Validation of a French health-related quality of life instrument for adolescents: The VSP-A

The French Health Ministry, stating the limits of traditional indicators to take into account the different aspects of adolescent health, declared adolescent health status assessment as a priority. Thus a French health-related quality of life (HRQL) generic self-administered indicator was developed on the adolescent's viewpoint for healthy and ill adolescents of 11–17: the VSP-A, Vécu et Santé Perçue de l'Adolescent, intended to be used as a discriminative, predictive and evaluative instrument. This paper reports the validation study of the 40-item VSP-A including 2941 adolescents. Six dimension scores were computed: psychological well-being, energy, friends, parents, leisure, school, as well as an index. Content and construct validity were confirmed. Factorial validity was shown. As expected, scale scores were significantly associated with a one-item global well-being visual analogue scale (r = 0.53; p < 0.001) and with a self-esteem score (r = 0.62; p < 0.001). On the VSP-A index, girls and older adolescents were found to have the lowest scores. The VSP-A is reliable in terms of internal consistency (Cronbach's = 0.83) and test–retest results (r = 0.69; p < 0.001). The ability of VSP-A, filled in less than 15 min, was shown to discriminate between ill and healthy adolescents, and to predict an impairment of their health status. The next phase of the research involves testing in various populations and more specifically in populations with diverse acute and chronical health conditions, so as to refine the content of the instrument and to add much to what is known about the sensitivity to changes of the VSP-A scores in patients who are under treatment.     

A case-control study on alcohol and seizures: study design, protocol, and data collection

We designed a multicenter case control study to evaluate whether chronic alcoholism and alcohol consumption are risk factors for developing a first generalized tonic-clonic epileptic seizure. Cases were 278 patients (92 women, 186 men), with a first generalized tonic-clonic seizure (either idiopathic or symptomatic), matched to 556 controls for center, sex, age, and weekday of the seizure. Information on risk factors was obtained through a questionnaire. This paper focuses on the study design (selection of cases and choice of controls), the validity of the instruments for data collection, and the strategies of study conduction (interviews, use of proxy respondents). Inter-rater agreement was excellent for drinking status, patterns of drinking, and broad indicators of consumption (yes/no). Agreement was variable for the number of servings/week, but was excellent (r=0.91) for a summary measure of daily alcohol intake.Members of the ALC.E. Group:Sironi L.,U.O. di Neurologia, Ospedale Regionale, Aosta; Brignolio F., Duc E., Montano V., Tribolo A.,Divisione di Neurologia, Ospedale Civile, Asti; Nardozza V., Gionco M.,Divisione di Neurologia, Ospedale degli Infermi, Biella; Grasso E., Meineri P., Rosso M.G.,Divisione di Neurologia, Ospedale Santa Croce, Cuneo; Villani A., Margaroli A., Julita P., Savoini G.,Divisione di Neurologia, Ospedale S. Biagio, Domodossola; Cavalli A., De Angelis M.S., Naldi P., Terazzi E., Tinebra M.,Divisione Universitaria di Neurologia, Facoltà di Medicina e Chirurgia di Novara, Università di Torino; Campanella A., De Mattei M., Rocci E., Zaina P.,DEA di Neurologia, Ospedale Molinette, Torino; Nobili M., Vivalda L., Leotta D., Morino U.,Divisione di Neurologia, Ospedale Martini, Torino; Bacci R., Daniele D.,Divisione di Neurologia, Ospedale Mauriziano, Torino; Rubino R., Provera P.,Divisione di Neurologia, Ospedale Civile, Tortona; Andreotti M., Mittino D.,Divisione di Neurologia, Ospedale SS. Trinità, Varallo Sesia.     

中医体质量表应用于术后恶心呕吐风险评估的信度和效度分析

【目的】分析中医体质量表的信度和效度。【方法】采用中医体质量表对2013年3月至10月期间符合入组标准的450例女性妇科腹腔镜手术术后恶心呕吐(PONV)患者的体质类型进行了评价,采用Cronbach’sα系数和因子分析初步分析了量表的信度和效度。【结果】184例(40.9%)女性腹腔镜手术PONV患者兼夹2种及以上偏颇体质,阳虚质和气郁质2个分量表具有较好的内部一致性(Cronbach’sα系数分别为0.815和0.803),平和质最低(Cronbach’sα系数为0.514);因子分析提取9个公因子累计方差解释度仅为48.5%。【结论】中医体质量表还需要结合实际应用后的反馈加以修订。     

中医气虚体质影响因素的性别差异分析——基于22 332例一般人群数据

[目的]探讨中医气虚体质影响因素的性别差异。[方法]应用已建立的健康状况调查数据库中的22 332例数据进行研究。样本数据来自中国江苏、安徽、甘肃、青海、福建、北京、吉林、江西、河南、广东10个省市。采用中医体质量表的气虚质亚量表对气虚体质进行评价。应用单因素分析和多元逐步回归分析法探讨不同性别人群的气虚体质得分影响因素。[结果]多元逐步回归分析结果显示,按照标准回归系数（绝对值）大小从高到低依次排序,影响男性气虚体质评分的因素为有慢性疾病、不太运动、出生后非母乳喂养、婚况因素（未婚）、喜热、喜咸、喜冷（凉）、喜清淡、喜甜饮食;女性为有慢性疾病、不太运动、喜热饮食、出生后非母乳喂养、喜清淡、喜甜饮食。其中共同的影响因素为有慢性疾病、不太运动、出生后非母乳喂养、喜热、喜清淡、喜甜饮食;不同因素为婚况因素（未婚）、喜咸、喜冷（凉）饮食。[结论]不同性别人群的气虚体质得分影响因素虽大致相同,但又有其不同特点。在进行气虚体质调节时,应对性别加以区分。     

The association between pain catastrophising and kinesiophobia with pain and function in people with plantar heel pain

BackgroundPsychological variables, including catastrophic thoughts and kinesiophobia, are common in people with chronic musculoskeletal pain and are associated with pain and function. However, the role of each factor has not been evaluated in people with plantar heel pain (plantar fasciitis).MethodsThirty-six participants diagnosed with plantar heel pain were recruited. Main outcome measures included the Pain Catastrophising Scale, Tampa Scale of Kinesiophobia, the Foot Health Status Questionnaire and a Visual Analogue Scale. Hierarchical regression models were developed to evaluate the association between each psychological variable with variations in foot pain, first step pain and foot function.ResultsIn a full model with age, sex and BMI, kinesiophobia contributed to 21% of the variability in foot function and was a significant predictor in this model (Beta = −0.49, P = 0.006). In a separate model, catastrophising explained 39% of the variability in foot function and was a significant predictor in this model (Beta = −0.65, P < 0.001). Finally, pain catastrophising accounted for 18% of the variability in first step pain and was a significant predictor in a model that also included age, sex and BMI (Beta = 0.44, P = 0.008).ConclusionsAfter controlling for age, sex and BMI, kinesiophobia and catastrophising were significantly associated with foot function, while catastrophising was associated with first step pain in people with plantar heel pain. In addition to addressing biological factors in the management of plantar heel pain, clinicians should consider the potential role of pain catastrophising and kinesiophobia in this population.     

医护人员高危药品风险因素认知调查

摘 要 目的：对高危药品的安全性进行问卷调查, 全面梳理和挖掘工作中存在的风险因素。 方法：采用便利抽样法选取镇江市18 家二级以上医疗机构的医护人员260 人作为研究对象, 主要从医院及填表人员基本信息,高危药品知识,高危药品管理及使用情况等三方面开展问卷调查并分析。结果：共发放问卷260份, 回收有效问卷236份,有效回收率达90.77%。 调查结果显示,高危药品临床使用过程存在认知度不高、制度不规范、管理不严谨、缺乏培训等问题。结论：我市医疗机构还须加强高危药品风险管理, 以及进一步加强药品不良反应监测。     

主观记忆障碍量表在社区老年人中的信效度评价

目的对主观记忆障碍量表（SMCQ）进行汉化,并检测其信效度。方法采用方便抽样法,运用SMCQ 对356 名农村社区老年人进行问卷调查,运用SPSS23.0 和AMOS23.0 软件对所得数据进行统计分析。结果条目相关性分析结果显示,所有条目- 总分均有相关性,探索性因子分析得到三因子结构方程模型,累计方差贡献率为65.442%,验证性因子分析得到χ2/ 自由度（CMIN/DF）<3、渐进残差均方和平方根（RMSEA）<1.00、非规范拟合指数（TLI）、增值拟合指数（IFI）、比较拟合指数（CFI）均>0.90,简约拟合指数（PGFI）>0.50,除CMIN、GFI 和AGFI 外,均达到适配标准;SMCQ 的Cronbachα系数为0.872,分半信度为0.757。结论SMCQ信效度良好,可用于我国社区老年人主观记忆障碍状况的评价。     

广州农村地区学龄前儿童重度龋患病现状及其影响因素

目的 了解广州市农村地区学龄前儿童重度龋患病现状,探讨其影响因素,为制定针对性的防控措施提供依据.方法 选择广州市番禺区化龙镇和新造镇农村3～6岁学龄前儿童,向其家长发放调查问卷,调查儿童基本情况、家庭饮食卫生习惯、家庭情况,并进行龋齿检查.结果 回收有效问卷755份,有效率94.38％,学龄前儿童患龋365例,患龋率48.34％(365/755),其中重度龋167例,占22.12％(167/755).Logistic多因素分析结果显示,睡前进食后未刷牙、喝含糖饮料、每次刷牙用时短、看护人咀嚼喂食等是学龄前儿童重度龋的危险因素,家长帮助或监督孩子刷牙是重度龋的保护因素.结论 广州农村地区学龄前儿童重度龋患病率较高,应重点培养睡前刷牙、少喝含糖饮料、刷牙用时不少于3 min的卫生习惯,并指导看护人不咀嚼喂食、家长监督孩子刷牙,以降低重度龋发生率.     

基于问卷调查探讨药事服务费的实施及互联网药事服务的前景

摘 要 目的：了解民众对药事服务的相关看法,探讨我国药事服务费的实施及互联网药事服务的前景。方法: 对来院就诊患者及其亲属进行药事服务费及互联网药事服务相关的问卷调查,问卷回收后对问卷回收情况、被调查者信息及答题情况进行统计。结果: 被调查者中63.8%认为收取药事服务费是合理的,大多数人认为该费用主要由政府财政和医保承担,85.5%认为互联网药事服务是必要的,其服务内容包括网上售药、药师咨询、用药教育、中药代煎、药品配送等,尤其认为药师咨询最为必要。结论:门诊患者对药事服务的需求较高,且大多认同网上药事服务,但对其认识不一。设立药事服务费是顺应医药行业发展的必然趋势,相关部门还需进行足够的宣传和引导工作,提高民众对药事服务的认同度及对其费用的接受度;合理利用互联网优势,多元化提供药事服务,提高药学服务水平、促进合理用药。