全文获取类型
收费全文 | 190916篇 |
免费 | 14308篇 |
国内免费 | 4414篇 |
专业分类
耳鼻咽喉 | 1366篇 |
儿科学 | 2952篇 |
妇产科学 | 3149篇 |
基础医学 | 23680篇 |
口腔科学 | 3364篇 |
临床医学 | 15193篇 |
内科学 | 30149篇 |
皮肤病学 | 2185篇 |
神经病学 | 12036篇 |
特种医学 | 6690篇 |
外国民族医学 | 1篇 |
外科学 | 15299篇 |
综合类 | 25121篇 |
现状与发展 | 23篇 |
一般理论 | 8篇 |
预防医学 | 14923篇 |
眼科学 | 2281篇 |
药学 | 25527篇 |
60篇 | |
中国医学 | 12574篇 |
肿瘤学 | 13057篇 |
出版年
2024年 | 360篇 |
2023年 | 2435篇 |
2022年 | 4955篇 |
2021年 | 7840篇 |
2020年 | 6661篇 |
2019年 | 6653篇 |
2018年 | 6642篇 |
2017年 | 7110篇 |
2016年 | 7088篇 |
2015年 | 6714篇 |
2014年 | 7746篇 |
2013年 | 11582篇 |
2012年 | 9266篇 |
2011年 | 11264篇 |
2010年 | 7050篇 |
2009年 | 7238篇 |
2008年 | 8781篇 |
2007年 | 9823篇 |
2006年 | 9321篇 |
2005年 | 8616篇 |
2004年 | 7405篇 |
2003年 | 6658篇 |
2002年 | 5282篇 |
2001年 | 4844篇 |
2000年 | 4093篇 |
1999年 | 3482篇 |
1998年 | 2787篇 |
1997年 | 2891篇 |
1996年 | 2614篇 |
1995年 | 2311篇 |
1994年 | 2192篇 |
1993年 | 1876篇 |
1992年 | 1742篇 |
1991年 | 1599篇 |
1990年 | 1349篇 |
1989年 | 1089篇 |
1988年 | 1061篇 |
1987年 | 973篇 |
1986年 | 888篇 |
1985年 | 1275篇 |
1984年 | 1023篇 |
1983年 | 776篇 |
1982年 | 801篇 |
1981年 | 640篇 |
1980年 | 618篇 |
1979年 | 491篇 |
1978年 | 304篇 |
1977年 | 263篇 |
1976年 | 247篇 |
1975年 | 188篇 |
排序方式: 共有10000条查询结果,搜索用时 31 毫秒
51.
52.
Primary cutaneous anaplastic large cell lymphomas with 6p25.3 rearrangement exhibit particular histological features
下载免费PDF全文
![点击此处可从《Histopathology》网站下载免费的PDF全文](/ch/ext_images/free.gif)
53.
Evaluation of Adult versus Pediatric Transesophageal Echocardiography Probe Efficiency for Guiding Septal Puncture during Atrial Fibrillation Ablation
下载免费PDF全文
![点击此处可从《Echocardiography (Mount Kisco, N.Y.)》网站下载免费的PDF全文](/ch/ext_images/free.gif)
54.
Tianying Yang Jiawei Li Yichen Jia Chunchen Yang Ruirui Sang Tongyu Zhu Ming Xu Ruiming Rong Cheng Yang 《Translational andrology and urology》2021,10(1):204
BackgroundIn the field of transplantation, inducing immune tolerance in recipients is of great importance. Blocking co-stimulatory molecule using anti-CD28 antibody could induce tolerance in a rat kidney transplantation model. Myeloid-derived suppressor cells (MDSCs) reveals strong immune suppressive abilities in kidney transplantation. Here we analyzed key genes of MDSCs leading to transplant tolerance in this model.MethodsMicroarray data of rat gene expression profiles under accession number in the Gene Expression Omnibus (GEO) database were analyzed. Running the LIMMA package in R language, the differentially expressed genes (DEGs) were found. Enrichment analysis of the DEGs was conducted in the Database for Annotation, Visualization and Integrated Discovery (DAVID) database to explore gene ontology (GO) annotation and their Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways. Their protein-protein interactions (PPIs) were provided by STRING database and was visualized in Cytoscape. Hub genes were carried out by CytoHubba.ResultsThree hundred and thirty-eight DEGs were exported, including 27 upregulated and 311 downregulated genes. The functions and KEGG pathways of the DEGs were assessed and the PPI network was constructed based on the string interactions of the DEGs. The network was visualized in Cytoscape; the entire PPI network consisted of 192 nodes and 469 edges. Zap70, Cdc42, Stat1, Stat4, Ccl5 and Cxcr3 were among the hub genes.ConclusionsThese key genes, corresponding proteins and their functions may provide valuable background for both basic and clinical research and could be the direction of future studies in immune tolerance, especially those examining immunocyte-induced tolerance. GSE28545相似文献
55.
56.
目的 了解某设备实验条件下不同位置脉冲X射线电离辐射水平,提出适当的防护建议。方法 采用热释光测量方法,分别在设备舱周围不同方向不同距离布放热释光剂量计,累积一定数量脉冲辐射后进行测量;采用电离室型X、γ剂量率仪(FJ-347A)实时测量工作状态下不同距离处电离辐射剂量率水平。依据《电离辐射防护与辐射源安全基本标准》(GB18871—2002)规定的职业照射人员和公众个人剂量限值提出不同工作位辐射防护建议。结果 热释光剂量计累计接收3 000个脉冲辐射,设备舱外壁0.01~8.98 mGy,顶部0.01~15.67 mGy,距外壁1~12 m之间0.01~2.18 mGy,工作位0 mGy。工作状态下,X射线剂量率仪测得距设备舱外侧壁1~20 m之间空气比释动能率范围0.26~16 mGy/h。结论 热释光剂量计、电离室型剂量率仪测量结果基本一致,说明两种方法均可用于脉冲X射线测量;工作状态下设备舱外近距离处辐射剂量率较高,可通过采取防护措施或者限制人员工作量以满足辐射防护要求。 相似文献
57.
58.
Assessment of Myocardial Infarct Size by Three‐Dimensional and Two‐Dimensional Speckle Tracking Echocardiography: A Comparative Study to Single Photon Emission Computed Tomography
下载免费PDF全文
![点击此处可从《Echocardiography (Mount Kisco, N.Y.)》网站下载免费的PDF全文](/ch/ext_images/free.gif)
59.
《The Journal of emergency medicine》2020,58(2):e47-e50
BackgroundBupropion overdose is a commonly encountered presentation in the emergency department (ED). While the majority of cases resolve with supportive care, serious adverse effects, including seizures, cardiogenic shock, and death, can occur. Intravenous lipid emulsion (ILE) therapy has been utilized for a multitude of poisonings with varying levels of success. Although a number of cases suggest the value of ILE therapy in cases of bupropion overdose, more recent data propose that its role may be overstated.Case ReportA young woman presented to the ED with altered mental status complicated by seizure after bupropion overdose. She subsequently developed cardiogenic shock requiring vasopressor support. Bedside echocardiogram revealed a decreased left ventricular ejection fraction (LVEF). She received ILE therapy with significant improvement in both hemodynamic status and LVEF by bedside ultrasound.Why Should an Emergency Physician Be Aware of This?Although the majority of patients presenting with bupropion overdose improve with supportive care, life-threatening sequelae are possible. ILE therapy has shown promise in a variety of different overdose situations, although the evidence in cases of bupropion poisoning has been varied, and it has traditionally been utilized as a last-line rescue modality. Based on hemodynamic parameters and bedside ultrasound, this case suggests that early initiation of ILE therapy should be considered in these cases, as the potential benefits likely outweigh the theoretical risks. 相似文献
60.
Feasibility and Diagnostic Potential of Pulmonary Transit Time Measurement by Contrast Echocardiography: A Pilot Study
下载免费PDF全文
![点击此处可从《Echocardiography (Mount Kisco, N.Y.)》网站下载免费的PDF全文](/ch/ext_images/free.gif)