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Stefanie Soder Thomas L. Diepgen Magdalena Radulescu Christian J. Apfelbacher Thomas Bruckner Elke Weisshaar 《Journal der Deutschen Dermatologischen Gesellschaft》2007,5(8):670-676
Background: Cleaning and kitchen employees have an increased risk of suffering from occupational dermatoses. Prevention including improving individual skin care and skin protection behavior, health education, optimizing diagnostics and therapy as well as avoidance of occupational skin disease (BK 5101) is important. Patients and methods: Participants in the courses were patients suspected of having an occupational skin disease. Besides socio‐demographic and diseaserelated data, health‐related quality of life (QL) was measured using the SF‐36 and Skindex‐29. One year later all participants were interviewed by telephone about the course of their skin disease. Results: Out of 212 participants, 84.0 % were female. The mean age was 41.6 (SD = 10.8) years.168 patients (79.2 %) suffered from hand dermatitis,with irritant contact dermatitis being the predominant diagnosis (46.2 %,n = 98).One year later 65.4 % (n = 85) of the patients interviewed still suffered from hand der‐matitis.9.2 % (n = 12) had meanwhile quit their job due to the skin disease.QL was impaired in all age groups being lower with increasing age of the patients. Conclusions: The follow‐up confirmed the positive impact of the skin protection courses on patients' skin disease and well‐being. Occupational skin diseases impair health‐related quality of life in these professions but disease severity does not seem to play a key role. 相似文献
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Eun-Seok Choi Hyun Dae Shin Jae Ang Sim Young Gon Na Won-Jun Choi Dae-Do Shin Jong-Min Baik 《Clinics in Orthopedic Surgery》2021,13(1):60
BackgroundOsteoarthritis (OA) and osteoporosis (OP) are the 2 most common bone disorders associated with aging. We can simply assume that older patients have a higher incidence of OA and OP with more severity. Although several papers have conducted studies on the relationship between OA and OP, none of them has demonstrated a conclusive link. In this study, we used radiological knee OA and bone mineral density (BMD; T-score of the total hip and lumbar spine) to analyze the incidence of OA and OP in a large population. We aimed to determine the relationship between OA and OP and investigate the associated risk factorsMethodsThis cross-sectional study used data extracted from the 2010–2012 Korea National Health and Nutrition Examination Survey. We evaluated a total of 4,250 participants aged ≥ 50 years who underwent knee radiography and dual-energy X-ray absorptiometry and their laboratory results. The relationship between radiological knee OA and BMD was assessed. The generalized linear model was used to evaluate the relationship between BMD and Kellgren-Lawrence (KL) grade.ResultsThe higher KL grade was associated with older age, higher body mass index (BMI), female sex, and lower hemoglobin level (p < 0.001). No significant association was found between OA and the following variables: white blood cell, platelet, total cholesterol, vitamin D, alkaline phosphatase, parathyroid hormone, hypertension, diabetes, asthma, dyslipidemia, smoking status, alcohol consumption, and regular exercise (p > 0.05). After adjusting for confounding factors (age, BMI, diabetes, hypertension, smoking, and alcohol consumption), the average T-scores of total hip and lumbar spine were the highest in the mild OA group with KL grade 2 (−0.22 ± 1.08 and −0.89 ± 1.46, respectively, p < 0.001). The average T-scores of the total hip and lumbar spine significantly decreased as OA progressed from moderate (KL grade 3; −0.49 ± 1.05 and −1.33 ± 1.38, respectively, p < 0.001) to severe (KL grade 4; −0.73 ± 1.13 and −1.74 ± 1.75, respectively, p < 0.001). T-scores of the moderate-to-severe OA group were significantly lower than those of the non-OA group (KL grades 0 and 1, p < 0.001).ConclusionsCompared with the non-OA group, BMD (T-scores of the total hip and lumbar spine) was higher in the mild OA group and lower in the moderate-to-severe OA group. 相似文献
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