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51.
近年来传统医药保护问题获得世界各国普遍关注.其中,泰国推出了以国家立法形式对传统医药知识做特殊保护的方法,对发展中国家具有一定借鉴作用.本文在介绍泰国传统医药知识产权保护政策基础上,对我国中医药知识产权保护方法提出了构想. 相似文献
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ObjectiveThe present study aimed at examining the effects of a Thai Boxing dance (TBD) program on balance performances and functional fitness in community-dwelling older adults at risk of falling who have no comorbidities leading to falls.MethodsSeventy-eight participants were randomly equally assigned either to a 4-week TBD program or to a control group receiving a fall prevention booklet. Static and dynamic balance performances, and functional fitness including lower limb muscle strength, body flexibility, and agility were evaluated before and after the intervention, and at 4-month follow-up.ResultsAfter receiving 4-week TBD intervention, participants showed significantly greater improvements in static balance with eyes open, dynamic balance and all functional fitness when compared to the control group (p < 0.05), and these effects except for body flexibility were still maintained at 4-month follow-up (p < 0.05).ConclusionsThis study highlights TBD as an intervention for improving balance and functional fitness of community-dwelling seniors at risk of falling. 相似文献
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ObjectiveTo determine the anti-Streptococcus mutans mechanisms of action of lupinifolin from Albizia myriophylla Benth. (Fabaceae) wood and provide scientific evidence to support the traditional use of the plant against dental caries.MethodsThe minimum inhibitory concentration (MIC) was evaluated using the broth micro-dilution method. The effects of lupinifolin on bactericidal activity, bacterial cell walls, and membranes were investigated by time-kill, lysis, and leakage assays, respectively. Electron microscopy was utilized to observe any cell morphological changes caused by the compound. Localization of lupinifolin in S. mutans was detected using the thin layer chromatography technique.ResultsThe MIC range of lupinifolin against S. mutans (n = 6) was 2–4 μg/ml. This compound displayed bactericidal effects on S. mutans ATCC 25175 by 90–99.9% killing at 4MIC-16MIC after 8–24 hours. Lupinifolin-treated cells demonstrated no lysis. However, significant cytoplasmic leakage through the bacterial membrane was observed after treatment with lupinifolin at 4MIC-16MIC. As revealed by ultrastructural analysis, lupinifolin produced some changes in bacterial cell walls and membranes. Moreover, the compound was observed in the cytoplasmic fraction of the lupinifolin-treated cells. These results suggest that lupinifolin can enter the cell of bacteria but does not accumulate in the cell envelope and subsequently disrupts the integrity of the cytoplasmic membrane, leading to cell death.ConclusionThe scientific evidence from this study offers valuable insights into the potential role of lupinifolin in pharmaceutical and antibiotic applications and supports the therapeutic effects of A. myriophylla, which has traditionally been used as an alternative treatment for dental caries. 相似文献
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Dusanee SuwankhongPranee Liamputtong 《Asian Pacific journal of cancer prevention》2018,19(4):1089-1097
Background: Breast cancer screening programme is seen as the best practice to detect breast cancer early. However,there are circumstances that can prevent immigrant women from attending screening programmes. Little is knownabout Thai migrants and the barriers to their seeking breast cancer screening when living in a new homeland. This paperaimed to discuss the barriers to attending screening services among Thai migrant women living in Australia. Methods:This study adopted qualitative approach. Semi-structured in-depth interviewing and drawing methods were employedas data collection technique with 25 Thai migrant women who had not experienced breast cancer and were living inMetropolitan Melbourne, Australia. Thematic analysis method was employed to analyse the data. Results: Basing onthe Health Belief Model, most Thai migrant women did not perceive that they were at risk of breast cancer. Despiteseeing a breast cancer screening programme as important, the women rarely paid attention to breast cancer screeningand used the mammography services provided by the Australian health care system. The barriers included the locationof the services, unfamiliar patterns of health care provision, and language difficulties. Conclusions: There are manybarriers that that they encountered in Australia that prevent Thai migrant women living in Melbourne Australia to payattention to mammographic screening service provided by Australia health system. Our findings suggest that healthservices and interventions need to be designed more sensitive to the needs and socio-cultural context of migrant womenin general and Thai migrant women in particular. 相似文献
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Supitcha Wanvimonsuk Pichaya Thitiwanichpiwong Somboon Keelawat Apiwat Mutirangura Nakarin Kitkumthorn 《Journal of medical virology》2019,91(3):444-449
The Epstein-Barr virus (EBV) is one of the infectious agents found in stomach tissue. Recently, EBV-associated gastric carcinoma (EBVaGC) was classified as a new subtype of gastric carcinoma. To date, there is a lack of knowledge about the distribution and prevalence of EBV infection in both the normal stomach and various gastric lesions, including EBVaGC, in the Thai population. In this study, we detected EBV in the normal stomach (NS; n = 19), chronic gastritis (CG; n = 36), intestinal metaplasia (IM; n = 40), gastric dysplasia (GD; n = 15), and gastric adenocarcinoma (GC; n = 33) by polymerase chain reaction (PCR) amplification of the latent membrane protein (LMP1) gene of EBV. EBV-PCR amplification was positive in 42.1%, 36.1%, 22.5%, 13.3%, and 33.3% of NS, CG, IM, GD, and GC, respectively. For further clarification in EBVaGC, we performed EBV-encoded small RNA in situ hybridization (EBER-ISH) in PCR-positive cases of GD and GC. Four GC cases were EBER-ISH positive (12.1%), while both GD cases were EBER-ISH negative. In addition, we determined the distribution of the EBV strain (type A or B) based on EBNA3C sequence and EBV variants based on LMP1 variation (wild-type and 30-bp deletion variants; wt-LMP1 or del-LMP1). The results showed that type A and wt-LMP1 were the most prevalent in all lesions. In conclusion, EBV is common in both the NS and gastric lesions, and the frequency of EBVaGC was 12.1% in Thai patients. 相似文献
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Andrew C. Mills Jidapa Poogpan Choochart Wong‐Anuchit Darunee Rujkorakarn 《International journal of mental health nursing》2019,28(4):879-887
The purpose of this qualitative study was to explore the meaning of acceptance (Thum‐jai) as a culturally embedded coping strategy in the lives of Thai people who have experienced adversity that caused suffering. Thematic analysis was used to examine the responses of 47 participants to written, open‐ended questions or face‐to‐face interviews. The EQUATOR's COREQ checklist for qualitative research was followed. Participants came from diverse religious’ traditions and geographic regions throughout Thailand. Findings revealed seven themes: circumstance and emotion; thought and action; time, experience, and effort; social and moral support; religious and spiritual ethos; acceptance and hope; and survive and thrive. The adverse circumstance is central to the concept of acceptance. Before acceptance, there is often hope; yet Thai people reach an existential point whether to accept the reality of the situation or continue in distress. Purposeful approaches to deal with the event flow from the cultural contexts of spirituality and social support. Drawing upon psychological strength, Thai people undertake purposive thought and action to facilitate redirecting their lives for better mental health. Thum‐jai brings release and peace of mind. Clinicians may find that people experiencing adverse life events are best served by nondirective approaches. Acceptance and change in thoughts and behaviours may come from meditation and therapeutic mindfulness practices that allow those in Western and non‐Western cultures to use their own values, expressions, and societal expectations to cope with suffering and formulate effective decisions. 相似文献