influenced by psychological factors. Specifically, when the perceived risk of Affordable Care Act (ACA) repeal increased, as documented by Google Trends data, self‐assessed health declined among low‐income childless adults living in states that expanded Medicaid under the ACA. 相似文献
44.
45.
目的：探讨糖尿病微血管病变（DMA）患者血栓前状态标志物的改变及与自身抗体产生的关系。方法：采用免疫比浊法测定血浆纤维蛋白原（Fbg），酶联免疫吸附法（ELISA法）测定血浆中外周血浆因子Ⅷ相关抗原（VWFAg）、D-二聚体（（D-D）和抗心磷酯抗体（ACA）在DMA组、糖尿病无微血管病变组和正常组中的含量。结果：DMA组血浆中血栓前状态标志物Fbg、VWFAg及D-D和自身抗体ACA的水平明显高于糖尿病无微血管病变组和正常组（P〈0．05或P〈0．001），ACA水平的增高与Fbg、VWFAg及D-D水平的增高呈正相关，且ACA在DMA组中的阳性率显著高于糖尿病无微血管病变组和正常组（P〈0．05）。结论：糖尿病患者存在着凝血和纤溶功能的改变，在DMA时Fbg、VWFA、D-D等血栓前状态标志物增高更明显，与血栓形成密切相关的自身抗体ACA在DMA时的阳性率明显增高，且与Fbg、VWFA、D-D的增高呈正相关。因此，检测DMA患者的Fbg、VWFA、D-D和ACA水平对预防和治疗血栓形成及预后判断具有一定的临床意义。 相似文献
46.
S.H. Min T.J. Oh S.-I. Baek D.-H. Lee K.M. Kim J.H. Moon S.H. Choi K.S. Park H.C. Jang S. Lim 《Diabetes & metabolism》2018,44(1):73-76
Background
Euglycaemic ketoacidosis has been reported after sodium–glucose cotransporter 2 (SGLT2) inhibitor treatment. However, the degree of ketonaemia and its metabolic effects have not been well investigated. Our study examined the degree of ketonaemia induced by SGLT2 inhibition and its association with metabolic profiles in type 2 diabetes mellitus (T2DM).Methods
Biochemical parameters, including insulin, glucagon, free fatty acid (FFA), β-hydroxybutyrate (BHB) and acetoacetate (ACA) levels, were measured in 119 T2DM patients after dapagliflozin treatment for > 3 months, and compared with a matched control group.Results
Levels of total ketones, BHB and ACA were significantly higher in the dapagliflozin group than in the control group: 283.7 ± 311.0 vs 119.8 ± 143.8 μmol/L; 188.3 ± 226.6 vs 78.0 ± 106.7 μmol/L; and 94.1 ± 91.3 vs 41.8 ± 39.1 μmol/L, respectively (all P < 0.001). After dapagliflozin treatment, BHB was higher than the upper limit of normal (> 440 μmol/L) in 13 (10.9%) patients who had no relevant symptoms. BHB level after dapagliflozin treatment correlated positively with HbA1c (r = 0.280), FFA levels (r = 0.596) and QUICKI (r = 0.238), and negatively with BMI (r = ?0.222), insulin-to-glucagon ratio (r = ?0.199) and HOMA-IR (r = ?0.205; all P < 0.05). On multivariable linear regression analysis, QUICKI was independently associated with BHB level.Conclusion
Ketone levels were higher in T2DM patients treated with dapagliflozin than in controls, but with no clinical symptoms or signs of ketonaemia. Low-grade ketonaemia after dapagliflozin treatment may also be associated with improved insulin sensitivity. 相似文献47.
Dental plan premiums in the Affordable Care Act marketplaces trended downward from 2014 through 2016
Background
Pediatric dental benefits must be offered in the health insurance marketplaces created under the Affordable Care Act. The authors analyzed trends over time in premiums and the number of dental insurers participating in the marketplaces.Methods
The authors collected dental benefit plan data from 35 states participating in the federally facilitated marketplaces in 2014, 2015, and 2016. For each county, they counted the number of issuers offering stand-alone dental plans (SADPs) and medical plans with embedded pediatric dental benefits. They also analyzed trends in premiums.Results
From 2014 through 2016, the number of issuers of stand-alone dental plans and medical plans with embedded pediatric dental benefits either did not change or increased in most counties. Average premiums for low–actuarial-value SADPs declined from 2014 through 2016.Conclusions
The increase in the number of issuers of stand-alone dental plans and medical plans with embedded dental benefits may be associated with lower premiums. However, more research is needed to determine if this is the case.Practical Implications
Affordable dental plans in the marketplaces could induce people with lower incomes to sign up for dental benefits. Newly insured people could have significant oral health needs and pent-up demand for dental care. 相似文献48.
49.
Shulamite S. Huang 《Journal of the American Dental Association (1939)》2018,149(12):1049-1056.e1
Background
Previous study results have indicated that the Patient Protection and Affordable Care Act (ACA) health insurance expansion for dependents (called the dependent coverage expansion) also led to a dental insurance expansion for dependents. In this study, the author examines whether this expansion is due to changes in employer-sponsored dental insurance.Methods
The author compared enrollment and oral health care use between 2 groups of young adults in employer-sponsored dental plans managed by Delta Dental of Michigan before and after the initial implementation of the ACA: adults aged 20 through 24 years (eligible for the expansion) and adults aged 30 through 34 years (ineligible).Results
The ACA dependent coverage expansion led to an increase in both dental plan enrollment rates (5.38%; P < .01) and oral health care use rates (3.57%; P < .1) among adults aged 20 through 24 years relative to adults aged 30 through 34 years.Conclusions
Although the ACA’s dependent coverage expansion led to an increase in dental plan enrollment and oral health care use in Michigan, the effects seen by other insurers and states are yet to be determined, although the direction likely is similar.Practical Implications
This study’s results suggest that employers responded to the ACA dependent coverage expansion by expanding dependent oral health care coverage. 相似文献50.