改良点式剥脱术治疗下肢浅静脉曲张临床报告

目的：评估改良点式剥脱术治疗下肢浅静脉曲张的临床疗效。方法：摒弃输精管钳改用蚊式钳，术中采用弹拔法寻找静脉，准确快捷，副损伤小。结果：采用改进术式治疗198例共208条肢体，经近10年随访疗效良好。结论：在现阶段改良点式剥脱术是较为实用简便的治疗方式。     

STANDARD IMAGING TECHNIQUES OF ENDOSCOPIC ULTRASOUND‐GUIDED FINE‐NEEDLE ASPIRATION USING A CURVED LINEAR ARRAY ECHOENDOSCOPE

Standard imaging techniques using a curved linear array echoendocope are summarized to facilitate the attainment of expertise in endoscopic ultrasonography and endoscopic ultrasound‐guided fine needle aspiration, and to promote the widespread use of this diagnostic and therapeutic tool. Typical images of the mediastinal organs, the bilio‐pancreatic systems and neighboring organs by scanning from the esophagus, stomach, duodenal bulb, and descending portion of the duodenum, are shown in a sequential manner. The basic techniques of endoscopic ultrasound‐guided fine needle aspiration are also presented.     

Selective parity RARE imaging.

This work describes a novel method for rapid acquisition with relaxation enhancement (RARE)/fast spin-echo (FSE) imaging that removes the constraint of compliance with the Carr-Purcell-Meiboom-Gill (CPMG) condition. In a multiecho sequence, echoes with either odd or even parities are acquired. The refocusing angles are chosen using a recursive algorithm, so that the signal amplitude satisfies a predetermined modulation function. In the examples given in this article an exponential decay to a plateau is used. At each echo the echo parity that gives the desired signal amplitude for the minimum refocusing angle is selected. It is further shown that in the presence of an initial magnetization having an arbitrary phase distribution, the complex conjugate of the signal of one echo parity has to be taken and its k-space coordinates reversed. T(2) (*)-weighted images are presented and initial applications to diffusion-weighted imaging (DWI) and functional imaging shown.     

吸附澄清法在中药水提液澄清中的应用研究

采用吸附澄清法使中药水提液澄清,从工艺稳定性,成分分析,药效学实验及效益分析四方面分析了两种工艺,吸附澄清法同水提醇沉法相比,能更有效地保留中药总固体物含量及有效成分,提高制剂成品的内在质量;成品稳定性好;成本低;生产周期短;劳动强度低,可望产生良好的社会经济效益。     

农村已婚育龄妇女节育措施落实状况调查

<正> 计划生育工作的重点在农村。为了解农村妇女节育措施落实情况,提高节育、避孕率及避孕效果,     

Progressive peri‐implantitis. Incidence and prediction of peri‐implant attachment loss.

The aim of this prospective study was to characterize an implant patient population exhibiting clinical signs of peri‐implantitis and to determine subsequently the incidence of progressive attachment loss. The predictive values of diagnostic parameters were evaluated. 25 patients with 54 endosseous implants that had been loaded for 41±15 months were included in the study. Clinical parameters included the assessment of plaque, bleeding on probing, probing depth, attachment levels, and Periotest® values. Probing measurements were performed in duplicate by means of a controlled force electronic probe (Periprobem). Peri‐implant crevicular fluid samples were collected and assayed for neutral proteolytic enzyme (NPE) activity (Periocheck®). Analysis of duplicate baseline probing data revealed a high degree of reproducibility (mean difference: 0.1±0.3mm). A minimum threshold of 1.0mm (>3×S.D.) loss of probing attachment was chosen to classify a site as positive for breakdown. Alternatively, the tolerance method was employed to identify sites with progressive attachment loss. After 6 months, irrespective of the analytical method, 6 percent of all sites (in 19% of the implants) and 28% of the patients had experienced further per attachment loss. There were significant differences ( p <0.05) in mean plaque (73% vs. 45%) and NPE (36% vs. 12%) scores between patients with progressive peri‐implantitis and those with stable peri‐implant conditions. Both bleeding on probing and the NPE‐test were characterized by high negative predictive values, and thus negative scores can serve as indicators for stable peri‐implant conditions. For monitoring peri‐implant health during recall visits, attachment level recordings with a controlled force electronic probe in conjunction with enzymatic diagnostic tests of the host response can be recommended.     

地榆鞣质抗肝癌细胞SMMC—7721的MTT及FCM分析

探讨中药成分地榆鞣质的抗癌活性，并试图建立一种筛选抗癌药物的方法，方法：运用ＭＴＴ法测定ＳＴＭ及ＳＴＬ对体外培养人肝癌ＳＭＭＣ－７７２１细胞的杀伤率并通过流式细胞仪分析细胞分裂周期各时象ＤＮＡ变化。结果；ＳＴＭ与ＳＴＬ均有明显抗癌活性，与阴性对照组相比有显著差异，并具有剂量效应关系，ＳＴＭ，ＳＴＬ与ＭＭＣ联合用药抗癌活性增强，与单独用药组相比差异显著；     

附子理中丸方药的药物动力学研究

附子理中丸是中医治疗脾胃虚寒、脘腹冷痛、呕吐泄泻、手足不温的常用成药。本文通过小白鼠急性死亡实验,测得ip LD_(50)=42.4870g/kg;运用药物累积法对该复方方药进行了药物动力学研究。结果表明:附子理中丸在小鼠体内按一级动力学消除,呈二房室开放式模型分布。测得其t_(1/2)α=0.1922h,t_(1/2)β=11.2888h等动力学参数。阐明了该药的体内动态过程,为评价该药的内在质量及临床安全合理应用提供了参考依据。     

颅颌面形态有限元分析系统的初步建立

初步建立一个用于颅颌面形态变化研究的有限元分析系统。方法：程序用ＢｏｒｌａｎｄＣ语言编写，对临床常用的Ｘ线头颅定位片进行分析，将呆分析的头颅定位片描在硫酸纸上，用图形数值化仪把节点输入计算机。根据有限元分析法的原理，将头颅定位片上的颅颌面结构份割许多三角形单元，用应变张量来描述颅颌面形态变化。     

建立模拟功能状态下的下颌骨三维有限元模型

本文在三维影像重建和三维有限元分析技术的基础上，建立了正常人和颞下颌关节疾病患者正中咬合时下颌骨的三维有限元模型。下颌骨螺旋ＣＴ和有限元模型三维重建影像的几何相似性良好，加载方式符合生理状况，比较真实地反映和模拟了功能状态下颞下颌关节与牙合的受力情况。为对颞下颌关节在各种状况下的生物力学行为进行分析和研究创造了条件。