淋病患者泌尿生殖道沙眼衣原体和尿素分解尿素原体的检测结果和分析

本文通过对430例淋病患者泌尿生殖道的沙眼在原体、尿素分解尿素原体的检测，发现淋病患者中有19．8％的病人合并在原体的感染，17．2％的病人合并支原体的感染，尚有5．5％的病人同时感染衣原体和支原体；提示临床中应重视对淋病患者中非淋的检测，以便减少误诊，提高临床治愈率。     

柳州地区淋病患者支原体感染频率及分布特点的研究

对180例淋病患者和205名健康人的血清用IHA法进行了人型支原体(Mh)抗体检测。结果表明,淋病患者Mh抗体阳性率为18.89%,GMT为1:6.60;健康人阳性率为4.39%。GMT为1:4.53。病人的抗体水平显著高于健康人(P<0.01)。提示我国大陆地区存在Mh引起的泌尿生殖道感染。     

头孢克肟颗粒治疗小儿急性淋球菌性尿道炎疗效观察

目的探讨头孢克肟颗粒治疗小儿泌尿系统急性淋球菌感染的临床效果。方法将兰州大学第二医院泌尿外科2013年5月至2015年5月间共诊治的34例淋病患儿,口服头孢克肟颗粒进行治疗,观察疗效和不良反应。结果 34例患儿痊愈31例(91.18%),显效3例(8.82%),总有效率为100%。有1例患儿在服药期间有轻微腹泻、食欲差等不适。结论头孢克肟颗粒治疗小儿泌尿系统急性淋球菌感染临床疗效好、起效快、不良反应少,具有高效性和安全性。     

男性尿道感染病征指标诊断淋菌性和非淋菌性尿道炎的信度及效度评价

目的　评价常见男性尿道感染病征诊断淋菌性尿道炎 (GU)、非淋菌性尿道炎 (NGU)的真实性 (效度 )及可靠性 (信度 ) ,为今后此类诊断提供依据。方法　记录患者就诊时尿道口潮红、粘脓性分泌物、稀脓性分泌物、尿道不适、尿频尿急 5项病征指标 ,同时用培养法检测淋球菌、解脲支原体 (UU)和人型支原体(MH) ,用抗原检测法检测衣原体 (CT) ,并对结果进行分析。结果　尿道不适、粘脓性分泌物对于GU的诊断具有较高敏感性 ,粘脓性分泌物信度最高。尿道口红及稀脓性分泌物诊断NGU的效度及信度均较高。结论　粘脓性分泌物及尿道口红、稀脓性分泌物和尿道口红分别为诊断GU及NGU的重要指标 ,有助于临床进行病征处理。     

Evidence against the "booty pack": Trichomonas not associated with gonorrhea or Chlamydia

Many Emergency Physicians armed with a positive Trichomonas wet mount will also treat for Neisseria gonorrhea (GC) and Chlamydia trachomatis (CT). This study estimates the association between Trichomonas microscopy result and a DNA test result for GC or CT. Using laboratory records from patients who had simultaneous sampling for all three infections, we calculated an odds ratio for the association between the Trichomonas result and a positive test for either GC or CT. Among 795 eligible females, 105 (13%) had Trichomonas, 74 (9%) had CT, and 35 (4%) had GC. Whereas CT and GC were strongly associated with each other (odds ratio 5.9, 95% confidence interval 2.8–12.4, p < 0.0001), Trichomonas infection was unrelated to infection with either GC or CT (odds ratio 1.1, 95% confidence interval 0.6–2, p = 0.9). Trichomonas results do not predict results for GC and CT; they should not influence the decision to treat for GC and CT.     

淋病后慢性前列腺炎患者病原体检查分析

目的研究淋病后慢性前列腺炎的致病菌及其耐药性,探讨其发病原因及治疗和预防的方法。方法采用前列腺液普通细菌培养和STD系列检查。结果淋病后慢性前列腺炎以金黄色葡萄球菌和表皮葡萄球菌为主要感染菌,同时也有支原体和衣原体的感染。结论淋病治疗前脓性分泌物全面的病原体分析,合理并正规地使用抗生素,对提高治愈率、控制耐药菌株的产生无疑是治愈淋病及其并发症的关键。     

88例淋病患者耐药性分析

目的：检测淋病患者的耐药性。方法：收集2016年9月至2018年12月我院性病门诊淋病患者,利用E-test法测定青霉素、四环素、环丙沙星、大观霉素、头孢曲松、头孢克肟和阿奇霉素七种抗生素的最小抑菌浓度(MIC)。结果：共收集淋病患者88例,男77例,女11例。环丙沙星耐药86例（97.73%）,青霉素耐药63例（71.59%）,四环素耐药54例（61.36%）,阿奇霉素耐药17例（19.32%）,头孢克肟耐药1例（1.14%）,大观霉素和头孢曲松无耐药。结论：头孢曲松、头孢克肟和大观霉素仍为治疗淋病的首选药物。     

小儿淋病51例回顾性分析

目的探讨小儿淋病的临床特点及传播途径。方法采用回顾分析方法对51例小儿淋病患者的临床特点及传播途径进行分析。结果男12例,女39例,男女比为1:3.25,其中伴新生儿淋菌性结膜炎3例;0~1岁组者最多,为21例(41.18%),其次为5~10岁组17例(33.33%);1~5岁者居第三,为11例(21.57%);幼女发病率较高,占76.47%。患儿全为间接感染,38例患儿为家庭内感染,如父母、保姆,也有亲戚及托儿所等,有些感染途径不详。结论婴幼儿的淋病发病趋于增高,传染源呈多样性,来自保姆及私立托儿所(特别是乡村托儿所)的感染值得关注。     

A Meta‐analysis of the Efficacy of Ocular Prophylactic Agents Used for the Prevention of Gonococcal and Chlamydial Ophthalmia Neonatorum

Introduction : Neonatal eye prophylaxis has been routine in North America for more than a century. Contextual changes justify reexamining this practice, and prompted a systematic review of the efficacy of prophylactic agents. Methods : We searched MEDLINE (1966–2008), EMBASE (1980–2008), CINAHL (1982–2008), and the Cochrane library (the first quarter of 2008) for relevant clinical trials and hand‐searched the resulting reference lists. We independently evaluated eligibility and study quality. Meta‐analyses were performed using a random effects model. Results : Each of the eight included studies had substantial methodologic weaknesses. Data to estimate the efficacy of prophylaxis in the prevention of gonococcal ophthalmia neonatorum (GON) were not available. One study found no differences in rates of chlamydial ophthalmia neonatorum (CON) when three agents were compared to no prophylaxis: silver nitrate (relative risk [RR] = 1.06; 95% confidence interval [CI], 0.55–2.02; 2225 newborns), erythromycin (RR = 0.93; 95% CI, 0.48–1.79; 2306 newborns), and tetracycline (RR = 0.82; 95% CI, 0.42–1.63; 2299 newborns). No statistically significant differences were found between agents in the prevention of GON. Erythromycin and povidone‐iodine both decrease the risk of CON when compared to silver nitrate (RR = 0.71; 95% CI, 0.52–0.97; 4514 newborns, and RR = 0.52; 95% CI, 0.38–0.71; 2005 newborns, respectively). Discussion : Failure rates of universal eye prophylaxis support reexamination of this policy where the prevalence of maternal infection is low.