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71.
患者男,53岁。颈部丘疹20年余,无自觉症状,也无甲状腺功能异常。皮损组织病理示:真皮中上部胶原纤维稀疏,其内充满均质性无定形物质。阿新蓝染色阳性。诊断:皮肤局灶性黏蛋白病。 相似文献
72.
Glória C. Velho Manuela Oliveira Rosário Alves Frederico Silvestre António Massa A. Poiares Baptista 《Journal of the European Academy of Dermatology and Venereology》1998,10(2):164-166
A case of childhood cutaneous mucinosis is described. This is a clinical condition that is rarely seen and has only recently been included in the group of primary mucinosis. 相似文献
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报道1例生殖器丘疹样棘层松解性皮病.患者,男,30岁.2年前肛周出现灰白色丘疹,部分融合,伴瘙痒.实验室检查:HPV6阳性,醋酸白试验、梅毒螺旋体明胶凝集试验(TPPA)、HIV均阴性.皮损组织病理示:基底层上方棘层下方多处裂隙,可见棘层松解细胞,中等量淋巴细胞浸润.直接免疫荧光:IgG、IgM、IgA、C3阴性.予以... 相似文献
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We report a patient with the typical lesions of diabetic scleredema. Histological findings of the involved skin were thickening of the dermis, depositions of mucins, and fibrosis. Biochemical analysis revealed an increase in glycosaminoglycans in the involved skin as well as in the cutaneous lupus mucinosis. Mucinous materials were composed of hyaluronic acid. 相似文献
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Giuseppe Noto Gabriella Pravatà Mario Aricò 《Journal of the European Academy of Dermatology and Venereology》1996,7(3):247-251
A whitish, indurated, oval plaque, lasting for 1.5 year, was observed in the right paraumbilical skin of a middle-aged man in otherwise good health. No erythema was present or referred. Histological examination revealed massive deposits of a globular, slightly basophilic, amorphous substance in the dermis, accompanied by a slight perivascular mononuclear cell infiltrate and scattered mast cells. Special staining with Alcian blue at pH 2.5 confirmed the intense deposition of mucin involving the entire dermis. sparing epidermis, adnexa and perivascular areas. No abnormal laboratory results indicating lupus erythematosus or thyroid dysfunction were present. Morphea was excluded on clinical and histological grounds. A plaque-like form of cutaneous mucinosis was diagnosed. Plaque-like mucinosis and reticular erythematous mucinosis (REM) syndrome are currently considered to be the same disease, although some authors noted a different response lo treatment. Clinical presentation of our case was unusual: no erythema preceded or accompanied the plaque growth, which had a whitish, indurated, morphea-like appearance from the beginning but with preservation of hair follicles, quite different from archetypical REM syndrome based on clinical grounds. 相似文献
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Hyaluronan in skin 总被引:1,自引:0,他引:1
L. Juhlin 《Journal of internal medicine》1997,242(1):61-66
Juhlin L (University Hospital, Uppsala, Sweden). Hyaluronan in skin (Minisymposium: Hyaluronan) J Intern Med 1997; 242 : 61–6.
Because of the abundance of hyaluronan in skin, interest was early focused on variation in the content of the polysaccharide in various pathological conditions of this tissue. A large amount of early work utilized histological techniques of insufficient specificity but recent developments of specific analytical and staining methods for hyaluronan have supplied new data on its presence and possible role in skin disorders. 相似文献
Because of the abundance of hyaluronan in skin, interest was early focused on variation in the content of the polysaccharide in various pathological conditions of this tissue. A large amount of early work utilized histological techniques of insufficient specificity but recent developments of specific analytical and staining methods for hyaluronan have supplied new data on its presence and possible role in skin disorders. 相似文献