全文获取类型
收费全文 | 26334篇 |
免费 | 1887篇 |
国内免费 | 544篇 |
专业分类
耳鼻咽喉 | 200篇 |
儿科学 | 469篇 |
妇产科学 | 154篇 |
基础医学 | 3975篇 |
口腔科学 | 401篇 |
临床医学 | 2285篇 |
内科学 | 1907篇 |
皮肤病学 | 5676篇 |
神经病学 | 1014篇 |
特种医学 | 864篇 |
外国民族医学 | 3篇 |
外科学 | 3099篇 |
综合类 | 2585篇 |
预防医学 | 1445篇 |
眼科学 | 164篇 |
药学 | 2541篇 |
17篇 | |
中国医学 | 899篇 |
肿瘤学 | 1067篇 |
出版年
2024年 | 98篇 |
2023年 | 554篇 |
2022年 | 827篇 |
2021年 | 1051篇 |
2020年 | 1049篇 |
2019年 | 911篇 |
2018年 | 849篇 |
2017年 | 811篇 |
2016年 | 852篇 |
2015年 | 830篇 |
2014年 | 1307篇 |
2013年 | 1905篇 |
2012年 | 1187篇 |
2011年 | 1410篇 |
2010年 | 1147篇 |
2009年 | 1058篇 |
2008年 | 1099篇 |
2007年 | 1157篇 |
2006年 | 1012篇 |
2005年 | 946篇 |
2004年 | 832篇 |
2003年 | 797篇 |
2002年 | 708篇 |
2001年 | 637篇 |
2000年 | 444篇 |
1999年 | 477篇 |
1998年 | 445篇 |
1997年 | 443篇 |
1996年 | 414篇 |
1995年 | 365篇 |
1994年 | 275篇 |
1993年 | 245篇 |
1992年 | 275篇 |
1991年 | 214篇 |
1990年 | 198篇 |
1989年 | 190篇 |
1988年 | 186篇 |
1987年 | 177篇 |
1986年 | 161篇 |
1985年 | 179篇 |
1984年 | 167篇 |
1983年 | 112篇 |
1982年 | 126篇 |
1981年 | 123篇 |
1980年 | 100篇 |
1979年 | 113篇 |
1978年 | 57篇 |
1977年 | 60篇 |
1976年 | 71篇 |
1975年 | 35篇 |
排序方式: 共有10000条查询结果,搜索用时 0 毫秒
71.
Little is known about whether patients with photosensitive disorders exhibit a different ultraviolet erythema time course from subjects with a normal response to sunlight. We have described the application of an instrument for ambulatory monitoring of the development of ultraviolet erythema by a reflectance method in a group of patients with chronic actinic dermatitis (CAD) and in a group of normal subjects. Investigations of the time course have been reported previously but the techniques used relied upon manual measurement. Consequently sampling frequencies have been considerably lower than the one-minute sample rate used here. We have not demonstrated any difference in the rate at which erythema develops and peaks between patients with CAD and subjects with a normal response to sunlight. 相似文献
72.
面部色素痣较常见于鼻、颊、额、颧区,部分病变累及一侧面部的多个区域。这些病变手术切除后的缺损主要采用全厚皮片移植、直接拉拢缝合或邻近皮瓣整复。 相似文献
73.
74.
皮肤软组织扩张器在整形外科中的应用 总被引:1,自引:0,他引:1
作者应用皮肤软组织扩张器进行软组织缺损修复13例,全鼻再造1例,除1例皮瓣远端血运不佳外,其余病例均获满意效果。本文介绍了皮肤软组织扩张术的优点及适应症,重点讨论了下列问题:①皮肤扩张面积的估计;②扩张囊埋植层次;③注射壶、连接导管的安放位置;④纤维囊的处理;⑤扩张皮瓣的正确设计。 相似文献
75.
76.
77.
目的:探讨使用免缝胶布对伤口减张制动的方法和治疗效果。方法:对62例面部瘢痕或痣切除手术患者,随机分组,45例为治疗组,术后5天拆线,拆线当天开始使用免缝胶布。胶布垂直跨越伤口线粘贴,使创缘处于无张力状态。17例为对照组,未使用免缝胶布。术后6个月对瘢痕进行临床评分,治疗组与对照组对比,统计分析。结果:62例患者伤口均一期愈合,治疗组37位(82%)、对照组4位(23%)患者瘢痕恢复至成熟期,没有痒或刺痛的主观症状,瘢痕颜色淡、平坦、质地软;治疗组5位(11.1%)、对照组13位(76.5%)患者瘢痕增宽,有痒或刺痛的症状,瘢痕颜色红,突出皮面。结论:免缝胶布可以有效地减轻伤口两侧张力,减少瘢痕增生,是一种瘢痕术后重要的辅助治疗。 相似文献
78.
Harun Ulger Nuri Erdogan Sadan Kumanlioglu Erdogan Unur 《Skin research and technology》2003,9(3):284-289
Background/purpose: The localized or generalized skin thickness detected on mammography may reflect an underlying pathology of breast or a systemic disease involving the skin. The aim of this report is to describe the range of normal breast skin thickness in women using a film-screen mammographic technique.
Methods: Measurement of the mammographic skin thickness over different parts of the breast was performed in 144 women who had normal findings in a combined mammographic and ultrasonographic examination. Patients were grouped as premenopause, postmenopause and surgical menopause who were under continuous oestrogen treatment. The skin thickness in four regions (superior, inferior, medial, lateral) of both breasts was compared, and their relations with age, breast size, menopausal and hormonal status were investigated. The interobserver reliability was tested in a small subgroup of patients.
Results: Interobserver agreement was good for all measurements. The range of normal breast skin thickness was between 0.50 and 3.10 mm. There were no differences in skin thickness between the corresponding regions of the breasts, with significant differences between the regions in the same breast. While breast size increased with age, skin thickness decreased in all regions.
Conclusion: The breast size, age, regional variations and hormonal status of the patients should be considered when defining the normal range of skin thickness in mammographic examinations. We assume that upper limit of mammographic skin thickness should be set as 3.0 mm, regardless of the focal spot size and film-focus distance. 相似文献
Methods: Measurement of the mammographic skin thickness over different parts of the breast was performed in 144 women who had normal findings in a combined mammographic and ultrasonographic examination. Patients were grouped as premenopause, postmenopause and surgical menopause who were under continuous oestrogen treatment. The skin thickness in four regions (superior, inferior, medial, lateral) of both breasts was compared, and their relations with age, breast size, menopausal and hormonal status were investigated. The interobserver reliability was tested in a small subgroup of patients.
Results: Interobserver agreement was good for all measurements. The range of normal breast skin thickness was between 0.50 and 3.10 mm. There were no differences in skin thickness between the corresponding regions of the breasts, with significant differences between the regions in the same breast. While breast size increased with age, skin thickness decreased in all regions.
Conclusion: The breast size, age, regional variations and hormonal status of the patients should be considered when defining the normal range of skin thickness in mammographic examinations. We assume that upper limit of mammographic skin thickness should be set as 3.0 mm, regardless of the focal spot size and film-focus distance. 相似文献
79.
术中输注氨基酸对硬膜外阻滞复合全麻开胸手术患者围术期体温的影响 总被引:2,自引:0,他引:2
目的评价术中输注氨基酸对硬膜外阻滞复合全麻食管癌和贲门癌手术患者围术期深部体温和代谢的影响。方法择期食管癌和贲门癌手术患者21例,ASAⅠ或Ⅱ级,随机分为3组(n =7):从麻醉诱导开始至手术结束,分别静脉输注氨基酸混合液240kJ·h-1(AA组)、等容量乳酸钠林格氏液(LR组)、葡萄糖溶液240kJ·h-1(GLU组)。麻醉诱导前至术后2h每5分钟测定鼓膜温度,于麻醉诱导前即刻、手术开始后1h和术后1h检测指尖血糖,采用4分表法评价术后2h内寒战的发生情况,采用间接测热仪测定术前与术后氧耗。结果与麻醉诱导前即刻比较,术后30min LR组和GLU组氧耗降低,AA组氧耗升高(P<0.01),术后2h LR组、GLU组鼓膜温度降低(P<0.05),AA组差异无统计学意义(P>0.05);与LR组和GLU组比较,AA组术后2h内寒战发生例数减少(P< 0.05),术后30min氧耗增多(P<0.05),LR组与GLU组比较差异无统计学意义(P>0.05)。结论硬膜外阻滞复合全麻开胸手术患者术中静脉输注氨基酸可通过提高基础代谢率,缓解围术期深部体温降低,减少术后寒战发生,而输注葡萄糖不产生此效应。 相似文献
80.
TP Amadeu† AB Seabra‡ MG de Oliveira‡ AMA Costa† 《Journal of the European Academy of Dermatology and Venereology》2007,21(5):629-637
BACKGROUND: Nitric oxide (NO) plays a key role in wound repair and S-nitrosothiols like S-nitrosoglutathione (GSNO) are well known NO donors. METHODS: Animals were separated in two groups and submitted to excisional wounds on the dorsal surface at the first day. GSNO (100 microm)-containing hydrogels were topically applied on the wound bed in the GSNO group, daily, during the first 4 days. Control group was topically treated with hydrogel without GSNO for the same period. Wound contraction and re-epithelialization were measured. Animals were sacrificed 21 days after wounding. Samples of lesion and normal tissue were formalin-fixed, paraffin embedded for histological analysis. RESULTS: Wound contraction, measured 14 and 21 days after wounding, was greater in the GSNO group than in the control group (P<0.05 for both). The re-epithelialized wound area, measured 14 days after wounding, was higher in the GSNO group than in the control group (P<0.05). A higher amount of inflammatory cells was observed in superficial and deep areas of the granulation tissue of the control group compared to the GSNO group. Twenty-one days after wounding, thin red-yellow collagen fibers arranged perpendicularly to the surface were found in the granulation tissue of the control group, whereas in the GSNO-treated group collagen fibers were thicker and arranged parallel to the surface. Increased number of mast cells was observed in the GSNO group compared with that in the control group. Vascularization and myofibroblast distribution were similar in both groups. CONCLUSION: Topical application of GSNO-containing hydrogel during the early phases of rat cutaneous wound repair accelerates wound closure and re-epithelialization and affects granulation tissue organization. 相似文献