SCAI expert consensus statement for femoral‐popliteal arterial intervention appropriate use

Successful endovascular intervention for femoral‐popliteal (FP) arterial disease provides relief of claudication and offers limb‐salvage in cases of critical limb ischemia. Technologies and operator technique have evolved to the point where we may now provide effective endovascular therapy for a spectrum of lesions, patients, and clinical scenarios. Endovascular treatment of this segment offers a significant alternative to surgical revascularization, and may confer improved safety for a wide range of patients, not solely those deemed high surgical risk. Although endovascular therapy of the FP segment has historically been hampered by high rates of restenosis, emerging technologies including drug‐eluting stents, drug‐coated balloons, and perhaps bio‐absorbable stent platforms, provide future hope for more durable patency in complex disease. By combining lessons learned from clinical trials, international trends in clinical practice, and insights regarding emerging technologies, we may appropriately tailor our application of endovascular therapy to provide optimal care to our patients. This document was developed to guide physicians in the clinical decision‐making related to the contemporary application of endovascular intervention among patients with FP arterial disease. © 2014 Wiley Periodicals, Inc.     

Lower Extremity Revascularization Using Directional Atherectomy: 12-Month Prospective Results of the DEFINITIVE LE Study

ObjectivesThe aim of this study was to assess the safety and effectiveness of directional atherectomy (DA) for endovascular treatment of peripheral arterial disease (PAD) in infrainguinal arteries in patients with claudication or critical limb ischemia.BackgroundTo date, no prospective, multicenter, independently-adjudicated study has evaluated the effectiveness and durability of DA in the treatment of PAD. Previous DA studies have not been prospectively powered to evaluate any differences in outcomes in patients with and without diabetes.MethodsDEFINITIVE LE (Determination of EFfectiveness of the SilverHawk® PerIpheral Plaque ExcisioN System (SIlverHawk Device) for the Treatment of Infrainguinal VEssels / Lower Extremities) prospectively enrolled subjects at 47 multinational centers with an infrainguinal lesion length up to 20 cm. Primary endpoints were defined as primary patency at 12 months for claudicants and freedom from major unplanned amputation for critical limb ischemia (CLI) subjects. A pre-specified statistical hypothesis evaluated noninferiority of primary patency in diabetic versus nondiabetic claudicants. Independent angiographic and sonographic core laboratories assessed outcomes, and events were adjudicated by a clinical events committee.ResultsA total of 800 subjects were enrolled. The 12-month primary patency was 78% (95% confidence interval: 74.0% to 80.6%) in claudicants, with a 77% rate in the diabetic subgroup versus 78% in the nondiabetic subgroup (noninferior, p < 0.001). The rate of freedom from major unplanned amputation of the target limb at 12 months in CLI subjects was 95% (95% confidence interval: 90.7% to 97.4%). Periprocedural adverse events included embolization (3.8%), perforation (5.3%), and abrupt closure (2.0%). The bail-out stent rate was 3.2%.ConclusionsThe DEFINITIVE LE study demonstrated that DA is a safe and effective treatment modality at 12 months for a diverse patient population with either claudication or CLI. Furthermore, DA was shown to be noninferior for treating PAD in patients with diabetes compared with those without diabetes. (Study of SilverHawk/TurboHawk in Lower Extremity Vessels [DEFINITIVE LE]; NCT00883246).     

The effects of a bare metal stent on the healing of a huge coronary pseudoaneurysm: A case report

We experienced a rapidly growing huge coronary pseudoaneurysm with symptomatic restenosis after rotational atherectomy. A BMS had successfully obliterated the huge coronary pseudoaneurysm at 3 months follow‐up on CTA. The OCT at 9 months follow‐up showed that the most of stent strut was covered with neo‐intima. This case suggests that BMS deployment is recommended as a useful method for treating coronary pseudoaneurysms. © 2011 Wiley Periodicals, Inc.     

手指旋转撕脱性离断再植的临床研究

目的探讨手指旋转撕脱性离断再植方法及临床疗效。方法2007年5月-2011年9月对21例30指旋转撕脱性离断的断指进行再植,根据手指旋转撕脱离断的程度,分别采用血管移植、血管神经束转位、带血管皮瓣转移等方法重建血循环及感觉。结果30指成活29指,失败1指,成活率96．7％。术后随访20例,随访时间6个月～3年,平均1年5个月,以最后一次随访结果为准,按中华医学会手外科学会上肢部分功能评定试用标准评定：优20指,良7指。差3指,优良率90％。结论按照手指旋转撕脱性离断伤不同情况采用不同再植方法,可获得较高的成活率,并能恢复较好的外形与功能。     

Hip range‐of‐motion (ROM) is less than normal after rotational acetabular osteotomy for developmental dysplasia of the hip: A simulated ROM analysis

The optimal reorientation of the acetabulum for developmental dysplasia of the hip (DDH) is unknown in terms of hip range‐of‐motion (ROM). The simulated ROMs of 52 DDHs after rotational acetabular osteotomy (RAO) with several patterns of femoral head coverage and those of 73 normal hips were analyzed using computer models reconstructed from CT images. After RAO with a lateral center edge angle (LCEA) of 30° and an anterior center edge angle (ACEA) of 55° producing coverage similar to that of normal hips, the maximal flexion and maximal internal rotation at 110° flexion with 20° adduction were significantly smaller than those of the normal group. To achieve ROMs after RAO similar to those of the normal group, an LCEA of 30° with an ACEA of 45°, an LCEA of 25° with an ACEA of 45° to 50°, and an LCEA of 20° with an ACEA of 50° could be preferred angles to target, even though they provided smaller coverage than that of normal hips. After RAO producing femoral head coverage similar to that of normal hips, the maximal flexion and the maximal internal rotation at 110° flexion with 20° adduction were significantly smaller than those of the normal group. © 2015 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 34:217–223, 2016.     

系统性护理干预对乳腺微创旋切术患者心理及康复情况的影响分析

目的:探究系统性护理干预对乳腺微创旋切术患者心理状态及康复情况的影响。方法:将120例接受乳腺微创旋切术治疗的患者随机分为观察组(60例)和对照组(60例)。对照组采用常规护理干预,观察组采用系统性护理干预。比较两组患者术后疼痛、心理状态、并发症发生情况及对护理的满意度。结果:观察组护理满意度96.67%显著高于对照组的80.00%,观察组并发症发生率6.67%显著低于对照组的30.00%,差异有统计学意义(P<0.05)。观察组术后2h、6h、12h、24h的疼痛数字等级评定量表(Numerical rating scale,NRS)评分低于对照组,且观察组抑郁自评量表(Self-rating depression scale,SDS)评分、焦虑自评量表(Self-rating anxiety scale,SAS)评分均低于对照组,依从性评分显著高于对照组,差异有统计学意义(P<0.05)。结论:系统性护理干预在乳腺微创旋切术中应用效果良好,可有效降低并发症发生率,减轻患者疼痛及负性心理,提高其依从性及护理满意度,值得临床推广应用。